| AUTHOR |
TITLE |
JOURNAL |
VOLUME |
PAGES |
YEAR |
LITERATURE DATA SEARCH |
| MANJUNATHA, U; BOSHOFF, H; DOWD, C; ZHANG, L; ALBERT, T; NORTON, J; DANIELS, L; DICKL, T; PANG, S; BARRY, C |
IDENTIFICATION OF A NITROIMIDAZO-OXAZINE-SPECIFIC PROTEIN INVOLVED IN PA-824 RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS |
PROC NATL ACAD SCI U S A |
103(2) |
431-436 |
2006 |
|
| |
| NUERMBERGER, E; ROSENTHAL, I; TYAGI, S; WILLIAMS, K; ALMEIDA, D; PELOQUIN, C; BISHAI, W; GROSSET, J |
COMBINATION CHEMOTHERAPY WITH THE NITROIMIDAZOPYRAN PA-824 AND FIRST-LINE DRUGS IN A MURINE MODEL OF TUBERCULOSIS |
ANTIMICROB AGENTS CHEMOTHER |
50(8) |
2621-2625 |
2006 |
|
| |
| TYAGI, S; NUERMBERGER, E; YOSHIMATSU, T; WILLIAMS, K; ROSENTHAL, I; LOUNIS, N; BISHAI, W; GROSSET, J |
BACTERICIDAL ACTIVITY OF THE NITROIMIDAZOPYRAN PA-824 IN A MURINE MODEL OF TUBERCULOSIS |
ANTIMICROB AGENTS CHEMOTHER |
49(6) |
2289-2293 |
2005 |
|
| |
| LENAERTS, AJ; GRUPPO, V; MARIETTA, KS; JOHNSON, CM; DRISCOLL, DK; TOMPKINS, NM; ROSE, JD; REYNOLDS, RC; ORME, IM |
PRECLINICAL TESTING OF THE NITROIMIDAZOPYRAN PA-824 FOR ACTIVITY AGAINST MYCOBACTERIUM TUBERCULOSIS IN A SERIES OF IN VITRO AND IN VIVO MODELS |
ANTIMICROB AGENTS CHEMOTHER |
49(6) |
2294-2301 |
2005 |
|
| |
| LENAERTS, AJ; MARIETTA, KS; GRUPPO, V; JOHNSON, CM; NEAR, KA; LAUGHON, BE; ROUSE, D; ORME, IM |
EFFICACY OF THE NITROIMIDAZOPYRAN PA-824 IN TUBERCULOSIS ANIMAL MODELS(ABSTRACT F-1118) |
44TH ICAAC ABSTRACTS |
44 |
ABSTR F-1118 |
2004 |
|
| |
| STOVER, CK; WARRENER, P; VANDEVANTER, DR; SHERMAN, DR; ARAIN, TM; LANGHORNE, MH; ANDERSON, SW; TOWELL, JA; YUAN, Y; MCMURRAY, DN; KREISWIRTH, BN; BARRY, CE; BAKER, WR |
A SMALL-MOLECULE NITROIMIDAZOPYRAN DRUG CANDIDATE FOR THE TREATMENT OF TUBERCULOSIS |
NATURE |
405(6789) |
962-966 |
2000 |
|
| |
| SHARMA, PAWAN |
A NEW, BROAD-SPECTRUM ANTI-TUBERCULAR DRUG ON THE HORIZON |
CURRENT SCIENCE |
79(4) |
400-401 |
2000 |
|
| |
| STOVER, CK; YUAN, Y; WARRENER, PG; VAN DEVANTER, DR; SHERMAN, DR; LANGHORNE, MH; TANAKA, K; BARRY, CE; BAKER, WR |
A NOVEL COMPOUND SERIES AND DEVELOPMENT CANDIDATE FOR THE TREATMENT OF TUBERCULOSIS(ABSTRACT) |
AM J RESPIR CRIT CARE MED |
159(3) SUPPL S |
A16(ABSTR) |
1999 |
|
| |
| BAKER, WR; SHAOPEI, C; KEELER, EL |
NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF(PATENT TO PATHOGENESIS CORPORATION, UNITED STATES) |
PATENT: US |
5668127 |
34 PP |
1997 |
|
| |
| ANDERSON, SW; ARAIN, TM; SHERMAN, DR |
IN VITRO ANTIMYCOBACTERIAL ACTIVITY OF THE NITROIMIDAZOPYRAN COMPOUND, PA-824, UNDER LOW OXYGEN CONDITIONS(POSTER SESSION 15-F)(ABSTRACT F-25) |
