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Organism

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Chemical Name: Nystatin			Synonyms Nystatin Nystatin A Nystatin A1 Mycostatin Fungicidin Diastatin Nilstat Nystex Stamycin Moronal Biofanal NSC150817		AIDS# 004993
					Links to ChemID Plus by CAS# 1400-61-9
					Links to PubChem by AIDS# 004993
ISOLATED FROM STREPTOMYCES NOURSEI AND S. AUREUS; MIXTURE OF 3 ACTIVE POLYENES, NYSTATIN A1 DRAWN
C47 H75 N O17		MW: 926.1			Links to PubMed by CAS#
H-bond donors: 12	H-bond acceptors: 18	PHIA (Flexible Bonds): 24.17	Calc. LogP (MDL QSAR): 1.97
Company: WYETH-AYERST; APOTHECAN; SAVAGE			Calc. LogP (KowWin): -3.33
Lines of Data: 5	Anti-HIV Enzyme data: 0	Lines of Data: 54	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 2	Number of References: 0	Number of References: 16	Lipinski: 1 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; ANTIFUNGALS; AMINOGLYCOSIDES; NATURAL PRODUCTS; POLYENES; ANTIBIOTICS; MACROLIDES, POLYENE; AMPHOTERICIN B ANALOGS; MYCINS

Chemical Name: 2-Deoxy-4-O-(2,6-diamine-2,6-dideoxy-.alpha.-D-glucopyranosyl)-D-streptamine			Synonyms Neamine Neomycin A Dekamycin V Neamin Nebramycin X Negamicin		AIDS# 005080
					Links to ChemID Plus by CAS# 3947-65-7
					Links to PubChem by AIDS# 005080
ISOLATED FROM STREPTOMYCES FRADIAE
C12 H26 N4 O6		MW: 322.36			Links to PubMed by CAS#
H-bond donors: 8	H-bond acceptors: 10	PHIA (Flexible Bonds): 5.72	Calc. LogP (MDL QSAR): -3.76
Company: MERCK			Calc. LogP (KowWin): -7.07
Lines of Data: 2	Lines of Data: 14	Lines of Data: 1	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 2	Number of References: 9	Number of References: 1	Lipinski: 3 (Score, out of 4)
Classes: NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES; REV-RRE INHIBITORS; MYCINS

Chemical Name: O-2,6-Diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)-O-[.beta.-D-ribofuranosyl-(1->5)]-2-deoxy-D-streptamine			Synonyms Ribostamycin Hetangmycin Vistamycin Xylostatin NSC138925 (FREE BASE)		AIDS# 005081
					Links to ChemID Plus by CAS# 25546-65-0 [FREE BASE]
					Links to PubChem by AIDS# 005081
ISOLATED FROM STREPTOMYCES RIBOSIDIFICUS; OR MONOSULFATE SALT
C17 H34 N4 O10		MW: 454.47			Links to PubMed by CAS#
H-bond donors: 10	H-bond acceptors: 14	PHIA (Flexible Bonds): 8.21	Calc. LogP (MDL QSAR): -3.65
Company: MEIJI			Calc. LogP (KowWin): -8.05
Lines of Data: 1	Lines of Data: 2	Lines of Data: 13	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 2	Number of References: 2	Lipinski: 2 (Score, out of 4)
Classes: REV-TAT INHIBITORS; POLYSACCHARIDES; NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES; MYCINS; ANTIMYCOBACTERIALS

Chemical Name: D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-xylofuranosyl-(1-5))-N(sup 1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-			Synonyms Butirosin Butirosin A Ambutyrosin		AIDS# 005082
					Links to ChemID Plus by CAS# 12772-35-9 [FREE BASE] 51022-98-1 [DISULFATE]
					Links to PubChem by AIDS# 005082
ISOLATED FROM BACILLUS CIRCULANS; OR DISULFATE SALT
C21 H41 N5 O12		MW: 555.58			Links to PubMed by CAS#
H-bond donors: 12	H-bond acceptors: 17	PHIA (Flexible Bonds): 11.29	Calc. LogP (MDL QSAR): -4.39
Company: PARKE-DAVIS			Calc. LogP (KowWin): -10.13
Anti-HIV Cellular data: 0	Lines of Data: 1	Lines of Data: 1	TB Min MIC 1.6 ug/mL	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 1	Number of References: 1	Lipinski: 1 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES

