ONLINE DATABASE SEARCH - OI-LS-316-MEMO
1. 44898 OI-LS-316; PUBMED-OI-2/23/2005
Crystal Structure of Lumazine Synthase from Mycobacterium tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,)
Morgunova, E, Meining, W, Illarionov, B, Haase, I, Jin, G, Bacher, A, Cushman, M, Fischer, M, and Ladenstein, R
Biochemistry 2005. 44(8): 2746-2758
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15723519&dopt=abstract
2. 44899 OI-LS-316; PUBMED-OI-2/23/2005
Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis
Sandy, J, Holton, S, Fullam, E, Sim, E, and Noble, M
Protein Sci 2005. 14(3): 775-782
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15722451&dopt=abstract
3. 44900 OI-LS-316; EMBASE-OI-2/23/2005
DAHP synthase from Mycobacterium tuberculosis H37Rv: cloning, expression, and purification of functional enzyme
Rizzi, Caroline, Frazzon, Jeverson, Ely, Fernanda, Weber, Patricia G, da Fonseca, Isabel O, Gallas, Michelle, Oliveira, Jaim S, Mendes, Maria A, de Souza, Bibiana M, and Palma, Mario S
Protein Expression and Purification 2005. 40(1): 23-30
HYPERLINK:
http://www.sciencedirect.com/science/article/B6WPJ-4F00RT8-1/2/d26e8c36daf69be29a6e9168e5c2f605
4. 44901 OI-LS-316; PUBMED-OI-2/23/2005
Study of anticandidal activity of carvacrol and eugenol in vitro and in vivo
Chami, N, Bennis, S, Chami, F, Aboussekhra, A, and Remmal, A
Oral Microbiol Immunol 2005. 20(2): 106-111
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15720571&dopt=abstract
5. 44902 OI-LS-316; PUBMED-OI-2/23/2005
Laboratory approaches to the diagnosis of hepatitis C virus infection
Jerome, KR and Gretch, DR
Minerva Gastroenterol Dietol 2004. 50(1): 9-20
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15719002&dopt=abstract
6. 44903 OI-LS-316; EMBASE-OI-2/23/2005
Synthesis of isonicotinic acid N'-arylidene-N-[2-oxo-2-(4-aryl-piperazin-1-yl)-ethyl]-hydrazides as antituberculosis agents
Sinha, Neelima, Jain, Sanjay, Tilekar, Ajay, Upadhayaya, Ram Shankar, Kishore, Nawal, Jana, Gour Hari, and Arora, Sudershan K
Bioorganic & Medicinal Chemistry Letters 2005. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF9-4FJ5XJ4-5/2/5b09c2496690cb2960a3f583fd875fd2
7. 44904 OI-LS-316; PUBMED-OI-2/23/2005
Novel [2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-d-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide) Derivatives with Anti-HIV-1 and Anti-Human-Cytomegalovirus Activity
de Castro, S, Lobaton, E, Perez-Perez, MJ, San-Felix, A, Cordeiro, A, Andrei, G, Snoeck, R, De Clercq, E, Balzarini, J, Camarasa, MJ, and Velazquez, S
J Med Chem 2005. 48(4): 1158-1168
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15715482&dopt=abstract
8. 44905 OI-LS-316; EMBASE-OI-2/23/2005
Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure
Yamazaki, Kazuo, Kaneko, Yasushi, Suwa, Kie, Ebara, Shinji, Nakazawa, Kyoko, and Yasuno, Kazuhiro
Bioorganic & Medicinal Chemistry 2005. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF8-4FH0D6M-2/2/af50e1883f94ddf2d2ca1cfe5ee2336e
9. 44906 OI-LS-316; PUBMED-OI-2/23/2005
Crystal Structure of a Substrate Complex of Mycobacterium tuberculosis beta-Ketoacyl-acyl Carrier Protein Synthase III (FabH) with Lauroyl-coenzyme A
Musayev, F, Sachdeva, S, Neel Scarsdale, J, Reynolds, KA, and Wright, HT
J Mol Biol 2005. 346(5): 1313-1321
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15713483&dopt=abstract
10. 44907 OI-LS-316; PUBMED-OI-2/23/2005
Interferon Regulatory Factor 3-Independent Double-Stranded RNA-Induced Inhibition of Hepatitis C Virus Replicons in Human Embryonic Kidney 293 Cells
Ali, S and Kukolj, G
J Virol 2005 . 79(5): 3174-3178
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15709037&dopt=abstract
11. 44908 OI-LS-316; EMBASE-OI-2/23/2005
Antibacterial and antifungal activity of pinosylvin, a constituent of pine
Lee, SK, Lee, HJ, Min, HY, Park, EJ, Lee, KM, Ahn, YH, Cho, YJ, and Pyee, JH
