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Herpes Drugs in Development


OrganismDrug ClassCompanyDrug NameAlt NameDrug StatusNotesAIDS#
Epstein-Barr virusCombination Phenylbutyrate and Valganciclovir  Phase 2Unknown 
Epstein-Barr virusCombinationHemaQuest Pharmaceuticals Inc.Ganciclovir and Arginine Butyrate Phase 2Terminated 
Epstein-Barr virusVirus Replication InhibitorGSKValtrex™ ValacyclovirPhase 3Completed 070982
Herpes simplex virusBlocks Virus morphogenesisDeNova ResearchBotox™Botulinum Toxin A; Onabotulinumtoxin APhase 2Completed 
Herpes simplex virusDNA Helicase InhibitorAiCuris PritelivirAIC-316Phase 2Terminated 
Herpes simplex virusEntry InhibitorShaman PharmaceuticalsVirend™Crofelemer; SP-303TPhase 2Completed 071298
Herpes simplex virusHelicase-primase InhibitorAstellas Pharma IncASP2151 Phase 3Recruiting 501812
Herpes simplex virusUnknownZicamZicam™Ionic ZincPhase 3Completed 
Herpes simplex virusVirucidalNanoBio Corporation; GlaxoSmithKlineNB-001 Phase 3Completed 
Herpes simplex virusVirus Replication InhibitorParkedale PharmaceuticalsVira-A™VidarabinePhase 3Completed 007328
Herpes simplex virusVirus Replication InhibitorGilead SciencesForvade™Cidofovir gelPhase 2Completed 001049
Herpes simplex virusVirus Replication InhibitorOclassen PharmaceuticalsFialuridineFIAUPhase 2Completed 070971
Herpes simplex virusVirus Replication InhibitorBeech Tree Labs, Inc.BTL-TML-HSV Phase 2Completed 
Human cytomegalovirusHCMV Maturation InhibitorBayerBAY 38-4766 Preclinical  085779
Human cytomegalovirusHCMV Replication InhibitorTrifecta Pharmaceuticals Artesunate Phase 3Completed 112081
Human cytomegalovirusHCMV Terminase-Complex InhibitorAiCuris LetermovirAIC246 Phase 3Recruiting 499605
Human cytomegalovirusUL97 Kinase InhibitorGlaxoSmithKline, ViroPharmaMaribavirBenzimidavir; 1263W94; G1263Phase 3Completed 070966
Human cytomegalovirusVirus Replication InhibitorGilead SciencesPreveon™; Hepsera™Adefovir Dipivoxil; bis-POM PMEAPhase 3Completed 028595
Human cytomegalovirusVirus Replication InhibitorChimerixBrincidofovirCMX001; Cidofovir prodrugPhase 3Recruiting 104906
Human cytomegalovirusVirus Replication InhibitorMicrobiotix, Inc.; Karmanos Cancer InstituteCyclopropavir CPV;ZSM-I-62 MBX400Phase 1Completed 165691
Kaposi sarcoma virusMatrix Metalloproteinase InhibitorBristol-Myers SquibbRebimastatBMS-275291Phase 2/3Completed 
Kaposi sarcoma virusProtease InhibitorMerckCrixivan™IndinavirPhase 2Active, Not Recruiting 005824
Kaposi sarcoma virusTyrosine Kinase InhibitorNovartisGleevec™Imatinib MesylatePhase 2Completed 553065
Kaposi sarcoma virusVEGF ModulatorPTC TherapeuticsPTC299  Phase 1/2 Terminated 

Last Updated: April 2015