1. Inhibition of HIV-1 RT Activity by a New Series of 3-(1,3,4-Thiadiazol-2-yl)thiazolidin-4-one Derivatives. Buemi, M.R., R. Gitto, L. Ielo, C. Pannecouque, and L. De Luca. Bioorganic & Medicinal Chemistry, 2020. 28(8): 115431. PMID[32197813].
[PubMed]. HIV_03_2020.
2. 3D-QSAR, Molecular Docking, and Molecular Dynamics Simulation of a Novel Thieno[3,4-d]pyrimidine Inhibitor Targeting Human Immunodeficiency Virus Type 1 Reverse Transcriptase. Chu, H., Q.X. He, J.W. Wang, Y.T. Deng, J. Wang, Y. Hu, Y.Q. Wang, and Z.H. Lin. Journal of Biomolecular Structure & Dynamics. 2019: 12pp. PMID[31760877].
[PubMed]. HIV_03_2020.
3. 2-(Arylamino)-6-(trifluoromethyl)nicotinic acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication. Corona, A., V. Onnis, C. Del Vecchio, F. Esposito, Y.C. Cheng, and E. Tramontano. Molecules, 2020. 25(6): E1338. PMID[32183488].
[PubMed]. HIV_03_2020.
4. 1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-associated Ribonuclease H Activity. Desantis, J., S. Massari, A. Corona, A. Astolfi, S. Sabatini, G. Manfroni, D. Palazzotti, V. Cecchetti, C. Pannecouque, E. Tramontano, and O. Tabarrini. Molecules, 2020. 25(5): E1183. PMID[32151066].
[PubMed]. HIV_03_2020.
5. Synthesis and Molecular Docking of Novel N-((2-Chloroquinolin-3-yl)methylene)-4-methylbenzenamine Derivatives as anti-HIV-1 Reverse Transcriptase Inhibitors. Fazlinezhad, M., A. Nakhaei, H. Eshghi, and M. Saadatmandzadeh. Eurasian Chemical Communication, 2019. 1(2): p. 125-133. ISI[000498905700001].
[WOS]. HIV_03_2020.
6. Molecular Docking, Design, Synthesis and Biological Evaluation of Novel 2,3-Aryl-thiazolidin-4-ones as Potent NNRTIs. Geronikaki, A., A. Petrou, V. Kartsev, P. Eleftheriou, R. Boga, B. Bartolo, E. Crespan, G. Franco, and G. Maga. SAR and QSAR in Environmental Research. 30(10):697-714. PMID[31542957].
[PubMed]. HIV_03_2020.
7. Asymmetric Diels-Alder Reaction of 3-(Acyloxy)acryloyl oxazolidinones: Optically Active Synthesis of a High-affinity Ligand for Potent HIV-1 Protease Inhibitors. Ghosh, A.K., A. Grillo, S. Kovela, and M. Brindisi. RSC Advances, 2019. 9(71): p. 41755-41763. ISI[000503782700038].
[WOS]. HIV_03_2020.
8. Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-ligand X-Ray Structural Studies. Ghosh, A.K., Z.L. Xia, S. Kovela, W.L. Robinson, M.E. Johnson, D.W. Kneller, Y.F. Wang, M. Aoki, Y. Takamatsu, I.T. Weber, and H. Mitsuya. ChemMedChem. PMID[31439492].
[PubMed]. HIV_03_2020.
9. Fimepinostat, a Novel Dual Inhibitor of HDAC and PI3K, Effectively Reverses HIV-1 Latency ex Vivo without T Cell Activation. Gunst, J.D., K. Kjaer, R. Olesen, T.A. Rasmussen, L. Ostergaard, P.W. Denton, O.S. Sogaard, and M. Tolstrup. Journal of Virus Eradication, 2019. 5(3): p. 133-137. PMID[31700656].
[PubMed]. HIV_03_2020.
10. Design, Synthesis, Docking Studies and Biological Activities Novel 2,3-Diaryl-4-quinazolinone Derivatives as anti-HIV-1 Agents. Hajimandi, Z., R. Zabihollahi, M.R. Aghasadeghi, and A. Zarghi. Current HIV Research, 2019. 17(3): p. 214-222. PMID[31518225].
[PubMed]. HIV_03_2020.
11. Synthesis, Biological Evaluation and in Silico Modeling of Novel Integrase Strand Transfer Inhibitors (INSTIs). Ivashchenko, A.A., Y.A. Ivanenkov, A.G. Koryakova, R.N. Karapetian, O.D. Mitkin, V.A. Aladinskiy, D.V. Kravchenko, N.P. Savchuk, and A.V. Ivashchenko. European Journal of Medicinal Chemistry, 2020. 189: 112064. PMID[31972393].
