Organism

252 Record(s) returned from your Search Criteria

Organism

NIAID Home / Chemical/Therapeutic Class Search / Chemical/Therapeutic Class Results

Page: 1 2 3 4 5 6 7 8 9 10 Next Last (10 records per page)

Chemical Name: 7',10,11-Trimethoxyemetan-6'-ol			Synonyms Cephaelinel Isoquinoline alkaloid Cephaeline NSC32944 (DIHYDROCHLORIDE)		AIDS# 002677
					Links to ChemID Plus by CAS# 483-17-05853-29-2 [DIHYDROCHLORIDE]
					Links to PubChem by AIDS# 002677
ISOLATED FROM URAGOGA IPECACUANHA; OR DIHYDROCHLORIDE SALT; OR DIHYDROCHLORIDE, HEPTAHYDRATE
C28 H38 N2 O4		MW: 466.62			Links to PubMed by CAS#
H-bond donors: 2	H-bond acceptors: 6	PHIA (Flexible Bonds): 7.07	Calc. LogP (MDL QSAR): 4.86
Company:			Calc. LogP (KowWin): 4.89
Lines of Data: 1	Lines of Data: 4	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 3	Number of References: 0	Lipinski: 4 (Score, out of 4)
Classes: NON-NUCLEOSIDE RT INHIBITORS; ALKALOIDS; NATURAL PRODUCTS, PLANT; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 6',7',10,11-Tetramethoxyemetan			Synonyms Isoquinoline alkaloid Emetine 6', 7', 10, 11-Tetramethoxyemetan Cephaeline methyl ether NSC33669 (HYDROCHLORIDE)		AIDS# 002678
					Links to ChemID Plus by CAS# 483-18-1 [FREE BASE] 316-42-7 [DIHYDROCHLORIDE]
					Links to PubChem by AIDS# 002678
ISOLATED FROM URAGOGA IPECACUANHA; HYDROCHLORIDE SALT; OR DIHYDROCHLORIDE SALT
C29 H40 N2 O4		MW: 480.65			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 6	PHIA (Flexible Bonds): 7.58	Calc. LogP (MDL QSAR): 5.62
Company:			Calc. LogP (KowWin): 5.2
Lines of Data: 2	Lines of Data: 4	Lines of Data: 1	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 3	Number of References: 1	Lipinski: 3 (Score, out of 4)
Classes: NON-NUCLEOSIDE RT INHIBITORS; ALKALOIDS; NATURAL PRODUCTS, PLANT; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 4H-Dibenzo[de,g]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)-			Synonyms 4H-Dibenzo(de, g)quinoline, 9-(4, 5-dimethoxy-2-((1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5, 6, 6a, 7-tetrahydro-1, 2, 10-trimethoxy-6-methyl-, (S-(R, R))- Thalicarpine Isoquinoline alkaloid NSC68075		AIDS# 002681
					Links to ChemID Plus by CAS# 5373-42-2
					Links to PubChem by AIDS# 002681

C41 H48 N2 O8		MW: 696.84			Links to PubMed by CAS#
H-bond donors: 0	H-bond acceptors: 10	PHIA (Flexible Bonds): 10.44	Calc. LogP (MDL QSAR): 6.09
Company:			Calc. LogP (KowWin): 5.54
Lines of Data: 1	Lines of Data: 1	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 1	Number of References: 0	Lipinski: 2 (Score, out of 4)
Classes: ALKALOIDS; NATURAL PRODUCTS, PLANT; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 5,5'-(1,1'-Dihydroxy-8,8'-dimethoxy-6-6'-dimethyl[2,2'-binaphthalene]-4,4'-diyl)bis[1,2,3,4-tetrahydro-1,3-dimethyl-6,8-isoquinolinediol], (1R,3R,5S,1'R,3'R,5'S)			Synonyms Michellamine A (-)-Michellamine A NSC650898		AIDS# 003609
					Links to ChemID Plus by CAS# 137793-81-8
					Links to PubChem by AIDS# 003609
(-)
C46 H48 N2 O8		MW: 756.89			Links to PubMed by CAS#
H-bond donors: 8	H-bond acceptors: 10	PHIA (Flexible Bonds): 9.66	Calc. LogP (MDL QSAR): 1.7
Company:			Calc. LogP (KowWin): 9.19
Lines of Data: 7	Anti-HIV Enzyme data: 0	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 4	Number of References: 0	Number of References: 0	Lipinski: 2 (Score, out of 4)
Classes: NATURAL PRODUCTS, PLANT; BINAPHTHALENES; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 5,5'-(1,1'-Dihydroxy-8-8'-dimethoxy-6,6'-dimethyl[2,2'-binaphthalene]-4,4'-diyl)bis[1,2,3,4-tetrahydro-1,3-dimethyl-6,8-isoquinolinediol], (1R,3R,5R,1'R,3'R,5'S)			Synonyms Michellamine B (-)-Michellamine B NSC649324 (FREE BASE); NSC661755 (DIACETATE SALT)		AIDS# 003610
					Links to ChemID Plus by CAS# 137893-48-2 [FREE BASE]
					Links to PubChem by AIDS# 003610
ISOLATED FROM ANCISTROCLADUS ABBREVIATUS; (-); M,P ORIENTATION ON TERMINAL RINGS; OR DIACETATE SALT
C46 H48 N2 O8		MW: 756.89			Links to PubMed by CAS#
H-bond donors: 8	H-bond acceptors: 10	PHIA (Flexible Bonds): 9.66	Calc. LogP (MDL QSAR): 1.7
Company:			Calc. LogP (KowWin): 9.19
Lines of Data: 40	Lines of Data: 2	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 6	Number of References: 1	Number of References: 0	Lipinski: 2 (Score, out of 4)
Classes: NATURAL PRODUCTS, PLANT; BINAPHTHALENES; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 2,3-Didehydro-6',7',10,11-tetramethoxyemetan			Synonyms Dehydroemetine Ipecac alkaloid		AIDS# 003623
					Links to ChemID Plus by CAS# 4914-30-1
					Links to PubChem by AIDS# 003623
(-)
C29 H38 N2 O4		MW: 478.63			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 6	PHIA (Flexible Bonds): 7.39	Calc. LogP (MDL QSAR): 5.2
Company:			Calc. LogP (KowWin): 5.24
Anti-HIV Cellular data: 0	Lines of Data: 3	Lines of Data: 2	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 2	Number of References: 1	Lipinski: 3 (Score, out of 4)
Classes: SEMI-SYNTHETICS; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: alpha.-[[(1,1-Dimethylethyl)sulfonyl]methyl]-N-[1-[[[2-hydroxy-3-[1-(trifluoromethyl)-1,2,3,4-tetrahydro-2-isoquinolinyl]-1-(phenylmethyl)propyl]amino]carbonyl]-2-methylpropyl]-1-naphthalenepropanamid			Synonyms HOEtNH2 isostere CF3-isoquinol der.		AIDS# 005149
					Links to ChemID Plus by CAS#
					Links to PubChem by AIDS# 005149

