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ONLINE DATABASE SEARCH - OI-LS-316-MEMO

1. 44898 OI-LS-316; PUBMED-OI-2/23/2005

Crystal Structure of Lumazine Synthase from Mycobacterium tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,)

Morgunova, E, Meining, W, Illarionov, B, Haase, I, Jin, G, Bacher, A, Cushman, M, Fischer, M, and Ladenstein, R

Biochemistry 2005. 44(8): 2746-2758


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15723519&dopt=abstract


2. 44899 OI-LS-316; PUBMED-OI-2/23/2005

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis

Sandy, J, Holton, S, Fullam, E, Sim, E, and Noble, M

Protein Sci 2005. 14(3): 775-782


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15722451&dopt=abstract


3. 44900 OI-LS-316; EMBASE-OI-2/23/2005

DAHP synthase from Mycobacterium tuberculosis H37Rv: cloning, expression, and purification of functional enzyme

Rizzi, Caroline, Frazzon, Jeverson, Ely, Fernanda, Weber, Patricia G, da Fonseca, Isabel O, Gallas, Michelle, Oliveira, Jaim S, Mendes, Maria A, de Souza, Bibiana M, and Palma, Mario S

Protein Expression and Purification 2005. 40(1): 23-30


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WPJ-4F00RT8-1/2/d26e8c36daf69be29a6e9168e5c2f605


4. 44901 OI-LS-316; PUBMED-OI-2/23/2005

Study of anticandidal activity of carvacrol and eugenol in vitro and in vivo

Chami, N, Bennis, S, Chami, F, Aboussekhra, A, and Remmal, A

Oral Microbiol Immunol 2005. 20(2): 106-111


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15720571&dopt=abstract


5. 44902 OI-LS-316; PUBMED-OI-2/23/2005

Laboratory approaches to the diagnosis of hepatitis C virus infection

Jerome, KR and Gretch, DR

Minerva Gastroenterol Dietol 2004. 50(1): 9-20


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15719002&dopt=abstract



6. 44903 OI-LS-316; EMBASE-OI-2/23/2005

Synthesis of isonicotinic acid N'-arylidene-N-[2-oxo-2-(4-aryl-piperazin-1-yl)-ethyl]-hydrazides as antituberculosis agents

Sinha, Neelima, Jain, Sanjay, Tilekar, Ajay, Upadhayaya, Ram Shankar, Kishore, Nawal, Jana, Gour Hari, and Arora, Sudershan K

Bioorganic & Medicinal Chemistry Letters 2005. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF9-4FJ5XJ4-5/2/5b09c2496690cb2960a3f583fd875fd2


7. 44904 OI-LS-316; PUBMED-OI-2/23/2005

Novel [2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-d-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide) Derivatives with Anti-HIV-1 and Anti-Human-Cytomegalovirus Activity

de Castro, S, Lobaton, E, Perez-Perez, MJ, San-Felix, A, Cordeiro, A, Andrei, G, Snoeck, R, De Clercq, E, Balzarini, J, Camarasa, MJ, and Velazquez, S

J Med Chem 2005. 48(4): 1158-1168


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15715482&dopt=abstract


8. 44905 OI-LS-316; EMBASE-OI-2/23/2005

Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure

Yamazaki, Kazuo, Kaneko, Yasushi, Suwa, Kie, Ebara, Shinji, Nakazawa, Kyoko, and Yasuno, Kazuhiro

Bioorganic & Medicinal Chemistry 2005. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF8-4FH0D6M-2/2/af50e1883f94ddf2d2ca1cfe5ee2336e


9. 44906 OI-LS-316; PUBMED-OI-2/23/2005

Crystal Structure of a Substrate Complex of Mycobacterium tuberculosis beta-Ketoacyl-acyl Carrier Protein Synthase III (FabH) with Lauroyl-coenzyme A

Musayev, F, Sachdeva, S, Neel Scarsdale, J, Reynolds, KA, and Wright, HT

J Mol Biol 2005. 346(5): 1313-1321


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15713483&dopt=abstract


10. 44907 OI-LS-316; PUBMED-OI-2/23/2005

Interferon Regulatory Factor 3-Independent Double-Stranded RNA-Induced Inhibition of Hepatitis C Virus Replicons in Human Embryonic Kidney 293 Cells