Fitoterapia 2005. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6VSC-4FG4V7X-3/2/0daca8f1ad64b0db160dda433f3d03d5
12. 44909 OI-LS-316; PUBMED-OI-2/23/2005
Establishment of a subgenomic replicon for bovine viral diarrhea virus in huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response
Horscroft, N, Bellows, D, Ansari, I, Lai, VC, Dempsey, S, Liang, D, Donis, R, Zhong, W, and Hong, Z
J Virol 2005 . 79(5): 2788-2796
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15708997&dopt=abstract
13. 44910 OI-LS-316; EMBASE-OI-2/23/2005
Synthesis and antimycobacterial activities of glycosylated amino alcohols and amines
Katiyar, D, Tiwari, VK, Tewari, N, Verma, SS, Sinha, S, Gaikwad, A, Srivastava, A, Chaturvedi, V, Srivastava, R, Srivastava, BS, and Tripathi, RP
European Journal of Medicinal Chemistry 2005. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6VKY-4FCRFPD-2/2/3467d5e1ce6cf68499fdf8a276931500
14. 44911 OI-LS-316; PUBMED-OI-2/23/2005
(1)H and (13)C NMR characterization of pyridinium-type isoniazid-NAD adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis
Broussy, S, Bernardes-Genisson, V, Coppel, Y, Quemard, A, Bernadou, J, and Meunier, B
Org Biomol Chem 2005. 3(4): 670-673
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15703806&dopt=abstract
15. 44912 OI-LS-316; PUBMED-OI-2/23/2005
The OtsAB pathway is essential for trehalose biosynthesis in mycobacterium tuberculosis
Murphy, HN, Stewart, GR, Mischenko, VV, Apt, AS, Harris, R, McAlister, MS, Driscoll, PC, Young, DB, and Robertson, BD
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15703182&dopt=abstract
16. 44913 OI-LS-316; PUBMED-OI-2/23/2005
A hybrid between the antifungal azole eberconazole and the alkaloid onychine
Dombeck, F and Bracher, F
Pharmazie 2005. 60(1): 5-7
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15700771&dopt=abstract
17. 44914 OI-LS-316; PUBMED-OI-2/23/2005
Identification of inhibitors for a virally encoded protein kinase by 2 different screening systems: in vitro kinase assay and in-cell activity assay
Mett, H, Holscher, K, Degen, H, Esdar, C, De Neumann, BF, Flicke, B, Freudenreich, T, Holzer, G, Schinzel, S, Stamminger, T, Stein-Gerlach, M, Marschall, M, and Herget, T
J Biomol Screen 2005. 10(1): 36-45
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15695342&dopt=abstract
18. 44915 OI-LS-316; EMBASE-OI-2/23/2005
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines
Pratt, John K, Donner, Pamela, McDaniel, Keith F, Maring, Clarence J, Kati, Warren M, Mo, Hongmei, Middleton, Tim, Liu, Yaya, Ng, Teresa, and Xie, Qinghua
Bioorganic & Medicinal Chemistry Letters 2005. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF9-4FJ5XJ4-7/2/f484d1c313f9acfc8b877c4811b2c86d
19. 44916 OI-LS-316; EMBASE-OI-2/23/2005
Design and synthesis of a potent macrocyclic 1,6-napthyridine anti-human cytomegalovirus (HCMV) inhibitors
Falardeau, Guy, Lachance, Hugo, St-Pierre, Annie, Yannopoulos, Constantin G, Drouin, Marc, Bedard, Jean, and Chan, Laval
Bioorganic & Medicinal Chemistry Letters 2005. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF9-4FFGJ50-7/2/9a87fc85f79b22dc244fb6e2c58702be
20. 44917 OI-LS-316; EMBASE-OI-2/23/2005
Effect of the anti-cytomegalovirus (CMV) drug maribavir (MB) on the activities of cytochrome p450 (CYP) 1A2, 2C9, 2C19, 2D6, 3A, N-ACETYLTRANSFERASE-2 (NAT-2), and xanthine oxidase (XO) as assessed by the cooperstown 5+1 drug cocktail
Ma, JD, Nafziger, AN, Villano, SA, Gaedigk, A, Victory, J, and Bertino, JS
Clinical Pharmacology & Therapeutics 2005. 77(2): P19
HYPERLINK:
http://www.sciencedirect.com/science/article/B6WCN-4FDMRBG-2K/2/2c19d48c06a4524cc168e7bcb15ed5ca
21. 44918 OI-LS-316; PUBMED-OI-2/23/2005
Mutations responsible for Mycobacterium tuberculosis isoniazid resistance in Italy
Rindi, L, Bianchi, L, Tortoli, E, Lari, N, Bonanni, D, and Garzelli, C
Int J Tuberc Lung Dis 2005. 9(1): 94-97
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15675557&dopt=abstract
