NIAID Banner Logo Image


1. 45079 HIV-LS-319; PUBMED-HIV-4/5/2005

Synthesis of 2',3'-Dideoxynucleoside 5'-alpha-P-Borano-beta,gamma-(difluoromethylene)triphosphates and Their Inhibition of HIV-1 Reverse Transcriptase

Boyle, NA, Rajwanshi, VK, Prhavc, M, Wang, G, Fagan, P, Chen, F, Ewing, GJ, Brooks, JL, Hurd, T, Leeds, JM, Bruice, TW, and Cook, PD

J Med Chem 2005. 48(7): 2695-2700


2. 45080 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Selective Small Molecules Blocking HIV-1 Tat and Coactivator PCAF Association

Zeng, Lei, Li, Jiaming, Muller, Michaela, Yan, Sherry, Mujtaba, Shiraz, Pan, Chongfeng, Wang, Zhiyong, and Zhou, Ming-Ming

Journal of the American Chemical Society 2005. 127(8): 2376-2377

3. 45081 HIV-LS-319; PUBMED-HIV-4/5/2005

Simple and Simultaneous Determination of the HIV-Protease Inhibitors Amprenavir, Atazanavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir and Saquinavir Plus M8 Nelfinavir Metabolite and the Nonnucleoside Reverse Transcriptase Inhibitors Efavirenz and Nevirapine in Human Plasma by Reversed-Phase Liquid Chromatography

Poirier, JM, Robidou, P, and Jaillon, P

Ther Drug Monit 2005. 27(2): 186-192


4. 45082 HIV-LS-319; PUBMED-HIV-4/5/2005

Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase

Oz-Gleenberg, I, Avidan, O, Goldgur, Y, Herschhorn, A, and Hizi, A

J Biol Chem 2005.


5. 45083 HIV-LS-319; PUBMED-HIV-4/5/2005

The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro

Lorin, C, Saidi, H, Belaid, A, Zairi, A, Baleux, F, Hocini, H, Belec, L, Hani, K, and Tangy, F

Virology 2005. 334(2): 264-275


6. 45084 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Synthesis and Evaluation of Double-Prodrugs against HIV. Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-Type Reverse Transcriptase Inhibitors via the SATE Prodrug Approach

Petersen, Lene, Jorgensen, Per T, Nielsen, Claus, Hansen, Thomas H, Nielsen, John, and Pedersen, Erik B

Journal of Medicinal Chemistry 2005. 48(4): 1211-1220

7. 45085 HIV-LS-319; PUBMED-HIV-4/5/2005

4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV Mutant Strains

Benjahad, A, Croisy, M, Monneret, C, Bisagni, E, Mabire, D, Coupa, S, Poncelet, A, Csoka, I, Guillemont, J, Meyer, C, Andries, K, Pauwels, R, de, Bethune MP, Himmel, DM, Das, K, Arnold, E, Nguyen, CH, and Grierson, DS

J Med Chem 2005. 48(6): 1948-1964


8. 45086 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Identification of authentic inhibitors of HIV-1 integration

Witvrouw, M, Fikkert, V, Vercammen, J, Van Maele, B, Engelborghs, Y, and Debyser, Z

Current Medicinal Chemistry: Anti-Infective Agents 2005. 4(2): 153-165

9. 45087 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Hiv protease inhibitors, compositions containing the same and their pharmaceutical uses

Alegria, Larry Andrew, Dress, Klaus Ruprecht, Huang, Buwen, Kumpf, Robert Arnold, Lewis, Kathleen Kingsley, Matthews, Jean Joo, Sakata, Sylvie Kim, and Wallace, Michael Brennan

PATENT: WO 2005026114 ISSUE DATE: 20050324


ASSIGNEE: (Pfizer Inc., USA

10. 45088 HIV-LS-319; SCIFINDER-HIV-3/29/2005

The Novel L- and D-Amino Acid Derivatives of Hydroxyurea and Hydantoins: Synthesis, X-ray Crystal Structure Study, and Cytostatic and Antiviral Activity Evaluations

Opacic, Ninoslav, Barbaric, Monika, Zorc, Branka, Cetina, Mario, Nagl, Ante, Frkovic, Danijel, Kralj, Marijeta, Pavelic, Kresimir, Balzarini, Jan, Andrei, Graciela, Snoeck, Robert, De Clercq, Erik, Raic-Malic, Silvana, and Mintas, Mladen

Journal of Medicinal Chemistry 2005. 48(2): 475-482

11. 45089 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Synthesis and antiviral activity of novel 4',5'-branched pyrimidine nucleosides

Kim, Aihong, Kooh, Dae-Ho, Ko, Ok Hyun, and Hong, Joon Hee

Yakhak Hoechi 2005. 49(1): 20-24

12. 45090 HIV-LS-319; PUBMED-HIV-4/5/2005

Nuclear translocation as a novel target for anti-HIV drugs

Haffar, O and Bukrinsky, M

Expert Rev Anti Infect Ther 2005. 3(1): 41-50


13. 45091 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Compositions and methods for use of antiviral drugs in the treatment of retroviral diseases resistant to nucleoside reverse transcriptase inhibitors

Parniak, Michael, Mellors, John W, Oldfield, Eric, Tovian, Zev, and Chan, Julian Mun Weng

PATENT: WO 2005023270 ISSUE DATE: 20050317

APPLICATION: 2004 PP: 50 pp.