C43 H52 F3 N3 O5 S		MW: 779.96			Links to PubMed by CAS#
H-bond donors: 3	H-bond acceptors: 11	PHIA (Flexible Bonds): 13.4	Calc. LogP (MDL QSAR): 7.03
Company: BAYER AG			Calc. LogP (KowWin): 6.55
Lines of Data: 1	Lines of Data: 1	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS# 005149
Number of References: 1	Number of References: 1	Number of References: 0	Lipinski: 1 (Score, out of 4)
Classes: PEPTIDOMIMETICS, HYDROXYETHYLAMINE; HIV PROTEASE INHIBITORS; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 5,5-(1,1'-Dihydroxy-8-8'-dimethoxy-6,6'-dimethyl[2,2'-binaphthalene-4,4'-diyl)bis[1,2,3,4-tetrahydro-1,3-dimethyl-6,8-isoquinolinediol], (1R,3R,5R,1'R,3'R,5'R)			Synonyms Michellamine C		AIDS# 005324
					Links to ChemID Plus by CAS# 143168-23-4
					Links to PubChem by AIDS# 005324
M,M (TERMINAL RING ORIENTATION)
C46 H48 N2 O8		MW: 756.89			Links to PubMed by CAS#
H-bond donors: 8	H-bond acceptors: 10	PHIA (Flexible Bonds): 9.66	Calc. LogP (MDL QSAR): 1.7
Company:			Calc. LogP (KowWin): 9.19
Lines of Data: 2	Anti-HIV Enzyme data: 0	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 0	Number of References: 0	Lipinski: 2 (Score, out of 4)
Classes: NATURAL PRODUCTS; BINAPHTHALENES; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: 2,4-Diamino-5-[4-chloro-3-(tetrahydroisoquinoline-2-ylazo)phenyl]-6-ethylpyrimidine			Synonyms		AIDS# 007515
					Links to ChemID Plus by CAS#
					Links to PubChem by AIDS# 007515

C21 H22 Cl N7		MW: 407.91			Links to PubMed by CAS#
H-bond donors: 2	H-bond acceptors: 8	PHIA (Flexible Bonds): 5.64	Calc. LogP (MDL QSAR): 2.36
Company: ASTON MOLECULES LTD.			Calc. LogP (KowWin): 4.74
Anti-HIV Cellular data: 0	Anti-HIV Enzyme data: 0	Lines of Data: 2	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 0	Number of References: 1	Lipinski: 4 (Score, out of 4)
Classes: DIHYDROFOLATE REDUCTASE (DHFR) INHIBITORS; 1,2,3,4-TETRAHYDROISOQUINOLINES

Chemical Name: Carbamic acid, [(1S)-2-[(1R)-1-[[(2R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl]-1-(1H-indol-3-ylmethyl)-2-oxoethyl]-, 1,1-dimethylethyl ester			Synonyms Emetine der. NSC109350		AIDS# 011190
					Links to ChemID Plus by CAS#
					Links to PubChem by AIDS# 011190

C45 H58 N4 O7		MW: 766.97			Links to PubMed by CAS#
H-bond donors: 2	H-bond acceptors: 10	PHIA (Flexible Bonds): 12.37	Calc. LogP (MDL QSAR): 5.07
Company:			Calc. LogP (KowWin): 7.78
Lines of Data: 1	Anti-HIV Enzyme data: 0	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 0	Number of References: 0	Lipinski: 2 (Score, out of 4)
Classes: INDOLES; 1,2,3,4-TETRAHYDROISOQUINOLINES

Page: 1 2 3 4 5 6 7 8 9 10 Next Last (10 records per page)

NIAID Home / Chemical/Therapeutic Class Search / Chemical/Therapeutic Class Results