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1. 45215 HIV-LS-321; PUBMED-HIV-5/2/2005

Discovery of Small-Molecule Human Immunodeficiency Virus Type 1 Entry Inhibitors That Target the gp120-Binding Domain of CD4

Yang, QE, Stephen, AG, Adelsberger, JW , Roberts, PE, Zhu, W, Currens, MJ, Feng, Y, Crise, BJ, Gorelick, RJ, Rein, AR, Fisher, RJ, Shoemaker, RH, and Sei, S

J Virol 2005 . 79(10): 6122-6133


2. 45216 HIV-LS-321; PUBMED-HIV-5/2/2005

Anti-HIV Protease Activity from Rosa Family Plant Extracts and Rosamultin from Rosa rugosa

Park, JC, Kim, SC, Choi, MR, Song, SH, Yoo, EJ, Kim, SH, Miyashiro, H, and Hattori, M

J Med Food 2005. 8(1): 107-109


3. 45217 HIV-LS-321; PUBMED-HIV-5/2/2005

Targeting tn5 transposase identifies human immunodeficiency virus type 1 inhibitors

Ason, B, Knauss, DJ, Balke, AM, Merkel, G, Skalka, AM, and Reznikoff, WS

Antimicrob Agents Chemother 2005. 49(5): 2035-2043


4. 45218 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Preparation of 2-aminobenzimidazoles for the treatment of HIV/AIDS

Schohe-Loop, Rudolf, Paessens, Arnold, Bauser, Marcus, Koebberling, Johannes, Dittmer, Frank, Henninger, Kerstin, Lang, Dieter, and Paulsen, Daniela

PATENT: WO 2005019186 ISSUE DATE: 20050303

APPLICATION: 2004 PP: 59 pp.

ASSIGNEE: (Bayer Healthcare A.-G., Germany

5. 45219 HIV-LS-321; PUBMED-HIV-5/2/2005

Novel human immunodeficiency virus type 1 protease mutations potentially involved in resistance to protease inhibitors

Svicher, V, Ceccherini-Silberstein, F, Erba, F, Santoro, M, Gori, C, Bellocchi, MC, Giannella, S, Trotta, MP, Monforte, A, Antinori, A, and Perno, CF

Antimicrob Agents Chemother 2005. 49(5): 2015-2025


6. 45220 HIV-LS-321; PUBMED-HIV-5/2/2005

Mechanism of Anti-Human Immunodeficiency Virus Activity of {beta}-D-6-Cyclopropylamino-2',3'-Didehydro-2',3'-Dideoxyguanosine

Ray, AS, Hernandez-Santiago, BI, Mathew, JS, Murakami, E, Bozeman, C, Xie, MY, Dutschman, GE, Gullen, E, Yang, Z, Hurwitz, S, Cheng, YC, Chu, CK, McClure, H, Schinazi, RF, and Anderson, KS

Antimicrob Agents Chemother 2005. 49(5): 1994-2001


7. 45221 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Preparation of 5-membered heterocycles, in particular pyrazoles and imidazoles, as p38 kinase inhibitors

Fryszman, Olga M, Lang, Hengyuan, Lan, Jiong, Chang, Edcon, and Fang, Yunfeng

PATENT: WO 2005009973 ISSUE DATE: 20050203

APPLICATION: 2004 PP: 197 pp.

ASSIGNEE: (Triad Therapeuctics, Inc. USA

8. 45222 HIV-LS-321; PUBMED-HIV-5/2/2005

Evaluation of selected South African medicinal plants for inhibitory properties against human immunodeficiency virus type 1 reverse transcriptase and integrase

Bessong, PO, Obi, CL, Andreola, ML, Rojas, LB, Pouysegu, L, Igumbor, E, Meyer, JJ, Quideau, S, and Litvak, S

J Ethnopharmacol 2005. 99(1): 83-91


9. 45223 HIV-LS-321; PUBMED-HIV-5/2/2005

Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages

Aquaro, S, Svicher, V, Ceccherini-Silberstein, F, Cenci, A, Marcuccilli, F, Giannella, S, Marcon, L, Calio, R, Balzarini, J, and Perno, CF

J Antimicrob Chemother 2005.