[PubMed]. HIV_03_2020.
12. Synthesis of 4'-Substituted-2'-deoxy-2'-alpha-fluoro Nucleoside Analogs as Potential Antiviral Agents.Kasthuri, M., C. Li, K. Verma, O.O. Russell, L. Dickson, L. McCormick, L. Bassit, F. Amblard, and R.F. Schinazi. Molecules, 2020. 25(6): E1258. PMID[32168734].
[PubMed]. HIV_03_2020.
13. In Vitro anti-HIV-1 Activity of Ethyl gallate. Krishna, C.M., J.N. Kolla, S. Asha, and T.S.K. Reddy. VirusDisease, 2020. 31(1): p. 22-27. PMID[32206695]. PMCID[PMC7085494].
[PubMed]. HIV_03_2020.
14. Stability Behaviour of Antiretroviral Drugs and Their Combinations. 11: Characterization of Interaction Products of Zidovudine and Efavirenz, and Evaluation of Their Anti HIV-1 Activity, and Physiochemical and ADMET Properties. Kurmi, M., A. Sahu, A. Balhara, I.P. Singh, S. Kulkarni, N.K. Singh, P. Garg, and S. Singh. Journal of Pharmaceutical and Biomedical Analysis, 2020. 178: 112911. PMID[31627078].
[PubMed]. HIV_03_2020.
15. Click Chemistry-based Two-component System for Efficient Inhibition of Human Immunodeficiency Virus (HIV) Reverse Transcriptase (RT). Ledezma, C.E., E.M. Cornett, and D.M. Kolpashchikov. ACS Omega, 2020. 5(8): p. 4167-4171. PMID[32149246]. PMCID[PMC7057708].
[PubMed]. HIV_03_2020.
16. Scaffold Hopping in Discovery of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors: From CH(CN)-Dabos to CH(CN)-DAPYs. Li, T.T., C. Pannecouque, E. De Clercq, C.L. Zhuang, and F.E. Chen. Molecules, 2020. 25(7): E1581. PMID[32235557].
[PubMed]. HIV_03_2020.
17. Prenylated Coumarins from the Fruits of Manilkara zapota with Potential anti-Inflammatory Effects and anti-HIV Activities. Liu, Y.P., G. Yan, J.M. Guo, Y.Y. Liu, Y.J. Li, Y.Y. Zhao, L. Qiang, and Y.H. Fu. Journal of Agricultural and Food Chemistry, 2019. 67(43): p. 11942-11947. PMID[31622090].
[PubMed]. HIV_03_2020.
18. Synthesis and Biological Evaluation of bis-N(2),N(2)'-(4-Hydroxycoumarin-3-yl)ethylidene]-2,3-dihydroxysuccinodihydrazides. Manyeruke, M.H., T. Tshiwawa, H.C. Hoppe, M. Isaacs, R. Seldon, D.F. Warner, R.W.M. Krause, and P.T. Kaye. Bioorganic & Medicinal Chemistry Letters, 2020. 30(5): 126911. PMID[31952962].
[PubMed]. HIV_03_2020.
19. Antiviral Activity of Tenofovir alafenamide against HIV-1 with Thymidine Analog-associated Mutations and M184V.Margot, N., R. Ram, M. Abram, R. Haubrich, and C. Callebaut. Antimicrobial Agents and Chemotherapy, 2020. 64(4). PMID[31988104].
[PubMed]. HIV_03_2020.
20. Daphneodorins A-C, anti-HIV Gnidimacrin Related Macrocyclic Daphnane orthoesters from Daphne odora. Otsuki, K., W. Li, Y. Asada, C.H. Chen, K.H. Lee, and K. Koike. Organic Letters, 2020. 22(1): p. 11-15. PMID[31680527].
[PubMed]. HIV_03_2020.
21. In Vitro anti-HIV Activity of Some Indian Medicinal Plant Extracts. Palshetkar, A., N. Pathare, N. Jadhav, M. Pawar, A. Wadhwani, S. Kulkarni, and K.K. Singh. BMC Complementary Medicine and Therapies, 2020. 20(69): 11pp. PMID[32143607]. PMCID[PMC7076815].
[PubMed]. HIV_03_2020.
22. Pharmacophore-fusing Design of Pyrimidine sulfonylacetanilides as Potent Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase. Sang, Y., C. Pannecouque, E. De Clercq, C. Zhuang, and F. Chen. Bioorganic Chemistry, 2020. 96: 103595. PMID[32006797].
[PubMed]. HIV_03_2020.
