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ONLINE DATABASE SEARCH - OI-LS-329-MEMO

1. 47786 OI-LS-329; PUBMED-OI-8/23/2005

Anidulafungin (eli lilly and co)

Hawser, S

IDrugs 1999. 2(12): 1327-35


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16113965&dopt=abstract


2. 47787 OI-LS-329; SCIFINDER-OI-8/15/2005

Investigations into microsporidian methionine aminopeptidase type 2: A therapeutic target for microsporidiosis

Zhang, Hong, Huang, Huan, Cali, Ann, Takvorian, Peter M, Feng, Xiaochuan, Zhou, Ghou, and Weiss, Louis M

Folia Parasitologica 2005. 52(1/2): 182-192


3. 47788 OI-LS-329; PUBMED-OI-8/23/2005

Hepatitis C virus NS3-4A serine protease inhibitors: Use of a P(2)-P(1) cyclopropyl alanine combination for improved potency

Bogen, S, Saksena, AK, Arasappan, A, Gu, H, Njoroge, FG, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Prongay, A, and Madison, V

Bioorg Med Chem Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16112862&dopt=abstract


4. 47789 OI-LS-329; PUBMED-OI-8/23/2005

Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library

Choi, KJ, Yu, YG, Hahn, HG, Choi, JD, and Yoon, MY

FEBS Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16111681&dopt=abstract


5. 47790 OI-LS-329; PUBMED-OI-8/23/2005

Identification of the Mycobacterium tuberculosis SUF Machinery as the Exclusive Mycobacterial System of [Fe-S] Cluster Assembly: Evidence for Its Implication in the Pathogen's Survival

Huet, G, Daffe, M, and Saves, I

J Bacteriol 2005. 187(17): 6137-46


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16109955&dopt=abstract



6. 47791 OI-LS-329; SCIFINDER-OI-8/15/2005

Antimicrosporidial activity of (fluoro)quinolones in vitro and in vivo

Didier, Elizabeth S, Bowers, Lisa, Stovall, Mary E, Kuebler, Dorothy, Mittleider, Derek, Brindley, Paul J, and Didier, Peter J

Folia Parasitologica 2005. 52(1/2): 173-181


7. 47792 OI-LS-329; SCIFINDER-OI-8/15/2005

Encephalitozoon cuniculi mRNA Cap (Guanine N-7) Methyltransferase: methyl acceptor specificity, inhibition by S-adenosylmethionine analogs, and structure-guided mutational analysis

Hausmann, Stephane, Zheng, Sushuang, Fabrega, Carme, Schneller, Stewart W, Lima, Christopher D, and Shuman, Stewart

Journal of Biological Chemistry 2005. 280(21): 20404-20412


8. 47793 OI-LS-329; PUBMED-OI-8/23/2005

New antifungal agents

Kauffman, CA

Semin Respir Crit Care Med 2004. 25(2): 233-9


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16088465&dopt=abstract


9. 47794 OI-LS-329; PUBMED-OI-8/23/2005

Novel inhibitors of the hepatitis C virus NS3 proteinase

Bennett, F, Liu, YT, Saksena, AK, Arasappan, A, Butkiewicz, N, Dasmahapatra, B, Pichardo, JS, Njoroge, FG, Patel, NM, Huang, Y, and Yang, X

Bioorg Med Chem Lett 2005. 15(19): 4275-8


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16087334&dopt=abstract


10. 47795 OI-LS-329; PUBMED-OI-8/23/2005

Pharmacoproteomic Effects of Isoniazid, Ethambutol and SQ109 on Mycobacterium tuberculosis H37Rv

Jia, L, Coward, L, Gorman, GS, Noker, PE, and Tomaszewsky, JE

J Pharmacol Exp Ther 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16085758&dopt=abstract


11. 47796 OI-LS-329; PUBMED-OI-8/23/2005

Toxoplasma gondii: Microneme protein MIC2

Brossier, F and David, Sibley L

Int J Biochem Cell Biol 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16084754&dopt=abstract



