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1. 61304 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Topochemical models for anti-HIV activity of 1-alkoxy-5-alkyl-6-(arylthio)uracils

Bajaj, S and Madan, AK

Chem. Pap. 2007. 61(2): 127-132

2. 61305 HIV-LS-379; SCIFINDER-HIV-7/16/2007

N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a rationally designed non-nucleoside reverse transcriptase inhibitor compound with potent anti-HIV activity

Uckun, Fatih M, Qazi, Sanjive, and Venkatachalam, Taracad

Arzneim. Forsch. 2007. 57(5): 278-285

3. 61306 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Synergistic inhibition of protease-inhibitor-resistant HIV type 1 by saquinavir in combination with atazanavir or lopinavir

Dam, Elisabeth, Lebel-Binay, Sophie, Rochas, Severine, Thibaut, Laurent, Faudon, Jean-Louis, Thomas, Claire-Marie, Essioux, Laurent, Hill, Andrew, Schutz, Malte, and Clavel, Francois

Antiviral Ther. 2007. 12(3): 371-380

4. 61307 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Maribavir: 1263W94, benzimidavir, GW 1263, GW 1263W94, VP41263


Drugs R&D 2007. 8(3): 188-192

5. 61308 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Human immunodeficiency virus type 1 variants resistant to first- and second-version fusion inhibitors and cytopathic in ex vivo human lymphoid tissue

Chinnadurai, Raghavan, Rajan, Devi, Muench, Jan, and Kirchhoff, Frank

J. Virol. 2007. 81(12): 6563-6572

6. 61309 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Preparation of pyrimidine derivatives as HIV integrase inhibitors

Naidu, Narasimhulu B, Ueda, Yasutsugu, and Connolly, Timothy P

PATENT: WO 2007064619 ISSUE DATE: 20070607

APPLICATION: 2006 PP: 129pp.

ASSIGNEE: (Bristol-Myers Squibb Company, USA

7. 61310 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Anti-viral griffithsin proteins and methods of inhibiting viral infections

O'Keefe, Barry R, Mori, Toshiyuki, and McMahon, James B

PATENT: WO 2007064844 ISSUE DATE: 20070607

APPLICATION: 2006 PP: 79pp.

ASSIGNEE: (Government of the United States of America, Represented by the Secretary Department of Health and Human Services USA

8. 61311 HIV-LS-379; WOS-HIV-7/13/2007

Synthesis of Novel Pett Analogues: 3,4-Dimethoxy Phenyl Ethyl 1,3,5-Triazinyl Thiourea Derivatives and Their Antibacterial and Anti-Hiv Studies

Patel, R. et al.

Journal of the Brazilian Chemical Society 2007. 18(2): 312-321


9. 61312 HIV-LS-379; WOS-HIV-7/13/2007

C34, a Membrane Fusion Inhibitor, Blocks Hiv Infection of Langerhans Cells and Viral Transmission to T Cells

Sugaya, M. et al.

Journal of Investigative Dermatology 2007. 127(6): 1436-1443


10. 61313 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Preparation of acyclic nucleotides as antiviral agents

Zhao, Mingyan and Zhong, Suling

PATENT: CN 1966514 ISSUE DATE: 20070523

APPLICATION: 1011-7768 PP: 15pp.

ASSIGNEE: (Beijing Meibeita Pharmaceutical Co., Ltd. Peop. Rep. China

11. 61314 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Synthesis and in vitro antiviral studies of bis (pivaloyloxymethyl) ester derivative of 9-{((phosphonomethyl) aziridin-1-yl)methyl}adenine (PMAMA) and analogues

Sheikha, Ghassan MAbu, Bkhaitan, Majdi M, Al-Hourani, Rami A, Qaisi, Ali M, Loddo, Roberta, and La Colla, Paolo

Saudi Pharm. J. 2007. 15(1): 16-22

12. 61315 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Inhibition of HIV-1 multiplication by a modified U7 snRNA inducing Tat and Rev exon skipping

Asparuhova, Maria B, Marti, Gabriela, Liu, Songkai, Serhan, Fatima, Trono, Didier, and Schumperli, Daniel

J. Gene Med. 2007. 9(5): 323-334

13. 61316 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Pharmaceutical combination of nucleoside and nucleotide reverse transcriptase inhibitors

Lulla, Amar and Malhotra, Geena

PATENT: WO 2007068934 ISSUE DATE: 20070621

APPLICATION: 2006 PP: 25pp.

