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1. 60358 DMID-LS-140; PUBMED-DMID-3/12/2007

Antiviral strategies against human coronaviruses

Pyrc, K, Berkhout, B, and van der Hoek, L

Infect Disord Drug Targets 2007. 7(1): 59-66


2. 60359 DMID-LS-140; PUBMED-DMID-3/12/2007

Novel targets for the development of anti-herpes compounds

Greco, A, Diaz, JJ, Thouvenot, D, and Morfin, F

Infect Disord Drug Targets 2007. 7(1): 11-8


3. 60360 DMID-LS-140; WOS-DMID-3/12/2007

Specific Inhibition of Hbv Replication in Vitro and in Vivo With Expressed Long Hairpin Rna

Weinberg, M. et al.

Molecular Therapy 2007. 15(3): 534-541


4. 60361 DMID-LS-140; WOS-DMID-3/12/2007

Antivirals of Ethnomedicinal Origin: Structure-Activity Relationship and Scope

Chattopadhyay, D. and Naik, T.

Mini-Reviews in Medicinal Chemistry 2007. 7(3): 275-301


5. 60362 DMID-LS-140; PUBMED-DMID-3/12/2007

1,4-Benzodiazepines as Inhibitors of Respiratory Syncytial Virus. The Identification of a Clinical Candidate

Henderson, EA, Alber, DG, Baxter, RC, Bithell, SK, Budworth, J, Carter, MC, Chubb, A, Cockerill, GS, Dowdell, VC, Fraser, IJ, Harris, RA, Keegan, SJ, Kelsey, RD, Lumley, JA, Stables, JN, Weerasekera, N, Wilson, LJ, and Powell, KL

J Med Chem 2007.


6. 60363 DMID-LS-140; PUBMED-DMID-3/12/2007

Functional characterization of cis and trans protease activity of the flavivirus NS2B-NS3 protease

Bera, AK, Kuhn, RJ, and Smith, JL

J Biol Chem 2007.


7. 60364 DMID-LS-140; WOS-DMID-3/12/2007

Anti-Viral Effects, Pharmacokinetics and Safety of Two Human Monoclonal Anti-Hbs (Libivirumab/Exbivirumab) Versus Hepatitis B Immune Globulin (Hbig) in Hepatits B Virus (Hbv) in Liver Transplant (Lt) Recipients

Shouval, D. et al.

Hepatology 2006. 44(4): 196A


8. 60365 DMID-LS-140; PUBMED-DMID-3/12/2007

An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents

Tsoukala, E, Agelis, G, Dolinsek, J, Botic, T, Cencic, A, and Komiotis, D

Bioorg Med Chem 2007.


9. 60366 DMID-LS-140; EMBASE-DMID-3/12/2007

Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region

Shiryaev, Sergey A, Aleshin, Alexander E, Ratnikov, Boris I, Smith, Jeffrey W, Liddington, Robert C, and Strongin, Alex Y

Protein Expression and Purification 2007. 52(2): 334-339


10. 60367 DMID-LS-140; PUBMED-DMID-3/12/2007

Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents

Ikejiri, M, Saijo, M, Morikawa, S, Fukushi, S, Mizutani, T, Kurane, I, and Maruyama, T

Bioorg Med Chem Lett 2007.


11. 60368 DMID-LS-140; WOS-DMID-3/12/2007

Inhibitory Activity of the 2,4-Diamino-6-[2-(Phosphonomethoxy)Ethoxy]-Pyrimidine (Pmeo) Against Wild Type and Drug Resistant Mutants of Hbv

Brunelle, M. et al.

Hepatology 2006. 44(4): 223A-224A


12. 60369 DMID-LS-140; PUBMED-DMID-3/12/2007

Antiviral effect of octyl gallate against influenza and other RNA viruses

Yamasaki, H, Uozaki, M, Katsuyama, Y, Utsunomiya, H, Arakawa, T, Higuchi, M, Higuti, T, and Koyama, AH

Int J Mol Med 2007. 19(4): 685-8


13. 60370 DMID-LS-140; WOS-DMID-3/12/2007

Discovery, Characterization and Anti-Hcv Activity of a Novel Ns5b Inhibitor

Wagner, R. et al.

