ONLINE DATABASE SEARCH - DMID-LS-61-MEMO
1. 5674 DMID-LS-61; PUBMED-DMID-3/2/2004
Antiviral action of ribavirin in chronic hepatitis C
Pawlotsky, JM, Dahari, H, Neumann, AU, HezoDe C, Germanidis, G, Lonjon, I, Castera, L, and Dhumeaux, D
Gastroenterology 2004. 126(3): 703-14
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14988824&dopt=abstract
2. 5675 DMID-LS-61; PUBMED-DMID-3/2/2004
A new modified DNA enzyme that targets influenza virus A mRNA inhibits viral infection in cultured cells
Takahashi, H, Hamazaki, H, Habu, Y, Hayashi, M, Abe, T, Miyano-Kurosaki, N, and Takaku, H
FEBS Lett 2004. 560(1-3): 69-74
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14988000&dopt=abstract
3. 5676 DMID-LS-61; PUBMED-DMID-3/2/2004
Antiviral activity of caspase inhibitors: effect on picornaviral 2A proteinase
Deszcz, L, Seipelt, J, Vassilieva, E, Roetzer, A, and Kuechler, E
FEBS Lett 2004. 560(1-3): 51-5
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14987997&dopt=abstract
4. 5677 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Antiviral pyrazines and pharmaceutical compositions containing them((Toyama Chemical Co., Ltd. Japan)
Egawa, Hiroyuki, Sugita, Atsushi, and Furuta, Yosuke
PATENT: JP 2004043371 A2; ISSUE DATE: 20040212
APPLICATION: 2002-7517; PP: 41 pp.
5. 5678 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Methods for identification of inhibitors of Ebola virus nucleocapsid assembly for use in vaccines ((The Government of the United States of America, as Represented by the Secretary Department of Health and Human Services USA)
Nabel, Gary and Huang, Yue
PATENT: WO 2004007747 A2; ISSUE DATE: 20040122
APPLICATION: 2003; PP: 97 pp.
6. 5679 DMID-LS-61; PUBMED-DMID-3/2/2004
Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings
Chu, CM, Cheng, VC, Hung, IF, Wong, MM, Chan, KH, Chan, KS, Kao, RY, Poon, LL, Wong, CL, Guan, Y, Peiris, JS, and Yuen, KY
Thorax 2004. 59(3): 252-6
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14985565&dopt=abstract
7. 5680 DMID-LS-61; PUBMED-DMID-3/2/2004
Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase
Sienaert, R, Andrei, G, Snoeck, R, De Clercq, E, McGuigan, C, and Balzarini, J
Biochem Biophys Res Commun 2004. 315(4): 877-83
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14985094&dopt=abstract
8. 5681 DMID-LS-61; PUBMED-DMID-3/2/2004
Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure
Liu, Y, Stoll, VS, Richardson, PL, Saldivar, A, Klaus, JL, MolLa A, Kohlbrenner, W, and Kati, WM
Arch Biochem Biophys 2004. 421(2): 207-16
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14984200&dopt=abstract
9. 5682 DMID-LS-61; PUBMED-DMID-3/2/2004
Geldanamycin, a Ligand of Heat Shock Protein 90, Inhibits the Replication of Herpes Simplex Virus Type 1 In Vitro
Li, YH, Tao, PZ, Liu, YZ, and Jiang, JD
Antimicrob Agents Chemother 2004. 48(3): 867-872
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14982777&dopt=abstract
10. 5683 DMID-LS-61; PUBMED-DMID-3/2/2004
Effect of zinc salts on respiratory syncytial virus replication
Suara, RO and Crowe, JE Jr
Antimicrob Agents Chemother 2004. 48(3): 783-90
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14982765&dopt=abstract
11. 5684 DMID-LS-61; PUBMED-DMID-3/2/2004
Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques
Haagmans, BL, Kuiken, T, Martina, BE, Fouchier, RA, Rimmelzwaan, GF, Van Amerongen, G, Van Riel, D, De Jong, T, Itamura, S, Chan, KH, Tashiro, M, and Osterhaus, AD
Nat Med 2004. 10(3): 290-3
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14981511&dopt=abstract
12. 5685 DMID-LS-61; PUBMED-DMID-3/2/2004
Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives
Yu, KL, Zhang, Y, Civiello, RL, Trehan, AK, Pearce, BC, Yin, Z, Combrink, KD, Gulgeze, HB, Wang, XA, Kadow, KF, Cianci, CW, Krystal, M, and Meanwell, NA
Bioorg Med Chem Lett 2004. 14(5): 1133-7
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14980651&dopt=abstract
13. 5686 DMID-LS-61; PUBMED-DMID-3/2/2004
Spirobipyridopyrans, spirobinaphthopyrans, indolinospiropyridopyrans, indolinospironaphthopyrans and indolinospironaphtho-1,4-oxazines: synthesis, study of X-ray crystal structure, antitumoral and antiviral evaluation
Raic-Malic, S, Tomaskovic, L, Mrvos-Sermek, D, Prugovecki, B, Cetina, M, Grdisa, M, Pavelic, K, Mannschreck, A, Balzarini, J, De Clercq, E, and Mintas, M
Bioorg Med Chem 2004. 12(5): 1037-45
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14980617&dopt=abstract
14. 5687 DMID-LS-61; PUBMED-DMID-3/2/2004
TFIIH Transcription Factor, a Target for the Rift Valley Hemorrhagic Fever Virus
Le May, N, DubaeLe S, De Santis, LP, Billecocq, A, Bouloy, M, and Egly, JM
Cell 2004. 116(4): 541-50
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14980221&dopt=abstract
15. 5688 DMID-LS-61; PUBMED-DMID-3/2/2004
Human herpesvirus 6 (HHV6) infection
Abdel-Haq, NM and Asmar, BI
Indian J Pediatr 2004. 71(1): 89-96
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14979393&dopt=abstract
16. 5689 DMID-LS-61; PUBMED-DMID-3/2/2004
Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection
Shen, Y, Zhukovskaya, NL, Zimmer, MI, Soelaiman, S, Bergson, P, Wang, CR, Gibbs, CS, and Tang, WJ
Proc Natl Acad Sci U S A 2004
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14978283&dopt=abstract
17. 5690 DMID-LS-61; PUBMED-DMID-3/2/2004
Alternatively spliced soluble coxsackie- adenovirus receptors inhibit coxsackievirus infection
Dorner, A, Xiong, D, Couch, K, Yajima, T, and Knowlton, KU
J Biol Chem 2004
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14978041&dopt=abstract
18. 5691 DMID-LS-61; PUBMED-DMID-3/2/2004
Severe acute respiratory syndrome (SARS) - an emerging infection of the 21st century
Hsueh, PR and Yang, PC
J Formos Med Assoc 2003. 102(12): 825-39
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14976561&dopt=abstract
19. 5692 DMID-LS-61; WOS-DMID-3/2/2004
Synthesis of Aldehydo-Sugar Derivatives of Pyrazoloquinoline as Inhibitors of Herpes Simplex Virus Type 1 Replication
Bekhit, AA, El-Sayed, OA, Aboul-Enein, HY, Siddiqui, YM, and Al-Ahdal, MN
Journal of Enzyme Inhibition and Medicinal Chemistry 2004. 19(1): 33-38
20. 5693 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Preparation of bicyclo[4.2.1]nonane nucleoside analogs for the treatment of Flaviviridae infections ((Pharmasset, Ltd. Barbados)
Wang, Peiyuan, Stuyver, Lieven J, Watanabe, Kyoichi A, Hassan, Abdalla, Chun, Byoung-Known, and Hollecker, Laurent
PATENT: WO 2004013300 A2; ISSUE DATE: 20040212
APPLICATION: 2003; PP: 147 pp.
21. 5694 DMID-LS-61; PUBMED-DMID-3/2/2004
Efficacy and duration of immunity of a combined equine influenza and equine herpesvirus vaccine against challenge with an American-like equine influenza virus (A/equi-2/Kentucky/95)
Heldens, JG, Pouwels, HG, and Van Loon, AA
Vet J 2004. 167(2): 150-7
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14975389&dopt=abstract
22. 5695 DMID-LS-61; SCIFINDER-DMID-3/2/2004
2',3'-dideoxynucleoside analogs for the treatment or prevention of flaviviridae infections((Pharmasset Ltd., Barbados, Emory University, and Board of Trustees of the Leland Stanford Junior University))
Shi, Junxing, Schinazi, Raymond F, and Striker, Robert
PATENT: WO 2004013298 A2; ISSUE DATE: 20040212
APPLICATION: 2003; PP: 86 pp.