ASSIGNEE: (Cipla Limited, India and Curtis, Philip Anthony

14. 61317 HIV-LS-379; WOS-HIV-7/13/2007

Preclinical Safety Assessments of Uc781 Anti-Human Immunodeficiency Virus Topical Microbicide Formulations

Patton, D. et al.

Antimicrobial Agents and Chemotherapy 2007. 51(5): 1608-1615


15. 61318 HIV-LS-379; WOS-HIV-7/13/2007

Preclinical Testing of Candidate Topical Microbicides for Anti-Human Immunodeficiency Virus Type 1 Activity and Tissue Toxicity in a Human Cervical Explant Culture

Cummins, J. et al.

Antimicrobial Agents and Chemotherapy 2007. 51(5): 1770-1779


16. 61319 HIV-LS-379; SCIFINDER-HIV-7/16/2007

HIV gp41 C-terminal Heptad Repeat Contains Multifunctional Domains: relation to mechanisms of action of anti-HIV peptides

Liu, Shuwen, Jing, Weiguo, Cheung, Byron, Lu, Hong, Sun, Jane, Yan, Xuxia, Niu, Jinkui, Farmar, James, Wu, Shuguang, and Jiang, Shibo

J. Biol. Chem. 2007. 282(13): 9612-9620

17. 61320 HIV-LS-379; SCIFINDER-HIV-7/16/2007

Glucuronidation of anti-HIV drug candidate bevirimat: identification of human UDP-glucuronosyltransferases and species differences

Wen, Zhiming, Martin, David E, Bullock, Peter, Lee, Kuo-Hsiung, and Smith, Philip C

Drug Metab. Dispos. 2007. 35(3): 440-448

18. 61321 HIV-LS-379; WOS-HIV-7/20/2007

Enfuvirtide: the First Step for a New Strategy of Antiretroviral Therapy.

Bottaro, E.

Medicina-Buenos Aires 2007. 67(2): 195-205


19. 61322 HIV-LS-379; WOS-HIV-7/20/2007

Nucleoside Reverse Transcriptase Inhibitors and Human Immunodeficiency Virus Proteins Cause Axonal Injury in Human Dorsal Root Ganglia Cultures

Robinson, B., Li, Z., and Nath, A.

Journal of Neurovirology 2007. 13(2): 160-167


20. 61323 HIV-LS-379; WOS-HIV-7/20/2007

A Dimeric Lactone From Ardisia Japonica With Inhibitory Activity for Hiv-1 and Hiv-2 Ribonuclease H

Dat, N. et al.

Journal of Natural Products 2007. 70(5): 839-841


21. 61324 HIV-LS-379; WOS-HIV-7/20/2007

Development of a Novel Fusion Inhibitor Against T-20-Resistant Hiv-1

Qishi, S. et al.

Biopolymers 2007. 88(4): 524


22. 61325 HIV-LS-379; WOS-HIV-7/20/2007

Synthesis of Biotinyl-Tn-14403, Anti-Hiv Peptide Amide

Nedev, H. and Saragovi, H.

Biopolymers 2007. 88(4): 583


23. 61326 HIV-LS-379; WOS-HIV-7/20/2007

Anti-Hiv Dendrimeric Peptides

Yu, Q. et al.

Biopolymers 2007. 88(4): 603


24. 61327 HIV-LS-379; WOS-HIV-7/20/2007

Testing Antiretroviral Drug Efficacy in Conventional Mice Infected With Chimeric Hiv-1

Hadas, E. et al.

Aids 2007. 21 (8): 905-909


25. 61328 HIV-LS-379; WOS-HIV-7/20/2007

High-Throughput Real-Time Assay Based on Molecular Beacons for Hiv-1 Integrase 3 '-Processing Reaction

He, H. et al.

Acta Pharmacologica Sinica 2007. 28(6): 811-817


26. 61329 HIV-LS-379; PUBMED-HIV-7/23/2007

Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus

Dwyer, JJ, Wilson, KL, Davison, DK, Freel, SA, Seedorff, JE, Wring, SA, Tvermoes, NA, Matthews, TJ, Greenberg, ML, and Delmedico, MK

Proc Natl Acad Sci U S A 2007.


27. 61330 HIV-LS-379; PUBMED-HIV-7/23/2007

In Vitro Antiviral Activity and Cross-Resistance Profile of PL-100, a Next Generation Protease Inhibitor of Human Immunodeficiency Virus Type 1

Dandache, S, Sevigny, G, Yelle, J, Stranix, BR, Parkin, N, Schapiro, JM, Wainberg, MA, and Wu, JJ

Antimicrob Agents Chemother 2007.


