ONLINE DATABASE SEARCH - OI-LS-338-MEMO
1. 48309 OI-LS-338; PUBMED-OI-12/27/2005
The discovery of finger loop inhibitors of the hepatitis C virus NS5B polymerase: Status and prospects for novel HCV therapeutics
Beaulieu, PL
IDrugs 2006. 9(1): 39-43
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16374732&dopt=abstract
2. 48310 OI-LS-338; PUBMED-OI-12/27/2005
Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication
Clark, JL, Mason, JC, Hollecker, L, Stuyver, LJ, Tharnish, PM, McBrayer, TR, Otto, MJ, Furman, PA, Schinazi, RF, and Watanabe, KA
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16368235&dopt=abstract
3. 48311 OI-LS-338; EMBASE-OI-12/27/2005
Antimicrobial activity of flavonoids
Cushnie, TPTim and Lamb, Andrew J
International Journal of Antimicrobial Agents 2005. 26(5): 343-356
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T7H-4HC7708-2/2/d7ff23eb5b8540e4bb1f9ab03e0b5e6c
4. 48312 OI-LS-338; PUBMED-OI-12/27/2005
Randomized, double-blind, placebo-controlled study of peginterferon alfa-2a (40KD) plus ribavirin with or without amantadine in treatment-naive patients with chronic hepatitis C genotype 1 infection
Ferenci, P, Formann, E, Laferl, H, Gschwantler, M, Hackl, F, Brunner, H, Hubmann, R, Datz, C, Stauber, R, Steindl-Munda, P, Kessler, HH, Klingler, A, Gangl, A, and For, The Austrian Hepatitis Study Group
J Hepatol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16338019&dopt=abstract
5. 48313 OI-LS-338; PUBMED-OI-12/27/2005
Synthesis and antifungal activity of substituted-10-methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indoles
Tiwari, RK, Verma, AK, Chhillar, AK, Singh, D, Singh, J, Kasi, Sankar V, Yadav, V, Sharma, GL, and Chandra, R
Bioorg Med Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16377197&dopt=abstract
6. 48314 OI-LS-338; PUBMED-OI-12/27/2005
Chronic Hepatitis C Virus Management: 2000-2005 Update (January)
Hughes, CA and Shafran, SD
Ann Pharmacother 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16368925&dopt=abstract
7. 48315 OI-LS-338; PUBMED-OI-12/27/2005
The novel nucleoside analog R1479, 4'-azidocytidine, is a potent inhibitor of NS5B dependent RNA synthesis and HCV replication in cell culture
Klumpp, K, Leveque, V, Le, Pogam S, Ma, H, Jiang, WR, Kang, H, Granycome, C, Singer, M, Laxton, C, Hang, JQ, Sarma, K, Smith, DB, Heindl, D, Hobbs, CJ, Merrett, JH, Symons, J, Cammack, N, Martin, JA, Devos, R, and Najera, I
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16316989&dopt=abstract
8. 48316 OI-LS-338; PUBMED-OI-12/27/2005
Synthesis and antimycobacterial activity of some alkyl [5-(nitroaryl)-1,3,4-thiadiazol-2-ylthio]propionates
Foroumadi, A, Kargar, Z, Sakhteman, A, Sharifzadeh, Z, Feyzmohammadi, R, Kazemi, M, and Shafiee, A
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16359863&dopt=abstract
9. 48317 OI-LS-338; PUBMED-OI-12/27/2005
Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor: Reduced RNA replication fitness and partial rescue by second-site mutations
Yi, M, Tong, X, Skelton, A, Chase, R, Chen, T, Prongay, A, Bogen, SL, Saksena, AK, Njoroge, FG, Veselenak, RL, Pyles, RB, Bourne, N, Malcolm, BA, and Lemon, SM
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16352601&dopt=abstract
10. 48318 OI-LS-338; PUBMED-OI-12/27/2005
The first chemical synthesis of the core structure of the benzoylhydrazine-NAD adduct, a competitive inhibitor of the Mycobacterium tuberculosis enoyl reductase
Broussy, S, Bernardes-Genisson, V, Quemard, A, Meunier, B, and Bernadou, J
J Org Chem 2005. 70(25): 10502-10
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16323864&dopt=abstract
11. 48319 OI-LS-338; PUBMED-OI-12/27/2005
6-Benzylthioinosine analogues: Promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es)
Gupte, A, Buolamwini, JK, Yadav, V, Chu, CK, Naguib, FN, and El, Kouni MH
Biochem Pharmacol 2005. 71(1-2): 69-73
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16310172&dopt=abstract
