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ONLINE DATABASE SEARCH - OI-LS-338-MEMO

1. 48309 OI-LS-338; PUBMED-OI-12/27/2005

The discovery of finger loop inhibitors of the hepatitis C virus NS5B polymerase: Status and prospects for novel HCV therapeutics

Beaulieu, PL

IDrugs 2006. 9(1): 39-43


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16374732&dopt=abstract


2. 48310 OI-LS-338; PUBMED-OI-12/27/2005

Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Clark, JL, Mason, JC, Hollecker, L, Stuyver, LJ, Tharnish, PM, McBrayer, TR, Otto, MJ, Furman, PA, Schinazi, RF, and Watanabe, KA

Bioorg Med Chem Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16368235&dopt=abstract


3. 48311 OI-LS-338; EMBASE-OI-12/27/2005

Antimicrobial activity of flavonoids

Cushnie, TPTim and Lamb, Andrew J

International Journal of Antimicrobial Agents 2005. 26(5): 343-356


HYPERLINK:

http://www.sciencedirect.com/science/article/B6T7H-4HC7708-2/2/d7ff23eb5b8540e4bb1f9ab03e0b5e6c


4. 48312 OI-LS-338; PUBMED-OI-12/27/2005

Randomized, double-blind, placebo-controlled study of peginterferon alfa-2a (40KD) plus ribavirin with or without amantadine in treatment-naive patients with chronic hepatitis C genotype 1 infection

Ferenci, P, Formann, E, Laferl, H, Gschwantler, M, Hackl, F, Brunner, H, Hubmann, R, Datz, C, Stauber, R, Steindl-Munda, P, Kessler, HH, Klingler, A, Gangl, A, and For, The Austrian Hepatitis Study Group

J Hepatol 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16338019&dopt=abstract


5. 48313 OI-LS-338; PUBMED-OI-12/27/2005

Synthesis and antifungal activity of substituted-10-methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indoles

Tiwari, RK, Verma, AK, Chhillar, AK, Singh, D, Singh, J, Kasi, Sankar V, Yadav, V, Sharma, GL, and Chandra, R

Bioorg Med Chem 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16377197&dopt=abstract



6. 48314 OI-LS-338; PUBMED-OI-12/27/2005

Chronic Hepatitis C Virus Management: 2000-2005 Update (January)

Hughes, CA and Shafran, SD

Ann Pharmacother 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16368925&dopt=abstract


7. 48315 OI-LS-338; PUBMED-OI-12/27/2005

The novel nucleoside analog R1479, 4'-azidocytidine, is a potent inhibitor of NS5B dependent RNA synthesis and HCV replication in cell culture

Klumpp, K, Leveque, V, Le, Pogam S, Ma, H, Jiang, WR, Kang, H, Granycome, C, Singer, M, Laxton, C, Hang, JQ, Sarma, K, Smith, DB, Heindl, D, Hobbs, CJ, Merrett, JH, Symons, J, Cammack, N, Martin, JA, Devos, R, and Najera, I

J Biol Chem 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16316989&dopt=abstract


8. 48316 OI-LS-338; PUBMED-OI-12/27/2005

Synthesis and antimycobacterial activity of some alkyl [5-(nitroaryl)-1,3,4-thiadiazol-2-ylthio]propionates

Foroumadi, A, Kargar, Z, Sakhteman, A, Sharifzadeh, Z, Feyzmohammadi, R, Kazemi, M, and Shafiee, A

Bioorg Med Chem Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16359863&dopt=abstract


9. 48317 OI-LS-338; PUBMED-OI-12/27/2005

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor: Reduced RNA replication fitness and partial rescue by second-site mutations

Yi, M, Tong, X, Skelton, A, Chase, R, Chen, T, Prongay, A, Bogen, SL, Saksena, AK, Njoroge, FG, Veselenak, RL, Pyles, RB, Bourne, N, Malcolm, BA, and Lemon, SM

J Biol Chem 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16352601&dopt=abstract


10. 48318 OI-LS-338; PUBMED-OI-12/27/2005

The first chemical synthesis of the core structure of the benzoylhydrazine-NAD adduct, a competitive inhibitor of the Mycobacterium tuberculosis enoyl reductase

Broussy, S, Bernardes-Genisson, V, Quemard, A, Meunier, B, and Bernadou, J

J Org Chem 2005. 70(25): 10502-10


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16323864&dopt=abstract



11. 48319 OI-LS-338; PUBMED-OI-12/27/2005

6-Benzylthioinosine analogues: Promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es)

