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1. 45323 HIV-LS-323; PUBMED-HIV-5/31/2005

TMC114, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor Active against Protease Inhibitor-Resistant Viruses, Including a Broad Range of Clinical Isolates

De Meyer, S, Azijn, H, Surleraux, D, Jochmans, D, Tahri, A, Pauwels, R, Wigerinck, P, and de Bethune, MP

Antimicrob Agents Chemother 2005. 49(6): 2314-2321


2. 45324 HIV-LS-323; PUBMED-HIV-5/31/2005

Structure-Based Design, Parallel Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives

Ranise, A, Spallarossa, A, Cesarini, S , Bondavalli, F, Schenone, S, Bruno, O, Menozzi, G, Fossa, P, Mosti, L, La Colla, M, Sanna, G, Murreddu, M, Collu, G, Busonera, B, Marongiu, ME, Pani, A, La Colla, P, and Loddo, R

J Med Chem 2005. 48(11): 3858-3873


3. 45325 HIV-LS-323; PUBMED-HIV-5/31/2005

Synthesis, Antiviral Activity, and Mechanism of Drug Resistance of d- and l-2',3'-Didehydro-2',3'-dideoxy-2'-fluorocarbocyclic Nucleosides

Wang, J, Jin, Y, Rapp, KL, Bennett, M, Schinazi, RF, and Chu, CK

J Med Chem 2005. 48(11): 3736-3748


4. 45326 HIV-LS-323; PUBMED-HIV-5/31/2005

Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis

Li, Z, Xiong, Y, Peng, Y, Pan, J, Chen, Y, Wu, X, Hussain, S, Tien, P, and Guo, D

FEBS Lett 2005.


5. 45327 HIV-LS-323; PUBMED-HIV-5/31/2005

Rational design of highly potent HIV-1 fusion inhibitory proteins: Implication for developing antiviral therapeutics

Ni, L, Gao, GF, and Tien, P

Biochem Biophys Res Commun 2005.


6. 45328 HIV-LS-323; PUBMED-HIV-5/31/2005

2H-Pyrrolo[3,4-b] [1,5]benzothiazepine derivatives as potential inhibitors of HIV-1 reverse transcriptase

Di Santo, R and Costi, R

Farmaco 2005 . 60(5): 385-392


7. 45329 HIV-LS-323; PUBMED-HIV-5/31/2005

Analogues of the styrylquinoline and styrylquinazoline HIV-1 integrase inhibitors: design and synthetic problems

Polanski, J, Niedbala, H, Musiol, R, Tabak, D, Podeszwa, B, Gieleciak, R, Bak, A, Palka, A, and Magdziarz, T

Acta Pol Pharm 2004. 61 Suppl: 3-4


8. 45330 HIV-LS-323; PUBMED-HIV-5/31/2005

Screening of selected wood-damaging fungi for the HIV-1 reverse transcriptase inhibitors

Mlinaric, A, Kac, J, and Pohleven, F

Acta Pharm 2005. 55(1): 69-79


9. 45331 HIV-LS-323; SCIFINDER-HIV-5/24/2005

Structure-Activity Relationship Studies of a Series of Antiviral and Antibacterial Aglycon Derivatives of the Glycopeptide Antibiotics Vancomycin, Eremomycin, and Dechloroeremomycin

Printsevskaya, Svetlana S, Solovieva, Svetlana E, Olsufyeva, Eugenia N, Mirchink, Elena P, Isakova, Elena B, De Clercq, Erik, Balzarini, Jan, and Preobrazhenskaya, Maria N

Journal of Medicinal Chemistry 2005. 48(11): 3885-3890

10. 45332 HIV-LS-323; PUBMED-HIV-5/31/2005

Inhibition of HIV-1 replication by RNA targeted against the LTR region

Puerta-Fernandez, E, Jesus, AB, Romero-Lopez, C, Tapia, N, Martinez, MA, and Berzal-Herranz, A

AIDS 2005. 19 (9): 863-870


11. 45333 HIV-LS-323; PUBMED-HIV-5/31/2005

In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs

Uckun, FM, Qazi, S, and Venkatachalam, TK

Arzneimittelforschung 2005. 55(4): 223-231


12. 45334 HIV-LS-323; PUBMED-HIV-5/31/2005

Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease

Sperka, T, Pitlik, J, Bagossi, P, and Tozser, J

Bioorg Med Chem Lett 2005.


13. 45335 HIV-LS-323; SCIFINDER-HIV-5/24/2005

Studies on the Mechanism of Inactivation of the HIV-1 Nucleocapsid Protein NCp7 with 2-Mercaptobenzamide Thioesters

Jenkins, Lisa MMiller, Byrd, JCalvin, Hara, Toshiaki, Srivastava, Pratibha, Mazur, Sharlyn J, Stahl, Stephen J, Inman, John K, Appella, Ettore, Omichinski, James G, and Legault, Pascale

Journal of Medicinal Chemistry 2005. 48(8): 2847-2858

14. 45336 HIV-LS-323; PUBMED-HIV-5/31/2005

Synthesis of 5'-triphosphate mimics (P3Ms) of 3'-azido-3',5'-dideoxythymidine and 3',5'-dideoxy-5'-difluoromethylenethymidine as HIV-1 reverse transcriptase inhibitors

