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1. 47531 HIV-LS-325; PUBMED-HIV-6/27/2005

Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors

Sherrill, RG, Furfine, ES, Hazen, RJ, Miller, JF, Reynolds, DJ, Sammond, DM, Spaltenstein, A, Wheelan, P, and Wright, LL

Bioorg Med Chem Lett 2005.


2. 47532 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Mechanistic Insights into the Suppression of Drug Resistance by Human Immunodeficiency Virus Type 1 Reverse Transcriptase Using a-Boranophosphate Nucleoside Analogs

Deval, Jerome, Alvarez, Karine, Selmi, Boulbaba, Bermond, Marielle, Boretto, Joelle, Guerreiro, Catherine, Mulard, Laurence, and Canard, Bruno

Journal of Biological Chemistry 2005. 280(5): 3838-3846

3. 47533 HIV-LS-325; PUBMED-HIV-6/27/2005

Novel 1-[2-(Diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. A Structure-Activity Relationship Investigation

De Martino, G, La Regina, G, Di, Pasquali A, Ragno, R, Bergamini, A, Ciaprini, C, Sinistro, A, Maga, G, Crespan, E , Artico, M, and Silvestri, R

J Med Chem 2005. 48(13): 4378-4388


4. 47534 HIV-LS-325; PUBMED-HIV-6/27/2005

First Synthesis and Evaluation of the Inhibitory Effects of Aza Analogues of TSAO on HIV-1 Replication

Nguyen, Van Nhien A, Tomassi, C, Len, C, Marco-Contelles, JL, Balzarini, J, Pannecouque, C, De Clercq, E, and Postel, D

J Med Chem 2005. 48(13): 4276-4284


5. 47535 HIV-LS-325; PUBMED-HIV-6/27/2005

Anti-HIV Bioactive Stilbene Dimers of Caragana rosea

Yang, GX, Zhou, JT, Li, YZ, and Hu, CQ

Planta Med 2005. 71(6): 569-71


6. 47536 HIV-LS-325; PUBMED-HIV-6/27/2005

Thiourea-based non-nucleoside inhibitors of HIV reverse transcriptase as bifunctional organocatalysts in the asymmetric Strecker synthesis

Tsogoeva, SB, Hateley, MJ, Yalalov, DA, Meindl, K, Weckbecker, C, and Huthmacher, K

Bioorg Med Chem 2005.


7. 47537 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Diazaindole-dicarbonyl-piperazinyl antiviral agents

Bender, John A, Yang, Zhong, Kadow, John F, and Meanwell, Nicholas A

PATENT: US 20050124623 ISSUE DATE: 20050609

APPLICATION: 2004-62054 PP: 87 pp.


8. 47538 HIV-LS-325; PUBMED-HIV-6/27/2005

Structure and anti-HIV activity of micrandilactones B and C, new nortriterpenoids possessing a unique skeleton from Schisandra micrantha

Li, RT, Han, QB, Zheng, YT, Wang, RR, Yang, LM, Lu, Y, Sang, SQ, Zheng, QT, Zhao, QS, and Sun, HD

Chem Commun (Camb) 2005.(23): 2936-8


9. 47539 HIV-LS-325; PUBMED-HIV-6/27/2005

In vitro HIV type 1 reverse transcriptase inhibitory activities of Thai medicinal plants and Canna indica L. rhizomes

Woradulayapinij, W, Soonthornchareonnon, N, and Wiwat, C

J Ethnopharmacol 2005.


10. 47540 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Inhibiting replication of a retrovirus, such as human immunodeficiency virus (HIV), through modulation of HIV Vif- or Vpu-mediated ubiquitylation of host cell proteins, such as CEM15 or CD4

Payan, Donald G and Jenkins, Yonchu

PATENT: WO 2005047476 ISSUE DATE: 20050526

APPLICATION: 2004 PP: 109 pp.

ASSIGNEE: (Rigel Pharmaceuticals, Inc. USA

11. 47541 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Methods and compositions for the inhibition of HIV-1 replication in hum an cells using inhibitors of p21/CDKN1A activity or gene expression, and anti-AIDS uses

Wahl, Sharon M, Vazquez-Maldonado, Nancy, and Greenwell-Wild, Teresa

PATENT: WO 2005046732 ISSUE DATE: 20050526

APPLICATION: 2004 PP: 98 pp.

ASSIGNEE: (The United Sates of America as Represented by the Secretary of Health and Human Services, NIH USA

12. 47542 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Preparation of alkylated pyrogallol calixarene type compounds as anti-viral compounds

Coveney, Donal and Costello, Benjamin

PATENT: US 20050113454 ISSUE DATE: 20050526

APPLICATION: 2003 PP: 13 pp.

