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1. 48940 OI-LS-349; PUBMED-OI-5/30/2006

Antimicrosporidial Activities of Fumagillin, TNP-470, Ovalicin, and Ovalicin Derivatives In Vitro and In Vivo

Didier, PJ, Phillips, JN, Kuebler, DJ, Nasr, M, Brindley, PJ, Stovall, ME, Bowers, LC, and Didier, ES

Antimicrob Agents Chemother 2006. 50(6): 2146-55


2. 48941 OI-LS-349; PUBMED-OI-5/30/2006

Novel Conjugate of Moxifloxacin and Carboxymethylated Glucan with Enhanced Activity against Mycobacterium tuberculosis

Schwartz, YS, Dushkin, MI, Vavilin, VA, Melnikova, EV, Khoschenko, OM, Kozlov, VA, Agafonov, AP, Alekseev, AY, Rassadkin, Y, Shestapalov, AM, Azaev, MS, Saraev, DV, Filimonov, PN, Kurunov, Y, Svistelnik, AV, Krasnov, VA, Pathak, A, Derrick, SC, Reynolds, RC, Morris, S, and Blinov, VM

Antimicrob Agents Chemother 2006. 50(6): 1982-8


3. 48942 OI-LS-349; PUBMED-OI-5/30/2006

Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site

Gopalsamy, A, Chopra, R, Lim, K, Ciszewski, G, Shi, M, Curran, KJ, Sukits, SF, Svenson, K, Bard, J, Ellingboe, JW, Agarwal, A, Krishnamurthy, G, Howe, AY, Orlowski, M, Feld, B, O'connell, J, and Mansour, TS

J Med Chem 2006. 49(11): 3052-5


4. 48943 OI-LS-349; PUBMED-OI-5/30/2006

Identification of New Diamine Scaffolds with Activity against Mycobacterium tuberculosis

Bogatcheva, E, Hanrahan, C, Nikonenko, B, Samala, R, Chen, P, Gearhart, J, Barbosa, F, Einck, L, Nacy, CA, and Protopopova, M

J Med Chem 2006. 49(11): 3045-8


5. 48944 OI-LS-349; PUBMED-OI-5/30/2006

Small molecule and biologic modulators of the immune response to hepatitis C virus

Mbow, ML, Eaton-Bassiri, A, Glass, WG, Del, Vecchio AM, and Sarisky, RT

Mini Rev Med Chem 2006. 6(5): 527-31


6. 48945 OI-LS-349; PUBMED-OI-5/30/2006

Susceptibility of Mycobacterium tuberculosis Strains to Gatifloxacin and Moxifloxacin by Different Methods

Somasundaram, S and Paramasivan, NC

Chemotherapy 2006. 52(4): 190-195


7. 48946 OI-LS-349; PUBMED-OI-5/30/2006

Brevinin-1BYa: a naturally occurring peptide from frog skin with broad-spectrum antibacterial and antifungal properties

Pal, T, Abraham, B, Sonnevend, A, Jumaa, P, and Conlon, JM

Int J Antimicrob Agents 2006. 27(6): 525-529


8. 48947 OI-LS-349; SCIFINDER-OI-5/22/2006

MyD88-dependent pathways mediate resistance to Cryptosporidium parvum infection in mice

Rogers, KA, Rogers, AB, Leav, BA, Sanchez, A, Vannier, E, Uematsu, S, Akira, S, Golenbock, D, and Ward, HD

Infection and Immunity 2006. 74(1): 549-556

9. 48948 OI-LS-349; SCIFINDER-OI-5/22/2006

Interaction of Cryptosporidium hominis and Cryptosporidium parvum with primary human and bovine intestinal cells

Hashim, Amna, Mulcahy, Grace, Bourke, Billy, and Clyne, Marguerite

Infection and Immunity 2006. 74(1): 99-107

10. 48949 OI-LS-349; PUBMED-OI-5/30/2006

Antifungal and antimycobacterial activity of new imidazole and triazole derivatives. A combined experimental and computational approach

Banfi, E, Scialino, G, Zampieri, D, Mamolo, MG, Vio, L, Ferrone, M, Fermeglia, M, Paneni, MS, and Pricl, S

J Antimicrob Chemother 2006.


11. 48950 OI-LS-349; SCIFINDER-OI-5/22/2006

Antibodies enhance the protective effect of CD4 + T lymphocytes in SCID mice perorally infected with Encephalitozoon cuniculi

Sak, B, Salat, J, Horka, H, Sakova, K, and Ditrich, O

Parasite Immunology 2006. 28(3): 95-99

12. 48951 OI-LS-349; PUBMED-OI-5/30/2006

Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance

Shi, R, Azzi, A, Gilbert, C, Boivin, G, and Lin, SX

Proteins 2006.