28. 61331 HIV-LS-379; PUBMED-HIV-7/23/2007

N(2)-Benzyloxycarbonylguan-9-yl Acetic Acid Derivatives as HIV-1 Reverse Transcriptase Non-Nucleoside Inhibitors with Decreased Loss of Potency Against Common Drug-Resistance Mutations

Adebambo, KF, Zanoli, S, Thomas, MG, Cancio, R, Howarth, NM, and Maga, G

ChemMedChem 2007.


29. 61332 HIV-LS-379; PUBMED-HIV-7/23/2007

Protein-protein interactions as new targets for drug design: virtual and experimental approaches

Ivanov, AS, Gnedenko, OV, Molnar, AA, Mezentsev, YV, Lisitsa, AV, and Archakov, AI

J Bioinform Comput Biol 2007. 5(2b): 579-92


30. 61333 HIV-LS-379; PUBMED-HIV-7/23/2007

Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization

Koh, Y, Matsumi, S, Das, D, Amano, M, Davis, DA, Li, J, Leschenko, S, Baldridge, A, Shioda, T, Yarchoan, R, Ghosh, AK, and Mitsuya, H

J Biol Chem 2007.


31. 61334 HIV-LS-379; PUBMED-HIV-7/23/2007

Iron chelators ICL670 and 311 inhibit HIV-1 transcription

Debebe, Z, Ammosova, T, Jerebtsova, M, Kurantsin-Mills, J, Niu, X, Charles, S, Richardson, DR, Ray, PE, Gordeuk, VR, and Nekhai, S

Virology 2007.


32. 61335 HIV-LS-379; PUBMED-HIV-7/23/2007

Ketoconazole is inferior to ritonavir as an alternative booster for saquinavir in a once daily regimen in Thai HIV-1 infected patients

Autar, RS, Wit, FW, Sankote, J, Sutthichom, D, Kimenai, E, Hassink, E, Hill, A, Cooper, DA, Phanuphak, P, Lange, JM, Burger, DM, and Ruxrungtham, K

AIDS 2007. 21 (12): 1535-1539


33. 61336 HIV-LS-379; PUBMED-HIV-7/23/2007

New developments in diketo-containing inhibitors of HIV-1 integrase

Zhao, G, Wang, C, Liu, C, and Lou, H

Mini Rev Med Chem 2007. 7(7): 707-25


34. 61337 HIV-LS-379; PUBMED-HIV-7/23/2007

Synthesis and biological evaluation of 2,3-diaryl substituted-1,3-thiazolidin-4-ones as anti-HIV agents

Rawal, RK, Tripathi, RK, Katti, SB, Pannecouque, C, and De, Clercq E

Med Chem 2007. 3(4): 355-63


35. 61338 HIV-LS-379; PUBMED-HIV-7/23/2007

An Update in the Development of HIV Entry Inhibitors

Rusconi, S, Scozzafava, A, Mastrolorenzo, A, and Supuran, CT

Curr Top Med Chem 2007. 7(13): 1273-89


36. 61339 HIV-LS-379; PUBMED-HIV-7/23/2007

Bis and tris indole alkaloids from marine organisms: new leads for drug discovery

Gupta, L, Talwar, A, and Chauhan, PM

Curr Med Chem 2007. 14(16): 1789-803


37. 61340 HIV-LS-379; PUBMED-HIV-7/23/2007

HIV Integrase Inhibitors: From Diketoacids to Heterocyclic Templates: A History of HIV Integrase Medicinal Chemistry at Merck West Point and Merck Rome (IRBM)

Egbertson, MS

Curr Top Med Chem 2007. 7(13): 1251-72


38. 61341 HIV-LS-379; PUBMED-HIV-7/23/2007

HIV-1 Integrase: From Biology to Chemotherapeutics

Zeinalipour-Loizidou, E, Nicolaou, C, Nicolaides, A, and Kostrikis, LG

Curr HIV Res 2007. 5(4): 365-88


39. 61342 HIV-LS-379; PUBMED-HIV-7/23/2007

In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection

Terrazas-Aranda, K, Van Herrewege, Y, Lewi, PJ, Van Roey, J, and Vanham, G

Antivir Chem Chemother 2007. 18(3): 141-151


40. 61343 HIV-LS-379; PUBMED-HIV-7/23/2007

A Versatile Route to C-6 Arylmethyl-Functionalized S-DABO and Related Analogues

Radi, M, Contemori, L, Castagnolo, D, Spinosa, R, Este, JA, Massa, S, and Botta, M

Org Lett 2007.