22. 44919 OI-LS-316; PUBMED-OI-2/23/2005
Assays for glucosidase inhibitors with potential antiviral activities: secreted alkaline phosphatase as a surrogate marker
Norton, PA, Conyers, B, Gong, Q, Steel, LF, Block, TM, and Mehta, AS
J Virol Methods 2005. 124(1-2): 167-172
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15664065&dopt=abstract
23. 44920 OI-LS-316; WOS-OI-2/13/2005
Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide
Mossa, JS, El-Feraly, FS, and Muhammad, I
PHYTOTHERAPY RESEARCH 2004. 18(11): 934-937, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226394300014
24. 44921 OI-LS-316; WOS-OI-2/13/2005
Intranasal application of lentinan enhances bactericidal activity of rat alveolar macrophages against Mycobacterium tuberculosis
Markova, N, Michailova, L, Kussovski, V, Jourdanova, M, and Radoucheva, T
PHARMAZIE 2005. 60(1): 42-48, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226409400008
25. 44922 OI-LS-316; WOS-OI-2/13/2005
Induction of colony-stimulating factors by a 30-kDa secretory protein of Mycobacterium tuberculosis H37Rv
Kaur, S, Kaur, H, and Singh, PP
EUROPEAN CYTOKINE NETWORK 2004. 15(4): 327-338, 12
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226373400007
26. 44923 OI-LS-316; WOS-OI-2/13/2005
Fatty acid synthesis as a target for antimalarial drug discovery
Lu, JZQ, Lee, PJ, Waters, NC, and Prigge, ST
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 2005. 8(1): 15-26, 12
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226436400003
27. 44924 OI-LS-316; WOS-OI-2/13/2005
Streamlining drug discovery informatics: Accelerating the flow from gene to structure to pre-clinical candidate
Artis, DR
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004. 227: U679-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000223655602471
28. 44925 OI-LS-316; WOS-OI-2/20/2005
Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses
Lee, MY, Park, CB, Dordick, JS, and Clark, DS
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2005. 102(4): 983-987, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226617900007
29. 44926 OI-LS-316; WOS-OI-2/20/2005
Bioactive carbohydrates and recently discovered analogues chemotherapeutics
Wrodnigg, TM and Sprenger, FKF
MINI-REVIEWS IN MEDICINAL CHEMISTRY 2004. 4(4): 437-459, 23
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226486800010
30. 44927 OI-LS-316; WOS-OI-2/20/2005
The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase
Leyssen, P, Balzarini, J, De Clercq, E , and Neyts, J
JOURNAL OF VIROLOGY 2005. 79(3): 1943-1947, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226634300061
31. 44928 OI-LS-316; WOS-OI-2/20/2005
NF-kappa B activation can mediate inhibition of human cytomegalovirus replication
Eickhoff, JE and Cotten, M
JOURNAL OF GENERAL VIROLOGY 2005. 86: 285-295, 11
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226738500005
32. 44929 OI-LS-316; WOS-OI-2/20/2005
Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains
Saeij, JPJ, Boyle, JP, Grigg, ME, Arrizabalaga, G, and Boothroyd, JC
INFECTION AND IMMUNITY 2005. 73(2): 695-702, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226731700004
33. 44930 OI-LS-316; WOS-OI-2/20/2005
Practical synthesis of a potent hepatitis C virus RNA replication inhibitor
Xu, F, Waters, M, Bio, MM, Savary, K, Cowden, C, Yang, CH, Reamer, RA, Buck, E, Song, ZGJ, Williams, JM, Tschaen, DM, Volante, RP, Grabowski, EJJ, and Tillyer, R
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004. 228: U121-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000223713800588
34. 44931 OI-LS-316; WOS-OI-2/20/2005
Synthesis of a proposed inhibitor of human cytomegalovirus (HCMV) using a tandem chain extension-aldol reaction approach
Lin, WM, Theberge, CR, and Zercher, CK
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004. 228: U133-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000223713800661