10. 45224 HIV-LS-321; PUBMED-HIV-5/2/2005

Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines

Nunnari, G, Argyris, E, Fang, J, Mehlman, KE, Pomerantz, RJ, and Daniel, R

Virology 2005. 335(2): 177-184


11. 45225 HIV-LS-321; PUBMED-HIV-5/2/2005

Oximinoarylsulfonamides as potent HIV protease inhibitors

Yeung, CM, Klein, LL, Flentge, CA, Randolph, JT, Zhao, C, Sun, M, Dekhtyar, T, Stoll, VS, and Kempf, DJ

Bioorg Med Chem Lett 2005. 15(9): 2275-2278


12. 45226 HIV-LS-321; PUBMED-HIV-5/2/2005

Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase

Lau, A, Swinbank, KM, Ahmed, PS, Taylor, DL, Jackson, SP, Smith, GC, and O'connor, MJ

Nat Cell Biol 2005.


13. 45227 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL

Habu, Yuichiro, Miyano-Kurosaki, Naoko, Kitano, Michiko, Endo, Yumihiko, Yukita, Masakazu, Ohira, Shigeru, Takaku, Hiroaki, Nashimoto, Masayuki, and Takaku, Hiroshi

Nucleic Acids Research 2005. 33(1): 235-243

14. 45228 HIV-LS-321; PUBMED-HIV-5/2/2005


Balzarini, J, Auxerx, J, Rodriguez-Barrios, F, Chedad, A, Farkas, V, Ceccherini-Silberstein, F, Garcia-Aparicio, C, Velazquez, S, De Clercq, E, Perno, CF, Camarasa, MJ, and Gago, F

Mol Pharmacol 2005.


15. 45229 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Essential regions for antiviral activities of actinohivin, a sugar-binding anti-human immunodeficiency virus protein from an actinomycete

Takahashi, Atsushi, Inokoshi, Junji, Chiba, Harumi, Omura, Satoshi, and Tanaka, Haruo

Archives of Biochemistry and Biophysics 2005. 437(2): 233-240

16. 45230 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Dihydropyrimidinyl and other heterocyclic compound dipeptidyl peptidase IV (DPPIV) inhibitors

Cao, Sheldon X, Feng, Jun, Gwaltney, Stephen L, Kaldor, Stephen W, Stafford, Jeffrey A, Wallace, Michael B, Xiao, Xiao-Yi, and Zhang, Zhiyuan

PATENT: WO 2005026148 ISSUE DATE: 20050324

APPLICATION: 2004 PP: 161 pp.

ASSIGNEE: (Syrrx, Inc. USA

17. 45231 HIV-LS-321; PUBMED-HIV-5/2/2005

Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction

Grainger, DJ and Lever, AM

Retrovirology 2005. 2(1): 23


18. 45232 HIV-LS-321; WOS-HIV-4/24/2005

4D-QSAR models of HOE/BAY-793 analogues as HIV-1 protease inhihitors

da Cunha, EFF, Albuquerque, MG, Antunes, OAC, and de Alencastro, RB

QSAR & COMBINATORIAL SCIENCE 2005. 24(2): 240-253, 14


19. 45233 HIV-LS-321; WOS-HIV-4/24/2005

Synthesis and biological evaluation of 2 ',3 '-didehydro-2 ', 3 '-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2 ',3 '-dideoxy-9-deazaguanosine and 2 ',3 '-didehydro-2 ',3 '-dideoxy-9-deazainosine

Liu, MC, Luo, MZ, Mozdziesz, DE, Dutschman, GE, Gullen, EA, Cheng, YC, and Sartorelli, AC



20. 45234 HIV-LS-321; SCIFINDER-HIV-4/25/2005

<04 Article Title>

Embrey, Mark W, Wai, John S, Funk, Timothy W, Homnick, Carl F, Perlow, Debbie S, Young, Steven D, Vacca, Joseph P, Hazuda, Daria J, Felock, Peter J, Stillmock, Kara A, Witmer, Marc V, Moyer, Gregory, Schleif, William A, Gabryelski, Lori J, Jin, Lixia, Chen, I-Wu, Ellis, Joan D, Wong, Bradley K, Lin, Jiunn H, Leonard, Yvonne M, Tsou, Nancy N, and Zhuang, Linghang

<10 Journal Title> 2005.(<24 Issue ID>): <25 Page(s)>

21. 45235 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Polypeptide multimers comprising coiled coil structure and a-helical structure for use as antiviral, anti-HIV and anti-SIV agents

Weiss, Carol D, He, Yong, Vassell, Russell, and De, Rosny Eve

PATENT: WO 2005018666 ISSUE DATE: 20050303

APPLICATION: 2003 PP: 84 pp.

ASSIGNEE: (The Government of the United States of America, as Represented by the Department of Health and Human Services USA and De Rosny, Eve

22. 45236 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Preparation of phenanthridine derivatives as anti-viral agents

Tor, Yitzhak and Luedtke, Nathan

PATENT: WO 2005016343 ISSUE DATE: 20050224

APPLICATION: 2004 PP: 58 pp.