Hepatology 2006. 44(4): 236A-237A


14. 60371 DMID-LS-140; EMBASE-DMID-3/12/2007

Characterization of the Intracellular Metabolism of [beta]-d-2'-Deoxy-2'-Fluoro-2'-C-Methyl-Cytidine and the Inhibition of HCV Polymerase NS5B by its 5'-Triphosphate Species

Ma, Han, Jiang, Wen-Rong, Robledo, Nicole, Leveque, Vincent, Ali, Samir, Smith, David, Masjedizadeh, Mohammad, Lara-Jaime, Teresa, Cammack, Nick, Klumpp, Klaus, and Symons, Julian

Antiviral Research 2007. In Press, Uncorrected Proof: 2874


15. 60372 DMID-LS-140; PUBMED-DMID-3/12/2007

Hepatitis C Virus Infection-Pathobiology and Implications for New Therapeutic Options

Davis, GL, Krawczynski, K, and Szabo, G

Dig Dis Sci 2007.


16. 60373 DMID-LS-140; EMBASE-DMID-3/12/2007

Sub Micromolar Inhibitors of HCV Generated from Inactive Nucleosides by Application of ProTide Technology

McGuigan, Christopher, Perrone, Plinio, Luoni, Giovanna, Kelleher, Mary Rose, Daverio, Felice, Angell, Annette, Mulready, Sinead, Congiatu, Costantino, Rajyaguru, Sonal, Martin, Joseph, Leveque, Vincent, Le Pogam, Sophie, Najera, Isabel, Klumpp, Klaus, and Smith, David

Antiviral Research 2007. In Press, Uncorrected Proof: 2874


17. 60374 DMID-LS-140; EMBASE-DMID-3/12/2007

Substituted Imidazopyridines as Potent Inhibitors of Hepatitis C Virus Replication that Target the Viral Polymerase

Vliegen, Inge, Paeshuyse, Jan, Lehman, Laura S, Zhong, Weidong, Roofthooft, Sofie, Dutartre, Helene, Selisko, Barbara, Canard, Bruno, Boddeker, Nina, Bondy, Steven, Oare, David, De Clercq, Erik, Lee, William A, Purstinger, Gerhard, and Neyts, Johan

Antiviral Research 2007. In Press, Uncorrected Proof: 2874


18. 60375 DMID-LS-140; PUBMED-DMID-3/12/2007

6-Hydrazinopurine 2'-methyl ribonucleosides and their 5'-monophosphate prodrugs as potent hepatitis C virus inhibitors

Gunic, E, Chow, S, Rong, F, Ramasamy, K, Raney, A, Yunzhi, Li D, Huang, J, Hamatake, RK, Hong, Z, and Girardet, JL

Bioorg Med Chem Lett 2007.


19. 60376 DMID-LS-140; PUBMED-DMID-3/12/2007

Cowaniin, a C-glucosidic ellagitannin dimer linked through catechin from Cowania mexicana

Ito, H, Miyake, M, Nishitani, E, Miyashita, K, Yoshimura, M, Yoshida, T, Takasaki, M, Konoshima, T, Kozuka, M, and Hatano, T

Chem Pharm Bull (Tokyo) 2007. 55(3): 492-4


20. 60377 DMID-LS-140; EMBASE-DMID-3/12/2007

7-Deaza Neplanocin Analogs Inhibit Hepatitis C Virus (HCV) in Vitro

Kim, HJ, Wang, JN, Huang, ZH, Murray, MG, Schinazi, RF, and Chu, CK

Antiviral Research 2007. In Press, Uncorrected Proof: 2874


21. 60378 DMID-LS-140; EMBASE-DMID-3/12/2007

Potent HCV NS5B Polymerase Inhibitors Derived From 5-Hydroxy-3(2H)-Pyridazinones: Part 2: Variation of the 2- and 6- Pyridazinone Substituents

Zhou, Y, Li, L-S, Webber, S, Ayida, B, Bertolini, T, Sun, Z, Zhao, J, Stankovic, N, Patel, R, Li, B, LeBrun, L, Kamran, R, Sergeeva, M, Bartkowski, D, and Khandurina, J

Antiviral Research 2007. In Press, Uncorrected Proof: 2874


22. 60379 DMID-LS-140; EMBASE-DMID-3/12/2007

Discovery of Two Novel Classes of Inhibitors of Hepatitis C Virus (HCV) Replication utilizing a Dicistronic Reporter HCV Replicon High Throughput Assay

Hao, Weidong, Weady, Peter, Maldonado, Fausto, Patick, Amy, and Duggal, Rohit

Antiviral Research 2007. In Press, Uncorrected Proof: 2874


23. 60380 DMID-LS-140; WOS-DMID-3/12/2007

The Antiviral Efficacy of an Hcv Polymerase Inhibitor in the Chimpanzee Model: Genotypic and Phenotypic Analyses

Chen, C. et al.

