ONLINE DATABASE SEARCH - HIV-LS-333-MEMO
1. 47980 HIV-LS-333; PUBMED-HIV-10/17/2005
Improving the Antiviral Efficacy and Selectivity of HIV-1 Reverse Transcriptase Inhibitor TSAO-T by the Introduction of Functional Groups at the N-3 Position
Bonache, MC, Chamorro, C, Velazquez, S , De Clercq, E, Balzarini, J, Barrios, FR, Gago, F, Camarasa, MJ, and San-Felix, A
J Med Chem 2005. 48(21): 6653-6660
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16220981&dopt=abstract
2. 47981 HIV-LS-333; PUBMED-HIV-10/17/2005
HIV-1. Viral assembly inhibitors on the horizon
Brazil, M
Nat Rev Drug Discov 2005. 4(9): 716-7
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16211702&dopt=abstract
3. 47982 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Substituted benzodiazepines as inhibitors of the chemokine receptor CXCR4 and use in the inhibition of HIV infectivity
Marshall, Garland
PATENT: US 2005192272 ISSUE DATE: 20050901
APPLICATION: 2004-21345 PP: 15 pp.
ASSIGNEE: (USA)
4. 47983 HIV-LS-333; PUBMED-HIV-10/17/2005
Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues
Sun, GF, Kuang, YY, Chen, FE, De, Clercq E, Balzarini, J, and Pannecouque, C
Arch Pharm (Weinheim) 2005. 338(10): 457-461
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16211654&dopt=abstract
5. 47984 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Antiviral activity and safety of 873140, a novel CCR5 antagonist, during short-term monotherapy in HIV-infected adults
Lalezari, Jacob, Thompson, Melanie, Kumar, Priny, Piliero, Peter, Davey, Richard, Patterson, Kristine, Shachoy-Clark, Anne, Adkison, Kimberly, Demarest, James, Lou, Yu, Berrey, Michelle, and Piscitelli, Stephen
AIDS (London, United Kingdom) 2005. 19(14): 1443-1448
6. 47985 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Preparation of naphthyridinecarboxamides as HIV integrase inhibitors
Johns, Brian Alvin, Boros, Eric Eugene, Kawasuji, Takashi, Koble, Cecilia S, Kurose, Noriyuki, Murai, Hitoshi, Sherrill, Ronald George, and Weatherhead, Jason Gordon
PATENT: WO 2005077050 ISSUE DATE: 20050825
APPLICATION: 2005 PP: 447 pp.
ASSIGNEE: (Smithkline Beecham Corporation, USA and Shionogi & Co., Ltd
7. 47986 HIV-LS-333; PUBMED-HIV-10/17/2005
Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains
Zhao, C, Sham, HL, Sun, M, Stoll, VS, Stewart, KD, Lin, S, Mo, H, Vasavanonda, S, Saldivar, A, Park, C, McDonald, EJ, Marsh, KC, Klein, LL, Kempf, DJ, and Norbeck, DW
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16203141&dopt=abstract
8. 47987 HIV-LS-333; PUBMED-HIV-10/17/2005
2-(Aryl)-3-furan-2-ylmethyl-thiazolidin-4-ones as selective HIV-RT Inhibitors
Rawal, RK, Prabhakar, YS, Katti, SB, and De, Clercq E
Bioorg Med Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16198576&dopt=abstract
9. 47988 HIV-LS-333; PUBMED-HIV-10/17/2005
Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein
Haffar, O, Dubrovsky, L, Lowe, R, Berro, R, Kashanchi, F, Godden, J, Vanpouille, C, Bajorath, J, and Bukrinsky, M
J Virol 2005. 79(20): 13028-36
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16189005&dopt=abstract
10. 47989 HIV-LS-333; SCIFINDER-HIV-10/11/2005
HIV gp41 HR2-derived synthetic peptides, and their use in anti-AIDS therapy to inhibit transmission of human immunodeficiency virus
Delmedico, Mary K and Dwyer, John
PATENT: WO 2005067960 ISSUE DATE: 20050728
APPLICATION: 2004 PP: 93 pp.
ASSIGNEE: (Trimeris, Inc. USA
11. 47990 HIV-LS-333; PUBMED-HIV-10/17/2005
Protease inhibitors and non-nucleoside reverse transcriptase inhibitors have a comparable effect on the CD4 cell change after switching to tenofovir-based regimens
van Leth, F, Prins, JM, Lange, JM, and Geerlings, SE
AIDS 2005. 19(15): 1722-1723
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16184059&dopt=abstract
12. 47991 HIV-LS-333; PUBMED-HIV-10/17/2005
Safety and distribution of cellulose acetate 1,2-benzenedicarboxylate (CAP), a candidate anti-HIV microbicide in rhesus macaques
Ratterree, M, Gettie, A, Williams, V, Malenbaum, S, Neurath, AR, Cheng-Mayer, C, and Blanchard, J
AIDS 2005. 19 (15): 1595-1599
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16184028&dopt=abstract
13. 47992 HIV-LS-333; WOS-HIV-10/09/2005
Design of a folding inhibitor of the HIV-1 protease
Tiana, G, Broglia, RA, Sutto, L, and Provasi, D
MOLECULAR SIMULATION 2005. 31(11): 765-771, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232032600004
14. 47993 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Polypeptide multimers comprising coiled coil structure and a-helical structure for use as antiviral, anti-HIV and anti-SIV agents
Weiss, Carol D, He, Yong, Vassell, Russell, and De, Rosny Eve
PATENT: WO 2005018666 ISSUE DATE: 20050303
APPLICATION: 2003 PP: 84 pp.
