ONLINE DATABASE SEARCH - OI-LS-344 MEMO
1. 48623 OI-LS-344; PUBMED-OI-3/20/2006
A Mechanism of Virulence: Virulent Mycobacterium tuberculosis Strain H37Rv, but Not Attenuated H37Ra, Causes Significant Mitochondrial Inner Membrane Disruption in Macrophages Leading to Necrosis
Chen, M, Gan, H, and Remold, HG
J Immunol 2006. 176(6): 3707-3716
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16517739&dopt=abstract
2. 48624 OI-LS-344; PUBMED-OI-3/20/2006
Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease
Perni, RB, Almquist, SJ, Byrn, RA, Chandorkar, G, Chaturvedi, PR, Courtney, LF, Decker, CJ, Dinehart, K, Gates, CA, Harbeson, SL, Heiser, A, Kalkeri, G, Kolaczkowski, E, Lin, K, Luong, YP, Rao, BG, Taylor, WP, Thomson, JA, Tung, RD, Wei, Y, Kwong, AD, and Lin, C
Antimicrob Agents Chemother 2006. 50(3): 899-909
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16495249&dopt=abstract
3. 48625 OI-LS-344; PUBMED-OI-3/20/2006
Synthesis and Antiviral Evaluation of Alkoxyalkyl Derivatives of 9-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)adenine against Cytomegalovirus and Orthopoxviruses
Beadle, JR, Wan, WB, Ciesla, SL, Keith, KA, Hartline, C, Kern, ER, and Hostetler, KY
J Med Chem 2006. 49(6): 2010-5
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16539388&dopt=abstract
4. 48626 OI-LS-344; EMBASE-OI-3/20/2006
Structure-activity relationship for nucleoside analogs as inhibitors and substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety
Long, Mary C and Parker, William B
Biochemical Pharmacology 2006. In Press, Accepted Manuscript
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T4P-4JFH6SW-3/2/822219f9a7c508206209c160b5286c06
5. 48627 OI-LS-344; EMBASE-OI-3/20/2006
Antiviral and antituberculous activity of Helichrysum melanacme constituents
Lall, N, Hussein, AA, and Meyer, JJM
Fitoterapia 2006. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6VSC-4JF97B2-1/2/de53525aafbb02316a052d4fbf3f89f9
6. 48628 OI-LS-344; PUBMED-OI-3/20/2006
Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-[3-(1-adamantyl)-4-substituted-5-thioxo-1,2,4-triazolin-1-yl] acetic acids, 2-[3-(1-adamantyl)-4-substituted-5-thioxo-1,2,4-triazolin-1-yl]propionic acids and related derivatives
Al-Deeb, OA, Al-Omar, MA, El-Brollosy, NR, Habib, EE, Ibrahim, TM, and El-Emam, AA
Arzneimittelforschung 2006. 56(1): 40-47
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16478004&dopt=abstract
7. 48629 OI-LS-344; PUBMED-OI-3/20/2006
Present status and future prospects of chemotherapeutics for intractable infections due to Mycobacterium avium complex
Tomioka, H
Curr Drug Discov Technol 2004. 1(4): 255-68
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16472242&dopt=abstract
8. 48630 OI-LS-344; EMBASE-OI-3/20/2006
Pyranocoumarin, a novel anti-TB pharmacophore: Synthesis and biological evaluation against Mycobacterium tuberculosis
Xu, Ze-Qi, Pupek, Krzysztof, Suling, William J, Enache, Livia, and Flavin, Michael T
Bioorganic & Medicinal Chemistry 2006. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF8-4JCSK0M-2/2/86fbdefe94dcdb1e7253fea5416b270c
9. 48631 OI-LS-344; PUBMED-OI-3/20/2006
Influenza pandemics: past, present and future
Hsieh, YC, Wu, TZ, Liu, DP, Shao, PL, Chang, LY, Lu, CY, Lee, CY, Huang, FY, and Huang, LM
J Formos Med Assoc 2006. 105(1): 1-6
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16440064&dopt=abstract
10. 48632 OI-LS-344; PUBMED-OI-3/20/2006
Viral hepatitis treatment and beyond: a review of CROI 2005
Wilson, L and Gebo, K
Hopkins HIV Rep 2005. 17(3): 10-1, 16
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16419312&dopt=abstract
11. 48633 OI-LS-344; EMBASE-OI-3/20/2006