12. 48320 OI-LS-338; PUBMED-OI-12/27/2005
p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis
Stadthagen, G, Kordulakova, J, Griffin, R, Constant, P, Bottova, I, Barilone, N, Gicquel, B, Daffe, M, and Jackson, M
J Biol Chem 2005. 280(49): 40699-706
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16210318&dopt=abstract
13. 48321 OI-LS-338; WOS-OI-12/18/2005
Acute-phase reactants during murine tuberculosis: Unknown dimensions and new frontiers
Singh, PP and Kaur, S
TUBERCULOSIS 2005. 85(5-6): 303-315, 13
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233674400005
14. 48322 OI-LS-338; WOS-OI-12/18/2005
Structural biology of mycobacterial proteins: The Bangalore effort
Vijayan, M
TUBERCULOSIS 2005. 85(5-6): 357-366, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233674400010
15. 48323 OI-LS-338; WOS-OI-12/18/2005
Attachment and invasion of Toxoplasma gondii and Neospora caninum to epithelial and fibroblast cell lines in vitro
Lei, Y, Davey, M, and Ellis, JT
PARASITOLOGY 2005. 131: 583-590, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233604900001
16. 48324 OI-LS-338; WOS-OI-12/18/2005
Highly lipophilic benzoxazoles with potential antibacterial activity
Vinsova, J, Horak, V, Buchta, V, and Kaustova, J
MOLECULES 2005. 10(7): 783-793, 11
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233710600006
17. 48325 OI-LS-338; EMBASE-OI-12/27/2005
Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3
Ronn, Robert, Sabnis, Yogesh A, Gossas, Thomas, Akerblom, Eva, Helena Danielson, U, Hallberg, Anders, and Johansson, Anja
Bioorganic & Medicinal Chemistry 2006. 14(2): 544-559
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF8-4H877DS-2/2/c217c935922c774b1816e61c4b8c21fe
18. 48326 OI-LS-338; WOS-OI-12/18/2005
Design, synthesis, and microbiological evaluation of new Candida albicans CYP51 inhibitors
Schiaffella, F, Macchiarulo, A, Milanese, L, Vecchiarelli, A, Costantino, G, Pietrella, D, and Fringuelli, R
JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(24): 7658-7666, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233654900016
19. 48327 OI-LS-338; WOS-OI-12/25/2005
Finding new tricks for old drugs: An efficient route for public-sector drug discovery
O'Connor, KA and Roth, BL
NATURE REVIEWS DRUG DISCOVERY 2005. 4(12): 1005-1014, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233774900021
20. 48328 OI-LS-338; WOS-OI-12/25/2005
Gateways to clinical trials
Bayes, M, Rabasseda, X, and Prous, JR
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 2005. 27(8): 569-612, 44
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233873800007
21. 48329 OI-LS-338; WOS-OI-12/25/2005
Mutational and expression analysis of tbnat and its response to isoniazid
Sholto-Douglas-Vernon, C, Sandy, J, Victor, TC, Sim, E, and van, Helden PD
JOURNAL OF MEDICAL MICROBIOLOGY 2005. 54(12): 1189-1197, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233831000011
22. 48330 OI-LS-338; WOS-OI-12/25/2005
Synthesis of reduced xanthatin derivatives and in vitro evaluation of their antifungal activity
Pinel, B, Landreau, A, Seraphin, D, Larcher, G, Bouchara, JP, and Richomme, P
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2005. 20(6): 575-579, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233856200007
23. 48331 OI-LS-338; WOS-OI-12/25/2005
Simultaneous detection of isoniazid, rifampin, and ethambutol resistance of Mycobacterium tuberculosis by a single multiplex allele-specific polymerase chain reaction (PCR) assay
Yang, ZH, Durmaz, R, Yang, D, Gunal, S, Zhang, LX, Foxman, B, Sanic, A, and Marrs, CF
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 2005. 53(3 ): 201-208, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233830600006
24. 48332 OI-LS-338; WOS-OI-12/25/2005
New agents with anti mycobacterial activity
Marco-Contelles, J and Gomez-Sanchez, E
ARCHIV DER PHARMAZIE 2005. 338(11): 562-563, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233783400008