ASSIGNEE: (The Government of the United States of America, as Represented by the Department of Health and Human Services USA and De Rosny, Eve
15. 47994 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Hiv integrase inhibitors
Williams, Peter D, Wai, John S, Embrey, Mark W, Staas, Donnette D, Zhuang, Linghang, and Langford, HMarie
PATENT: WO 2005092099 ISSUE DATE: 20051006
APPLICATION: 2005 PP: 135 pp.
ASSIGNEE: (Merck & Co., Inc. USA
16. 47995 HIV-LS-333; WOS-HIV-10/09/2005
A soluble factor secreted by an HIV-1-resistant cell line blocks transcription through inactivating the DNA-binding capacity of the NF-kappa B p65/p50 dimer
Lesner, A, Li, YC, Nitkiewicz, J, Li, GH, Kartvelishvili, A, Kartvelishvili, M, and Simm, M
JOURNAL OF IMMUNOLOGY 2005. 175(4): 2548-2554, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232010400065
17. 47996 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Methods using a combination of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine and another anti-HIV agent for treating HIV infection
Lin, Pin-Fang, Nowicka-Sans, Beata, and Yamanaka, Gregory
PATENT: US 20050215545 ISSUE DATE: 20050929
APPLICATION: 2005-64683 PP: 14 pp.
ASSIGNEE: (USA)
18. 47997 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Methods using a combination of 1-benzoyl-4-[2-[4-fluoro-7-(1H-1,2,3-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]piperazine and another anti-HIV agent for treating HIV infection
Lin, Pin-Fang, Nowicka-Sans, Beata, and Yamanaka, Gregory
PATENT: US 20050215544 ISSUE DATE: 20050929
APPLICATION: 2005-61273 PP: 14 pp.
ASSIGNEE: (USA)
19. 47998 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Methods using a combination of 1-benzoyl-4-[2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-1,2-dioxoethyl]-piperazine and another anti-HIV agent for treating HIV infection
Lin, Pin-Fang, Nowicka-Sans, Beata, and Yamanaka, Gregory
PATENT: US 20050215543 ISSUE DATE: 20050929
APPLICATION: 2005-57667 PP: 14 pp.
ASSIGNEE: (USA)
20. 47999 HIV-LS-333; SCIFINDER-HIV-10/11/2005
Hiv integrase inhibitors
Han, Wei, Egbertson, Melissa, Wai, John S, Zhuang, Linghang, Ruzek, Rowena D, Perlow, Debra S, and Obligado, Vanessa E
PATENT: WO 2005087767 ISSUE DATE: 20050922
APPLICATION: 2005 PP: 83 pp.
ASSIGNEE: (Merck & Co., Inc. USA
21. 48000 HIV-LS-333; SCIFINDER-HIV-10/11/2005
5-Hydroxyindole-3-carboxylates derivatives and their application as anti-HBV or anti-HIV agents
Gong, Ping and Zhao, Yanfang
PATENT: WO 2005087729 ISSUE DATE: 20050922
APPLICATION: 2005 PP: 68 pp.
ASSIGNEE: (Shenyang Pharmaceutical University, Peop. Rep. China
22. 48001 HIV-LS-333; WOS-HIV-10/09/2005
Development and application of a high-throughput screening assay for HIV-1 integrase enzyme activities
John, S, Fletcher, TM, and Jonsson, CB
JOURNAL OF BIOMOLECULAR SCREENING 2005. 10(6): 606-614, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231985900008
23. 48002 HIV-LS-333; WOS-HIV-10/09/2005
A novel homodimeric lactose-binding lectin from the edible split gill medicinal mushroom Schizophyllum commune
Han, CH, Liu, QH, Ng, TB, and Wang, HX
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2005. 336(1): 252-257, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231941500037
24. 48003 HIV-LS-333; WOS-HIV-10/09/2005
Antiviral activity of SPD754 against clinical isolates of HIV-1 resistant to other nucleoside reverse transcriptase inhibitors
Bethell, RC, Parkin, N, and Lie, Y
ANTIVIRAL THERAPY 2003. 8(3): U21-U22, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231265900015
25. 48004 HIV-LS-333; WOS-HIV-10/09/2005
Molecular mechanisms of resistance to tenofovir by HIV-1 reverse transcriptase containing a di-serine insertion after residue 69 and multiple thymidine analogue-associated mutations
White, KL, Chen, JM, Margot, NA, Wrin, T, Petropoulos, CJ, Naeger, LK, Swaminathan, S, and Miller, MD
ANTIVIRAL THERAPY 2003. 8(3): U44-U45, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231265900045
26. 48005 HIV-LS-333; WOS-HIV-10/09/2005
Rare 1 and 2 amino acid insertions in the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket of HIV-1 reverse transcriptase affect NNRTI susceptibility
Winters, MA, Kagan, RM, Heseltine, PNR, Kovari, L, and Merigan, TC
ANTIVIRAL THERAPY 2003. 8(3): U52-U53, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231265900056
27. 48006 HIV-LS-333; WOS-HIV-10/09/2005
The impact of the HIV reverse transcriptase M184V mutation in combination with single thymidine analogue mutations on nucleoside reverse transcriptase inhibitor resistance in clinical samples from a large patient database
Ross, L, Parkin, N, Bates, M, Fisher, R, St, Clair M, Tisdale, M, and Lanier, R
ANTIVIRAL THERAPY 2003. 8(3): U134-U135, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231265900153
28. 48007 HIV-LS-333; WOS-HIV-10/16/2005
HIV-1 Nef regulates the release of superoxide anions from human macrophages
Olivetta, E, Pietraforte, D, Schiavoni, I, Minetti, M, Federico, M, and Sanchez, M
BIOCHEMICAL JOURNAL 2005. 390: 591-602, 12
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232069900022