1. Dual-targeted anti-TB/anti-HIV Heterodimers. Alexandrova, L., S. Zicari, E. Matyugina, A. Khandazhinskaya, T. Smirnova, S. Andreevskaya, L. Chernousova, C. Vanpouille, S. Kochetkov, and L. Margolis. Antiviral Research, 2017. 145: p. 175-183. PMID[28743447]. PMCID[PMC5576140].
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2. GRL-09510, a Unique P2-crown-retrahydrofuranylurethane-containing HIV-1 Protease Inhibitor, Maintains its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in Vitro. Amano, M., P. Miguel Salcedo-Gomez, R.S. Yedidi, N.S. Delino, H. Nakata, K. Venkateswara Rao, A.K. Ghosh, and H. Mitsuya. Scientific Reports, 2017. 7(12235): 12pp. PMID[28947797].
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3. Synthesis of Some Substituted 5H-Furo[3,2-g]chromene and Benzofuran sulfonate Derivatives as Potent anti-HIV Agents. Amr, A.E., M.M. Abdalla, S.A. Essaouy, M.M.H. Areef, M.H. Elgamal, T.A. Nassear, A.E. Haschich, and M.A. Al-Omar. Russian Journal of General Chemistry, 2017. 87(7): p. 1591-1600. ISI[000408427200024].
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4. Design and Synthesis of Potent HIV-1 Protease Inhibitors with (S)-Tetrahydrofuran-tertiary Amine-acetamide as P2-ligand: Structure-activity Studies and Biological Evaluation. Bai, X., Z. Yang, M. Zhu, B. Dong, L. Zhou, G. Zhang, J. Wang, and Y. Wang. European Journal of Medicinal Chemistry, 2017. 137: p. 30-44. PMID[28554091].
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5. Potent in vivo NK Cell-mediated Elimination of HIV-1-infected Cells Mobilized by a gp120-bispecific and Hexavalent Broadly Neutralizing Fusion Protein. Bardhi, A., Y. Wu, W. Chen, W. Li, Z. Zhu, J.H. Zheng, H. Wong, E. Jeng, J. Jones, C. Ochsenbauer, J.C. Kappes, D.S. Dimitrov, T. Ying, and H. Goldstein. Journal of Virology, 2017. 91(20): e00937-17. PMID[28794022].
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6. Natural Killer (NK) Cell Receptor-HLA Ligand Genotype Combinations Associated with Protection from HIV Infection: Investigation of How Protective Genotypes Influence Anti HIV NK Cell Functions. Bernard, N.F. AIDS Research and Therapy, 2017. 14(1): p. 38. PMID[28893287]. PMCID[PMC5594513].
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7. Effects of Amprenavir on HIV-1 Maturation, Production and Infectivity Following Drug Withdrawal in Chronically-infected Monocytes/macrophages. Borrajo, A., A. Ranazzi, M. Pollicita, R. Bruno, A. Modesti, C. Alteri, C.F. Perno, V. Svicher, and S. Aquaro. Viruses, 2017. 9(10): e277. PMID[28956865].
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8. Covalent Inhibitors for Eradication of Drug-resistant HIV-1 Reverse Transcriptase: From Design to Protein Crystallography. Chan, A.H., W.G. Lee, K.A. Spasov, J.A. Cisneros, S.N. Kudalkar, Z.O. Petrova, A.B. Buckingham, K.S. Anderson, and W.L. Jorgensen. Proceedings of the National Academy of Sciences of the United States of America, 2017. 114(36): p. 9725-9730. PMID[28827354]. PMCID[PMC5594698].
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9. Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae. Chen, H., R. Zhang, R.H. Luo, L.M. Yang, R.R. Wang, X.J. Hao, and Y.T. Zheng. Molecules, 2017. 22(9): e1498. PMID[28885587].
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10. Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-resistant Variants of Human Immunodeficiency Virus Type 1, and its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131. Cihlar, T., A.S. Ray, C.G. Boojamra, L. Zhang, H. Hui, G. Laflamme, J.E. Vela, D. Grant, J. Chen, F. Myrick, K.L. White, Y. Gao, K.Y. Lin, J.L. Douglas, N.T. Parkin, A. Carey, R. Pakdaman, and R.L. Mackman. Antimicrobial Agents and Chemotherapy, 2008. 52(2): p. 655-665. PMID[18056282]. PMCID[PMC2224772].