Ethnopharmacological evaluation of the informant consensus model on anti-tuberculosis claims among the Manus
Case, Ryan J, Franzblau, Scott G, Wang, Yuehong, Cho, Sang Hyun, Soejarto, DDoel, and Pauli, Guido F
Journal of Ethnopharmacology 2006. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T8D-4J2TSK8-2/2/fbbf2c6729ee7280bf41ea0001823d0a
12. 48634 OI-LS-344; EMBASE-OI-3/20/2006
Novel Inhibitors of Hepatitis C Virus RNA-dependent RNA Polymerases
Lee, Gary, Piper, Derek E, Wang, Zhulun, Anzola, John, Powers, Jay, Walker, Nigel, and Li, Yang
Journal of Molecular Biology 2006. 357(4): 1051-1057
HYPERLINK:
http://www.sciencedirect.com/science/article/B6WK7-4J554RY-2/2/affee7a6de984abb455f78ee2f1d17d6
13. 48635 OI-LS-344; WOS-OI-3/12/2006
Synthesis and antimicrobial evaluation of some 4-or 6-chloroisatin derivatives
Pandeya, SN, Raja, AS, and Nath, G
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY 2006. 45 (2): 494-499, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235555800011
14. 48636 OI-LS-344; WOS-OI-3/12/2006
The robe of antiviral agents in the management of viral hepatitis
Mutimer, D
CLINICAL MEDICINE 2006. 6(1): 29-34, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235642500008
15. 48637 OI-LS-344; WOS-OI-3/12/2006
Schiff base conjugates of p-aminosalicylic acid as antimycobacterial agents
Patole, J, Shingnapurkar, D, Padhye, S, and Ratledge, C
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2006. 16(6): 1514-1517, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235492800012
16. 48638 OI-LS-344; WOS-OI-3/12/2006
Depeptidization efforts on P-3-P '(2) alpha-ketoamide inhibitors of HCVNS3-4A serine protease: Effect on HCV replicon activity
Bogen, SL, Ruan, S, Liu, R, Agrawal, S, Pichardo, J, Prongay, A, Baroudy, B, Saksena, AK, Girijavallabhan, V, and Njoroge, FG
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2006. 16(6): 1621-1627, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235492800034
17. 48639 OI-LS-344; WOS-OI-3/12/2006
Crystal structure of the pantothenate synthetase from Mycobacterium tuberculosis snapshots of the enzyme in action
Wang, SS and Eisenberg, D
BIOCHEMISTRY 2006. 45(6): 1554-1561, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235631400003
18. 48640 OI-LS-344; WOS-OI-3/12/2006
Genomics applied to drug candidate prioritization and for identification of novel therapeutically useful properties of existing drugs
Jarnagin, K, Roter, A, Tolley, A, Lee, M, and Natsoulis, CG
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005. 229: U156-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235066600269
19. 48641 OI-LS-344; WOS-OI-3/12/2006
Development of new tuberculosis drug candidates
Laughon, BE
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005. 229: U164-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235066600310
20. 48642 OI-LS-344; WOS-OI-3/12/2006
Novel inhibitors of InhA, the enoyl reductase from mycobacterium tuberculosis
Tonge, PJ, Sullivan, TJ, Novichenok, P, Truglio, JJ, Kisker, C, Johnson, F, and Slayden, RA
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005. 229: U164-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235066600314
21. 48643 OI-LS-344; WOS-OI-3/12/2006
Cell wall of mycobacterium tuberculosis and drug discovery
Brennan, PJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005. 229: U164-U165, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235066600315
22. 48644 OI-LS-344; WOS-OI-3/12/2006
Synthesis and design of 2,4-diamino-6-substituted-pyrido[3,2-D]pyrimidines as dihydrofolate reductase inhibitors from opportunistic pathogens
Gangjee, A, Ye, ZQ, Kisliuk, RL, and Queener, SF