23. 5696 DMID-LS-61; PUBMED-DMID-3/2/2004
Pharmacokinetics and safety of viramidine, a prodrug of ribavirin, in healthy volunteers
Lin, CC, Philips, L, Xu, C, and Yeh, LT
J Clin Pharmacol 2004. 44(3): 265-75
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14973309&dopt=abstract
24. 5697 DMID-LS-61; WOS-DMID-3/2/2004
Telbivudine. Anti-Hbv Agent
Sorbera, LA, Castaner, J, Castaner, RM, and Bayes, M
Drugs of the Future 2003. 28(9): 870-879
25. 5698 DMID-LS-61; PUBMED-DMID-3/2/2004
Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model
Buller, RM, Owens, G, Schriewer, J, Melman, L, BeadLe JR, and Hostetler, KY
Virology 2004. 318(2): 474-81
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14972516&dopt=abstract
26. 5699 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Preparation of cyanothiazolylpyrrolidinecarboxylates and related compounds as antivirals((Glaxo Group Limited, UK)
Burton, George, Goodland, Helen Susanne, Haigh, David, Kiesow, Terence John, Ku, Thomas W, and Slater, Martin John
PATENT: WO 2004009543 A2; ISSUE DATE: 20040129
APPLICATION: 2003; PP: 27 pp.
27. 5700 DMID-LS-61; PUBMED-DMID-3/2/2004
Sabadinine: A Potential Non-Peptide Anti-Severe Acute-Respiratory-Syndrome Agent Identified Using Structure-Aided Design
Toney, JH, Navas-Martin, S, Weiss, SR, and Koeller, A
J Med Chem 2004. 47(5): 1079-1080
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14971887&dopt=abstract
28. 5701 DMID-LS-61; PUBMED-DMID-3/2/2004
Mechanism of antiviral activities of 3'-substituted L-nucleosides against 3TC-resistant HBV polymerase: a molecular modelling approach
Chong, Y, Stuyver, L, Otto, MJ, Schinazi, RF, and Chu, CK
Antivir Chem Chemother 2003. 14(6): 309-19
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14968937&dopt=abstract
29. 5702 DMID-LS-61; PUBMED-DMID-3/2/2004
Development of new antivirals for herpesviruses
Eizuru, Y
Antivir Chem Chemother 2003. 14(6): 299-308
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14968936&dopt=abstract
30. 5703 DMID-LS-61; WOS-DMID-3/2/2004
Prospects for Antiviral Ribozymes and Deoxyribozymes
Peracchi, A
Reviews in Medical Virology 2004. 14(1): 47-64
31. 5704 DMID-LS-61; WOS-DMID-3/2/2004
Dramatic Effects of 2-Bromo-5,6-Dichloro-1-Beta-D-Ribofuranosyl Benzimidazole Riboside on the Genome Structure, Packaging, and Egress of Guinea Pig Cytomegalovirus
Nixon, DE and Mcvoy, MA
Journal of Virology 2004. 78(4): 1623-1635
32. 5705 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Method for screening EBNA-1 inhibitors, and use in the treatment of latent Epstein-Barr virus infections ((Fujisawa Pharmaceutical Co., Ltd. Japan)
Yanagi, Kazuo and Itou, Sayuri
PATENT: WO 2004008152 A1; ISSUE DATE: 20040122
APPLICATION: 2003; PP: 34 pp.
33. 5706 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Preparation of 2-amino-9-(2-hydroxymethylcyclopropylidenemethyl)-purines as antiviral agents((Wayne State University, USA and The Regents of the University of Michigan))
Zemlicka, Jiri and Drach, John C
PATENT: WO 2004006867 A2; ISSUE DATE: 20040122
APPLICATION: 2003; PP: 36 pp.
34. 5707 DMID-LS-61; PUBMED-DMID-3/2/2004
Role of indoleamine-2,3-dioxygenase in alpha/beta and gamma interferon-mediated antiviral effects against herpes simplex virus infections
Adams, O, Besken, K, Oberdorfer, C, MacKenzie, CR, Takikawa, O, and Daubener, W
J Virol 2004. 78(5): 2632-2636
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14963171&dopt=abstract
35. 5708 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Pyrimidones with antiviral properties ((Axxima Pharmaceuticals Aktiengesellschaft, Germany and 4SC AG))
Missio, Andrea, Herget, Thomas, Aschenbrenner, Andrea, Kramer, Bernd, Leban, Johann, and Wolf, Kristina
PATENT: EP 1389461 A1; ISSUE DATE: 20040218
APPLICATION: 2002-18357; PP: 46 pp.