37TH ICAAC ABSTRACTS |
37 |
150(ABSTR F-25) |
1997 |
|
| |
| NYWALL, C; ADAMS, P; ORTA, GJ; IHLE, NC |
INTRAVENOUS PHARMACOKINETICS AND ORAL BIOAVAILABILITY OF BICYCLIC 6-NITROIMIDAZOPYRANS IN FEMALE BALB/C MICE(POSTER SESSION 15-F)(ABSTRACT F-28) |
37TH ICAAC ABSTRACTS |
37 |
150(ABSTR F-28) |
1997 |
|
| |
| RITCHIE, HD; ORTA, GJ; HARRIS, LM; ADAMS, PC; NYWALL, CS; ARAIN, TM |
TOXICOLOGY AND TOXICOKINETICS OF PA-824 AND PA-1297, TWO NITROIMIDAZOPYRAN ANTITUBERCULAR AGENTS, IN MICE(POSTER SESSION 15-F)(ABSTRACT F-27) |
37TH ICAAC ABSTRACTS |
37 |
150(ABSTR F-27) |
1997 |
|
| |
| BAKER, WR; KEELER, EL; CAI, S; TOWELL, JA; PASTOR, DR; MORGENROTH, JN; ANDERSON, SW; ARAIN, TM |
IDENTIFICATION OF PA-824, A NOVEL 6-NITROIMIDAZOPYRAN ANTITUBERCULAR AGENT, USING HIGH THROUGHPUT SYNTHESIS AND SCREENING METHODOLOGY(SESSION 84 ABSTRACT F214) |
36TH ICAAC ABSTRACTS |
36 |
137(ABSTR F214) |
1996 |
|
| |
| VANDEVANTER, DR; WARRENER, P; HICKEY, MJ; STOVER, CK; SHERMAN, DR |
MECHANISM OF ACTION OF PA-824, A NEW NITROIMIDAZOPYRAN WITH ACTIVITY AGAINST MYCOBACTERIUM TUBERCULOSIS(SESSION 144 ABSTRACT C142) |
36TH ICAAC ABSTRACTS |
36 |
59(ABSTR C142) |
1996 |
|
| |
| ARAIN, TM; LANGHORNE, MH; RODRIGUEZ, JL; MORGENROTH, JN; BAKER, WR; STOVER, CK |
RAPID ASSESSMENT OF IN VIVO ACTIVITY OF NITROIMIDAZOPYRAN (NAP) COMPOUNDS AGAINST MYCOBACTERIUM TUBERCULOSIS USING A REPORTER STRAIN STRATEGY(SESSION 84 ABSTRACT F213) |
36TH ICAAC ABSTRACTS |
36 |
137(ABSTR F213) |
1996 |
|
| |
| HUMBLE, DJ; SHAWAR, RM; VAN DALFSEN, JM; KREISWIRTH, BN; MOGHAZEH, SL; KUREPINA, NE; BAKER, WR; ARAIN, TM |
NITROIMIDAZOPYRAN (NAP)COMPOUNDS: IN VITRO SPECTRUM OF ACTIVITY, INCLUDING ACTIVITY AGAINST DRUG-SENSITIVE AND MULTIDRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS(SESSION 84 ABSTRACT F212) |
36TH ICAAC ABSTRACTS |
36 |
137(ABSTR F212) |
1996 |
|
| |
| ARAIN, TM; MORGENROTH, JN; ANDERSON, SW; VAN DALFSEN, JM; HUMBLE, DJ; RODRIGUEZ, JL; SHAWAR, RM; BAKER, WR; STOVER, CK |
CHARACTERIZATION OF THE IN VITRO ACTIVITY OF THE NITROIMIDAZOPYRAN COMPOUND PA-824 AGAINST MYCOBACTERIUM SPP USING REPORTER STRAINS(SESSION 84 ABSTRACT F215) |
36TH ICAAC ABSTRACTS |
36 |
137(ABSTR F215) |
1996 |
|
| |
| LILLIBRIDGE, JH; NYWALL, CS; SHAWAR, RM; SLATTERY, JT |
PA-824, A NITOIMIDAZOPYRAN ANTITUBERCULAR AGENT: FAVORABLE PHARMACOKINETIC PARAMETERS IN MICE AFTER DELIVERY IN A NOVEL ORAL FORMULATION(SESSION 84 ABSTRACT F216) |
36TH ICAAC ABSTRACTS |
36 |
137(ABSTR F216) |
1996 |
|
| |
Medline Abstract