ASSIGNEE: (University of Pittsburgh-of the Commonwealth System of Higher Education, USA and University of Illinois)

14. 45092 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Combinations of pyrimidine-containing nonnucleoside reverse transcriptase inhibitor (NNRTI) TMC278 with reverse transcriptase inhibitors for the treatment of HIV infection

Stoffels, Paul

PATENT: WO 2005021001 ISSUE DATE: 20050310

APPLICATION: 2004 PP: 34 pp.

ASSIGNEE: (Tibotec Pharmaceuticals Ltd., Ire.

15. 45093 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Structure activity relationship of disulfone-containing HIV-1 integrase inhibitors

Meadows, DChristopher, Gervay-Hague, Jacquelyn, Matthews, Timothy B, and North, Thomas W

229th ACS National Meeting 2005. 229: MEDI-338

16. 45094 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Discovery of the piperidine-4-carboxamide derivative TAK-220, a highly potent CCR5 antagonist anti-HIV-1 agent

Imamura, Shinichi, Ichikawa, Takashi, Nishikawa, Youichi, Hashiguchi, Shohei, Kanzaki, Naoyuki, Takashima, Katsunori, Niwa, Shinichi, Yamamoto, Yoshio, Baba, Masanori, and Sugihara, Yoshihiro

229th ACS National Meeting 2005. 229: MEDI-090

17. 45095 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Structural and Functional Modeling of Human Lysozyme Reveals a Unique Nonapeptide, HL9, with Anti-HIV Activity

Lee-Huang, Sylvia, Maiorov, Vladimir, Huang, Philip L, Ng, Angela, Lee, Hee Chul, Chang, Young-Tae, Kallenbach, Neville, Huang, Paul L, and Chen, Hao-Chia

Biochemistry 2005. 44(12): 4648-4655

18. 45096 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors

Robinson, WEdward, King, Peter J, and Reinecke, Manfred G

PATENT: US 20050049242 ISSUE DATE: 20050303

APPLICATION: 2003-17364 PP: 32 pp., Cont. of U.S. Ser. No. 647,270, abandoned.


19. 45097 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Preparation of pyrido[1,2-a]pyrazine-1,8-dione derivatives as HIV integrase inhibitors

Miyazaki, Susumu, Katoh, Susumu, Adachi, Kaoru, Isoshima, Hirotaka, Kobayashi, Satoru, Matsuzaki, Yuji, Watanabe, Wataru, Yamataka, Kazunobu, Kiyonari, Shinichi, and Wamaki, Shuichi

PATENT: WO 2005016927 ISSUE DATE: 20050224

APPLICATION: 2004 PP: 355 pp.

ASSIGNEE: (Japan Tobacco Inc., Japan

20. 45098 HIV-LS-319; SCIFINDER-HIV-3/29/2005

Topological models for the prediction of anti-HIV activity of dihydro (alkylthio) (naphthylmethyl) oxopyrimidines

Lather, Viney and Madan, AK

Bioorganic & Medicinal Chemistry 2005. 13(5): 1599-1604

21. 45099 HIV-LS-319; WOS-HIV-3/27/2005

Exploring the stereochemical requirements for protease inhibition by ureidopeptides

Barth, BS, Myers, AC, and Lipton, MA

JOURNAL OF PEPTIDE RESEARCH 2005. 65(3): 352-354, 3


22. 45100 HIV-LS-319; WOS-HIV-3/27/2005

HIV-1 Vif can directly inhibit apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G-mediated cytidine deamination by using a single amino acid interaction and without protein degradation

Santa-Marta, M, da, Silva FA, Fonseca, AM, and Goncalves, J

JOURNAL OF BIOLOGICAL CHEMISTRY 2005. 280(10): 8765-8775, 11


23. 45101 HIV-LS-319; WOS-HIV-3/27/2005

Racemic and enantioselective synthesis of enol-lactone and their biological activity as potent HIV-1 protease inhibitors

Ibrahimi, S, Sauve, G, Yelle, J, and Essassi, E

COMPTES RENDUS CHIMIE 2005. 8(1): 75-83, 9


24. 45102 HIV-LS-319; WOS-HIV-3/27/2005

Synthesis of racemic 9-(6-and 2,6-substituted 9H-purin-9-yl)-5-oxatricyclo[,7)]non ne-3-methanols, novel conformationally locked carbocyclic nucleosides

Hrebabecky, H, Masojidkova, M, and Holy, A



25. 45103 HIV-LS-319; WOS-HIV-3/27/2005

A novel synthetic chemokine containing D-amino acids that binds to the CXCR4 receptor and inhibits HIV-1 infection

Huang, ZW, Liu, DX, Madani, N, Kumar, S, Choi, WT, Cao, R, Li, Y, Gao, YG, Dong, CZ, Wang, J, An, J, and Sodroski, JG

BLOOD 2004. 104(11): 174A-1


26. 45104 HIV-LS-319; WOS-HIV-4/3/2005

Plant based HIV-1 vaccine candidate: Tat protein produced in spinach

Karasev, AV, Foulke, S, Wellens, C, Rich, A, Shon, KJ, Zwierzynski, I, Hone, D, Koprowski, H, and Reitz, M

VACCINE 2005. 23(15): 1875-1880, 6


27. 45105 HIV-LS-319; WOS-HIV-4/3/2005

HIV-1 replication inhibitors of the styrylquinoline class: introduction of an additional carboxyl group at the C-5 position of the quinoline

Zouhiri, F, Danet, M, Benard, C, Normand-Bayle, M, Mouscadet, JF, Leh, H, Thomas, CM, Mbemba, G, d'Angelo, J, and Desmaele, D

TETRAHEDRON LETTERS 2005. 46(13): 2201-2205, 5


If using ChemDB information for publication or abstract presentation, please cite the website in addition to the original information source.    Database last updated: May 2024