36. 5709 DMID-LS-61; PUBMED-DMID-3/2/2004
The matrix protein of Marburg virus is transported to the plasma membrane along cellular membranes: exploiting the retrograde late endosomal pathway
Kolesnikova, L, Bamberg, S, Berghofer, B, and Becker, S
J Virol 2004. 78(5): 2382-93
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14963134&dopt=abstract
37. 5710 DMID-LS-61; WOS-DMID-3/2/2004
Hydroxymethyl-Glutaryl Coenzyme a Reductase Inhibition Limits Cytomegalovirus Infection in Human Endothelial Cells
Potena, L, Frascaroli, G, Grigioni, F, Lazzarotto, T, Magnani, G, Tomasi, L, Coccolo, F, Gabrielli, L, Magelli, C, Landini, MP, and Branzi, A
Circulation 2004. 109(4): 532-536
38. 5711 DMID-LS-61; PUBMED-DMID-3/2/2004
The nsp9 Replicase Protein of SARS-Coronavirus, Structure and Functional Insights
Sutton, G, Fry, E, Carter, L, Sainsbury, S, Walter, T, Nettleship, J, Berrow, N, Owens, R, Gilbert, R, Davidson, A, Siddell, S, Poon, LL, Diprose, J, Alderton, D, Walsh, M, Grimes, JM, and Stuart, DI
Structure (Camb) 2004. 12(2): 341-53
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14962394&dopt=abstract
39. 5712 DMID-LS-61; PUBMED-DMID-3/2/2004
West Nile Virus inactivation by the solvent/detergent steps of the second and third generation manufacturing processes for B-domain deleted recombinant factor VIII
Jakubik, JJ, Vicik, SM, Tannatt, MM, and Kelley, BD
Haemophilia 2004. 10(1): 69-74
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14962223&dopt=abstract
40. 5713 DMID-LS-61; PUBMED-DMID-3/2/2004
Stacking up the armory against viruses
Klebl, BM
Drug Discov Today 2004. 9(4): 162-4
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14960395&dopt=abstract
41. 5714 DMID-LS-61; WOS-DMID-3/2/2004
Albumin Nanoparticles Improved the Stability, Nuclear Accumulation and Anticytomegaloviral Activity of a Phosphodiester Oligonucleotide
Arnedo, A, Irache, JM, Merodio, M, and Millan, MSE
Journal of Controlled Release 2004. 94(1): 217-227
42. 5715 DMID-LS-61; PUBMED-DMID-3/2/2004
Severe acute respiratory syndrome: developing a research response
La Montagne, JR, Simonsen, L, Taylor, RJ, and Turnbull, J
J Infect Dis 2004. 189(4): 634-41
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14767816&dopt=abstract
43. 5716 DMID-LS-61; WOS-DMID-3/2/2004
Genetic Resistance to Flaviviruses
Brinton, MA and Perelygin, AA
Advances in Virus Research. 60: 43-85
44. 5717 DMID-LS-61; WOS-DMID-3/2/2004
Emtricitabine: a New Nucleoside Analogue for Once-Daily Antiretroviral Therapy
Cahn, P
Expert Opinion on Investigational Drugs 2004. 13(1): 55-68
45. 5718 DMID-LS-61; PUBMED-DMID-3/2/2004
In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: Structural analysis indicates different resistance mechanisms
Lin, C, Lin, K, Luong, YP, Rao, BG, Wei, YY, Brennan, DL, Fulghum, JR, Hsiao, HM, Ma, S, Maxwell, JP, Cottrell, KM, Perni, RB, Gates, CA, and Kwong, AD
J Biol Chem 2004
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14766754&dopt=abstract
46. 5719 DMID-LS-61; PUBMED-DMID-3/2/2004
Genotyping anti-hepatitis B virus drug resistance
Bourne, EJ, Gauthier, J, Lopez, VA, and Condreay, LD
Methods Mol Med 2004. 96: 379-386
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14762283&dopt=abstract
47. 5720 DMID-LS-61; PUBMED-DMID-3/2/2004
Ebola vaccines tested in humans, monkeys
Vastag, B
JAMA 2004. 291(5): 549-50
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14762022&dopt=abstract
48. 5721 DMID-LS-61; PUBMED-DMID-3/2/2004
The potentiating effect of ribavirin on interferon in the treatment of hepatitis C: lack of evidence for ribavirin-induced viral mutagenesis
Schinkel, J, De Jong, MD, Bruning, B, Van Hoek, B, Spaan, WJ, and Kroes, AC
Antivir Ther 2003. 8(6): 535-40
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14760887&dopt=abstract
49. 5722 DMID-LS-61; PUBMED-DMID-3/2/2004
Inhibition of glycogen breakdown by imino sugars in vitro and in vivo
Andersson, U, Reinkensmeier, G, Butters, TD, Dwek, RA, and Platt, FM
Biochem Pharmacol 2004. 67(4): 697-705
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14757169&dopt=abstract
50. 5723 DMID-LS-61; WOS-DMID-3/2/2004
Human Cytomegalovirus Elicits a Coordinated Cellular Antiviral Response Via Envelope Glycoprotein B
Boehme, KW, Singh, J, Perry, ST, and Compton, T
Journal of Virology 2004. 78(3): 1202-1211
51. 5724 DMID-LS-61; PUBMED-DMID-3/2/2004
Smallpox: clinical features, prevention, and management
Guharoy, R, Panzik, R, Noviasky, JA, Krenzelok, EP, and Blair, DC
Ann Pharmacother 2004. 38(3): 440-7
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14755066&dopt=abstract
52. 5725 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Small interfering RNAs with backbone or base modifications directed against hepatitis C virus and their use in treatment of infection ((Chiron Corporation, USA)
Han, Jang, Seo, Mi Young, and Houghton, Michael
PATENT: WO 2004011647 A1; ISSUE DATE: 20040205
APPLICATION: 2003; PP: 74 pp.
