1. The Combination of Venetoclax and Ixazomib Selectively and Efficiently Kills HIV-infected Cell Lines but Has Unacceptable Toxicity in Primary Cell Models. Alto, A., S. Natesampillai, A.P. Chandrasekar, A. Krogman, A. Misra, F. Shweta, C. VanLith, J.D. Yao, N.W. Cummins, and A.D. Badley. Journal of Virology, 2021. 95(12): e00138-21. PMID[33827940].
[PubMed]. HIV_05_2021.
2. Infection with a Newly Designed Dual Fluorescent Reporter HIV-1 Effectively Identifies Latently Infected CD4(+) T Cells. Cai, J., H. Gao, J. Zhao, S. Hu, X. Liang, Y. Yang, Z. Dai, Z. Hong, and K. Deng. eLife, 2021. 10: e63810. PMID[33835029]. PMCID[PMC8041464].
[PubMed]. HIV_05_2021.
3. Anti-HIV-1 Reverse Transcriptase Property of Some Edible Mushrooms in Asia. Choengpanya, K., S. Ratanabunyong, S. Seetaha, L. Tabtimmai, and K. Choowongkomon. Saudi Journal of Biological Sciences, 2021. 28(5): p. 2807-2815. PMID[34012322]. PMCID[PMC8116966].
[PubMed]. HIV_05_2021.
4. Hydrophobic Pocket Occupation Design of Difluoro-biphenyl-diarylpyrimidines as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: From N-Alkylation to Methyl Hopping on the Pyrimidine Ring. Ding, L., C. Pannecouque, E. De Clercq, C. Zhuang, and F.E. Chen. Journal of Medicinal Chemistry, 2021. 64(8): p. 5067-5081. PMID[33851529].
[PubMed]. HIV_05_2021.
5. High-resolution View of HIV-1 Reverse Transcriptase Initiation Complexes and Inhibition by NNRTI Drugs. Ha, B., K.P. Larsen, J. Zhang, Z. Fu, E. Montabana, L.N. Jackson, D.H. Chen, and E.V. Puglisi. Nature Communications, 2021. 12(1): 2500. PMID[33947853]. PMCID[PMC8096811].
[PubMed]. HIV_05_2021.
6. Anti-HIV Activity of Cucurbitacin-D against Cigarette Smoke Condensate-induced HIV Replication in the U1 Macrophages. Kodidela, S., N. Sinha, A. Kumar, and S. Kumar. Viruses, 2021. 13(6): 1004. PMID[34072078].
[PubMed]. HIV_05_2021.
7. Structure-based Linker Optimization of 6-(2-Cyclohexyl-1-alkyl)-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones as Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Li, D.X., C.S. Zhang, W. Ding, S.M. Huang, L. Yu, N. Lu, W.K. Pan, Y.M. Li, E. De Clercq, C. Pannecouque, H.B. Zhang, Y.P. Wang, Y.P. He, and F.E. Chen. Chinese Chemical Letters, 2021. 32(3): p. 1020-1024. ISI[000642405100004].
[WOS]. HIV_05_2021.
8. Exploring the Anti-HIV-1 Reverse Transcriptase, Anti-inflammatory, Anti-Cancer Activities and Cytotoxicity of Two Fermented Commercial Herbal Concoctions Sold in Limpopo Province of South Africa. Ntlhamu, M.I., A.R. Ndhlala, and P. Masoko. BMC Complementary Medicine and Therapies, 2021. 21(1): 151. PMID[34039320]. PMCID[PMC8157459].
[PubMed]. HIV_05_2021.
9. Saponins: Extraction, Bio-medicinal Properties and Way Forward to Anti-viral Representatives. Sharma, P., A. Tyagi, P. Bhansali, S. Pareek, V. Singh, A. Ilyas, R. Mishra, and N.K. Poddar. Food and Chemical Toxicology, 2021. 150: 112075. PMID[33617964].
[PubMed]. HIV_05_2021.
10. Phorbol esters from the Latex of Euphorbia umbellata: Bioguided Isolation of Highly Potent HIV-1 Latency Interrupters in Virus Reservoir Cells. Tostes, J.B.F., A.L.D. Carvalho, A.J. Ribeiro da Silva, P.J.P. Mourão, D. Rossi Á, A. Tanuri, and A.C. Siani. Journal of Natural Products, 2021. 84(5): p. 1666-1670. PMID[33909429].
[PubMed]. HIV_05_2021.
11. Discovery of Ethyl Ketone-based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity. Yu, W., J. Liu, D. Clausen, Y. Yu, J.L. Duffy, M. Wang, S. Xu, L. Deng, T. Suzuki, C.C. Chung, R.W. Myers, D.J. Klein, J.I. Fells, M.K. Holloway, J. Wu, G. Wu, B.J. Howell, R.J.O. Barnard, and J. Kozlowski. Journal of Medicinal Chemistry, 2021. 64(8): p. 4709-4729. PMID[33797924].
[PubMed]. HIV_05_2021.
12. Active Components from Cassia abbreviata Prevent HIV-1 Entry by Distinct Mechanisms of Action. Zheng, Y., X.W. Yang, D. Schols, M. Mori, B. Botta, A. Chevigné, M. Mulinge, A. Steinmetz, J.C. Schmit, and C. Seguin-Devaux. International Journal of Molecular Sciences, 2021. 22(9): 5052. PMID[34068829]. PMCID[PMC8126241].
[PubMed]. HIV_05_2021.
Patent Citations
This month, no relevant HIV patents were identified.