12. 47797 OI-LS-329; PUBMED-OI-8/23/2005

Pneumocystis pneumonia: an update

Sritangratanakul, S, Nuchprayoon, S, and Nuchprayoon, I

J Med Assoc Thai 2004. 87 Suppl 2: S309-17


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16083208&dopt=abstract


13. 47798 OI-LS-329; PUBMED-OI-8/23/2005

In vitro susceptibilities of clinical isolates of Candida species, Cryptococcus neoformans, and Aspergillus species to itraconazole: global survey of 9,359 isolates tested by clinical and laboratory standards institute broth microdilution methods

Pfaller, MA, Boyken, L, Hollis, RJ, Messer, SA, Tendolkar, S, and Diekema, DJ

J Clin Microbiol 2005. 43(8): 3807-10


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16081915&dopt=abstract


14. 47799 OI-LS-329; PUBMED-OI-8/23/2005

Molecular design of two sterol 14alpha-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole

Rupp, B, Raub, S, Marian, C, and Holtje, HD

J Comput Aided Mol Des 2005. 19(3): 149-63


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16059669&dopt=abstract


15. 47800 OI-LS-329; PUBMED-OI-8/23/2005

A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis

Morgan, M, Kalantri, S, Flores, L, and Pai, M

BMC Infect Dis 2005. 5: 62


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16050959&dopt=abstract


16. 47801 OI-LS-329; SCIFINDER-OI-8/15/2005

Preparation of 2-(azolylmethyl)-4-(piperazinylphenoxymethyl)-1,3-dioxolanes as antifungals with reduced interaction with metabolic cytochromes

Pinori, Massimo, Lattanzio, Maria, Modena, Daniela, and Mascagni, Paolo

PATENT: WO 2005040156 ISSUE DATE: 20050506

APPLICATION: 2004 PP: 27 pp.

ASSIGNEE: (Italfarmaco S.p.A., Italy



17. 47802 OI-LS-329; SCIFINDER-OI-8/15/2005

In-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide-derived Schiff's bases and their metal complexes

Chohan, Zahid H, Mahmood-Ul-Hassan, Khan, Khalid M, and Supuran, Claudiu T

Journal of Enzyme Inhibition and Medicinal Chemistry 2005. 20(2): 183-188


18. 47803 OI-LS-329; WOS-OI-8/14/2005

Drugs against tuberculose: Past, present and future

de Souza, MVN and Vasconcelos, TRA

QUIMICA NOVA 2005. 28(4): 678-682, 5


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230649400022


19. 47804 OI-LS-329; WOS-OI-8/14/2005

Slow-onset feedback inhibition: Inhibition of Mycobacterium tuberculosis alpha-isopropylmalate synthase by L-leucine

de Carvalho, LPS, Argyrou, A, and Blanchard, JS

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2005. 127(28): 10004-10005, 2


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230657900029


20. 47805 OI-LS-329; SCIFINDER-OI-8/15/2005

Synthesis of 2,4-bis(alkylamino)pyrimidines and their use as antimicrobials

Marquais-Bienewald, Sophie, Hoelzl, Werner, Preuss, Andrea, and Mehlin, Andreas

PATENT: WO 2005011758 ISSUE DATE: 20050210

APPLICATION: 2004 PP: 38 pp.

ASSIGNEE: (Ciba Specialty Chemicals Holding Inc., Switz.


21. 47806 OI-LS-329; SCIFINDER-OI-8/15/2005

Cationic substituted benzofurans as antimicrobial agents

Werbovetz, Karl, Franzblau, Scott Gary, Tidwell, Richard R, Bakunova, Svetlana, and Bakunov, Stanislav

PATENT: WO 2005055935 ISSUE DATE: 20050623

APPLICATION: 2004 PP: 146 pp.

ASSIGNEE: (The University of North Carolina at Chapel Hill, USA


22. 47807 OI-LS-329; WOS-OI-8/14/2005

3-nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: Is 3-NPA in some plants produced by endophytes?