Gupte, A, Buolamwini, JK, Yadav, V, Chu, CK, Naguib, FN, and El, Kouni MH

Biochem Pharmacol 2005. 71(1-2): 69-73


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16310172&dopt=abstract


12. 48320 OI-LS-338; PUBMED-OI-12/27/2005

p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis

Stadthagen, G, Kordulakova, J, Griffin, R, Constant, P, Bottova, I, Barilone, N, Gicquel, B, Daffe, M, and Jackson, M

J Biol Chem 2005. 280(49): 40699-706


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16210318&dopt=abstract


13. 48321 OI-LS-338; WOS-OI-12/18/2005

Acute-phase reactants during murine tuberculosis: Unknown dimensions and new frontiers

Singh, PP and Kaur, S

TUBERCULOSIS 2005. 85(5-6): 303-315, 13


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233674400005


14. 48322 OI-LS-338; WOS-OI-12/18/2005

Structural biology of mycobacterial proteins: The Bangalore effort

Vijayan, M

TUBERCULOSIS 2005. 85(5-6): 357-366, 10


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233674400010


15. 48323 OI-LS-338; WOS-OI-12/18/2005

Attachment and invasion of Toxoplasma gondii and Neospora caninum to epithelial and fibroblast cell lines in vitro

Lei, Y, Davey, M, and Ellis, JT

PARASITOLOGY 2005. 131: 583-590, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233604900001


16. 48324 OI-LS-338; WOS-OI-12/18/2005

Highly lipophilic benzoxazoles with potential antibacterial activity

Vinsova, J, Horak, V, Buchta, V, and Kaustova, J

MOLECULES 2005. 10(7): 783-793, 11


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233710600006



17. 48325 OI-LS-338; EMBASE-OI-12/27/2005

Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3

Ronn, Robert, Sabnis, Yogesh A, Gossas, Thomas, Akerblom, Eva, Helena Danielson, U, Hallberg, Anders, and Johansson, Anja

Bioorganic & Medicinal Chemistry 2006. 14(2): 544-559


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF8-4H877DS-2/2/c217c935922c774b1816e61c4b8c21fe


18. 48326 OI-LS-338; WOS-OI-12/18/2005

Design, synthesis, and microbiological evaluation of new Candida albicans CYP51 inhibitors

Schiaffella, F, Macchiarulo, A, Milanese, L, Vecchiarelli, A, Costantino, G, Pietrella, D, and Fringuelli, R

JOURNAL OF MEDICINAL CHEMISTRY 2005. 48(24): 7658-7666, 9


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233654900016


19. 48327 OI-LS-338; WOS-OI-12/25/2005

Finding new tricks for old drugs: An efficient route for public-sector drug discovery

O'Connor, KA and Roth, BL

NATURE REVIEWS DRUG DISCOVERY 2005. 4(12): 1005-1014, 10


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233774900021


20. 48328 OI-LS-338; WOS-OI-12/25/2005

Gateways to clinical trials

Bayes, M, Rabasseda, X, and Prous, JR

METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 2005. 27(8): 569-612, 44


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233873800007


21. 48329 OI-LS-338; WOS-OI-12/25/2005

Mutational and expression analysis of tbnat and its response to isoniazid

Sholto-Douglas-Vernon, C, Sandy, J, Victor, TC, Sim, E, and van, Helden PD

JOURNAL OF MEDICAL MICROBIOLOGY 2005. 54(12): 1189-1197, 9


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233831000011


22. 48330 OI-LS-338; WOS-OI-12/25/2005

Synthesis of reduced xanthatin derivatives and in vitro evaluation of their antifungal activity

Pinel, B, Landreau, A, Seraphin, D, Larcher, G, Bouchara, JP, and Richomme, P

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2005. 20(6): 575-579, 5


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233856200007


23. 48331 OI-LS-338; WOS-OI-12/25/2005

Simultaneous detection of isoniazid, rifampin, and ethambutol resistance of Mycobacterium tuberculosis by a single multiplex allele-specific polymerase chain reaction (PCR) assay

Yang, ZH, Durmaz, R, Yang, D, Gunal, S, Zhang, LX, Foxman, B, Sanic, A, and Marrs, CF

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 2005. 53(3 ): 201-208, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233830600006


24. 48332 OI-LS-338; WOS-OI-12/25/2005

New agents with anti mycobacterial activity

Marco-Contelles, J and Gomez-Sanchez, E

ARCHIV DER PHARMAZIE 2005. 338(11): 562-563, 2


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233783400008


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