Ali, S and Kukolj, G

J Virol 2005 . 79(5): 3174-3178


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15709037&dopt=abstract



11. 44908 OI-LS-316; EMBASE-OI-2/23/2005

Antibacterial and antifungal activity of pinosylvin, a constituent of pine

Lee, SK, Lee, HJ, Min, HY, Park, EJ, Lee, KM, Ahn, YH, Cho, YJ, and Pyee, JH

Fitoterapia 2005. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6VSC-4FG4V7X-3/2/0daca8f1ad64b0db160dda433f3d03d5


12. 44909 OI-LS-316; PUBMED-OI-2/23/2005

Establishment of a subgenomic replicon for bovine viral diarrhea virus in huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response

Horscroft, N, Bellows, D, Ansari, I, Lai, VC, Dempsey, S, Liang, D, Donis, R, Zhong, W, and Hong, Z

J Virol 2005 . 79(5): 2788-2796


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15708997&dopt=abstract


13. 44910 OI-LS-316; EMBASE-OI-2/23/2005

Synthesis and antimycobacterial activities of glycosylated amino alcohols and amines

Katiyar, D, Tiwari, VK, Tewari, N, Verma, SS, Sinha, S, Gaikwad, A, Srivastava, A, Chaturvedi, V, Srivastava, R, Srivastava, BS, and Tripathi, RP

European Journal of Medicinal Chemistry 2005. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6VKY-4FCRFPD-2/2/3467d5e1ce6cf68499fdf8a276931500


14. 44911 OI-LS-316; PUBMED-OI-2/23/2005

(1)H and (13)C NMR characterization of pyridinium-type isoniazid-NAD adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis

Broussy, S, Bernardes-Genisson, V, Coppel, Y, Quemard, A, Bernadou, J, and Meunier, B

Org Biomol Chem 2005. 3(4): 670-673


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15703806&dopt=abstract


15. 44912 OI-LS-316; PUBMED-OI-2/23/2005

The OtsAB pathway is essential for trehalose biosynthesis in mycobacterium tuberculosis

Murphy, HN, Stewart, GR, Mischenko, VV, Apt, AS, Harris, R, McAlister, MS, Driscoll, PC, Young, DB, and Robertson, BD

J Biol Chem 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15703182&dopt=abstract



16. 44913 OI-LS-316; PUBMED-OI-2/23/2005

A hybrid between the antifungal azole eberconazole and the alkaloid onychine

Dombeck, F and Bracher, F

Pharmazie 2005. 60(1): 5-7


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15700771&dopt=abstract


17. 44914 OI-LS-316; PUBMED-OI-2/23/2005

Identification of inhibitors for a virally encoded protein kinase by 2 different screening systems: in vitro kinase assay and in-cell activity assay

Mett, H, Holscher, K, Degen, H, Esdar, C, De Neumann, BF, Flicke, B, Freudenreich, T, Holzer, G, Schinzel, S, Stamminger, T, Stein-Gerlach, M, Marschall, M, and Herget, T

J Biomol Screen 2005. 10(1): 36-45


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15695342&dopt=abstract


18. 44915 OI-LS-316; EMBASE-OI-2/23/2005

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines

Pratt, John K, Donner, Pamela, McDaniel, Keith F, Maring, Clarence J, Kati, Warren M, Mo, Hongmei, Middleton, Tim, Liu, Yaya, Ng, Teresa, and Xie, Qinghua

Bioorganic & Medicinal Chemistry Letters 2005. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF9-4FJ5XJ4-7/2/f484d1c313f9acfc8b877c4811b2c86d


19. 44916 OI-LS-316; EMBASE-OI-2/23/2005

Design and synthesis of a potent macrocyclic 1,6-napthyridine anti-human cytomegalovirus (HCMV) inhibitors

Falardeau, Guy, Lachance, Hugo, St-Pierre, Annie, Yannopoulos, Constantin G, Drouin, Marc, Bedard, Jean, and Chan, Laval

Bioorganic & Medicinal Chemistry Letters 2005. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF9-4FFGJ50-7/2/9a87fc85f79b22dc244fb6e2c58702be


20. 44917 OI-LS-316; EMBASE-OI-2/23/2005

Effect of the anti-cytomegalovirus (CMV) drug maribavir (MB) on the activities of cytochrome p450 (CYP) 1A2, 2C9, 2C19, 2D6, 3A, N-ACETYLTRANSFERASE-2 (NAT-2), and xanthine oxidase (XO) as assessed by the cooperstown 5+1 drug cocktail

Ma, JD, Nafziger, AN, Villano, SA, Gaedigk, A, Victory, J, and Bertino, JS

Clinical Pharmacology & Therapeutics 2005. 77(2): P19


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WCN-4FDMRBG-2K/2/2c19d48c06a4524cc168e7bcb15ed5ca