13. 48952 OI-LS-349; SCIFINDER-OI-5/22/2006

Variability in infection efficiency in vitro of different strains of the microsporidian Encephalitozoon hellem

Haro Maria, Aguila Carmen, Fenoy Soledad, and Henriques-Gil Nuno

The Journal of eukaryotic microbiology 2006. 53(1): 46-8.

14. 48953 OI-LS-349; PUBMED-OI-5/30/2006

Antiproliferative activities of two novel quinuclidine inhibitors against Toxoplasma gondii tachyzoites in vitro

Martins-Duarte, ES, Urbina, JA, de, Souza W, and Vommaro, RC

J Antimicrob Chemother 2006.


15. 48954 OI-LS-349; PUBMED-OI-5/30/2006

Comparative effects of ertapenem, imipenem, and meropenem on the colonization of the gastrointestinal tract of mice by Candida albicans

Samonis, G, Maraki, S, Leventakos, K, Spanaki, AM, Kateifidis, A, Galanakis, E, Tselentis, Y, Falagas, ME, and Mantadakis, E

Med Mycol 2006. 44(3): 233-5


16. 48955 OI-LS-349; PUBMED-OI-5/30/2006

New plan for tuberculosis


S Afr Med J 2006. 96(4): 278, 280


17. 48956 OI-LS-349; SCIFINDER-OI-5/22/2006

Polymers with fungicidal activity

Schmidt, Oskar

PATENT: WO 2006047800 ISSUE DATE: 20060511

APPLICATION: 2005 PP: 15 pp.

ASSIGNEE: (Austria)

18. 48957 OI-LS-349; SCIFINDER-OI-5/22/2006

Antifungal properties of some arylsuloanylpyrazine-2-carboxylic acid derivatives

Jampilek, Josef, Dolezal, Martin, Palek, Lukas, Silva, Luis, and Buchta, Vladimir

Folia Pharmaceutica Universitatis Carolinae 2006. 33: 23-29

19. 48958 OI-LS-349; SCIFINDER-OI-5/22/2006

Antifungal activity of 1-phenyl-5-benzylsulfanyltetrazoles

Adamec, Jan, Waisser, Karel, Silva, Luis, and Buchta, Vladimir

Folia Pharmaceutica Universitatis Carolinae 2006. 33: 13-17

20. 48959 OI-LS-349; PUBMED-OI-5/30/2006

Leflunomide: a possible alternative for gangciclovir sensitive and resistant cytomegalovirus infections

Sudarsanam, TD, Sahni, RD, and John, GT

Postgrad Med J 2006. 82(967): 313-4


21. 48960 OI-LS-349; PUBMED-OI-5/30/2006

Moxifloxacin versus Ethambutol in the First Two Months of Treatment for Pulmonary Tuberculosis

Burman, WJ, Goldberg, S, Johnson, JL, Muzanye, G, Engle, M, Mosher, AW, Choudhri, S, Daley, CL, Munsiff, SS, Zhao, Z, Vernon, A, and Chaisson, RE

Am J Respir Crit Care Med 2006.


22. 48961 OI-LS-349; SCIFINDER-OI-5/22/2006

COX-1, COX-2 inhibitors and antifungal agents from Croton hutchinsonianus

Athikomkulchai, Sirivan, Prawat, Hunsa, Thasana, Nopporn, Ruangrungsi, Nijsiri, and Ruchirawat, Somsak

Chemical & Pharmaceutical Bulletin 2006. 54(2): 262-264

23. 48962 OI-LS-349; PUBMED-OI-5/30/2006

Cytomegalovirus disease in the era of highly active antiretroviral therapy (HAART)

Steininger, C, Puchhammer-Stockl, E, and Popow-Kraupp, T

J Clin Virol 2006.


24. 48963 OI-LS-349; PUBMED-OI-5/30/2006

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria

Wehenkel, A, Fernandez, P, Bellinzoni, M, Catherinot, V, Barilone, N, Labesse, G, Jackson, M, and Alzari, PM

FEBS Lett 2006. 580(13): 3018-22


25. 48964 OI-LS-349; SCIFINDER-OI-5/22/2006

Antifungal properties of new series of quinoline derivatives

Musiol, Robert, Jampilek, Josef, Buchta, Vladimir, Silva, Luis, Niedbala, Halina, Podeszwa, Barbara, Palka, Anna, Majerz-Maniecka, Katarzyna, Oleksyn, Barbara, and Polanski, Jaroslaw

