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1. 60255 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Pyrrolidine derivatives as immunomodulators and antiviral agents

Nash, Robert James, Carroll, Miles William, Watson, Alison Ann, Fleet, George William John, and Horne, Graeme

PATENT: WO 2007010266 ISSUE DATE: 20070125

APPLICATION: 2006 PP: 72pp.

ASSIGNEE: (MNL Pharma Limited, UK

2. 60256 DMID-LS-139; PUBMED-DMID-2/26/2007

Dysoxylins A-D, Tetranortriterpenoids with Potent Anti-RSV Activity from Dysoxylum gaudichaudianum

Chen, JL, Kernan, MR, Jolad, SD, Stoddart, CA, Bogan, M, and Cooper, R

J Nat Prod 2007. 70(2): 312-5


3. 60257 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Synthetic single strand deoxynucleosides for antiviral uses

Wang, Li-Ying, Bao, Mu-Sheng, and Yu, Yong-Li

PATENT: WO 2007012285 ISSUE DATE: 20070201

APPLICATION: 2006 PP: 62pp.

ASSIGNEE: (Changchun Huapu Biotechnology Co., Ltd. Peop. Rep. China

4. 60258 DMID-LS-139; PUBMED-DMID-2/26/2007

Molecular diagnostics of hepatitis C virus infection: a systematic review

Scott, JD and Gretch, DR

JAMA 2007. 297(7): 724-32


5. 60259 DMID-LS-139; PUBMED-DMID-2/26/2007

Proteases essential for human influenza virus entry into cells and their inhibitors as potential therapeutic agents

Kido, H, Okumura, Y, Yamada, H, Le, TQ, and Yano, M

Curr Pharm Des 2007. 13(3): 403-12


6. 60260 DMID-LS-139; PUBMED-DMID-2/26/2007

Human Rhinovirus 3C Protease as a Potential Target for the Development of Antiviral Agents

Wanga, QM and Chen, SH

Curr Protein Pept Sci 20067. 8(1): 19-27


7. 60261 DMID-LS-139; PUBMED-DMID-2/26/2007

Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo

Hayashi, K, Imanishi, N, Kashiwayama, Y, Kawano, A, Terasawa, K, Shimada, Y, and Ochiai, H

Antiviral Res 2007.


8. 60262 DMID-LS-139; WOS-DMID-2/26/2007

Efficient Synthesis of (S)-2-(Cyclopentyloxycarbonyl)-Amino-8-Nonenoic Acid: Key Building Block for Biln 2061, an Hcvns3 Protease Inhibitor

Wang, X. et al.

Organic Process Research & Development 2007. 11(1): 60-63


9. 60263 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Preparation of macrocyclic inhibitors of hepatitis C virus

Raboisson, Pierre Jean-Marie Bernard, De Kock, Herman Augustinus, Hu, Lili, Simmen, Kenneth Alan, Lindquist, Karin Charlotta, Lindstroem, Mats Stefan, Belfrage, Anna Karin Gertrud Linnea, Waehling, Horst Juergen, Nilsson, Karl Magnus, Samuelsson, Bengt Bertil, Rosenquist, Aasa Annica Kristina, Sahlberg, Sven Crister, Wallberg, Hans Kristian, Kahnberg, Pia Cecilia, and Classon, Bjoern Olof

PATENT: WO 2007014927 ISSUE DATE: 20070208

APPLICATION: 2006 PP: 158pp.

ASSIGNEE: (Tibotec Pharmaceuticals Ltd., Ire. and Medivir AB)

10. 60264 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Preparation of N-prolyl-1-aminocyclopropanecarboxylic acid peptides as antiviral agents

Casarez, Anthony, Chaudhary, Kleem, Kim, Choung U, McMurtrie, Darren, and Sheng, Xiaoning C

PATENT: WO 2007011658 ISSUE DATE: 20070125

APPLICATION: 2006 PP: 190pp.

ASSIGNEE: (Gilead Sciences, Inc. USA

11. 60265 DMID-LS-139; PUBMED-DMID-2/26/2007

Structure-activity relationship studies on anti-HCV activity of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system

Zhang, P, Zhang, N, Korba, BE, and Hosmane, RS

Bioorg Med Chem Lett 2007.


