Organism

Chemical Name: Carbamic acid, (chloroacetyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester			Synonyms O-(Chloroacetylcarbamoyl)fumagillol TNP-470 Agm 1470		AIDS# 042739
					Links to ChemID Plus by CAS# 129298-91-5
					Links to PubChem by AIDS# 042739

C19 H28 Cl N O6		MW: 401.88			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 8	PHIA (Flexible Bonds): 6.11	Calc. LogP (MDL QSAR): 3.08
Company: TAKEDA			Calc. LogP (KowWin): 2.6
Lines of Data: 3	Anti-HIV Enzyme data: 0	Lines of Data: 23	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 3	Number of References: 0	Number of References: 6	Lipinski: 4 (Score, out of 4)
Classes: ANTIANGIOGENICS

Chemical Name: 1-Oxaspiro(2,5)octan-6-one, 4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-4-hydroxy-5-methoxy-, (1S,2R,3S,4R,5S)-(-)-			Synonyms Ovalicin SL-1846 Graphinone		AIDS# 042740
					Links to ChemID Plus by CAS# 19683-98-8
					Links to PubChem by AIDS# 042740

C16 H24 O4		MW: 280.36			Links to PubMed by CAS#
H-bond donors: 0	H-bond acceptors: 4	PHIA (Flexible Bonds): 3.31	Calc. LogP (MDL QSAR): 3.22
Company: NOVARTIS			Calc. LogP (KowWin): 1.94
Lines of Data: 1	Anti-HIV Enzyme data: 0	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 0	Number of References: 0	Lipinski: 4 (Score, out of 4)
Classes: ANTIANGIOGENICS

Chemical Name: Butanediamide, N4-hydroxy-N1-(2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl)-2-(2-methylpropyl)-3-((2-thienylthio)methyl)-, (2R-(1(S),2R,3S*))-			Synonyms BB94, BB-94 Batimastat		AIDS# 043101
					Links to ChemID Plus by CAS# 130370-60-4
					Links to PubChem by AIDS# 043101

C23 H31 N3 O4 S2		MW: 477.65			Links to PubMed by CAS#
H-bond donors: 4	H-bond acceptors: 9	PHIA (Flexible Bonds): 11.36	Calc. LogP (MDL QSAR): 1.51
Company: BRITISH BIOTECHNOLOGY LTD			Calc. LogP (KowWin): 2.79
Lines of Data: 3	Anti-HIV Enzyme data: 0	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 0	Number of References: 0	Lipinski: 4 (Score, out of 4)
Classes: PEPTIDOMIMETICS; ANTINEOPLASTICS; MATRIX METALLOPROTEINASE INHIBITORS (MMPI); ANTIANGIOGENICS; HYDROXAMATES

Chemical Name: 3-Thiomorpholinecarboxamide, N-hydroxy-2,2-dimethyl-4-[[4-(4-pyridinyloxy)phenyl]sulfonyl]-, (3S)-			Synonyms Prinomastat AG3340 AG 3340		AIDS# 045699
					Links to ChemID Plus by CAS#
					Links to PubChem by AIDS# 045699

C18 H21 N3 O5 S2		MW: 423.51			Links to PubMed by CAS#
H-bond donors: 2	H-bond acceptors: 9	PHIA (Flexible Bonds): 6.18	Calc. LogP (MDL QSAR): 2.59
Company: AGOURON			Calc. LogP (KowWin): 1.06
Lines of Data: 3	Anti-HIV Enzyme data: 0	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 1	Number of References: 0	Number of References: 0	Lipinski: 4 (Score, out of 4)
Classes: PEPTIDOMIMETICS; ANTINEOPLASTICS; MATRIX METALLOPROTEINASE INHIBITORS (MMPI); ANTIANGIOGENICS; HYDROXAMATES