1. In Vitro Antiviral Activity of Mentha cordifolia Plant Extract in HIV-1 Latently Infected Cells Using an Established Human Cell Line. de Paz-Silava, S.L.M., A.F.B. Victoriano-Belvis, N.G. Gloriani, Y. Hibi, K. Asamitsu, and T. Okamoto. AIDS Research and Human Retroviruses, 2022. 38(1): p. 64-72. PMID[34030452].
[PubMed]. HIV_01_2022.
2. GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile. Dicker, I., J.L. Jeffrey, T. Protack, Z. Lin, M. Cockett, Y. Chen, S.Y. Sit, M. Gartland, N.A. Meanwell, A. Regueiro-Ren, D. Drexler, J. Cantone, B. McAuliffe, and M. Krystal. Antimicrobial Agents and Chemotherapy, 2022. 66(1): e0187621. PMID[34780263]. PMCID[PMC8765437].
[PubMed]. HIV_01_2022.
3. Inhibitors of HIV-1 Nef-mediated Activation of the Myeloid Src-family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation. Emert-Sedlak, L.A., O. Moukha-Chafiq, H. Shi, S. Du, J.J. Alvarado, V. Pathak, S.G. Tanner, R.N. Hunter, M. Nebane, L. Chen, T.V. Ilina, R. Ishima, S. Zhang, Y.V. Kuzmichev, E.R. Wonderlich, S.M. Schader, C.E. Augelli-Szafran, R.G. Ptak, and T.E. Smithgall. ACS Infectious Diseases, 2022. 8(1): p. 91-105. PMID[34985256].
[PubMed]. HIV_01_2022.
4. Synthesis and in Vitro Study of Antiviral Activity of Glycyrrhizin Nicotinate Derivatives against HIV-1 Pseudoviruses and SARS-CoV-2 Viruses. Fomenko, V.V., N.B. Rudometova, O.I. Yarovaya, A.D. Rogachev, A.A. Fando, A.V. Zaykovskaya, N.I. Komarova, D.N. Shcherbakov, O.V. Pyankov, A.G. Pokrovsky, L.I. Karpenko, R.A. Maksyutov, and N.F. Salakhutdinov. Molecules, 2022. 27(1): 295. PMID[35011529]. PMCID[PMC8746574].
[PubMed]. HIV_01_2022.
5. Anti-HIV Compounds from the Deep-sea-derived Fungus Chaetomium globosum. Hu, H.Q., Y.H. Li, Z.W. Fan, W.L. Yan, Z.H. He, T.H. Zhong, Y.B. Gai, and X.W. Yang. Chemistry and Biodiversity, 2022. 19(1): e202100804. PMID[34799976].
[PubMed]. HIV_01_2022.
6. Piroxicam Analogs: Design, Synthesis, Docking Study and Biological Evaluation as Promising anti-HIV-1 Agents. Imani, A., S. Soleymani, R. Vahabpour, Z. Hajimahdi, and A. Zarghi. Medicinal Chemistry, 2022. 18(2): p. 209-219. PMID[33550978].
[PubMed]. HIV_01_2022.
7. Synthesis and anti-HIV Activity of a New Isoxazole Containing Disubstituted 1,2,4-Oxadiazoles Analogs. Kumar Kushwaha, P., K. Saurabh Srivastava, N. Kumari, R. Kumar, D. Mitra, and A. Sharon. Bioorganic & Medicinal Chemistry, 2022. 56: 116612. PMID[35026631].
[PubMed]. HIV_01_2022.
8. Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. Makarasen, A., S. Patnin, P. Vijitphan, N. Reukngam, P. Khlaychan, M. Kuno, P. Intachote, B. Saimanee, S. Sengsai, and S. Techasakul. Molecules, 2022. 27(2): 461. PMID[35056776]. PMCID[PMC8781960].
[PubMed]. HIV_01_2022.
9. The Ingenol-based Protein Kinase C Agonist GSK445A Is a Potent Inducer of HIV and SIV RNA Transcription. Okoye, A.A., R. Fromentin, H. Takata, J.H. Brehm, Y. Fukazawa, B. Randall, M. Pardons, V. Tai, J. Tang, J. Smedley, M. Axthelm, J.D. Lifson, L.J. Picker, D. Favre, L. Trautmann, and N. Chomont. Plos Pathogens, 2022. 18(1): e1010245. PMID[35041707]. PMCID[PMC8797195].
[PubMed]. HIV_01_2022.