53. 5726 DMID-LS-61; WOS-DMID-3/2/2004
Two New Bicoumarins From Clausena Excavata
Takemura, Y, Kanao, K, Konoshima, A, Ju-Ichi, M, Ito, C, Furukawa, H, Tokuda, H, and Nishino, H
Heterocycles 2004. 63(1): 115-+
54. 5727 DMID-LS-61; SCIFINDER-DMID-3/2/2004
The DNA-binding domain of human papillomavirus type 18 E1: Crystal structure, dimerization, and DNA binding
Auster, Anitra S and Joshua-Tor, Leemor
Journal of Biological Chemistry 2004. 279(5): 3733-3742
55. 5728 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Rapid-acting broad spectrum protection against biological threat agents((USA))
Alibek, Ken, Bailey, Charles, Carron, Edith Grene, Popov, Serguei G, Wu, Aiguo G, Popova, Taissia, Klotz, Francis W, Hayford, Alice, Karginov, Vladimir, Zhai, Qingzhu, and Liu, Ge
PATENT: US 2004018193 A1; ISSUE DATE: 20040129
APPLICATION: 2003-6846; PP: 58 pp.
56. 5729 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Nucleotides, preparation thereof and use as antiviral agents and inhibitors of RNA viral polymerases ((Biocryst Pharmaceuticals, Inc. USA)
Babu, Yarlagadda S, Chand, Pooran, El-Kattan, Yahya, and Wu, Minwan
PATENT: US 2004014722 A1; ISSUE DATE: 20040122
APPLICATION: 2003-43963; PP: 22 pp., Cont.-in-part of Appl. No. PCT/US02-36621.
57. 5730 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Phosphonate nucleotide and thiadiazole compounds for the treatment of smallpox((USA))
Colacino, Joseph Matthew
PATENT: US 2004023928 A1; ISSUE DATE: 20040205
APPLICATION: 2002-11665; PP: 3 pp.
58. 5731 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Systemic administration of NAC as an adjunct in the treatment of bioterror exposures such as anthrax, smallpox or radiation and for vaccination prophylaxis, and use in combination with DHEA for the treatment of smallpox and other viruses((USA))
Guilford, FTimothy and Schumm, Brooke
PATENT: US 2004022873 A1; ISSUE DATE: 20040205
APPLICATION: 2002-27790; PP: 15 pp., Cont.-in-part of U.S. Provisional Ser. No. 371,590.
59. 5732 DMID-LS-61; WOS-DMID-3/2/2004
Established and Potential Strategies Against Papillomavirus Infections
Bernard, HU
Journal of Antimicrobial Chemotherapy 2004. 53(2): 137-139
60. 5733 DMID-LS-61; WOS-DMID-3/2/2004
Polio Control After Certification: Major Issues Outstanding
Fine, PEM, Oblapenko, G, and Sutter, RW
Bulletin of the World Health Organization 2004. 82(1): 47-52
61. 5734 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Combination therapy with 1,3-dioxolanes and inosine monophosphate dehydrogenase inhibitors((Triangle Pharmaceuticals, Inc. USA )
Furman, Phillip A and Borroto-Esoda, Katyna
PATENT: WO 2004009595 A1; ISSUE DATE: 20040129
APPLICATION: 2003; PP: 91 pp.