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005. 229: U172-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235066600352
23. 48645 OI-LS-344; WOS-OI-3/12/2006
Developing novel inhibitors of the enoyl reductase from mycobacterium tuberculosis (INHA) : SAR studies of triclosan congeners
Sullivan, TJ, Novichenok, P, Truglio, JJ, Kisker, C, Johnson, F, Slayden, RA, and Tonge, PJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005. 229: U176-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235066600376
24. 48646 OI-LS-344; WOS-OI-3/19/2006
Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis
Frenois, F, Baulard, AR, and Villeret, V
TUBERCULOSIS 2006. 86(2): 110-114, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235740800002
25. 48647 OI-LS-344; WOS-OI-3/19/2006
Development of a toxicogenomics in vitro assay for the efficient characterization of compounds
Yang, Y, Abel, SJ, Ciurlionis, R, and Waring, JF
PHARMACOGENOMICS 2006. 7(2): 177-186, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235752500010
26. 48648 OI-LS-344; WOS-OI-3/19/2006
Academia given a helping hand in drug development
Branca, MA
NATURE REVIEWS DRUG DISCOVERY 2006. 5(3): 177-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235836300003
27. 48649 OI-LS-344; WOS-OI-3/19/2006
Computer-assisted analysis of the interactions of macrocyclic inhibitors with wild type and mutant D168A hepatitis C virus NS3 serine protease
da Cunha, EFF, Ramalho, TC, Taft, CA, and de Alencastro, RB
LETTERS IN DRUG DESIGN & DISCOVERY 2006. 3(1): 17-28, 12
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235724000004
28. 48650 OI-LS-344; WOS-OI-3/19/2006
On the horizon: Promising investigational antiretroviral agents
McNicholl, IR and McNicholl, JJ
CURRENT PHARMACEUTICAL DESIGN 2006. 12(9): 1091-1103, 13
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235758400007
29. 48651 OI-LS-344; WOS-OI-3/19/2006
New methods for medicinal chemistry - Universal gene cloning and expression systems for production of marine bioactive metabolites
Dunlap, WC, Jaspars, M, Hranueli, D, Battershill, CN, Peric-Concha, N, Zucko, J, Wright, SH, and Long, PF
CURRENT MEDICINAL CHEMISTRY 2006. 13(6): 697-710, 14
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235756900008
30. 48652 OI-LS-344; WOS-OI-3/19/2006
Effectiveness of fluoroquinolones against Mycobacterium abscessus in vivo
Caballero, AR, Marquart, ME, O'Callaghan, RJ, Thibodeaux, BA, Johnston, KH, and Dajcs, JJ
CURRENT EYE RESEARCH 2006. 31(1): 23-29, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000234819700003
31. 48653 OI-LS-344; WOS-OI-3/19/2006
rmlB and rmlC genes are essential fair growth with mycobacteria
Li, W, Xin, Y, McNeil, MR, and Ma, YF
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2006. 342(1): 170-178, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235793800023
32. 48654 OI-LS-344; WOS-OI-3/19/2006
SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells
Malcolm, BA, Liu, R, Lahser, F, Agrawal, S, Belanger, B, Butkiewicz, N, Chase, R, Gheyas, F, Hart, A, Hesk, D, Ingravallo, P, Jiang, C, Kong, R, Lu, J, Pichardo, J, Prongay, A, Skelton, A, Tong, X, Venkatraman, S, Xia, E, Girijavallabhan, V, and Njoroge, FG
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2006. 50(3): 1013-1020, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235786300026
33. 48655 OI-LS-344; WOS-OI-3/19/2006
Molecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhA
Leung, ETY, Ho, PL, Yuen, KY, Woo, WL, Lam, TH, Kao, RY, Seto, WH, and Yam, WC
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2006. 50(3): 1075-1078, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235786300034