Rajwanshi, VK, Prhavc, M, Fagan, P , Brooks, JL, Hurd, T, Cook, PD, and Wang, G

Nucleosides Nucleotides Nucleic Acids 2005. 24(3): 179-189


15. 45337 HIV-LS-323; SCIFINDER-HIV-5/24/2005

Arylsulphones: a promising class of non-nucleoside antiviral agents

Garuti, Laura, Roberti, Marinella, Pizzirani, Daniela, and Poggi, Gabriella

Current Medicinal Chemistry: Anti-Infective Agents 2005. 4(2): 167-183

16. 45338 HIV-LS-323; PUBMED-HIV-5/31/2005

KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis

Harris, KS, Brabant, W, Styrchak, S, Gall, A, and Daifuku, R

Antiviral Res 2005.


17. 45339 HIV-LS-323; SCIFINDER-HIV-5/24/2005

Preparation of pyrrolidinecarboxamides and related carboxamides as HIV protease inhibitors for pharmaceutical use against AIDS

Alegria, Larry Andrew, Dress, Klaus Ruprecht, Huang, Buwen, Kumpf, Robert Arnold, Lewis, Kathleen Kingsley, Matthews, Jean Joo, Sakata, Sylvie Kim, and Wallace, Michael Brennan

PATENT: WO 2005026114 ISSUE DATE: 20050324

APPLICATION: 2004 PP: 159 pp.

ASSIGNEE: (Pfizer Inc., USA

18. 45340 HIV-LS-323; PUBMED-HIV-5/31/2005

Inhibition of cellular HIV-1 protease activity by LYSYL-tRNA synthetase

Guo, F, Gabor, J, Cen, S, Hu, K, Mouland, A, and Kleiman, L

J Biol Chem 2005.


19. 45341 HIV-LS-323; PUBMED-HIV-5/31/2005

Effects of HIV Q151M-associated multi-drug resistance mutations on the activities of (-)-beta-d-1',3'-dioxolan guanine

Feng, JY, Myrick, F, Selmi, B, Deval, J, Canard, B, and Borroto-Esoda, K

Antiviral Res 2005. 66(2-3): 153-158


20. 45342 HIV-LS-323; PUBMED-HIV-5/31/2005

Chemoenzymatic Synthesis of HIV-1 gp41 Glycopeptides: Effects of Glycosylation on the Anti-HIV Activity and alpha-Helix Bundle-Forming Ability of Peptide C34

Wang, LX, Song, H, Liu, S, Lu, H, Jiang, S, Ni, J, and Li, H

Chembiochem 2005. 6(6): 1068-1074


21. 45343 HIV-LS-323; SCIFINDER-HIV-5/24/2005

Targeted delivery of antiviral compounds through hemoglobin bioconjugates

Adamson, JGordon, Bell, David, Ng, Nancy, and Biessels, Pieter

PATENT: US 2005059576 ISSUE DATE: 20050317

APPLICATION: 2004-60165 PP: 32 pp., Cont.-in-part of U.S. Ser. No. 231,062.


22. 45344 HIV-LS-323; SCIFINDER-HIV-5/24/2005

Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor

Cianci, Christopher, Meanwell, Nicholas, and Krystal, Mark

Journal of Antimicrobial Chemotherapy 2005. 55(3): 289-292

23. 45345 HIV-LS-323; WOS-HIV-5/22/2005

Mitogen-activated protein kinases regulate LSF occupancy at the human immunodeficiency virus type 1 promoter

Ylisastigui, L, Kaur, R, Johnson, H, Volker, J, He, GC, Hansen, U, and Margolis, D

JOURNAL OF VIROLOGY 2005. 79(10): 5952-5962, 11


24. 45346 HIV-LS-323; WOS-HIV-5/22/2005

Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds

Tamamura, H, Araki, T, Ueda, S, Wang, ZX, Oishi, S, Esaka, A, Trent, JO, Nakashima, H, Yamamoto, N, Peiper, SC, Otaka, A, and Fujii, N

JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(9): 3280-3289, 10


25. 45347 HIV-LS-323; WOS-HIV-5/22/2005

Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT

Barreca, ML, Rao, A, De Luca, L, Zappala, L, Monforte, AM, Maga, G, Pannecouque, C, Balzarini, J, De Clercq, E, Chimirri, A, and Monforte, P

JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(9): 3433-3437, 5


26. 45348 HIV-LS-323; WOS-HIV-5/30/2005

Convenient route to both enantiomers of a highly functionalized trans-disubstituted cyclopentene. Synthesis of the carbocyclic core of the nucleoside BCA

Banerjee, S, Ghosh, S, Sinha, S, and Ghosh, S

JOURNAL OF ORGANIC CHEMISTRY 2005. 70(10): 4199-4202, 4


27. 45349 HIV-LS-323; WOS-HIV-5/30/2005

Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function

Kobayashi, M, Takaori-Kondo, A, Miyauchi, Y, Iwai, K, and Uchiyama, T

JOURNAL OF BIOLOGICAL CHEMISTRY 2005. 280(19): 18573-18578, 6


28. 45350 HIV-LS-323; WOS-HIV-5/30/2005

Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection

Liu, SW, Lu, H, Neurath, AR, and Jiang, SB



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