12. 60266 DMID-LS-139; WOS-DMID-2/26/2007

Valopicitabine Dihydrochloride: a Specific Polymerase Inhibitor of Hepatitis C Virus

Toniutto, P. et al.

Current Opinion in Investigational Drugs 2007. 8(2): 150-158


13. 60267 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Inhibitors of serine proteases

Lyons, Steve and Perni, Robert B

PATENT: WO 2007016589 ISSUE DATE: 20070208

APPLICATION: 2006 PP: 86pp.

ASSIGNEE: (Vertex Pharmaceuticals Incorporated, USA

14. 60268 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Antiviral deoxyribozymes targeting hepatitis C core antigen RNA

Alfieri, Carolina, Trepanier, Janie, Tanner, Jerome E, and Momparler, Richard

PATENT: WO 2007014469 ISSUE DATE: 20070208

APPLICATION: 2006 PP: 100pp.

ASSIGNEE: (Chu Sainte-Justine, Le Centre Hospitalier Universitaire Mere-Enfant Can.

15. 60269 DMID-LS-139; PUBMED-DMID-2/26/2007

Protocatechuic aldehyde inhibits hepatitis B virus replication both in vitro and in vivo

Zhou, Z, Zhang, Y, Ding, XR, Chen, SH, Yang, J, Wang, XJ, Jia, GL, Chen, HS, Bo, XC, and Wang, SQ

Antiviral Res 2007.


16. 60270 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Preparation of macrocyclic compounds as HCV NS3 protease inhibitors

Holloway, MKatharine, Liverton, Nigel J, Ludmerer, Steven W, Mccauley, John A, Olsen, David B, Rudd, Michael T, Vacca, Joseph P, and Mcintyre, Charles J

PATENT: US 2007027071 ISSUE DATE: 20070201

APPLICATION: 2006-26173 PP: 142pp.


17. 60271 DMID-LS-139; PUBMED-DMID-2/26/2007

Efficacy of oseltamivir therapy in ferrets inoculated with different clades of H5N1 influenza virus

Govorkova, EA, Ilyushina, NA, Boltz, DA, Douglas, A, Yilmaz, N, and Webster, RG

Antimicrob Agents Chemother 2007.


18. 60272 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Preparation of N-(piperazinylcarbonylazolyl)-N'-phenylureas as anti-cytomegalovirus agents

Zimmermann, Holger, Brueckner, David, Henninger, Kerstin, Hendrix, Martin, and Radtke, Martin

PATENT: DE 102005033103 ISSUE DATE: 20070125

APPLICATION: 2005 PP: 31pp.

ASSIGNEE: (Bayer Healthcare AG, Germany

19. 60273 DMID-LS-139; WOS-DMID-2/26/2007

Natural Products and Chronic Hepatitis C Virus

Azzam, H. et al.

Liver International 2007. 27(1): 17-25


20. 60274 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Preparation of L-nucleosides as antiviral agents

Yuan, Jiandong, Zhang, Kai, and Ye, Xinjian

PATENT: CN 1891710 ISSUE DATE: 20070110

APPLICATION: 1004 PP: 30pp.

ASSIGNEE: (Brightgene Bio-Medical (Suzhou) Co., Ltd. Peop. Rep. China

21. 60275 DMID-LS-139; SCIFINDER-DMID-2/26/2007

The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: Synthesis, cytostatic, and antiviral activity evaluations

Gazivoda, Tatjana, Raic-Malic, Silvana, Marjanovic, Marko, Kralj, Marijeta, Pavelic, Kresimir, Balzarini, Jan, De Clercq, Erik, and Mintas, Mladen

Bioorganic & Medicinal Chemistry 2007. 15(2): 749-758

22. 60276 DMID-LS-139; WOS-DMID-2/26/2007

The Kinetics of Hepatitis C Virus

Herrmann, E. and Zeuzem, S.

European Journal of Gastroenterology & Hepatology 2006 . 18(4): 339-342


23. 60277 DMID-LS-139; WOS-DMID-2/26/2007

Impact of Human Immune Deficiency Virus Infection on Hepatitis C Virus Infection and Replication

Parodi, C. et al.