Hepatology 2006. 44(4): 342A-343A


24. 60381 DMID-LS-140; WOS-DMID-3/12/2007

The Cyclophilin Inhibitor Debio-025 Is a Potent Inhibitor of Hepatitis C Virus Replication in Vitro

Paeshuyse, J. et al.

Hepatology 2006. 44(4): 346A


25. 60382 DMID-LS-140; WOS-DMID-3/12/2007

In Vitro Antiviral Effects of Combinations of Abbott Hcv Polymerase Inhibitors With Ifn or Ns3/4a Protease Inhibitors

Koev, G. et al.

Hepatology 2006. 44(4): 346A


26. 60383 DMID-LS-140; PUBMED-DMID-3/12/2007

Finding new medicines for flaviviral targets

Keller, TH, Chen, YL, Knox, JE, Lim, SP, Ma, NL, Patel, SJ, Sampath, A, Wang, QY, Yin, Z, and Vasudevan, SG

Novartis Found Symp 2006. 277: 102-14; discussion 114-9, 251-3


27. 60384 DMID-LS-140; PUBMED-DMID-3/12/2007

Towards the design of flavivirus helicase/NTPase inhibitors: crystallographic and mutagenesis studies of the dengue virus NS3 helicase catalytic domain

Xu, T, Sampath, A, Chao, A, Wen, D, Nanao, M, Luo, D, Chene, P, Vasudevan, SG, and Lescar, J

Novartis Found Symp 2006. 277: 87-97; discussion 97-101, 251-3


28. 60385 DMID-LS-140; EMBASE-DMID-3/12/2007

Enhanced Antiviral Activity of Hexadecyloxypropyl-PME-N6-Cyclopropyl-diaminopurine Against Herpesviruses, Hepatitis B Virus and Vaccinia Virus, In Vitro

Andrei, Graciela, Snoeck, Robert, Neyts, Johan, De Clercq, Erik, Valiaeva, Nadejda, Beadle, James, and Hostetler, Karl

Antiviral Research 2007. In Press, Uncorrected Proof


29. 60386 DMID-LS-140; PUBMED-DMID-3/12/2007

Development of novel antivirals against flaviviruses

Patkar, CG and Kuhn, RJ

Novartis Found Symp 2006. 277: 41-52; discussion 52-6, 71-3, 251-3


30. 60387 DMID-LS-140; WOS-DMID-3/12/2007

In Vitro Antiviral Interactions of a Novel Hcv Inhibitor R1479 With Interferon Alpha-2a, Ribavirin and Other Hcv Inhibitors

Jiang, W. et al.

Hepatology 2006. 44(4): 533A


31. 60388 DMID-LS-140; PUBMED-DMID-3/12/2007

Hepatitis C virus infection, cryoglobulinaemia, and beyond

Sansonno, D, Carbone, A, De, Re V, and Dammacco, F

Rheumatology (Oxford) 2007.


32. 60389 DMID-LS-140; WOS-DMID-3/12/2007

In Vitro Synergistic Antiviral Activity of Itmn-191, an Orally Active Inhibitor of the Hepatitis C Virus (Hcv) Ns3/4a Protease, in Combination With Peg-Interferon Alfa-2a

Tan, H., Seiwert, S., and Blatt, L.

Hepatology 2006. 44(4): 534A


33. 60390 DMID-LS-140; WOS-DMID-3/12/2007

Preclinical Evaluation of Scy-635, a Cyclophilin Inhibitor With Potent Anti-Hcv Activity

Houck, D. and Hopkins, S.

Hepatology 2006. 44(4): 534A-535A


34. 60391 DMID-LS-140; WOS-DMID-3/12/2007

Induction of Resistance by a Novel Class of Compounds Active Against Hepatitis C Virus With No Cross-Resistance to Ns3 Protease and Ns5b Polymerase Inhibitors

Yang, W. et al.

Hepatology 2006. 44(4): 536A


35. 60392 DMID-LS-140; WOS-DMID-3/12/2007

A Common Molecular Pathway Leads to Inhibition of Interferon-Alpha Signaling in Both Hepatitis B and Hepatitis C Virus Infection

Christen, V. and Heim, M.