62. 5735 DMID-LS-61; WOS-DMID-3/2/2004
Will Containment of Wild Poliovirus in Laboratories and, Inactivated Poliovirus Vaccine Production Sites Be Effective for Global Certification?
DowdLe WR, Wolff, C, Sanders, R, Lambert, S, and Best, M
Bulletin of the World Health Organization 2004. 82(1): 59-62
63. 5736 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Pharmaceutical compositions comprising hepatitis C viral protease inhibitors((Boehringer Ingelheim Pharmaceuticals, Inc. USA)
Chen, Shirlynn and Mei, Xiaohui
PATENT: WO 2004009121 A1; ISSUE DATE: 20040129
APPLICATION: 2003; PP: 66 pp.
64. 5737 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Thionucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase((Merck & Co., Inc. USA and Isis Pharmaceuticals, Inc.)
Olsen, David B, Bhat, Balkrishen, and Cook, Phillip Dan
PATENT: WO 2004009020 A2; ISSUE DATE: 20040129
APPLICATION: 2003; PP: 48 pp.
65. 5738 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Chimeric GB virus B (GBV-B) containing partial HCV 5'-NTR as persistent infectious surrogate viruses or a model for HCV vaccine development and drug screening((Board of Regents, the University of Texas System USA and Institut Pasteur))
Martin, Annette, Sangar, David V, Lemon, Stanley M, and Rijnbrand, Rene
PATENT: WO 2004005498 A1; ISSUE DATE: 20040115
APPLICATION: 2003; PP: 108 pp.
66. 5739 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Preparation of N-alkenyl carboxamide inhibitors of HCV NS5b polymerase for treating hepatitis C viral infections and associated diseases((Pharmacia & Upjohn Company, USA and Finzel, Barry C.)
Gao, Hua, Greene, Meredith L, Gross, Rebecca J, Nugent, Richard A, and Pfefferkorn, Jeffrey
PATENT: WO 2004002977 A1; ISSUE DATE: 20040108
APPLICATION: 2003; PP: 186 pp.
67. 5740 DMID-LS-61; WOS-DMID-3/2/2004
Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice With Ether Lipid Esters of Cidofovir
Quenelle DC, Collins, DJ, Wan, WB, BeadLe JR, Hostetler, KY, and Kern, ER
Antimicrobial Agents and Chemotherapy 2004. 48(2): 404-412
68. 5741 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Preparation of N-(phenylaminophenyl)carboxamide and related compound inhibitors of HCV NS5b polymerase for treating hepatitis C viral infections and associated diseases((Pharmacia & Upjohn Company, USA)
Finzel, Barry C, Funk, Lee A, Kelly, Robert C, Reding, Matthew T, and Wicnienski, Nancy Anne
PATENT: WO 2004002944 A1; ISSUE DATE: 20040108
APPLICATION: 2003; PP: 45 pp.
69. 5742 DMID-LS-61; SCIFINDER-DMID-3/2/2004
The hepatitis C virus replicase: Insights into RNA-dependent RNA replication and prospects for rational drug design
Frick, David N
Current Organic Chemistry 2004. 8(3): 223-241
70. 5743 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Method for inducing complete hepatitis C virus (HCV) replication in vitro((McGill University, Can.)
Sonenberg, Nahum and Lopez-Lastra, Marcelo
PATENT: WO 2004013318 A1; ISSUE DATE: 20040212
APPLICATION: 2003; PP: 124 pp.
71. 5744 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Inhibition of the subgenomic hepatitis C virus replicon in Huh-7 cells by 2'-deoxy-2'-fluorocytidine
Stuyver, Lieven J, McBrayer, Tamara R, Whitaker, Tony, Tharnish, Phillip M, Ramesh, Mangala, Lostia, Stefania, Cartee, Leanne, Shi, Junxing, Hobbs, Ann, Schinazi, Raymond F, Watanabe, Kyoichi A, and Otto, Michael J
Antimicrobial Agents and Chemotherapy 2004. 48(2): 651-654
72. 5745 DMID-LS-61; SCIFINDER-DMID-3/2/2004
Anti-viral 7-deaza D-nucleosides for HBV infection therapy((Micrologix Biotech Inc., Can.)
Mekouar, Khalid and Deziel, Robert
PATENT: WO 2004011478 A2; ISSUE DATE: 20040205
APPLICATION: 2003; PP: 36 pp.