ONLINE DATABASE SEARCH - HIV-LS-323-MEMO
1. 45323 HIV-LS-323; PUBMED-HIV-5/31/2005
TMC114, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor Active against Protease Inhibitor-Resistant Viruses, Including a Broad Range of Clinical Isolates
De Meyer, S, Azijn, H, Surleraux, D, Jochmans, D, Tahri, A, Pauwels, R, Wigerinck, P, and de Bethune, MP
Antimicrob Agents Chemother 2005. 49(6): 2314-2321
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15917527&dopt=abstract
2. 45324 HIV-LS-323; PUBMED-HIV-5/31/2005
Structure-Based Design, Parallel Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives
Ranise, A, Spallarossa, A, Cesarini, S , Bondavalli, F, Schenone, S, Bruno, O, Menozzi, G, Fossa, P, Mosti, L, La Colla, M, Sanna, G, Murreddu, M, Collu, G, Busonera, B, Marongiu, ME, Pani, A, La Colla, P, and Loddo, R
J Med Chem 2005. 48(11): 3858-3873
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15916438&dopt=abstract
3. 45325 HIV-LS-323; PUBMED-HIV-5/31/2005
Synthesis, Antiviral Activity, and Mechanism of Drug Resistance of d- and l-2',3'-Didehydro-2',3'-dideoxy-2'-fluorocarbocyclic Nucleosides
Wang, J, Jin, Y, Rapp, KL, Bennett, M, Schinazi, RF, and Chu, CK
J Med Chem 2005. 48(11): 3736-3748
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15916425&dopt=abstract
4. 45326 HIV-LS-323; PUBMED-HIV-5/31/2005
Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis
Li, Z, Xiong, Y, Peng, Y, Pan, J, Chen, Y, Wu, X, Hussain, S, Tien, P, and Guo, D
FEBS Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15913611&dopt=abstract
5. 45327 HIV-LS-323; PUBMED-HIV-5/31/2005
Rational design of highly potent HIV-1 fusion inhibitory proteins: Implication for developing antiviral therapeutics
Ni, L, Gao, GF, and Tien, P
Biochem Biophys Res Commun 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15913557&dopt=abstract
6. 45328 HIV-LS-323; PUBMED-HIV-5/31/2005
2H-Pyrrolo[3,4-b] [1,5]benzothiazepine derivatives as potential inhibitors of HIV-1 reverse transcriptase
Di Santo, R and Costi, R
Farmaco 2005 . 60(5): 385-392
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15910811&dopt=abstract
7. 45329 HIV-LS-323; PUBMED-HIV-5/31/2005
Analogues of the styrylquinoline and styrylquinazoline HIV-1 integrase inhibitors: design and synthetic problems
Polanski, J, Niedbala, H, Musiol, R, Tabak, D, Podeszwa, B, Gieleciak, R, Bak, A, Palka, A, and Magdziarz, T
Acta Pol Pharm 2004. 61 Suppl: 3-4
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15909921&dopt=abstract
8. 45330 HIV-LS-323; PUBMED-HIV-5/31/2005
Screening of selected wood-damaging fungi for the HIV-1 reverse transcriptase inhibitors
Mlinaric, A, Kac, J, and Pohleven, F
Acta Pharm 2005. 55(1): 69-79
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15907225&dopt=abstract
9. 45331 HIV-LS-323; SCIFINDER-HIV-5/24/2005
Structure-Activity Relationship Studies of a Series of Antiviral and Antibacterial Aglycon Derivatives of the Glycopeptide Antibiotics Vancomycin, Eremomycin, and Dechloroeremomycin
Printsevskaya, Svetlana S, Solovieva, Svetlana E, Olsufyeva, Eugenia N, Mirchink, Elena P, Isakova, Elena B, De Clercq, Erik, Balzarini, Jan, and Preobrazhenskaya, Maria N
Journal of Medicinal Chemistry 2005. 48(11): 3885-3890
10. 45332 HIV-LS-323; PUBMED-HIV-5/31/2005
Inhibition of HIV-1 replication by RNA targeted against the LTR region
Puerta-Fernandez, E, Jesus, AB, Romero-Lopez, C, Tapia, N, Martinez, MA, and Berzal-Herranz, A
AIDS 2005. 19 (9): 863-870
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15905666&dopt=abstract
11. 45333 HIV-LS-323; PUBMED-HIV-5/31/2005
In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs
Uckun, FM, Qazi, S, and Venkatachalam, TK
Arzneimittelforschung 2005. 55(4): 223-231
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15901046&dopt=abstract
12. 45334 HIV-LS-323; PUBMED-HIV-5/31/2005
Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease
Sperka, T, Pitlik, J, Bagossi, P, and Tozser, J
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15893929&dopt=abstract
13. 45335 HIV-LS-323; SCIFINDER-HIV-5/24/2005
Studies on the Mechanism of Inactivation of the HIV-1 Nucleocapsid Protein NCp7 with 2-Mercaptobenzamide Thioesters
Jenkins, Lisa MMiller, Byrd, JCalvin, Hara, Toshiaki, Srivastava, Pratibha, Mazur, Sharlyn J, Stahl, Stephen J, Inman, John K, Appella, Ettore, Omichinski, James G, and Legault, Pascale
Journal of Medicinal Chemistry 2005. 48(8): 2847-2858
14. 45336 HIV-LS-323; PUBMED-HIV-5/31/2005
Synthesis of 5'-triphosphate mimics (P3Ms) of 3'-azido-3',5'-dideoxythymidine and 3',5'-dideoxy-5'-difluoromethylenethymidine as HIV-1 reverse transcriptase inhibitors
Rajwanshi, VK, Prhavc, M, Fagan, P , Brooks, JL, Hurd, T, Cook, PD, and Wang, G
Nucleosides Nucleotides Nucleic Acids 2005. 24(3): 179-189
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15892257&dopt=abstract
15. 45337 HIV-LS-323; SCIFINDER-HIV-5/24/2005
Arylsulphones: a promising class of non-nucleoside antiviral agents
Garuti, Laura, Roberti, Marinella, Pizzirani, Daniela, and Poggi, Gabriella
Current Medicinal Chemistry: Anti-Infective Agents 2005. 4(2): 167-183
16. 45338 HIV-LS-323; PUBMED-HIV-5/31/2005
KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis
Harris, KS, Brabant, W, Styrchak, S, Gall, A, and Daifuku, R
Antiviral Res 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15890415&dopt=abstract
17. 45339 HIV-LS-323; SCIFINDER-HIV-5/24/2005
Preparation of pyrrolidinecarboxamides and related carboxamides as HIV protease inhibitors for pharmaceutical use against AIDS
Alegria, Larry Andrew, Dress, Klaus Ruprecht, Huang, Buwen, Kumpf, Robert Arnold, Lewis, Kathleen Kingsley, Matthews, Jean Joo, Sakata, Sylvie Kim, and Wallace, Michael Brennan
PATENT: WO 2005026114 ISSUE DATE: 20050324
APPLICATION: 2004 PP: 159 pp.
