ONLINE DATABASE SEARCH - DMDI-LS-139-MEMO
1. 60255 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Pyrrolidine derivatives as immunomodulators and antiviral agents
Nash, Robert James, Carroll, Miles William, Watson, Alison Ann, Fleet, George William John, and Horne, Graeme
PATENT: WO 2007010266 ISSUE DATE: 20070125
APPLICATION: 2006 PP: 72pp.
ASSIGNEE: (MNL Pharma Limited, UK
2. 60256 DMID-LS-139; PUBMED-DMID-2/26/2007
Dysoxylins A-D, Tetranortriterpenoids with Potent Anti-RSV Activity from Dysoxylum gaudichaudianum
Chen, JL, Kernan, MR, Jolad, SD, Stoddart, CA, Bogan, M, and Cooper, R
J Nat Prod 2007. 70(2): 312-5
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17315968&dopt=abstract
3. 60257 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Synthetic single strand deoxynucleosides for antiviral uses
Wang, Li-Ying, Bao, Mu-Sheng, and Yu, Yong-Li
PATENT: WO 2007012285 ISSUE DATE: 20070201
APPLICATION: 2006 PP: 62pp.
ASSIGNEE: (Changchun Huapu Biotechnology Co., Ltd. Peop. Rep. China
4. 60258 DMID-LS-139; PUBMED-DMID-2/26/2007
Molecular diagnostics of hepatitis C virus infection: a systematic review
Scott, JD and Gretch, DR
JAMA 2007. 297(7): 724-32
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17312292&dopt=abstract
5. 60259 DMID-LS-139; PUBMED-DMID-2/26/2007
Proteases essential for human influenza virus entry into cells and their inhibitors as potential therapeutic agents
Kido, H, Okumura, Y, Yamada, H, Le, TQ, and Yano, M
Curr Pharm Des 2007. 13(3): 403-12
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17311557&dopt=abstract
6. 60260 DMID-LS-139; PUBMED-DMID-2/26/2007
Human Rhinovirus 3C Protease as a Potential Target for the Development of Antiviral Agents
Wanga, QM and Chen, SH
Curr Protein Pept Sci 20067. 8(1): 19-27
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17305557&dopt=abstract
7. 60261 DMID-LS-139; PUBMED-DMID-2/26/2007
Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo
Hayashi, K, Imanishi, N, Kashiwayama, Y, Kawano, A, Terasawa, K, Shimada, Y, and Ochiai, H
Antiviral Res 2007.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17303260&dopt=abstract
8. 60262 DMID-LS-139; WOS-DMID-2/26/2007
Efficient Synthesis of (S)-2-(Cyclopentyloxycarbonyl)-Amino-8-Nonenoic Acid: Key Building Block for Biln 2061, an Hcvns3 Protease Inhibitor
Wang, X. et al.
Organic Process Research & Development 2007. 11(1): 60-63
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243560000009
9. 60263 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Preparation of macrocyclic inhibitors of hepatitis C virus
Raboisson, Pierre Jean-Marie Bernard, De Kock, Herman Augustinus, Hu, Lili, Simmen, Kenneth Alan, Lindquist, Karin Charlotta, Lindstroem, Mats Stefan, Belfrage, Anna Karin Gertrud Linnea, Waehling, Horst Juergen, Nilsson, Karl Magnus, Samuelsson, Bengt Bertil, Rosenquist, Aasa Annica Kristina, Sahlberg, Sven Crister, Wallberg, Hans Kristian, Kahnberg, Pia Cecilia, and Classon, Bjoern Olof
PATENT: WO 2007014927 ISSUE DATE: 20070208
APPLICATION: 2006 PP: 158pp.
ASSIGNEE: (Tibotec Pharmaceuticals Ltd., Ire. and Medivir AB)
10. 60264 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Preparation of N-prolyl-1-aminocyclopropanecarboxylic acid peptides as antiviral agents
Casarez, Anthony, Chaudhary, Kleem, Kim, Choung U, McMurtrie, Darren, and Sheng, Xiaoning C
PATENT: WO 2007011658 ISSUE DATE: 20070125
APPLICATION: 2006 PP: 190pp.
ASSIGNEE: (Gilead Sciences, Inc. USA
11. 60265 DMID-LS-139; PUBMED-DMID-2/26/2007
Structure-activity relationship studies on anti-HCV activity of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system
Zhang, P, Zhang, N, Korba, BE, and Hosmane, RS
Bioorg Med Chem Lett 2007.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17300935&dopt=abstract
12. 60266 DMID-LS-139; WOS-DMID-2/26/2007
Valopicitabine Dihydrochloride: a Specific Polymerase Inhibitor of Hepatitis C Virus
Toniutto, P. et al.
