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1. 48505 OI-LS-342; EMBASE-OI-2/21/2006

Searching for a new anti-HCV therapy: Synthesis and properties of tropolone derivatives

Boguszewska-Chachulska, Anna M, Krawczyk, Mariusz, Najda, Andzelika, Kopanska, Katarzyna, Stankiewicz-Drogon, Anna, Zagorski-Ostoja, Wlodzimierz, and Bretner, Maria

Biochemical and Biophysical Research Communications 2006. 341(2): 641-647


2. 48506 OI-LS-342; PUBMED-OI-2/21/2006

Purification and Characterization of Mycobacterium tuberculosis Indole-3-glycerol Phosphate Synthase

Yang, Y, Zhang, M, Zhang, H, Lei, J, Jin, R, Xu, S, Bao, J, Zhang, L, and Wang, H

Biochemistry (Mosc) 2006. 71 Suppl 1: S38-S43


3. 48507 OI-LS-342; PUBMED-OI-2/21/2006

Mycobacterium tuberculosis Cells Growing in Macrophages Are Filamentous and Deficient in FtsZ Rings

Chauhan, A, Madiraju, MV, Fol, M, Lofton, H, Maloney, E, Reynolds, R, and Rajagopalan, M

J Bacteriol 2006. 188(5): 1856-65


4. 48508 OI-LS-342; PUBMED-OI-2/21/2006

Screening for antimicrobial activity of ten medicinal plants used in Colombian folkloric medicine: A possible alternative in the treatment of non-nosocomial infections

Rojas, JJ, Ochoa, VJ, Ocampo, SA, and Munoz, JF

BMC Complement Altern Med 2006. 6(1): 2


5. 48509 OI-LS-342; EMBASE-OI-2/21/2006

Synthesis and antimycobacterial activity of some alkyl [5-(nitroaryl)-1,3,4-thiadiazol-2-ylthio]propionates

Foroumadi, Alireza, Kargar, Zahra, Sakhteman, Amirhossein, Sharifzadeh, Zahra, Feyzmohammadi, Robabeh, Kazemi, Mahnoush, and Shafiee, Abbas

Bioorganic & Medicinal Chemistry Letters 2006. 16(5): 1164-1167


6. 48510 OI-LS-342; PUBMED-OI-2/21/2006

Identification of Isoflavone Derivatives as Effective Anticryptosporidial Agents in Vitro and in Vivo

Stachulski, AV, Berry, NG, Lilian, Low AC, Moores, SL, Row, E, Warhurst, DC, Adagu, IS, and Rossignol, JF

J Med Chem 2006. 49(4): 1450-1454


7. 48511 OI-LS-342; EMBASE-OI-2/21/2006

Investigation of the mechanism of action of 3-(4-bromophenyl)-5-acyloxymethyl-2,5-dihydrofuran-2-one against Candida albicans by flow cytometry

Vale-Silva, Luis A, Buchta, Vladimir, Vokurkova, Doris, and Pour, Milan

Bioorganic & Medicinal Chemistry Letters 2006. In Press, Corrected Proof


8. 48512 OI-LS-342; EMBASE-OI-2/21/2006

Substituent effect of fluorine atoms in the 2,4-difluorophenyl group on antifungal activity of CS-758

Kagoshima, Yoshiko and Konosu, Toshiyuki

Journal of Fluorine Chemistry 2006. In Press, Corrected Proof


9. 48513 OI-LS-342; PUBMED-OI-2/21/2006

Towards Species-specific Antifolates

Chan, DC and Anderson, AC

Curr Med Chem 2006. 13(4): 377-98


10. 48514 OI-LS-342; PUBMED-OI-2/21/2006

Synthesis and potent antimicrobial activities of some novel retinoidal monocationic benzimidazoles

Ates-Alagoz, Z, Alp, M, Kus, C, Yildiz, S, Buyukbingol, E, and Goker, H

Arch Pharm (Weinheim) 2006. 339(2): 74-80


11. 48515 OI-LS-342; EMBASE-OI-2/21/2006

In vitro interactions of anidulafungin with azole antifungals, amphotericin B and 5-fluorocytosine against Candida species

Karlowsky, James A, Hoban, Daryl J, Zhanel, George G, and Goldstein, Beth P

International Journal of Antimicrobial Agents 2006. 27(2): 174-177


12. 48516 OI-LS-342; PUBMED-OI-2/21/2006

Steady-state kinetics and inhibitory action of antitubercular phenothiazines on mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2)

Yano, T, Li, LS, Weinstein, E, Teh, JS, and Rubin, H

J Biol Chem 2006.


13. 48517 OI-LS-342; EMBASE-OI-2/21/2006

Serum amyloid P-component in murine tuberculosis: induction kinetics and intramacrophage Mycobacterium tuberculosis growth inhibition in vitro

Singh, Prati Pal and Kaur, Sukhraj

Microbes and Infection 2006. 8(2): 541-551


14. 48518 OI-LS-342; PUBMED-OI-2/21/2006

Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate

Hu, G, Lin, G, Wang, M, Dick, L, Xu, RM, Nathan, C, and Li, H

Mol Microbiol 2006. 59(5): 1417-28


15. 48519 OI-LS-342; PUBMED-OI-2/21/2006

Synthesis of pyrazinamide Mannich bases and its antitubercular properties

Sriram, D, Yogeeswari, P, and Reddy, SP

Bioorg Med Chem Lett 2006.


