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1. 47980 HIV-LS-333; PUBMED-HIV-10/17/2005

Improving the Antiviral Efficacy and Selectivity of HIV-1 Reverse Transcriptase Inhibitor TSAO-T by the Introduction of Functional Groups at the N-3 Position

Bonache, MC, Chamorro, C, Velazquez, S , De Clercq, E, Balzarini, J, Barrios, FR, Gago, F, Camarasa, MJ, and San-Felix, A

J Med Chem 2005. 48(21): 6653-6660


2. 47981 HIV-LS-333; PUBMED-HIV-10/17/2005

HIV-1. Viral assembly inhibitors on the horizon

Brazil, M

Nat Rev Drug Discov 2005. 4(9): 716-7


3. 47982 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Substituted benzodiazepines as inhibitors of the chemokine receptor CXCR4 and use in the inhibition of HIV infectivity

Marshall, Garland

PATENT: US 2005192272 ISSUE DATE: 20050901

APPLICATION: 2004-21345 PP: 15 pp.


4. 47983 HIV-LS-333; PUBMED-HIV-10/17/2005

Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues

Sun, GF, Kuang, YY, Chen, FE, De, Clercq E, Balzarini, J, and Pannecouque, C

Arch Pharm (Weinheim) 2005. 338(10): 457-461


5. 47984 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Antiviral activity and safety of 873140, a novel CCR5 antagonist, during short-term monotherapy in HIV-infected adults

Lalezari, Jacob, Thompson, Melanie, Kumar, Priny, Piliero, Peter, Davey, Richard, Patterson, Kristine, Shachoy-Clark, Anne, Adkison, Kimberly, Demarest, James, Lou, Yu, Berrey, Michelle, and Piscitelli, Stephen

AIDS (London, United Kingdom) 2005. 19(14): 1443-1448

6. 47985 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Preparation of naphthyridinecarboxamides as HIV integrase inhibitors

Johns, Brian Alvin, Boros, Eric Eugene, Kawasuji, Takashi, Koble, Cecilia S, Kurose, Noriyuki, Murai, Hitoshi, Sherrill, Ronald George, and Weatherhead, Jason Gordon

PATENT: WO 2005077050 ISSUE DATE: 20050825

APPLICATION: 2005 PP: 447 pp.

ASSIGNEE: (Smithkline Beecham Corporation, USA and Shionogi & Co., Ltd

7. 47986 HIV-LS-333; PUBMED-HIV-10/17/2005

Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains

Zhao, C, Sham, HL, Sun, M, Stoll, VS, Stewart, KD, Lin, S, Mo, H, Vasavanonda, S, Saldivar, A, Park, C, McDonald, EJ, Marsh, KC, Klein, LL, Kempf, DJ, and Norbeck, DW

Bioorg Med Chem Lett 2005.


8. 47987 HIV-LS-333; PUBMED-HIV-10/17/2005

2-(Aryl)-3-furan-2-ylmethyl-thiazolidin-4-ones as selective HIV-RT Inhibitors

Rawal, RK, Prabhakar, YS, Katti, SB, and De, Clercq E

Bioorg Med Chem 2005.


9. 47988 HIV-LS-333; PUBMED-HIV-10/17/2005

Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein

Haffar, O, Dubrovsky, L, Lowe, R, Berro, R, Kashanchi, F, Godden, J, Vanpouille, C, Bajorath, J, and Bukrinsky, M

J Virol 2005. 79(20): 13028-36


10. 47989 HIV-LS-333; SCIFINDER-HIV-10/11/2005

HIV gp41 HR2-derived synthetic peptides, and their use in anti-AIDS therapy to inhibit transmission of human immunodeficiency virus

Delmedico, Mary K and Dwyer, John

PATENT: WO 2005067960 ISSUE DATE: 20050728

APPLICATION: 2004 PP: 93 pp.

ASSIGNEE: (Trimeris, Inc. USA

11. 47990 HIV-LS-333; PUBMED-HIV-10/17/2005

Protease inhibitors and non-nucleoside reverse transcriptase inhibitors have a comparable effect on the CD4 cell change after switching to tenofovir-based regimens

van Leth, F, Prins, JM, Lange, JM, and Geerlings, SE

AIDS 2005. 19(15): 1722-1723


12. 47991 HIV-LS-333; PUBMED-HIV-10/17/2005

Safety and distribution of cellulose acetate 1,2-benzenedicarboxylate (CAP), a candidate anti-HIV microbicide in rhesus macaques

Ratterree, M, Gettie, A, Williams, V, Malenbaum, S, Neurath, AR, Cheng-Mayer, C, and Blanchard, J

AIDS 2005. 19 (15): 1595-1599


13. 47992 HIV-LS-333; WOS-HIV-10/09/2005

Design of a folding inhibitor of the HIV-1 protease

Tiana, G, Broglia, RA, Sutto, L, and Provasi, D

MOLECULAR SIMULATION 2005. 31(11): 765-771, 7


14. 47993 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Polypeptide multimers comprising coiled coil structure and a-helical structure for use as antiviral, anti-HIV and anti-SIV agents

Weiss, Carol D, He, Yong, Vassell, Russell, and De, Rosny Eve

PATENT: WO 2005018666 ISSUE DATE: 20050303

APPLICATION: 2003 PP: 84 pp.