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11. HIV-1 Infection Inhibition by Neem (Azadirachta indica A. Juss.) Leaf Extracts and Azadirachtin. David, P.E., S.G.L. Benjamin, E. Delia, N.H.M. Patricia, and C.V.M.M. del. Indian Journal of Traditional Knowledge, 2017. 16(3): p. 437-441. ISI[000407987700011].
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12. N-Hydroxy-substituted 2-Aryl acetamide Analogs: A Novel Class of HIV-1 Integrase Inhibitors. Debnath, U., P. Kumar, A. Agarwal, A. Kesharwani, S.K. Gupta, and S.B. Katti. Chemical Biology & Drug Design, 2017. 90(4): p. 527-534. PMID[28294572].
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13. Virtual Screening of Acyclovir Derivatives as Potential Antiviral Agents: Design, Synthesis, and Biological Evaluation of New Acyclic Nucleoside Protides. Derudas, M., C. Vanpouille, D. Carta, S. Zicari, G. Andrei, R. Snoeck, A. Brancale, L. Margolis, J. Balzarini, and C. McGuigan. Journal of Medicinal Chemistry, 2017. 60(18): p. 7876-7896. PMID[28829913].
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14. Efficacy of Carbosilane dendrimers with an Antiretroviral Combination against HIV-1 in the Presence of Semen-derived Enhancer of Viral Infection. Garcia-Broncano, P., R. Cena-Diez, F.J. de la Mata, R. Gomez, S. Resino, and M.A. Munoz-Fernandez. European Journal of Pharmacology, 2017. 811: p. 155-163. PMID[28577966].
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15. Development of Pyridine Dicoumarols as Potent Anti HIV-1 Leads, Targeting HIV-1 Associated TopoisomeraseIIβ Kinase. Kammari, K., K. Devaraya, A. Bommakanti, and A.K. Kondapi. Future Medicinal Chemistry, 2017. 9(14): p. 1597-1609. PMID[28891315].
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16. A 2-Hydroxyisoquinoline-1,3-dione Active-site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase. Kirby, K.A., N.A. Myshakina, M.T. Christen, Y.L. Chen, H.A. Schmidt, A.D. Huber, Z. Xi, S. Kim, R.K. Rao, S.T. Kramer, Q. Yang, K. Singh, M.A. Parniak, Z. Wang, R. Ishima, and S.G. Sarafianos. Antimicrobial Agents and Chemotherapy, 2017. 61(10): e01351-17. PMID[28760905]. PMCID[PMC5610509].
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17. Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue. Lee, W.A., G.X. He, E. Eisenberg, T. Cihlar, S. Swaminathan, A. Mulato, and K.C. Cundy. Antimicrobial Agents and Chemotherapy, 2005. 49(5): p. 1898-1906. PMID[15855512]. PMCID[PMC1087627].
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18. One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-infected Cells. Li, W., Y.L. Wu, D.S. Kong, H.J. Yang, Y.P. Wang, J.P. Shao, Y. Feng, W.Z. Chen, L.Y. Ma, T.L. Ying, and D.S. Dimitrov. Scientific Reports, 2017. 7(9130): 12pp. PMID[28831040]. PMCID[PMC5567353].
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19. The Effect of Bovine BST2A1 on the Release and Cell-to-Cell Transmission of Retroviruses. Liang, Z., Y. Zhang, J. Song, H. Zhang, S. Zhang, Y. Li, J. Tan, and W. Qiao. Virology Journal, 2017. 14(1): p. 173. PMID[28877726]. PMCID[PMC5588738].
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20. Efficacy Analysis of Combinatorial siRNAs against HIV Derived from One Double Hairpin RNA Precursor. Liu, C., Z.P. Liang, and X.H. Kong. Frontiers in Microbiology, 2017. 8: p. 1651. PMID[28900421]. PMCID[PMC5581867].
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21. Development of anti-HIV Peptides Based on a Viral Capsid Protein. Mizuguchi, T., N. Ohashi, D. Matsumoto, C. Hashimoto, W. Nomura, N. Yamamoto, T. Murakami, and H. Tamamura. Biopolymers, 2017. 108(1): e22920. PMID[27428649].