16. 48520 OI-LS-342; PUBMED-OI-2/21/2006

Medicinal plants used by Tanzanian traditional healers in the management of Candida infections

Runyoro, DK, Ngassapa, OD, Matee, MI, Joseph, CC, and Moshi, MJ

J Ethnopharmacol 2006.



17. 48521 OI-LS-342; PUBMED-OI-2/21/2006

SAR and mode of action of novel non-nucleoside inhibitors of Hepatitis C NS5b RNA polymerase

Powers, JP, Piper, DE, Li, Y, Mayorga, V, Anzola, J, Chen, JM, Jaen, JC, Lee, G, Liu, J, Peterson, MG, Tonn, GR, Ye, Q, Walker, NP, and Wang, Z

J Med Chem 2006. 49(3): 1034-46


18. 48522 OI-LS-342; PUBMED-OI-2/21/2006

Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles

Chen, KX, Njoroge, FG, Arasappan, A, Venkatraman, S, Vibulbhan, B, Yang, W, Parekh, TN, Pichardo, J, Prongay, A, Cheng, KC, Butkiewicz, N, Yao, N, Madison, V, and Girijavallabhan, V

J Med Chem 2006. 49(3): 995-1005


19. 48523 OI-LS-342; PUBMED-OI-2/21/2006

3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones , potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase

Tedesco, R, Shaw, AN, Bambal, R, Chai, D, Concha, NO, Darcy, MG, Dhanak, D, Fitch, DM, Gates, A, Gerhardt, WG, Halegoua, DL, Han, C, Hofmann, GA, Johnston, VK, Kaura, AC, Liu, N, Keenan, RM, Lin-Goerke, J, Sarisky, RT, Wiggall, KJ, Zimmerman, MN, and Duffy, KJ

J Med Chem 2006. 49(3): 971-83


20. 48524 OI-LS-342; EMBASE-OI-2/21/2006

Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase

Gopalsamy, Ariamala, Shi, Mengxiao, Ciszewski, Gregory, Park, Kaapjoo, Ellingboe, John W, Orlowski, Mark, Feld, Boris, and Howe, Anita YM

Bioorganic & Medicinal Chemistry Letters 2006. In Press, Corrected Proof


21. 48525 OI-LS-342; EMBASE-OI-2/21/2006

Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole

Ishida, Tomio, Suzuki, Takayoshi, Hirashima, Shintaro, Mizutani, Kenji, Yoshida, Atsuhito, Ando, Izuru, Ikeda, Satoru, Adachi, Tsuyoshi, and Hashimoto, Hiromasa

Bioorganic & Medicinal Chemistry Letters 2006. In Press, Corrected Proof


22. 48526 OI-LS-342; EMBASE-OI-2/21/2006

An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

Evans, Karen A, Chai, Deping, Graybill, Todd L, Burton, George, Sarisky, Robert T, Lin-Goerke, Juili, Johnston, Victor K, and Rivero, Ralph A

Bioorganic & Medicinal Chemistry Letters 2006. In Press, Corrected Proof


23. 48527 OI-LS-342; PUBMED-OI-2/21/2006

Hexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis

Widmer, F, Wright, LC, Obando, D, Handke, R, Ganendren, R, Ellis, DH, and Sorrell, TC

Antimicrob Agents Chemother 2006. 50(2): 414-21


24. 48528 OI-LS-342; EMBASE-OI-2/21/2006

The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo

Kaptein, Suzanne JF, Efferth, Thomas, Leis, Martina, Rechter, Sabine, Auerochs, Sabrina, Kalmer, Martina, Bruggeman, Cathrien A, Vink, Cornelis, Stamminger, Thomas, and Marschall, Manfred

Antiviral Research 2006. 69(2): 60-69


25. 48529 OI-LS-342; EMBASE-OI-2/21/2006

Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase

Ding, Yili, Girardet, Jean-Luc, Smith, Kenneth L, Larson, Gary, Prigaro, Brett, Wu, Jim Z, and Yao, Nanhua

Bioorganic Chemistry 2006. 34(1): 26-38


26. 48530 OI-LS-342; EMBASE-OI-2/21/2006

Novel Inhibitors of Hepatitis C Virus RNA-dependent RNA Polymerases

Lee, Gary, Piper, Derek E, Wang, Zhulun, Anzola, John, Powers, Jay, Walker, Nigel, and Li, Yang

Journal of Molecular Biology 2006. In Press, Corrected Proof


27. 48531 OI-LS-342; WOS-OI-2/12/2006

Mechanisms of action of ribavirin against distinct viruses

Graci, JD and Cameron, CE

REVIEWS IN MEDICAL VIROLOGY 2006. 16(1): 37-48, 12


28. 48532 OI-LS-342; WOS-OI-2/12/2006

Potent 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid-based macrocyclic inhibitors of hepatitis C virus NS3 protease