ASSIGNEE: (The Government of the United States of America, as Represented by the Department of Health and Human Services USA and De Rosny, Eve

15. 47994 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Hiv integrase inhibitors

Williams, Peter D, Wai, John S, Embrey, Mark W, Staas, Donnette D, Zhuang, Linghang, and Langford, HMarie

PATENT: WO 2005092099 ISSUE DATE: 20051006

APPLICATION: 2005 PP: 135 pp.

ASSIGNEE: (Merck & Co., Inc. USA

16. 47995 HIV-LS-333; WOS-HIV-10/09/2005

A soluble factor secreted by an HIV-1-resistant cell line blocks transcription through inactivating the DNA-binding capacity of the NF-kappa B p65/p50 dimer

Lesner, A, Li, YC, Nitkiewicz, J, Li, GH, Kartvelishvili, A, Kartvelishvili, M, and Simm, M

JOURNAL OF IMMUNOLOGY 2005. 175(4): 2548-2554, 7


17. 47996 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Methods using a combination of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine and another anti-HIV agent for treating HIV infection

Lin, Pin-Fang, Nowicka-Sans, Beata, and Yamanaka, Gregory

PATENT: US 20050215545 ISSUE DATE: 20050929

APPLICATION: 2005-64683 PP: 14 pp.


18. 47997 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Methods using a combination of 1-benzoyl-4-[2-[4-fluoro-7-(1H-1,2,3-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]piperazine and another anti-HIV agent for treating HIV infection

Lin, Pin-Fang, Nowicka-Sans, Beata, and Yamanaka, Gregory

PATENT: US 20050215544 ISSUE DATE: 20050929

APPLICATION: 2005-61273 PP: 14 pp.


19. 47998 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Methods using a combination of 1-benzoyl-4-[2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-1,2-dioxoethyl]-piperazine and another anti-HIV agent for treating HIV infection

Lin, Pin-Fang, Nowicka-Sans, Beata, and Yamanaka, Gregory

PATENT: US 20050215543 ISSUE DATE: 20050929

APPLICATION: 2005-57667 PP: 14 pp.


20. 47999 HIV-LS-333; SCIFINDER-HIV-10/11/2005

Hiv integrase inhibitors

Han, Wei, Egbertson, Melissa, Wai, John S, Zhuang, Linghang, Ruzek, Rowena D, Perlow, Debra S, and Obligado, Vanessa E

PATENT: WO 2005087767 ISSUE DATE: 20050922

APPLICATION: 2005 PP: 83 pp.

ASSIGNEE: (Merck & Co., Inc. USA

21. 48000 HIV-LS-333; SCIFINDER-HIV-10/11/2005

5-Hydroxyindole-3-carboxylates derivatives and their application as anti-HBV or anti-HIV agents

Gong, Ping and Zhao, Yanfang

PATENT: WO 2005087729 ISSUE DATE: 20050922

APPLICATION: 2005 PP: 68 pp.

ASSIGNEE: (Shenyang Pharmaceutical University, Peop. Rep. China

22. 48001 HIV-LS-333; WOS-HIV-10/09/2005

Development and application of a high-throughput screening assay for HIV-1 integrase enzyme activities

John, S, Fletcher, TM, and Jonsson, CB



23. 48002 HIV-LS-333; WOS-HIV-10/09/2005

A novel homodimeric lactose-binding lectin from the edible split gill medicinal mushroom Schizophyllum commune

Han, CH, Liu, QH, Ng, TB, and Wang, HX



24. 48003 HIV-LS-333; WOS-HIV-10/09/2005

Antiviral activity of SPD754 against clinical isolates of HIV-1 resistant to other nucleoside reverse transcriptase inhibitors

Bethell, RC, Parkin, N, and Lie, Y

ANTIVIRAL THERAPY 2003. 8(3): U21-U22, 2


25. 48004 HIV-LS-333; WOS-HIV-10/09/2005

Molecular mechanisms of resistance to tenofovir by HIV-1 reverse transcriptase containing a di-serine insertion after residue 69 and multiple thymidine analogue-associated mutations

White, KL, Chen, JM, Margot, NA, Wrin, T, Petropoulos, CJ, Naeger, LK, Swaminathan, S, and Miller, MD

ANTIVIRAL THERAPY 2003. 8(3): U44-U45, 2


26. 48005 HIV-LS-333; WOS-HIV-10/09/2005

Rare 1 and 2 amino acid insertions in the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket of HIV-1 reverse transcriptase affect NNRTI susceptibility

Winters, MA, Kagan, RM, Heseltine, PNR, Kovari, L, and Merigan, TC

ANTIVIRAL THERAPY 2003. 8(3): U52-U53, 2


27. 48006 HIV-LS-333; WOS-HIV-10/09/2005

The impact of the HIV reverse transcriptase M184V mutation in combination with single thymidine analogue mutations on nucleoside reverse transcriptase inhibitor resistance in clinical samples from a large patient database

Ross, L, Parkin, N, Bates, M, Fisher, R, St, Clair M, Tisdale, M, and Lanier, R

ANTIVIRAL THERAPY 2003. 8(3): U134-U135, 2


28. 48007 HIV-LS-333; WOS-HIV-10/16/2005

HIV-1 Nef regulates the release of superoxide anions from human macrophages

Olivetta, E, Pietraforte, D, Schiavoni, I, Minetti, M, Federico, M, and Sanchez, M

BIOCHEMICAL JOURNAL 2005. 390: 591-602, 12


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