ASSIGNEE: (The Regents of the University of California, USA

23. 45237 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Ex Vivo Modeling of the Effects of Mycophenolic Acid on HIV Infection: Considerations for Antiviral Therapy

Kaur, Rupinderjeet, Klichko, Vladimir, and Margolis, David

AIDS Research and Human Retroviruses 2005. 21(2): 116-124

24. 45238 HIV-LS-321; SCIFINDER-HIV-4/25/2005

A preparation of antiviral and antibacterial derivatives of dithioxopyranodipyrimidine and their 10-aza-analogs

Tets, VV, Krasnov, KA, and Ashkinazi, RI

PATENT: RU 2246496 ISSUE DATE: 20050220

APPLICATION: 2003-62807 PP: No pp. given

ASSIGNEE: (Russia)

25. 45239 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Preparation of nucleobase phosphonate analogs for antiviral treatment and as retroviral reverse transcriptase inhibitors

Krawczyk, Steven H

PATENT: WO 2005012324 ISSUE DATE: 20050210

APPLICATION: 2004 PP: 140 pp.

ASSIGNEE: (Gilead Sciences, Inc. USA

26. 45240 HIV-LS-321; SCIFINDER-HIV-4/25/2005

Trimeric Membrane-anchored gp41 Inhibits HIV Membrane Fusion

Lenz, Oliver, Dittmar, Matthias T, Wagner, Andreas, Ferko, Boris, Vorauer-Uhl, Karola, Stiegler, Gabriela, and Weissenhorn, Winfried

Journal of Biological Chemistry 2005. 280(6): 4095-4101

27. 45241 HIV-LS-321; WOS-HIV-4/24/2005

Amino acid derivatives, part 2: Synthesis, antiviral, and antitumor activity of simple protected amino acids functionalized at N-terminus with naphthalene side chain

Ali, IAI, Al-Masoudi, IA, Saeed, B, Al-Masoudi, NA, and La Colla, P

HETEROATOM CHEMISTRY 2005. 16(2): 148-155, 8


28. 45242 HIV-LS-321; WOS-HIV-4/24/2005

Synthesis and antiviral activity of some no vel isatin derivatives

Selvam, P, Rajasekaran, A, Dharamsi, A, Ahmed, KL, Musthafa, SM, Poornima, K, Pournami, KA, Murugesh, N, Chandramohan, M, and De, Clercq E

ASIAN JOURNAL OF CHEMISTRY 2005. 17(1): 443-448, 6


29. 45243 HIV-LS-321; WOS-HIV-4/24/2005

Antiviral activity of serum from the American alligator (Alligator mississippiensis)

Merchant, ME, Pallansch, M, Paulman, RL, Wells, JB, Nalca, A, and Ptak, R

ANTIVIRAL RESEARCH 2005. 66(1): 35-38, 4


30. 45244 HIV-LS-321; WOS-HIV-5/1/2005

Synthesis of 1-[2-hydroxy thoxy)methyl]-6-(5,6,7,8-tetrahydronaphthylmethyl-1) thymine as novel inhibitor against drug-resistant HIV mutants

Meng, G, Kuang, YY, Ji, L, and Chen, FE

SYNTHETIC COMMUNICATIONS 2005. 35(8): 1095-1102, 8


31. 45245 HIV-LS-321; WOS-HIV-5/1/2005

Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis

Balzarini, J, Van Laethem, K, Hatse, S , Froeyen, M, Van Damme, E, Bolmstedt, A, Peumans, W, De Clercq, E, and Schols, D

MOLECULAR PHARMACOLOGY 2005. 67(5): 1556-1565, 10


32. 45246 HIV-LS-321; WOS-HIV-5/1/2005

ATP gamma S disrupts human immunodeficiency virus type 1 virion core integrity

Gurer, C, Hoglund, A, Hoglund, S, and Luban, J

JOURNAL OF VIROLOGY 2005. 79(9): 5557-5567, 11


33. 45247 HIV-LS-321; WOS-HIV-5/1/2005

Macrophage inflammatory protein 1 alpha inhibits postentry steps of human immunodeficiency virus type 1 infection via suppression of intracellular cyclic AMP

Amella, CA, Sherry, B, Shepp, DH, and Schmidtmayerova, H

JOURNAL OF VIROLOGY 2005. 79(9): 5625-5631, 7


34. 45248 HIV-LS-321; WOS-HIV-5/1/2005

Some reactions of 3-chloroisoindolium salts with nucleophiles: access to isoindole derivatives and ellipticine analogues as potential antiviral agents

Hamed, AA



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