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Herpes Drugs in Development


OrganismDrug ClassCompanyDrug NameAlt NameDrug StatusNotesAIDS#
Epstein-Barr virusCombination Phenylbutyrate and Valganciclovir  Phase IIUnknown
Epstein-Barr virusCombinationHemaQuest Pharmaceuticals Inc.Ganciclovir and Arginine Butyrate Phase IITerminated
Epstein-Barr virusVirus Replication InhibitorGSKValtrex™ ValacyclovirPhase IICompleted 070982
Herpes simplex virusBlocks Virus morphogenesisDeNova ResearchBotox™Botulinum Toxin A; Onabotulinumtoxin APhase IIOngoing, Not Recruiting
Herpes simplex virusDNA Helicase InhibitorAiCuris AIC-316 Phase IICompleted
Herpes simplex virusEntry InhibitorShaman PharmaceuticalsVirend™Crofelemer; SP-303TPhase IICompleted 071298
Herpes simplex virusHelicase-primase InhibitorAstellas Pharma IncASP2151 Phase IIIEnrolment by Invitation 501812
Herpes simplex virusUnknownZicamZicam™Ionic ZincPhase IIIUnknown
Herpes simplex virusVirucidalNanoBio Corporation; GlaxoSmithKlineNB-001 Phase IIICompleted
Herpes simplex virusVirus Replication InhibitorBeech Tree Labs, Inc.BTL-TML-HSV Phase IIRecruiting
Herpes simplex virusVirus Replication InhibitorOclassen PharmaceuticalsFialuridineFIAUPhase IICompleted 070971
Herpes simplex virusVirus Replication InhibitorParkedale PharmaceuticalsVira-A™VidarabinePhase IIICompleted 007328
Herpes simplex virusVirus Replication InhibitorGilead SciencesForvade™Cidofovir gelPhase IICompleted 001049
Human cytomegalovirusHCMV Maturation InhibitorBayerBAY 38-4766 Preclinical  085779
Human cytomegalovirusHCMV Replication InhibitorTrifecta Pharmaceuticals Artesunate Phase IIICompleted 112081
Human cytomegalovirusHCMV Terminase-Complex InhibitorAiCuris LetermovirAIC246 Phase IICompleted 499605
Human cytomegalovirusUL97 Kinase InhibitorGlaxoSmithKline, ViroPharmaMaribavirBenzimidavir; 1263W94; G1263Phase IIICompleted 070966
Human cytomegalovirusVirus Replication InhibitorMicrobiotix, Inc.; Karmanos Cancer InstituteCyclopropavir CPV;ZSM-I-62 MBX400Phase ICompleted 165691
Human cytomegalovirusVirus Replication InhibitorGilead SciencesPreveon™; Hepsera™Adefovir Dipivoxil; bis-POM PMEAPhase IIICompleted 028595
Human cytomegalovirusVirus Replication InhibitorChimerixBrincidofovirCMX001; Cidofovir prodrugPhase IIIRecruiting 104906
Kaposi sarcoma virusMatrix Metalloproteinase InhibitorBristol-Myers SquibbRebimastatBMS-275291Phase I/IICompleted
Kaposi sarcoma virusProtease InhibitorMerckCrixivan™IndinavirPhase IICompleted 005824
Kaposi sarcoma virusTyrosine Kinase InhibitorNovartisGleevec™Imatinib MesylatePhase IICompleted 553065
Kaposi sarcoma virusVEGF ModulatorPTC TherapeuticsPTC299  Phase I/II Terminated

Last Updated: January 2014