Current Opinion in Investigational Drugs 2007. 8(2): 150-158
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243838800007
13. 60267 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Inhibitors of serine proteases
Lyons, Steve and Perni, Robert B
PATENT: WO 2007016589 ISSUE DATE: 20070208
APPLICATION: 2006 PP: 86pp.
ASSIGNEE: (Vertex Pharmaceuticals Incorporated, USA
14. 60268 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Antiviral deoxyribozymes targeting hepatitis C core antigen RNA
Alfieri, Carolina, Trepanier, Janie, Tanner, Jerome E, and Momparler, Richard
PATENT: WO 2007014469 ISSUE DATE: 20070208
APPLICATION: 2006 PP: 100pp.
ASSIGNEE: (Chu Sainte-Justine, Le Centre Hospitalier Universitaire Mere-Enfant Can.
15. 60269 DMID-LS-139; PUBMED-DMID-2/26/2007
Protocatechuic aldehyde inhibits hepatitis B virus replication both in vitro and in vivo
Zhou, Z, Zhang, Y, Ding, XR, Chen, SH, Yang, J, Wang, XJ, Jia, GL, Chen, HS, Bo, XC, and Wang, SQ
Antiviral Res 2007.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17298850&dopt=abstract
16. 60270 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Preparation of macrocyclic compounds as HCV NS3 protease inhibitors
Holloway, MKatharine, Liverton, Nigel J, Ludmerer, Steven W, Mccauley, John A, Olsen, David B, Rudd, Michael T, Vacca, Joseph P, and Mcintyre, Charles J
PATENT: US 2007027071 ISSUE DATE: 20070201
APPLICATION: 2006-26173 PP: 142pp.
ASSIGNEE: (USA)
17. 60271 DMID-LS-139; PUBMED-DMID-2/26/2007
Efficacy of oseltamivir therapy in ferrets inoculated with different clades of H5N1 influenza virus
Govorkova, EA, Ilyushina, NA, Boltz, DA, Douglas, A, Yilmaz, N, and Webster, RG
Antimicrob Agents Chemother 2007.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17296744&dopt=abstract
18. 60272 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Preparation of N-(piperazinylcarbonylazolyl)-N'-phenylureas as anti-cytomegalovirus agents
Zimmermann, Holger, Brueckner, David, Henninger, Kerstin, Hendrix, Martin, and Radtke, Martin
PATENT: DE 102005033103 ISSUE DATE: 20070125
APPLICATION: 2005 PP: 31pp.
ASSIGNEE: (Bayer Healthcare AG, Germany
19. 60273 DMID-LS-139; WOS-DMID-2/26/2007
Natural Products and Chronic Hepatitis C Virus
Azzam, H. et al.
Liver International 2007. 27(1): 17-25
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243534600004
20. 60274 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Preparation of L-nucleosides as antiviral agents
Yuan, Jiandong, Zhang, Kai, and Ye, Xinjian
PATENT: CN 1891710 ISSUE DATE: 20070110
APPLICATION: 1004 PP: 30pp.
ASSIGNEE: (Brightgene Bio-Medical (Suzhou) Co., Ltd. Peop. Rep. China
21. 60275 DMID-LS-139; SCIFINDER-DMID-2/26/2007
The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: Synthesis, cytostatic, and antiviral activity evaluations
Gazivoda, Tatjana, Raic-Malic, Silvana, Marjanovic, Marko, Kralj, Marijeta, Pavelic, Kresimir, Balzarini, Jan, De Clercq, Erik, and Mintas, Mladen
Bioorganic & Medicinal Chemistry 2007. 15(2): 749-758
22. 60276 DMID-LS-139; WOS-DMID-2/26/2007
The Kinetics of Hepatitis C Virus
Herrmann, E. and Zeuzem, S.
European Journal of Gastroenterology & Hepatology 2006 . 18(4): 339-342
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243484200006
23. 60277 DMID-LS-139; WOS-DMID-2/26/2007
Impact of Human Immune Deficiency Virus Infection on Hepatitis C Virus Infection and Replication
Parodi, C. et al.