Hepatology 2006. 44(4): 546A-547A


36. 60393 DMID-LS-140; PUBMED-DMID-3/12/2007

Synergistic copathogens--HIV-1 and HSV-2

Corey, L

N Engl J Med 2007. 356(8): 854-6


37. 60394 DMID-LS-140; WOS-DMID-3/12/2007

The Cyclophilin Inhibitor Debio-025 Has a Potent Dual Anti-Hiv and Anti-Hcv Activity in Treatment-Naive Hiv/Hcv Co-Infected Subjects

Flisiak, R. et al.

Hepatology 2006. 44(4): 609A


38. 60395 DMID-LS-140; WOS-DMID-3/12/2007

Interim Antiviral and Safety Data With Albumin Interferon Alfa-2b Combined With Ribavirin in a Phase 2b Study Conducted in a Genotype 1, Ifn-Naive, Chronic Hepatitis C Population

Mchutchison, J. et al.

Hepatology 2006. 44(4): 614A


39. 60396 DMID-LS-140; WOS-DMID-3/12/2007

Current Status of Subjects Receiving Peg-Interferon-Alfa-2a (Peg-Ifn) and Ribavirin (Rbv) After a 14-Day Study of the Hepatitis C Protease Inhibitor Telaprevir (Vx-950), With Peg-Ifn

Forestier, N. et al.

Hepatology 2006. 44(4): 614A-615A


40. 60397 DMID-LS-140; EMBASE-DMID-3/12/2007

Combined Anti-Influenza Virus Effect of a Plant Polyphenol-Rich Extract and Ribavirin

Serkedjieva, Julia and Teodosieva, Ani

Antiviral Research 2007. In Press, Uncorrected Proof: 200


41. 60398 DMID-LS-140; WOS-DMID-3/12/2007

Chloroquine Possesses a Potent Inhibitory Effect of Replication of Hcv Replicon

Mizui, T. et al.

Hepatology 2006. 44(4): 620A-621A


42. 60399 DMID-LS-140; EMBASE-DMID-3/12/2007

Anti-Influenza A Synergistic Combination Effect of Rimantadine and Oseltamivir in Mice

Simeonova, Lora, Galabov, Angel S, and Gegova, Galina

Antiviral Research 2007. In Press, Uncorrected Proof: 200


43. 60400 DMID-LS-140; WOS-DMID-3/12/2007

A Novel Class of Amphipathic Dna Polymers Inhibits Hepatitis C Virus Infection by Blocking Viral Entry

Matsumura, T. et al.

Hepatology 2006. 44(4): 693A


44. 60401 DMID-LS-140; EMBASE-DMID-3/12/2007

Susceptibility of German Porcine H3N2 Influenza A viruses Against Existing Antiviral Drugs

Bauer, Katja, Schrader, Christina, Suess, Jochen, Wutzler, Peter, and Schmidtke, Michaela

Antiviral Research 2007. In Press, Uncorrected Proof: 200


45. 60402 DMID-LS-140; WOS-DMID-3/12/2007

Synthesis of Three Novel Nucleoside Analogs as Hepatitis B Virus Specific Antiviral Reagents

Niu, J. et al.

Hepatology 2006. 44(4): 699A-700A


46. 60403 DMID-LS-140; EMBASE-DMID-3/12/2007

Pharmacodynamics of NPI-5291, an Adamantane Class Compound, for Influenza A Viruses

McSharry, James, Zager, Kris, Weng, Qingmei, Chernoff, David, and Drusano, George

Antiviral Research 2007. In Press, Uncorrected Proof: 200


47. 60404 DMID-LS-140; EMBASE-DMID-3/12/2007

Design, Synthesis, and Biological Evaluation of Novel Anti-VZV Agents

Derudas, Marco, McGuigan, Christopher, Snoeck, Robert, Andrei, Graciella, De Clercq, Erik, and Balzarini, Jan

Antiviral Research 2007. In Press, Uncorrected Proof: 200


48. 60405 DMID-LS-140; PUBMED-DMID-3/12/2007

In vivo and in vitro antiviral activity of hyperoside extracted from Abelmoschus manihot (L) medik

Wu, LL, Yang, XB, Huang, ZM, Liu, HZ, and Wu, GX

Acta Pharmacol Sin 2007. 28(3): 404-9


49. 60406 DMID-LS-140; EMBASE-DMID-3/12/2007

The Ugi reaction in the generation of new nucleosides as potential antiviral and antileishmanial agents