ASSIGNEE: (Aids Care Pharma Limited, Ire.

13. 47543 HIV-LS-325; SCIFINDER-HIV-6/20/2005

A preparation of pyridinecarboxamide derivatives, useful for inhibiting HIV integrase

Kong, Laval Chan Chun, Zhang, Ming-Qiang, Halab, Liliane, Nguyen-Ba, Nghe, and Liu, Bingcan

PATENT: WO 2005042524 ISSUE DATE: 20050512

APPLICATION: 2004 PP: 139 pp.

ASSIGNEE: (Virochem Pharma Inc., Can.

14. 47544 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Preparation of bipiperidinyl derivatives as inhibitors of CCR5 receptors

Miller, Michael W and Scott, Jack D

PATENT: WO 2005042517 ISSUE DATE: 20050512

APPLICATION: 2004 PP: 84 pp.

ASSIGNEE: (Schering Corporation, USA

15. 47545 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Preparation of hydroxy pyridopyrrolopyrazine dione compounds useful as HIV integrase inhibitors

Wai, John S, Fisher, Thorsten E, Zhuang, Linghang, Staas, Donnette D, Lyle, Terry A, Kim, Boyoung, Embrey, Mark W, Wiscount, Catherine M, Tran, Lekhanh O, Egbertson, Melissa, and Savage, Kelly L

PATENT: WO 2005041664 ISSUE DATE: 20050512

APPLICATION: 2004 PP: 181 pp.

ASSIGNEE: (Merck & Co., Inc. USA

16. 47546 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Identification of compounds that inhibit replication of human immunodeficiency virus

Balzarini, Jan Maria Rene, Vahlne, Anders, Hogberg, Marita, and Tong, Weimin

PATENT: US 2005096319 ISSUE DATE: 20050505

APPLICATION: 92 PP: 91 pp., Cont.-in-part of U.S. Ser. No. 783,053.


17. 47547 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties

Kim, Dooseop, Wang, Liping, Hale, Jeffrey J, Lynch, Christopher L, Budhu, Richard J, MacCoss, Malcolm, Mills, Sander G, Malkowitz, Lorraine, Gould, Sandra L, DeMartino, Julie A, Springer, Martin S, Hazuda, Daria, Miller, Michael, Kessler, Joseph, Hrin, Renee C, Carver, Gwen, Carella, Anthony, Henry, Karen, Lineberger, Janet, Schleif, William A, and Emini, Emilio A

Bioorganic & Medicinal Chemistry Letters 2005. 15(8): 2129-2134

18. 47548 HIV-LS-325; WOS-HIV-6/19/2005

Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2 ',3 '-didehydro-2 ',3 '-dideoxy-2 '-fluorocarbocyclic nucleosides

Wang, JN, Jin, YH, Rapp, KL, Bennett, M, Schinazi, RF, and Chu, CK

JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(11): 3736-3748, 13


19. 47549 HIV-LS-325; WOS-HIV-6/19/2005

Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase

Gleenberg, IO, Avidan, O, Goldgur, Y, Herschhorn, A, and Hizi, A

JOURNAL OF BIOLOGICAL CHEMISTRY 2005. 280(23): 21987-21996, 10


20. 47550 HIV-LS-325; SCIFINDER-HIV-6/20/2005

Synthesis of fluoroalkyl end-capped oligomers containing pendant phosphinic and phosphonic acid segments-application to novel fluorinated bioactive polymers possessing antibacterial and anti-hiv-1 activities

Sawada, Hideo, Kawai, Yoshikazu, Kawase, Tokuzo, Inaba Masashi Sugiya, Yoshiko, Sugiya, Masashi, Baba, Masanori, and Tomita, Toshio

International Journal of Polymeric Materials 2005. 54(4): 257-277

21. 47551 HIV-LS-325; WOS-HIV-6/19/2005

Discovery of natural product inhibitors of HIV-1 integrase at Merck

Singh, SB, Pelaez, F, Hazuda, DJ, and Lingham, RB

DRUGS OF THE FUTURE 2005. 30(3): 277-299, 23


22. 47552 HIV-LS-325; WOS-HIV-6/19/2005

New drug targets for HIV

Bean, P



23. 47553 HIV-LS-325; WOS-HIV-6/26/2005

New inhibitors of the Tat-TAR RNA interaction found with a "fuzzy" pharmacophore model

Renner, S, Ludwig, V, Boden, O, Scheffer, U, Gobel, M, and Schneider, G

CHEMBIOCHEM 2005. 6(6): 1119-1125, 7


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