Chomeheon, P, Wiyakrutta, S, Sriubolmas, N, Ngamrojanavanich, N, Isarangkul, D, and Kittakoop, P

JOURNAL OF NATURAL PRODUCTS 2005. 68(7): 1103-1105, 3


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230706800027


23. 47808 OI-LS-329; WOS-OI-8/14/2005

5 '-Homoneplanocin A inhibits hepatitis B and hepatitis C

Yang, MM, Schneller, SW, and Korba, B

JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(15): 5043-5046, 4


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230800300032



24. 47809 OI-LS-329; SCIFINDER-OI-8/15/2005

Synthesis of some new thiosemicarbazide and 1,3,4-thiadiazole heterocycles bearing benzo[b]thiophene nucleus as a potent antitubercular and antimicrobial agents

Vasoya, SL, Paghdar, DJ, Chovatia, PT, and Joshi, HS

Journal of Sciences, Islamic Republic of Iran 2005. 16(1): 33-36


25. 47810 OI-LS-329; SCIFINDER-OI-8/15/2005

Synthesis of purinyl homo-carbonucleoside derivatives of 2-benzylcyclopenta[c]pyrazol

Garcia, Marcos D, Caamano, Olga, Fernandez, Franco, Lopez, Carmen, and De Clercq, Erick

Synthesis 2005.(6): 925-932


26. 47811 OI-LS-329; WOS-OI-8/14/2005

High-throughput screening-driven lead discovery: Meeting the challenges of finding new therapeutics

Posner, BA

CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 2005. 8(4 ): 487-494, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230330200009


27. 47812 OI-LS-329; WOS-OI-8/14/2005

The World Health Organization/International Union against Tuberculosis and Lung Disease Global Project on Surveillance for Anti-Tuberculosis Drug Resistance: A model for other infectious diseases

Aziz, MA and Wright, A

CLINICAL INFECTIOUS DISEASES 2005. 41: S258-S262, 5


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230611300008


28. 47813 OI-LS-329; WOS-OI-8/14/2005

Investigation of glycine alpha-ketoamide HCVNS3 protease inhibitors: Effect of carboxylic acid isosteres

Han, W, Jiang, XJ, Hu, ZL, Wasserman, ZR, and Decicco, CP

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2005. 15(15): 3487-3490, 4


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230627800002


29. 47814 OI-LS-329; WOS-OI-8/21/2005

The ultimate model organism: progress in experimental medicine

Littman, BH and Williams, SA

NATURE REVIEWS DRUG DISCOVERY 2005. 4(8): 631-638, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230957400015


30. 47815 OI-LS-329; WOS-OI-8/21/2005

Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol

Kremer, L, de Chastellier, C, Dobson, G, Gibson, KJC, Bifani, P, Balor, S, Gorvel, JP, Locht, C, Minnikin, DE, and Besra, GS

MOLECULAR MICROBIOLOGY 2005. 57(4): 1113-1126, 14


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230888300020



31. 47816 OI-LS-329; WOS-OI-8/21/2005

The hepatitis C virus replicon system: From basic research to clinical application

Bartenschlager, R

JOURNAL OF HEPATOLOGY 2005. 43(2): 210-216, 7


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230803900004


32. 47817 OI-LS-329; WOS-OI-8/21/2005

A virtual screening approach for thymidine monophosphate kinase inhibitors as antitubercular agents based on docking and pharmaeophore models

Gopalakrishnan, B, Aparna, V, Jeevan, J, Ravi, M, and Desiraju, GR

JOURNAL OF CHEMICAL INFORMATION AND MODELING 2005. 45(4): 1101-1108, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230864300032


33. 47818 OI-LS-329; WOS-OI-8/21/2005

Synthesis and antifungal activity of naphthalene-1,4-diones modified at positions 2, 3, and 5

Ryu, CK and Chae, MJ

ARCHIVES OF PHARMACAL RESEARCH 2005. 28(7): 750-755, 6


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230856700002


34. 47819 OI-LS-329; WOS-OI-8/21/2005

Update on tuberculosis and other opportunistic infections associated with biologic therapies

Winthrop, KL

ANNALS OF THE RHEUMATIC DISEASES 2005. 64: 2-3, 2


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000229909100007


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