Chemical Name: D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy			Synonyms Neomycin B Sulfate Neomycin Sulfate Neobrettin Neomas Neomycane CCRIS 5462 Caswell No. 595 Fradiomycin Fradiomycinum Framycetin HSDB 3242 Mycifradin Soframycin USAF CB-19 NSC156885 (SULFATE); NSC47151(SULFATE)		AIDS# 005083
					Links to ChemID Plus by CAS# 1404-04-2 [FREE BASE] 1405-10-3 [SULFATE]
					Links to PubChem by AIDS# 005083
MAJOR COMPONENT OF NEOMYCIN; ISOLATED FROM STREPTOMYCES FRADIAE; TRISULFATE SALT; OR MONOSULFATE SALT
C23 H46 N6 O13		MW: 614.65			Links to PubMed by CAS#
H-bond donors: 13	H-bond acceptors: 19	PHIA (Flexible Bonds): 11.47	Calc. LogP (MDL QSAR): -2.77
Company: PARKE-DAVIS; UPJOHN; MERCK; SIGMA			Calc. LogP (KowWin): -9.41
Lines of Data: 5	Lines of Data: 28	Lines of Data: 48	TB Min MIC 0.29 ug/mL	TB Min IC50	Links to NIST by AIDS#
Number of References: 4	Number of References: 12	Number of References: 9	Lipinski: 1 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; NATURAL PRODUCTS; ANTIBIOTICS; POLYSACCHARIDES; AMINOGLYCOSIDES; RNA BINDING AGENTS; REV-TAT INHIBITORS; REV-RRE INHIBITORS; TAT INHIBITORS; MYCINS; ANTIMYCOBACTERIALS

Chemical Name: O-2-Amino-2-deoxy-.alpha.-D-glucopyranosyl-(1->4)-O-[O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1->3)-.beta.D-ribofuranosyl(1->5)]-2-deoxy-D-streptamine			Synonyms Paromomycin Paramomycin Sulfate Aminosidine, sulfate Hydroxymycin sulfate Paromomycin sulfate Rx346208 Humatin NSC227228 (SULFATE)		AIDS# 005084
					Links to ChemID Plus by CAS# 1263-89-4 [SULFATE] 7542-37-2 [FREE BASE]
					Links to PubChem by AIDS# 005084
ISOLATED FROM STREPTOMYCES RIMOSUS; OR SULFATE SALT
C23 H45 N5 O14		MW: 615.63			Links to PubMed by CAS#
H-bond donors: 13	H-bond acceptors: 19	PHIA (Flexible Bonds): 11.47	Calc. LogP (MDL QSAR): -2.83
Company: PARKE-DAVIS			Calc. LogP (KowWin): -9.29
Lines of Data: 1	Lines of Data: 7	Lines of Data: 241	TB Min MIC < 0.09 ug/mL	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 4	Number of References: 32	Lipinski: 1 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; AMINOGLYCOSIDES; NATURAL PRODUCTS; ANTIBIOTICS; GLYCOSIDES; MYCINS; ANTIMYCOBACTERIALS

Chemical Name: Lividomycin			Synonyms Lividomycin A		AIDS# 005085
					Links to ChemID Plus by CAS# 36441-41-5
					Links to PubChem by AIDS# 005085
ISOLATED FROM STREPTOMYCES LIVIDUS; OR MONOSULFATE SALT
C29 H55 N5 O18		MW: 761.77			Links to PubMed by CAS#
H-bond donors: 15	H-bond acceptors: 23	PHIA (Flexible Bonds): 14.54	Calc. LogP (MDL QSAR): -2.1
Company:			Calc. LogP (KowWin): -9.18
Anti-HIV Cellular data: 0	Lines of Data: 1	Lines of Data: 52	TB Min MIC 50 ug/mL	TB Min IC50 -50 25 ug/mL	Links to NIST by AIDS#
Number of References: 0	Number of References: 1	Number of References: 3	Lipinski: 1 (Score, out of 4)
Classes: NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES; MYCINS; ANTIMYCOBACTERIALS