Current Hiv Research 2007. 5(1): 55-67


24. 60278 DMID-LS-139; PUBMED-DMID-2/26/2007

A dengue Fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs

Schul, W, Liu, W, Xu, HY, Flamand, M, and Vasudevan, SG

J Infect Dis 2007. 195(5): 665-74


25. 60279 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Recent patents on treatment of severe acute respiratory syndrome (SARS)

Zhai, Shumei, Liu, Wei, and Yan, Bing

Recent Patents on Anti-Infective Drug Discovery 2007. 2(1 ): 1-10

26. 60280 DMID-LS-139; SCIFINDER-DMID-2/26/2007

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

Roberts, Anjeanette, Deming, Damon, Paddock, Christopher D, Cheng, Aaron, Yount, Boyd, Vogel, Leatrice, Herman, Brian D, Sheahan, Tim, Heise, Mark, Genrich, Gillian L, Zaki, Sherif R, Baric, Ralph, and Subbarao, Kanta

PLoS Pathogens 2007. 3(1): 23-37

27. 60281 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Preparation of prolyl tripeptides as hepatitis C virus inhibitors

Hewawasam, Piyasena, Ding, Min, Sun, Li-Qiang, and Scola, Paul Michael

PATENT: US 2007010455 ISSUE DATE: 20070111

APPLICATION: 2006-22784 PP: 86pp.


28. 60282 DMID-LS-139; WOS-DMID-2/26/2007

Antiviral Activity of Cyclopropavir and Ether Lipid Esters of Cidofovir Against Hhv6 and Other Human Herpesviruses

Prichard, M.

Journal of Clinical Virology 2006. 37: S112


29. 60283 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Antiviral phosphoramidates

Klumpp, Klaus, Martin, Joseph Armstrong, Mcguigan, Christopher, and Smith, David Bernard

PATENT: WO 2007020193 ISSUE DATE: 20070222


ASSIGNEE: (F. Hoffmann-La Roche A.-G., Switz.

30. 60284 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Application of multi-substituted acyl thiouracil derivant in preparation of antiviral drug

Zhou, Pei, Feng, Meiqing, Sun, Chuanwen, Huang, Hai, and Zhou, Wei

PATENT: CN 1903203 ISSUE DATE: 20070131

APPLICATION: 1002-8153 PP: 11pp.

ASSIGNEE: (Fudan University, Peop. Rep. China

31. 60285 DMID-LS-139; SCIFINDER-DMID-2/26/2007

Pyrrolo[2,3-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases

Ibrahim, Prahbha N, Artis, Dean R, Bremer, Ryan, Mamo, Shumeye, Nespi, Marika, Zhang, Chao, Zhang, Jiazhong, Zhu, Yong-Liang, Tsai, James, Hirth, Klaus-Peter, Bollag, Gideon, Spevak, Wayne, Cho, Hanna, Gillette, Samuel J, Wu, Guoxiam, Zhu, Hongyao, and Shi, Shenghua

PATENT: WO 2007002325 ISSUE DATE: 20070104

APPLICATION: 2006 PP: 291 pp.

ASSIGNEE: (Plexxikon, Inc. USA

32. 60286 DMID-LS-139; WOS-DMID-2/26/2007

Preventing and Treating Influenza

Baum, S. and Carey, J.

Infections in Medicine 2007. 24(1): 13-+


33. 60287 DMID-LS-139; WOS-DMID-2/26/2007

Human Rhinovirus 3c Protease as a Potential Target for the Development of Antiviral Agents

Wang, Q. and Chen, S.

Current Protein & Peptide Science 2007. 8(1): 19-27


34. 60288 DMID-LS-139; WOS-DMID-2/26/2007

Anti-Enterovirus Activity and Structure-Activity Relationship of a Series of 2,6-Dihalophenyl-Substituted 1h,3h-Thiazolo[3,4-a]Benzimidazoles

De Palma, A. et al.

Biochemical and Biophysical Research Communications 2007. 353(3): 628-632


35. 60289 DMID-LS-139; WOS-DMID-2/26/2007

Human Influenza a (H5n1): a Brief Review and Recommendations for Travelers

Hurtado, T.

Wilderness & Environmental Medicine 2006. 17(4): 276-281


36. 60290 DMID-LS-139; WOS-DMID-2/26/2007

Long-Term Inhibition of Hepatitis B Virus in Transgenic Mice by Double-Stranded Adeno-Associated Virus 8-Delivered Short Hairpin Rna

Chen, C. et al.

Gene Therapy 2007. 14(1): 11-19



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