23. Conformational Restriction Design of Thiophene-biphenyl-DAPY HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors.Sang, Y.L., S. Han, C. Pannecouque, E. De Clercq, C.L. Zhuang, and F.E. Chen. European Journal of Medicinal Chemistry, 2019. 182: 111603. PMID[31421633].
[PubMed]. HIV_03_2020.
24. Synthesis, anti-HIV-1 and Antiproliferative Evaluation of Novel 4-Nitroimidazole Derivatives Combined with 5-Hydroxy-4-pyridinone Moiety. Shirvani, P., A. Fassihi, L. Saghaie, S. Van Belle, Z. Debyser, and F. Christ. Journal of Molecular Structure, 2020. 1202: 127344. ISI[000501486700100].
[WOS]. HIV_03_2020.
25. Design, Synthesis and Structure-Activity Relationships of 4-Phenyl-1H-1,2,3-triazole Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Promising Antiviral Activities. Sun, L., T. Huang, A. Dick, M.E. Meuser, W.A. Zalloum, C.H. Chen, X. Ding, P. Gao, S. Cocklin, K.H. Lee, P. Zhan, and X. Liu. European Journal of Medicinal Chemistry, 2020. 190: 112085. PMID[32066010]. PMCID[PMC7053825].
[PubMed]. HIV_03_2020.
26. Synthesis and Biological Evaluation of a Series of 2-(((5-Akly/Aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones as Potential HIV-1 Inhibitors. Wu, Y., C. Tang, R. Rui, L. Yang, W. Ding, J. Wang, Y. Li, C.C. Lai, Y. Wang, R. Luo, W. Xiao, H. Zhang, Y. Zheng, and Y. He. Acta Pharmaceutica Sinica B, 2020. 10(3): p. 512-528. PMID[32140396]. PMCID[PMC7049619].
[PubMed]. HIV_03_2020.
27. Discovery, Synthesis, and Optimization of an N-Alkoxy Indolylacetamide against HIV-1 Carrying NNRTI-resistant Mutations from the Isatis indigotica Root. Xu, C., Y. Xin, M. Chen, M. Ba, Q. Guo, C. Zhu, Y. Guo, and J. Shi. European Journal of Medicinal Chemistry, 2020. 189: 112071. PMID[32004936]. PMCID[PMC7111291].
[PubMed]. HIV_03_2020.
28. Dual Effects of the Novel Ingenol Derivatives on the Acute and Latent HIV-1 Infections. Yang, H., X. Li, X.Y. Yang, P.P. Lu, Y.A. Wang, Z.T. Jiang, H.Y. Pan, L. Zhao, Y.Q. Zhu, I.U. Khan, Y.Z. Shen, H.Z. Lu, T. Zhang, G.C. Jiang, Z.J. Ma, H. Wu, and H.Z. Zhu. Antiviral Research, 2019. 169: 104555. PMID[31295520].
[PubMed]. HIV_03_2020.
29. Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors. Yu, D., Y. Su, X. Ding, Y. Zhu, B. Qin, H. Chong, S. Cui, and Y. He. Viruses, 2020. 12(3): E326. PMID[32197300].
[PubMed]. HIV_03_2020.
30. Design, Synthesis, and Biological Evaluation of 2-Amino-N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide Derivatives as Potent HIV-1 Vif Inhibitors. Zhang, R.H., S. Wang, R.H. Luo, M. Zhou, H. Zhang, G.B. Xu, Y.L. Zhao, Y.J. Li, Y.L. Wang, G.Y. Yan, S.G. Liao, Y.T. Zheng, and R. Li. Bioorganic & Medicinal Chemistry Letters, 2019. 29(24): 126638. PMID[31685340].
[PubMed]. HIV_03_2020.
31. Discovery of Novel Indolylarylsulfones as Potent HIV-1 NNRTIs via Structure-guided Scaffold Morphing.Zhao, T., Q. Meng, D.W. Kang, J.B. Ji, E. De Clercq, C. Pannecouque, X.Y. Liu, and P. Zhan. European Journal of Medicinal Chemistry, 2019. 182: 111619. PMID[31434039].
[PubMed]. HIV_03_2020.
Patent Citations
32. Preparation of Substituted Arylethylacetamides Human Immunodeficiency Virus Replication Inhibitors. Iwuagwu, C., K.E. Parcella, and K.M. Peese. Patent. 2020. 2019-IB57710 2020053811: 111pp.
[Patent]. HIV_03_2020.
33. Preparation of Nucleoside Fatty acid Carbonates Useful in HIV Therapy. Miller, J., D. Temelkoff, E.J. Velthuisen, M.A. De la Rosa, and L.S. Suwandi. Patent. 2020. 2019-IB57242 2020044257: 73pp.
[Patent]. HIV_03_2020.