Opportunistic Infections  Citation List: 

June  10, 2009 – June  23, 2009

TB (Tuberculosis, Mycobacterium, Avium, Drug Resistant, MAC, MDR)

1. Dihydrophthalazine Antifolates, a Novel Family of Antibacterial Drugs: In Vitro and in Vivo Properties.

Caspers P, Bury L, Gaucher B, Heim J, Shapiro S, Siegrist S, Schmitt-Hoffmann A, Thenoz L, Urwyler H.

Antimicrob Agents Chemother. 2009 Jun 22. [Epub ahead of print]

PMID: 19546364 [PubMed - as supplied by publisher]    

2. Discovery and Development of the Covalent Hydrates of Trifluoromethylated Pyrazoles as Riboflavin Synthase Inhibitors with Antibiotic Activity Against Mycobacterium tuberculosis.

Zhao Y, Bacher A, Illarionov B, Fischer M, Georg G, Ye QZ, Fanwick PE, Franzblau SG, Wan B, Cushman M.

J Org Chem. 2009 Jun 22. [Epub ahead of print]

PMID: 19545132 [PubMed - as supplied by publisher]

3. Synthetic Lipopeptide MALP-2 Inhibits Intracellular Growth of Mycobacterium bovis BCG in Alveolar Macrophages-Preliminary Data.

Jörgens G, Bange FC, Mühlradt PF, Pabst R, Maus UA, Tschernig T.

Inflammation. 2009 Jun 19. [Epub ahead of print]

PMID: 19543820 [PubMed - as supplied by publisher]    

4. Preparation and in-vitro Evaluation of 4-Benzylsulfanylpyridine-2-carbohydrazides as Potential Antituberculosis Agents.

Herzigová P, Klimešová V, Palát K, Kaustová J, Dahse HM, Möllmann U.

Arch Pharm (Weinheim). 2009 Jun 17. [Epub ahead of print]

PMID: 19536781 [PubMed - as supplied by publisher]                

5. Dequalinium, a Novel Inhibitor of Mycobacterium tuberculosis Mycothiol Ligase Identified by High-Throughput Screening.

Gutierrez-Lugo MT, Baker H, Shiloach J, Boshoff H, Bewley CA.

J Biomol Screen. 2009 Jun 12. [Epub ahead of print]

PMID: 19525487 [PubMed - as supplied by publisher]

6. Synthesis and antimycobacterial activity of 5-formylaminopyrimidines; analogs of antibacterial purines.

Braendvang M, Charnock C, Gundersen LL.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3297-9. Epub 2009 Apr 23.

PMID: 19427200 [PubMed - in process]

7. Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.

Zhang Z, Caradoc-Davies TT, Dickson JM, Baker EN, Squire CJ.

J Mol Biol. 2009 Jun 19;389(4):722-33. Epub 2009 Apr 24.          

PMID: 19394344 [PubMed - in process]

Antimicrobials, Antifungals (General)

8. Synthesis, Antibacterial and Antifungal Activities of Novel 1,2,4-Triazolium Derivatives.

Luo Y, Lu YH, Gan LL, Zhou CH, Wu J, Geng RX, Zhang YY.

Arch Pharm (Weinheim). 2009 Jun 19. [Epub ahead of print]

PMID: 19544478 [PubMed - as supplied by publisher]    

9. The In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent.

Schaadt R, Sweeney D, Shinabarger D, Zurenko G.

Antimicrob Agents Chemother. 2009 Jun 15. [Epub ahead of print]

PMID: 19528279 [PubMed - as supplied by publisher]    

10. Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approaches.

Mochalkin I, Miller JR, Narasimhan L, Thanabal V, Erdman P, Cox PB, Prasad JV, Lightle S, Huband MD, Stover CK.

ACS Chem Biol. 2009 Jun 19;4(6):473-83.

PMID: 19413326 [PubMed - in process]            

Citations from the ISI Web of  Knowledge Listings for  O.I.

11. Kulkarni, A, et al.

Synthesis, characterization, DNA cleavage and in vitro antimicrobial studies of La(III), Th(IV) and VO(IV) complexes with Schiff bases of coumarin derivatives
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  2009 (July) 44: 2904 – 2912                        

12. Tandon, VK, et al.

Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  2009 (August) 44: 3130 – 3137

13. Fassihi, A, et al.            

Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2,6-dimethyl-N-3,N-5-bisaryl-1,4-dihydropyridine-3,5-dicarbox amides
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2009 (August) 44: 3253 – 3258