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22. Design, Synthesis and Biological Evaluation of Indole Derivatives as Vif Inhibitors. Pu, C.L., R.H. Luo, M.Q. Zhang, X.Y. Hou, G.Y. Yan, J. Luo, Y.T. Zheng, and R. Li. Bioorganic & Medicinal Chemistry Letters, 2017. 27(17): p. 4150-4155. PMID[28754362].
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23. Synthesis and Evaluation of Isoflavones as Potential Anti-inflammatory Inhibitors. Ramaite, I.D.I., M.D. Maluleke, and S.S. Mnyakeni-Moleele. Arabian Journal for Science and Engineering, 2017. 42(10): p. 4263-4271. ISI[000408695500005].
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24. N-terminally Truncated POM121C Inhibits HIV-1 Replication. Saito, H., H. Takeuchi, T. Masuda, T. Noda, and S. Yamaoka. Plos One, 2017. 12(9): p. e0182434. PMID[28873410]. PMCID[PMC5584925].
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25. Natural Seminal Amyloids as Targets for Development of Synthetic Inhibitors of HIV Transmission. Sheik, D.A., S. Dewhurst, and J. Yang. Accounts of Chemical Research, 2017. 50(9): p. 2159-2166. PMID[28809479].
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26. Antiretroviral Activity of the Conjugates 3'-Azido-3'deoxythymidine and Derivatives of 1,3-Diacylglycerides. Siniavin, A., S. Grinkina, Y. Zhernov, N. Shastina, and M. Khaitov. Allergy, 2017. 72: p. 164. ISI[000408773101033].
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27. Vorinostat Renders the Replication-competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells. Sung, J.A., K. Sholtis, J. Kirchherr, J.D. Kuruc, C.L. Gay, J.L. Nordstrom, C.M. Bollard, N.M. Archin, and D.M. Margolis. EBioMedicine, 2017. 23: p. 52-58. PMID[28803740]. PMCID[PMC5605299].
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28. A Clue to Unprecedented Strategy to HIV Eradication: "Lock-in and Apoptosis."Tateishi, H., K. Monde, K. Anraku, R. Koga, Y. Hayashi, H.I. Ciftci, H. DeMirci, T. Higashi, K. Motoyama, H. Arima, M. Otsuka, and M. Fujita. Scientific Reports, 2017. 7(8957): 8pp. PMID[28827668]. PMCID[PMC5567282].
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29. Discovery of a Novel HIV-1 Integrase/P75 Interacting Inhibitor by Docking Screening, Biochemical Assay, and in Vitro Studies. Wang, Y., H.Q. Lin, P. Wang, J.S. Hu, T.M. Ip, L.M. Yang, Y.T. Zheng, and D. Chi-Cheong Wan. Journal of Chemical Information and Modeling, 2017. 57(9): p. 2336-2343. PMID[28837332].
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30. A Chalcone Derivative Reactivates Latent HIV-1 Transcription through Activating P-TEFb and Promoting Tat-SEC Interaction on Viral Promoter. Wu, J., M.T. Ao, R. Shao, H.R. Wang, D. Yu, M.J. Fang, X. Gao, Z. Wu, Q. Zhou, and Y.H. Xue. Scientific Reports, 2017. 7(10657): 12pp. PMID[28878233]. PMCID[PMC5587564].
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31. Small-molecule Screening Using a Human Primary Cell Model of HIV Latency Identifies Compounds that Reverse Latency without Cellular Activation. Yang, H.C., S. Xing, L. Shan, K. O'Connell, J. Dinoso, A. Shen, Y. Zhou, C.K. Shrum, Y. Han, J.O. Liu, H. Zhang, J.B. Margolick, and R.F. Siliciano. The Journal of Clinical Investigation, 2009. 119(11): p. 3473-3486. PMID[19805909]. PMCID[PMC2769176].
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33. Structure-guided Optimization of HIV Integrase Strand Transfer Inhibitors. Zhao, X.Z., S.J. Smith, D.P. Maskell, M. Metifiot, V.E. Pye, K. Fesen, C. Marchand, Y. Pommier, P. Cherepanov, S.H. Hughes, and T.R. Burke, Jr. Journal of Medicinal Chemistry, 2017. 60(17): p. 7315-7332. PMID[28737946]. PMCID[PMC5601359].
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