Current Hiv Research 2007. 5(1): 55-67
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243501800005
24. 60278 DMID-LS-139; PUBMED-DMID-2/26/2007
A dengue Fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs
Schul, W, Liu, W, Xu, HY, Flamand, M, and Vasudevan, SG
J Infect Dis 2007. 195(5): 665-74
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17262707&dopt=abstract
25. 60279 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Recent patents on treatment of severe acute respiratory syndrome (SARS)
Zhai, Shumei, Liu, Wei, and Yan, Bing
Recent Patents on Anti-Infective Drug Discovery 2007. 2(1 ): 1-10
26. 60280 DMID-LS-139; SCIFINDER-DMID-2/26/2007
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice
Roberts, Anjeanette, Deming, Damon, Paddock, Christopher D, Cheng, Aaron, Yount, Boyd, Vogel, Leatrice, Herman, Brian D, Sheahan, Tim, Heise, Mark, Genrich, Gillian L, Zaki, Sherif R, Baric, Ralph, and Subbarao, Kanta
PLoS Pathogens 2007. 3(1): 23-37
27. 60281 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Preparation of prolyl tripeptides as hepatitis C virus inhibitors
Hewawasam, Piyasena, Ding, Min, Sun, Li-Qiang, and Scola, Paul Michael
PATENT: US 2007010455 ISSUE DATE: 20070111
APPLICATION: 2006-22784 PP: 86pp.
ASSIGNEE: (USA)
28. 60282 DMID-LS-139; WOS-DMID-2/26/2007
Antiviral Activity of Cyclopropavir and Ether Lipid Esters of Cidofovir Against Hhv6 and Other Human Herpesviruses
Prichard, M.
Journal of Clinical Virology 2006. 37: S112
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243845000077
29. 60283 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Antiviral phosphoramidates
Klumpp, Klaus, Martin, Joseph Armstrong, Mcguigan, Christopher, and Smith, David Bernard
PATENT: WO 2007020193 ISSUE DATE: 20070222
APPLICATION: 2006
ASSIGNEE: (F. Hoffmann-La Roche A.-G., Switz.
30. 60284 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Application of multi-substituted acyl thiouracil derivant in preparation of antiviral drug
Zhou, Pei, Feng, Meiqing, Sun, Chuanwen, Huang, Hai, and Zhou, Wei
PATENT: CN 1903203 ISSUE DATE: 20070131
APPLICATION: 1002-8153 PP: 11pp.
ASSIGNEE: (Fudan University, Peop. Rep. China
31. 60285 DMID-LS-139; SCIFINDER-DMID-2/26/2007
Pyrrolo[2,3-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases
Ibrahim, Prahbha N, Artis, Dean R, Bremer, Ryan, Mamo, Shumeye, Nespi, Marika, Zhang, Chao, Zhang, Jiazhong, Zhu, Yong-Liang, Tsai, James, Hirth, Klaus-Peter, Bollag, Gideon, Spevak, Wayne, Cho, Hanna, Gillette, Samuel J, Wu, Guoxiam, Zhu, Hongyao, and Shi, Shenghua
PATENT: WO 2007002325 ISSUE DATE: 20070104
APPLICATION: 2006 PP: 291 pp.
ASSIGNEE: (Plexxikon, Inc. USA
32. 60286 DMID-LS-139; WOS-DMID-2/26/2007
Preventing and Treating Influenza
Baum, S. and Carey, J.
Infections in Medicine 2007. 24(1): 13-+
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243830700006
33. 60287 DMID-LS-139; WOS-DMID-2/26/2007
Human Rhinovirus 3c Protease as a Potential Target for the Development of Antiviral Agents
Wang, Q. and Chen, S.
Current Protein & Peptide Science 2007. 8(1): 19-27
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243632700003
34. 60288 DMID-LS-139; WOS-DMID-2/26/2007
Anti-Enterovirus Activity and Structure-Activity Relationship of a Series of 2,6-Dihalophenyl-Substituted 1h,3h-Thiazolo[3,4-a]Benzimidazoles
De Palma, A. et al.
Biochemical and Biophysical Research Communications 2007. 353(3): 628-632
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243570000017
35. 60289 DMID-LS-139; WOS-DMID-2/26/2007
Human Influenza a (H5n1): a Brief Review and Recommendations for Travelers
Hurtado, T.
Wilderness & Environmental Medicine 2006. 17(4): 276-281
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243309400009
36. 60290 DMID-LS-139; WOS-DMID-2/26/2007
Long-Term Inhibition of Hepatitis B Virus in Transgenic Mice by Double-Stranded Adeno-Associated Virus 8-Delivered Short Hairpin Rna
Chen, C. et al.
Gene Therapy 2007. 14(1): 11-19
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243255300002