Fan, Xuesen, Zhang, Xinying, Bories, Christian, Loiseau, Philippe M, and Torrence, Paul F

Bioorganic Chemistry 2007. 35(2): 121-136


50. 60407 DMID-LS-140; EMBASE-DMID-3/12/2007

Practical Synthesis of (-)-Carbocyclic Cytosine (Carbodine) and its In Vitro Antiviral Activity against Venezuelan Equine Encephalitis (VEE) Virus and Yellow Fever Virus

Rao, JR, Julander, JG, Sidwell, RW, and Chu, CK

Antiviral Research 2007. In Press, Uncorrected Proof: 136


51. 60408 DMID-LS-140; EMBASE-DMID-3/12/2007

Antiviral Activities of New Cidofovir Analogs Against Camelpox Virus, Used as a Model of Variola Virus, in Human Skin Equivalent Cultures

Duraffour, Sophie, Snoeck, Robert, Van Den Oord, Joost, Krecmerova, Marcela, Holy, Antonin, Crance, Jean-Marc, Garin, Daniel, De Clercq, Erik, and Andrei, Graciela

Antiviral Research 2007. In Press, Uncorrected Proof: 136


52. 60409 DMID-LS-140; EMBASE-DMID-3/12/2007

Development of a Cell-Based Assay for Identification of Viral Entry Inhibitors Against SARS-CoV by High Throughput Screening (HTS)

Zhang, Chengsheng, Feng, Yan, Wong, Gillian, Wang, Liping, Cechetto, Jonathan, Blanchard, Jan, Brown, Eric, and Mahony, James

Antiviral Research 2007. In Press, Uncorrected Proof: 136


53. 60410 DMID-LS-140; EMBASE-DMID-3/12/2007

The Combination of Anti-poxvirus Compounds ST-246 and TTP-018 are Synergistic In Vitro

Chen, Yali, Harver, Chris, Yang, Guang, Hruby, Dennis, Andrews, Robert, and Jordan, Robert

Antiviral Research 2007. In Press, Uncorrected Proof: 136


54. 60411 DMID-LS-140; WOS-DMID-3/12/2007

Bicyclol for Chronic Hepatitis C

Yang, X. et al.

Cochrane Database of Systematic Reviews 2007.(1)


55. 60412 DMID-LS-140; EMBASE-DMID-3/12/2007

Efficacy of 5-Halogenated 2'-Deoxyuridines on Vaccinia Virus Thymidine Kinase Positive and Negative Strains, and Influence of Cell Type on Antiviral Potency

Smee, Donald, Humphreys, Daniel, Hurst, Brett, and Sidwell, Robert

Antiviral Research 2007. In Press, Uncorrected Proof: 136


56. 60413 DMID-LS-140; WOS-DMID-3/12/2007

Neuraminidase Inhibitors Reduce Nitric Oxide Production in Influenza Virus-Infected and Gamma Interferon-Activated Raw 264.7 Macrophages

Kacergius, T. et al.

Pharmacological Reports 2006. 58(6): 924-930


57. 60414 DMID-LS-140; WOS-DMID-3/12/2007

A Line Probe Assay (Lipa) for Detecting Novel Hepatitis B Drug Resistance Mutations Associated With Entecavir, Tenofovir and Adefovir Dipivoxil Therapy

Doutreloigne, J. et al.

Hepatology 2006. 44(4): 552A-553A


58. 60415 DMID-LS-140; WOS-DMID-3/12/2007

Synthesis and Biological Activation of an Ethylene Glycol-Linked Amino Acid Conjugate of Cyclic Cidofovir

Eriksson, U. et al.

Bioorganic & Medicinal Chemistry Letters 2007. 17(3): 583-586


59. 60416 DMID-LS-140; WOS-DMID-3/12/2007

Ifn-Stimulated Gene 15 Functions as a Critical Antiviral Molecule Against Influenza, Herpes, and Sindbis Viruses

Lenschow, D. et al.

Proceedings of the National Academy of Sciences of the United States of America 2007. 104(4): 1371-1376


60. 60417 DMID-LS-140; WOS-DMID-3/12/2007

Antiviral Activity of Diverse Classes of Broad-Acting Agents and Natural Compounds in Hhv-6-Infected Lymphoblasts

Naesens, L. and De Clercq, E.

Journal of Clinical Virology 2006. 37: S112


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