21. 44918 OI-LS-316; PUBMED-OI-2/23/2005

Mutations responsible for Mycobacterium tuberculosis isoniazid resistance in Italy

Rindi, L, Bianchi, L, Tortoli, E, Lari, N, Bonanni, D, and Garzelli, C

Int J Tuberc Lung Dis 2005. 9(1): 94-97


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15675557&dopt=abstract


22. 44919 OI-LS-316; PUBMED-OI-2/23/2005

Assays for glucosidase inhibitors with potential antiviral activities: secreted alkaline phosphatase as a surrogate marker

Norton, PA, Conyers, B, Gong, Q, Steel, LF, Block, TM, and Mehta, AS

J Virol Methods 2005. 124(1-2): 167-172


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15664065&dopt=abstract


23. 44920 OI-LS-316; WOS-OI-2/13/2005

Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide

Mossa, JS, El-Feraly, FS, and Muhammad, I

PHYTOTHERAPY RESEARCH 2004. 18(11): 934-937, 4


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226394300014


24. 44921 OI-LS-316; WOS-OI-2/13/2005

Intranasal application of lentinan enhances bactericidal activity of rat alveolar macrophages against Mycobacterium tuberculosis

Markova, N, Michailova, L, Kussovski, V, Jourdanova, M, and Radoucheva, T

PHARMAZIE 2005. 60(1): 42-48, 7


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226409400008


25. 44922 OI-LS-316; WOS-OI-2/13/2005

Induction of colony-stimulating factors by a 30-kDa secretory protein of Mycobacterium tuberculosis H37Rv

Kaur, S, Kaur, H, and Singh, PP

EUROPEAN CYTOKINE NETWORK 2004. 15(4): 327-338, 12


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226373400007


26. 44923 OI-LS-316; WOS-OI-2/13/2005

Fatty acid synthesis as a target for antimalarial drug discovery

Lu, JZQ, Lee, PJ, Waters, NC, and Prigge, ST

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 2005. 8(1): 15-26, 12


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226436400003



27. 44924 OI-LS-316; WOS-OI-2/13/2005

Streamlining drug discovery informatics: Accelerating the flow from gene to structure to pre-clinical candidate

Artis, DR

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004. 227: U679-1


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000223655602471


28. 44925 OI-LS-316; WOS-OI-2/20/2005

Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses

Lee, MY, Park, CB, Dordick, JS, and Clark, DS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2005. 102(4): 983-987, 5


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226617900007


29. 44926 OI-LS-316; WOS-OI-2/20/2005

Bioactive carbohydrates and recently discovered analogues chemotherapeutics

Wrodnigg, TM and Sprenger, FKF

MINI-REVIEWS IN MEDICINAL CHEMISTRY 2004. 4(4): 437-459, 23


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226486800010


30. 44927 OI-LS-316; WOS-OI-2/20/2005

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

Leyssen, P, Balzarini, J, De Clercq, E , and Neyts, J

JOURNAL OF VIROLOGY 2005. 79(3): 1943-1947, 5


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226634300061


31. 44928 OI-LS-316; WOS-OI-2/20/2005

NF-kappa B activation can mediate inhibition of human cytomegalovirus replication

Eickhoff, JE and Cotten, M

JOURNAL OF GENERAL VIROLOGY 2005. 86: 285-295, 11


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226738500005


32. 44929 OI-LS-316; WOS-OI-2/20/2005

Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains

Saeij, JPJ, Boyle, JP, Grigg, ME, Arrizabalaga, G, and Boothroyd, JC

INFECTION AND IMMUNITY 2005. 73(2): 695-702, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000226731700004


33. 44930 OI-LS-316; WOS-OI-2/20/2005

Practical synthesis of a potent hepatitis C virus RNA replication inhibitor

Xu, F, Waters, M, Bio, MM, Savary, K, Cowden, C, Yang, CH, Reamer, RA, Buck, E, Song, ZGJ, Williams, JM, Tschaen, DM, Volante, RP, Grabowski, EJJ, and Tillyer, R

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004. 228: U121-1


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000223713800588


34. 44931 OI-LS-316; WOS-OI-2/20/2005

Synthesis of a proposed inhibitor of human cytomegalovirus (HCMV) using a tandem chain extension-aldol reaction approach

Lin, WM, Theberge, CR, and Zercher, CK

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004. 228: U133-1


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000223713800661


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