41. 61344 HIV-LS-379; PUBMED-HIV-7/23/2007

Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex

Biglione, S, Byers, SA, Price, JP, Nguyen, VT, Bensaude, O, Price, DH, and Maury, W

Retrovirology 2007. 4(1): 47


42. 61345 HIV-LS-379; PUBMED-HIV-7/23/2007

Anti-Vpr Activities of Heat Shock Protein 27

Liang, D, Benko, Z, Agbottah, E, Bukrinsky, M, and Zhao, RY

Mol Med 2007.


43. 61346 HIV-LS-379; PUBMED-HIV-7/23/2007

In vitro Suppression of K65R Reverse Transcriptase-mediated Tenofovir- and Adefovir-5' Diphosphate Resistance Conferred by the Borano-phosphonate Derivatives

Frangeul, A, Barral, K, Alvarez, K, and Canard, B

Antimicrob Agents Chemother 2007.


44. 61347 HIV-LS-379; PUBMED-HIV-7/23/2007

Evaluation of the In Vitro Antiviral Activity of the Novel, Tyrosyl-based Human Immunodeficiency Virus Type 1 Protease Inhibitor Brecanavir (BCV, GW640385, 385) in Combination with Other Antiretrovirals and Against a Panel of Protease Inhibitor-Resistant HIV

Hazen, R, Harvey, R, Ferris, R, Craig, C, Yates, P, Griffin, P, Miller, J, Kaldor, I, Ray, J, Samano, V, Furfine, E, Spaltenstein, A, Hale, M, Tung, R, St, Clair M, Hanlon, M, and Boone, L

Antimicrob Agents Chemother 2007.


45. 61348 HIV-LS-379; PUBMED-HIV-7/23/2007

Bioinformatic approaches for modeling the substrate specificity of HIV-1 protease: an overview

Rognvaldsson, T, You, L, and Garwicz, D

Expert Rev Mol Diagn 2007. 7(4): 435-51


46. 61349 HIV-LS-379; PUBMED-HIV-7/23/2007

HIV entry inhibitors

Este, JA and Telenti, A

Lancet 2007. 370(9581): 81-8


47. 61350 HIV-LS-379; PUBMED-HIV-7/23/2007

Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and Integrase

Wang, Z, Bennett, EM, Wilson, DJ, Salomon, C, and Vince, R

J Med Chem 2007. 50(15): 3416-9


48. 61351 HIV-LS-379; PUBMED-HIV-7/23/2007

Benzyl amide-ketoacid inhibitors of HIV-integrase

Walker, MA, Johnson, T, Naidu, BN, Banville, J, Remillard, R, Plamondon, S, Martel, A, Li, C, Torri, A, Samanta, H, Lin, Z, Dicker, I, Krystal, M, and Meanwell, NA

Bioorg Med Chem Lett 2007.


49. 61352 HIV-LS-379; PUBMED-HIV-7/23/2007

Diels-Alder Approach for the Construction of Halogenated, o-Nitro Biaryl Templates and Application to the Total Synthesis of the Anti-HIV Agent Siamenol

Naffziger, MR, Ashburn, BO, Perkins, JR, and Carter, RG

J Org Chem 2007.


50. 61353 HIV-LS-379; PUBMED-HIV-7/23/2007

Suppression of HIV replication using RNA interference against HIV-1 integrase

Lau, TS, Li, Y, Kameoka, M, Ng, TB, and Wan, DC

FEBS Lett 2007. 581(17): 3253-9


51. 61354 HIV-LS-379; PUBMED-HIV-7/23/2007

Pharmacokinetics and antiretroviral response to darunavir/ritonavir and etravirine combination in patients with high-level viral resistance

Boffito, M, Winston, A, Jackson, A, Fletcher, C, Pozniak, A, Nelson, M, Moyle, G, Tolowinska, I, Hoetelmans, R, Miralles, D, and Gazzard, B

AIDS 2007. 21 (11): 1449-1455


52. 61355 HIV-LS-379; PUBMED-HIV-7/23/2007

HIV-1 Protease: Structure, Dynamics, and Inhibition

Louis, JM, Ishima, R, Torchia, DA, and Weber, IT

Adv Pharmacol 2007. 55: 261-98


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