ASSIGNEE: (Pfizer Inc., USA
18. 45340 HIV-LS-323; PUBMED-HIV-5/31/2005
Inhibition of cellular HIV-1 protease activity by LYSYL-tRNA synthetase
Guo, F, Gabor, J, Cen, S, Hu, K, Mouland, A, and Kleiman, L
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15888436&dopt=abstract
19. 45341 HIV-LS-323; PUBMED-HIV-5/31/2005
Effects of HIV Q151M-associated multi-drug resistance mutations on the activities of (-)-beta-d-1',3'-dioxolan guanine
Feng, JY, Myrick, F, Selmi, B, Deval, J, Canard, B, and Borroto-Esoda, K
Antiviral Res 2005. 66(2-3): 153-158
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15885814&dopt=abstract
20. 45342 HIV-LS-323; PUBMED-HIV-5/31/2005
Chemoenzymatic Synthesis of HIV-1 gp41 Glycopeptides: Effects of Glycosylation on the Anti-HIV Activity and alpha-Helix Bundle-Forming Ability of Peptide C34
Wang, LX, Song, H, Liu, S, Lu, H, Jiang, S, Ni, J, and Li, H
Chembiochem 2005. 6(6): 1068-1074
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15883971&dopt=abstract
21. 45343 HIV-LS-323; SCIFINDER-HIV-5/24/2005
Targeted delivery of antiviral compounds through hemoglobin bioconjugates
Adamson, JGordon, Bell, David, Ng, Nancy, and Biessels, Pieter
PATENT: US 2005059576 ISSUE DATE: 20050317
APPLICATION: 2004-60165 PP: 32 pp., Cont.-in-part of U.S. Ser. No. 231,062.
ASSIGNEE: (Can.)
22. 45344 HIV-LS-323; SCIFINDER-HIV-5/24/2005
Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor
Cianci, Christopher, Meanwell, Nicholas, and Krystal, Mark
Journal of Antimicrobial Chemotherapy 2005. 55(3): 289-292
23. 45345 HIV-LS-323; WOS-HIV-5/22/2005
Mitogen-activated protein kinases regulate LSF occupancy at the human immunodeficiency virus type 1 promoter
Ylisastigui, L, Kaur, R, Johnson, H, Volker, J, He, GC, Hansen, U, and Margolis, D
JOURNAL OF VIROLOGY 2005. 79(10): 5952-5962, 11
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228814400008
24. 45346 HIV-LS-323; WOS-HIV-5/22/2005
Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds
Tamamura, H, Araki, T, Ueda, S, Wang, ZX, Oishi, S, Esaka, A, Trent, JO, Nakashima, H, Yamamoto, N, Peiper, SC, Otaka, A, and Fujii, N
JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(9): 3280-3289, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228871700025
25. 45347 HIV-LS-323; WOS-HIV-5/22/2005
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT
Barreca, ML, Rao, A, De Luca, L, Zappala, L, Monforte, AM, Maga, G, Pannecouque, C, Balzarini, J, De Clercq, E, Chimirri, A, and Monforte, P
JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(9): 3433-3437, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228871700041
26. 45348 HIV-LS-323; WOS-HIV-5/30/2005
Convenient route to both enantiomers of a highly functionalized trans-disubstituted cyclopentene. Synthesis of the carbocyclic core of the nucleoside BCA
Banerjee, S, Ghosh, S, Sinha, S, and Ghosh, S
JOURNAL OF ORGANIC CHEMISTRY 2005. 70(10): 4199-4202, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228983300061
27. 45349 HIV-LS-323; WOS-HIV-5/30/2005
Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function
Kobayashi, M, Takaori-Kondo, A, Miyauchi, Y, Iwai, K, and Uchiyama, T
JOURNAL OF BIOLOGICAL CHEMISTRY 2005. 280(19): 18573-18578, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228932300005
28. 45350 HIV-LS-323; WOS-HIV-5/30/2005
Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection
Liu, SW, Lu, H, Neurath, AR, and Jiang, SB
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2005. 49(5): 1830-1836, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228982600024