Chen, KX, Njoroge, FG, Pichardo, J, Prongay, A, Butkiewicz, N, Yao, N, Madison, V, and Girijavallabhan, V

JOURNAL OF MEDICINAL CHEMISTRY 2006. 49(2): 567-574, 8


29. 48533 OI-LS-342; WOS-OI-2/12/2006

Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts

Ng, CKL, Obando, D, Widmer, F, Wright, LC, Sorrell, TC, and Jolliffe, KA

JOURNAL OF MEDICINAL CHEMISTRY 2006. 49(2): 811-816, 6


30. 48534 OI-LS-342; WOS-OI-2/12/2006

Synthesis and in vitro antitubercular activity of some 1-[(4-sub)phenyl]-3-(4-{1-[(pyridine-4-carbonyl) hydrazono]ethyl}phenyl)thiourea

Sriram, D, Yogeeswari, P, and Madhu, K



31. 48535 OI-LS-342; WOS-OI-2/19/2006

The role of an amphiphilic capping group in covalent and non-covalent dipeptide inhibitors of HCVNS3 serine protease

Colarusso, S, Gerlach, B, Giuliano, C, Koch, U, Matassa, VG, and Narjes, F

LETTERS IN DRUG DESIGN & DISCOVERY 2005. 2(2): 113-117, 5


32. 48536 OI-LS-342; WOS-OI-2/19/2006

P1 and P1 ' optimization of [3,4]-bicycloproline P2 incorporated tetrapeptidyl alpha-ketoamide based HCV protease inhibitors

Chen, SH, Lamar, J, Yip, Y, Victor, F, Johnson, RB, Wang, QM, Glass, JI, Heinz, B, Colacino, J, Guo, DQ, Tebbe, M, and Munroe, JE

LETTERS IN DRUG DESIGN & DISCOVERY 2005. 2(2): 118-123, 6


33. 48537 OI-LS-342; WOS-OI-2/19/2006

Phenyldihydroxypyrimidines as HCVNS5B RNA dependent RNA polymerase inhibitors. Part 1: Amides and ureas

Crescenzi, B, Poma, M, Ontoria, JM, Marchetti, A, Nizi, E, Matassa, VG, and Gardelli, C

LETTERS IN DRUG DESIGN & DISCOVERY 2005. 2(6): 451-455, 5


34. 48538 OI-LS-342; WOS-OI-2/19/2006

Phenyldihydroxypyrimidines as HCVNS5B RNA dependent RNA polymerase inhibitors. Part II: Sulfonamides

Ponzi, S, Giuliano, C, Donghi, M, Poma, M, Matassa, VG, and Stansfield, I

LETTERS IN DRUG DESIGN & DISCOVERY 2005. 2(6): 456-461, 6


35. 48539 OI-LS-342; WOS-OI-2/19/2006

Inhibitors of hepatitis C virus NS3 center dot 4A protease: P-2 proline variants

Farmer, LJ, Britt, SD, Cottrell, KM, Court, JJ, Courtney, LF, Deininger, DD, Gates, CA, Harbeson, SL, Lin, K, Lin, C, Luong, YP, Maxwell, JP, Pitlik, J, Rao, BG, Schairer, WC, Thomson, JA, Tung, RD, Van, Drie JH, Wei, YY, and Perni, RB

LETTERS IN DRUG DESIGN & DISCOVERY 2005. 2(7): 497-502, 6


36. 48540 OI-LS-342; WOS-OI-2/19/2006

Synthesis and anti-mycobacterial activity of N '-[(E)-(disubstituted-phenyl)methylidene]isoni otino-hydrazide derivatives

Junior, IN, Lourenco, MCS, das Gracas, M, Henriques, MO, Ferreira, B, Vasconcelos, TRA, Peralta, MA, de Oliveira, PSM, Wardell, SMSV, and de Souza, MVN

LETTERS IN DRUG DESIGN & DISCOVERY 2005. 2(7): 563-566, 4


37. 48541 OI-LS-342; WOS-OI-2/19/2006

A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase

Paeshuyse, J, Leyssen, P, Mabery, E, Boddeker, N, Vrancken, R, Froeyen, M, Ansari, IH, Dutartre, H, Rozenski, J, Gil, LHVG, Letellier, C, Lanford, R, Canard, B, Koenen, F, Kerkhofs, P, Donis, RO, Herdewijn, P, Watson, J, De, Clercq E, Puerstinger, G, and Neyts, J

JOURNAL OF VIROLOGY 2006. 80(1): 149-160, 12


38. 48542 OI-LS-342; WOS-OI-2/19/2006

Hurghadolide A and swinholide I, potent actin-microfilament disrupters from the Red Sea sponge Theonella swinhoei

Youssef, DTA and Mooberry, SL

JOURNAL OF NATURAL PRODUCTS 2006. 69(1): 154-157, 4


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