10. Potent Anti-viral Activity of a Trispecific HIV Neutralizing Antibody in SHIV-infected Monkeys. Pegu, A., L. Xu, M.E. DeMouth, G. Fabozzi, K. March, C.G. Almasri, M.D. Cully, K. Wang, E.S. Yang, J. Dias, C.M. Fennessey, J. Hataye, R.R. Wei, E. Rao, J.P. Casazza, W. Promsote, M. Asokan, K. McKee, S.D. Schmidt, X. Chen, C. Liu, W. Shi, H. Geng, K.E. Foulds, S.F. Kao, A. Noe, H. Li, G.M. Shaw, T. Zhou, C. Petrovas, J.P. Todd, B.F. Keele, J.D. Lifson, N.A. Doria-Rose, R.A. Koup, Z.Y. Yang, G.J. Nabel, and J.R. Mascola. Cell Reports, 2022. 38(1): 110199. PMID[34986348]. PMCID[PMC8767641].
[PubMed]. HIV_01_2022.
11. Biophysical Characterization of Novel DNA Aptamers against K103N/Y181C Double Mutant HIV-1 Reverse transcriptase. Ratanabunyong, S., S. Seetaha, S. Hannongbua, S. Yanaka, M. Yagi-Utsumi, K. Kato, A. Paemanee, and K. Choowongkomon. Molecules, 2022. 27(1): 285. PMID[35011517]. PMCID[PMC8746315].
[PubMed]. HIV_01_2022.
12. Exploratory Studies on Soluble Small Molecule CD4 Mimics as HIV Entry Inhibitors. Tsuji, K., T. Kobayakawa, K. Konno, A. Masuda, K. Takahashi, N. Ohashi, K. Yoshimura, T. Kuwata, S. Matsushita, S. Harada, and H. Tamamura. Bioorganic & Medicinal Chemistry, 2022. 56: 116616. PMID[35063895].
[PubMed]. HIV_01_2022.
13. Long-acting Capsid Inhibitor Protects Macaques from Repeat SHIV Challenges. Vidal, S.J., E. Bekerman, D. Hansen, B. Lu, K. Wang, J. Mwangi, W. Rowe, F. Campigotto, J. Zheng, D. Kato, A. Chandrashekar, J. Barrett, S. Patel, H. Wan, T. Anioke, N.B. Mercado, J.P. Nkolola, M.J. Ferguson, W.J. Rinaldi, C. Callebaut, W. Blair, T. Cihlar, R. Geleziunas, S.R. Yant, and D.H. Barouch. Nature, 2022. 601(7894): p. 612-616. PMID[34875675]. PMCID[PMC8753592].
[PubMed]. HIV_01_2022.
14. Neuropilin-1, a Myeloid Cell-specific Protein, Is an Inhibitor of HIV-1 Infectivity. Wang, S., L. Zhao, X. Zhang, J. Zhang, H. Shang, and G. Liang. Proceedings of the National Academy of Science of the United States of America, 2022. 119(2): e2114884119. PMID[34987100]. PMCID[PMC8764665].
[PubMed]. HIV_01_2022.
15. Design, Synthesis, and Mechanistic Investigations of Phenylalanine Derivatives Containing a Benzothiazole Moiety as HIV-1 Capsid Inhibitors with Improved Metabolic Stability. Xu, S., L. Sun, A. Dick, W.A. Zalloum, T. Huang, M.E. Meuser, X. Zhang, Y. Tao, S. Cherukupalli, D. Ding, X. Ding, S. Gao, X. Jiang, D. Kang, E. De Clercq, C. Pannecouque, S. Cocklin, X. Liu, and P. Zhan. European Journal of Medicinal Chemistry, 2022. 227: 113903. PMID[34653770].
[PubMed]. HIV_01_2022.
16. Efficient Treatment and Pre-exposure Prophylaxis in Rhesus macaques by an HIV Fusion-inhibitory Lipopeptide. Xue, J., H. Chong, Y. Zhu, J. Zhang, L. Tong, J. Lu, T. Chen, Z. Cong, Q. Wei, and Y. He. Cell, 2022. 185(1): p. 131-144.e118. PMID[34919814].
[PubMed]. HIV_01_2022.
17. New Insights into the Structure of Kappa/Beta-Carrageenan: A Novel Potential Inhibitor of HIV-1. Yermak, I., S. Anastyuk, A. Kravchenko, W. Helbert, V. Glazunov, A. Shulgin, P. Spirin, and V. Prassolov. International Journal of Molecular Sciences, 2021. 22(23): 12905. PMID[34884718]. PMCID[PMC8657973].
[PubMed]. HIV_01_2022.
Patent Citations
This month, no relevant HIV patents were identified.