Organism

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Organism

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Chemical Name: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-			Synonyms Tazobactam CL298741 YTR830H		AIDS# 010826
					Links to ChemID Plus by CAS# 89786-04-989785-84-2 [SODIUM SALT]
					Links to PubChem by AIDS# 010826
SODIUM SALT
C10 H12 N4 O5 S		MW: 300.29			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 8	PHIA (Flexible Bonds): 2.7	Calc. LogP (MDL QSAR): 0.25
Company:			Calc. LogP (KowWin): -1.72
Anti-HIV Cellular data: 0	Anti-HIV Enzyme data: 0	Lines of Data: 6	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 0	Number of References: 3	Lipinski: 4 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; .BETA.-LACTAMASE INHIBITORS; PENICILLINS; ANTIMYCOBACTERIALS

Chemical Name: Clavulinic Acid			Synonyms Clavulanate		AIDS# 044773
					Links to ChemID Plus by CAS#
					Links to PubChem by AIDS# 044773
POTASSIUM SALT
C8 H9 N O5		MW: 199.16			Links to PubMed by CAS#
H-bond donors: 2	H-bond acceptors: 6	PHIA (Flexible Bonds): 2.2	Calc. LogP (MDL QSAR): -1.61
Company:			Calc. LogP (KowWin): -2.04
Anti-HIV Cellular data: 0	Anti-HIV Enzyme data: 0	Lines of Data: 22	TB Min MIC 128 ug/mL	TB Min IC50 0.5 ug/mL	Links to NIST by AIDS#
Number of References: 0	Number of References: 0	Number of References: 7	Lipinski: 4 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; .BETA.-LACTAMASE INHIBITORS; .BETA.-LACTAMS; AMINO ACIDS; ANTIMYCOBACTERIALS

Chemical Name: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-,4,4-dioxide, (2S, cis)			Synonyms Sulbactam		AIDS# 044774
					Links to ChemID Plus by CAS# 68373-14-8
					Links to PubChem by AIDS# 044774

C8 H11 N O5 S		MW: 233.24			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 6	PHIA (Flexible Bonds): 1.9	Calc. LogP (MDL QSAR): 0.14
Company: PFIZER			Calc. LogP (KowWin): 0.5
Anti-HIV Cellular data: 0	Anti-HIV Enzyme data: 0	Lines of Data: 17	TB Min MIC > 16 ug/mL	TB Min IC50 0.4 ug/mL	Links to NIST by AIDS#
Number of References: 0	Number of References: 0	Number of References: 4	Lipinski: 4 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; .BETA.-LACTAMASE INHIBITORS; PENICILLINS; ANTIMYCOBACTERIALS

Chemical Name: 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-((1-methyl-1H-1,2,3-triazol-4-yl)methylene)-7-oxo-, sodium salt, (R-(Z))-			Synonyms BRL 42715 BRL-42715 C6-(N1-Methyl-1, 2, 3-trazolylmethylene)penem		AIDS# 070039
					Links to ChemID Plus by CAS# 102209-75-6
					Links to PubChem by AIDS# 070039
Z
C10 H9 N4 O3 S . Na		MW: 288.26			Links to PubMed by CAS#
H-bond donors: 0	H-bond acceptors: 8	PHIA (Flexible Bonds): 4.29	Calc. LogP (MDL QSAR): 4.65
Company:			Calc. LogP (KowWin):
Anti-HIV Cellular data: 0	Anti-HIV Enzyme data: 0	Lines of Data: 2	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 0	Number of References: 1	Lipinski: (Score, out of 4)
Classes: .BETA.-LACTAMASE INHIBITORS; PENICILLINS

Chemical Name: 3-Thiotridecanamide			Synonyms 3-Thiotridecanamide		AIDS# 094388
					Links to ChemID Plus by CAS#
					Links to PubChem by AIDS# 094388

C12 H25 N O S		MW: 231.4			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 3	PHIA (Flexible Bonds): 12.04	Calc. LogP (MDL QSAR): 4.1
Company:			Calc. LogP (KowWin): 3.99
Anti-HIV Cellular data: 0	Anti-HIV Enzyme data: 0	Lines of Data: 1	TB Min MIC > 25 ug/mL	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 0	Number of References: 1	Lipinski: 4 (Score, out of 4)
Classes: .BETA.-LACTAMASE INHIBITORS; AMIDES

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