Chemical Name: O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[6-amino-6-deoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy-D-streptamine			Synonyms Kanamycin Kanamycin A KM Kantrex (1:1 sulfate) Klebcil (1:1 sulfate) KAN		AIDS# 005086
					Links to ChemID Plus by CAS# 8063-07-825389-94-0 [KANAMYCIN A,1:1 SULFATE] 59-01-8 [KANAMYCIN A]
					Links to PubChem by AIDS# 005086
ISOLATED FROM STREPTOMYCES KANAMYCETICUS; KANAMYCIN IS A MIXTURE OF KANAMYCINS A, B, C; KANAMYCIN A (AS DRAWN) IS THE MAJOR COMPONENT; OR MONOSULFATE SALT
C18 H36 N4 O11		MW: 484.5			Links to PubMed by CAS#
H-bond donors: 11	H-bond acceptors: 15	PHIA (Flexible Bonds): 8.99	Calc. LogP (MDL QSAR): -3.51
Company: SMITHKLINE BEECHAM; BRISTOL-MYERS; APOTHECON			Calc. LogP (KowWin): -6.7
Lines of Data: 1	Lines of Data: 9	Lines of Data: 345	TB Min MIC 0.63 ug/mL	TB Min IC50 2.5 ug/mL	Links to NIST by AIDS#
Number of References: 1	Number of References: 4	Number of References: 51	Lipinski: 2 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES; ANTIBACTERIALS; KANAMYCINS; REV-RRE INHIBITORS; OLIGOSACCHARIDES; MYCINS; ANTIMYCOBACTERIALS

Chemical Name: Kanamycin B			Synonyms Kanamycin B Aminodeoxykanamycin Bekanamycin NK 1006 NK-1006		AIDS# 005087
					Links to ChemID Plus by CAS# 4696-76-8
					Links to PubChem by AIDS# 005087
ISOLATED FROM STREPTOMYCES KANAMYCETICUS; OR MONOSULFATE SALT
C18 H37 N5 O10		MW: 483.52			Links to PubMed by CAS#
H-bond donors: 11	H-bond acceptors: 15	PHIA (Flexible Bonds): 8.99	Calc. LogP (MDL QSAR): -3.44
Company:			Calc. LogP (KowWin): -7.3
Anti-HIV Cellular data: 0	Lines of Data: 7	Lines of Data: 14	TB Min MIC 2 ug/mL	TB Min IC50	Links to NIST by AIDS#
Number of References: 0	Number of References: 3	Number of References: 2	Lipinski: 2 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES; ANTIBACTERIALS; KANAMYCINS; OLIGOSACCHARIDES; MYCINS; ANTIMYCOBACTERIALS

Chemical Name: D-Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribohexopyranosyl-(1->4)]-2-deoxy-			Synonyms Tobramycin Tobrex Nebcin (Sulfate)		AIDS# 005088
					Links to ChemID Plus by CAS# 32986-56-479645-27-5 [2:5 SULFATE SALT]
					Links to PubChem by AIDS# 005088
ISOLATED FROM STREPTOMYCES TENEBRARIUS; SULFATE SALT (2:5)
C18 H37 N5 O9		MW: 467.52			Links to PubMed by CAS#
H-bond donors: 10	H-bond acceptors: 14	PHIA (Flexible Bonds): 8.79	Calc. LogP (MDL QSAR): -3.19
Company: LILLY; ASTRA ; ALCON			Calc. LogP (KowWin): -5.76
Lines of Data: 2	Lines of Data: 12	Lines of Data: 78	TB Min MIC 4 ug/mL	TB Min IC50	Links to NIST by AIDS#
Number of References: 2	Number of References: 4	Number of References: 8	Lipinski: 2 (Score, out of 4)
Classes: ANTITUBERCULOUS AGENTS; NATURAL PRODUCTS; ANTIBIOTICS; AMINOGLYCOSIDES; REV-RRE INHIBITORS; MYCINS; ANTIMYCOBACTERIALS

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