Bioorganic & Medicinal Chemistry 2006. 14(10): 3592-3598

26. 48965 OI-LS-349; WOS-OI-5/21/2006

Antimycobacterial brominated metabolites from two species of marine sponges

De Oliveira, MF, de Oliveira, JHHL, Galetti, FCS, De Souza, AO, Silva, CL, Hajdu, E, Peixinho, S, and Berlinck, RGS

PLANTA MEDICA 2006. 72(5): 437-441, 5


27. 48966 OI-LS-349; SCIFINDER-OI-5/22/2006

Synthesis of 1-acyl-2-alkylthio-1,2,4-triazolobenzimidazoles with antifungal, anti-inflammatory and analgesic effects

Mohamed, Bahaa G, Abdel-Alim, Abdel-Alim M, and Hussein, Mostafa A

Acta Pharmaceutica (Zagreb, Croatia) 2006. 56(1): 31-48

28. 48967 OI-LS-349; SCIFINDER-OI-5/22/2006

N-Methyl-4-hydroxy-2-pyridinone analogues from Fusarium oxysporum

Jayasinghe, Lalith, Abbas, Hamed K, Jacob, Melissa R, Herath, Wimal HMW, and Nanayakkara, NPDhammika

Journal of Natural Products 2006. 69(3): 439-442

29. 48968 OI-LS-349; SCIFINDER-OI-5/22/2006

Antifungal bis[bibenzyls] from the chinese liverwort Marchantia polymorpha L

Niu, Chong, Qu, Jian-Bo, and Lou, Hong-Xiang

Chemistry & Biodiversity 2006. 3(1): 34-40

30. 48969 OI-LS-349; SCIFINDER-OI-5/22/2006

Synthesis and biological evaluation of some pyrazolinylpyridines and pyrazolylpyridines

Singh Tripti, Sharma Shalabh, Srivastava Virendra Kishore, and Kumar Ashok

Archiv der Pharmazie 2006. 339(1): 24-31.

31. 48970 OI-LS-349; SCIFINDER-OI-5/22/2006

Synthesis and antimicrobial evaluation of some t(3)-alkyl and t(3),t(5)-dimethyl-r(2),c(6)-di-2'- furfurylpiperidin-4-one and its derivatives

Jayabharathi, J, Sivakumar, R, and Praveena, A

Medicinal Chemistry Research 2006. 14(4): 198-210

32. 48971 OI-LS-349; WOS-OI-5/21/2006

Synthesis of 1-[3-(4-benz triazol-1/2- l-3-fluoro-p enyl)-2-oxo- xazolidin-5-ylmethyl]-3-substituted-thiourea derivatives as antituberculosis agents

Dixit, PP, Patil, VJ, Nair, PS, Jain, S, Sinha, N, and Arora, SK



33. 48972 OI-LS-349; WOS-OI-5/21/2006

Conserved fungal genes as potential targets for broad-spectrum antifungal drug discovery

Liu, MP, Healy, MD, Dougherty, BA, Esposito, KM, Maurice, TC, Mazzucco, CE, Bruccoleri, RE, Davison, DB, Frosco, M, Barrett, JF, and Wang, YK

EUKARYOTIC CELL 2006. 5(4): 638-649, 12


34. 48973 OI-LS-349; SCIFINDER-OI-5/22/2006

Oxazolidinone derivatives, particularly benzoxadiazole phenyloxazolidinones, useful as antimicrobials, and processes for their preparation, pharmaceutical compositions containing them, and methods of their use for treating microbial infections

Das Biswajit, Rudra, Sonali, Salman, Mohammad, and Rattan, Ashok

PATENT: WO 2006035283 ISSUE DATE: 20060406

APPLICATION: 2005 PP: 79 pp.

ASSIGNEE: (Ranbaxy Laboratories Limited, India

35. 48974 OI-LS-349; SCIFINDER-OI-5/22/2006

Crystallizing new approaches for antimicrobial drug discovery

Schmid, Molly B

Biochemical Pharmacology 2006. 71(7): 1048-1056

36. 48975 OI-LS-349; SCIFINDER-OI-5/22/2006

Rational Development of b-Peptide Inhibitors of Human Cytomegalovirus Entry

English, Emily Payne, Chumanov, Robert S, Gellman, Samuel H, and Compton, Teresa

Journal of Biological Chemistry 2006. 281(5): 2661-2667

37. 48976 OI-LS-349; SCIFINDER-OI-5/22/2006

Cyclic cidofovir (HPMPC) prevents congenital cytomegalovirus infection in a guinea pig model

Schleiss, Mark R, Anderson, Jodi L, and McGregor, Alistair

Virology Journal 2006. 3: No pp. given

38. 48977 OI-LS-349; SCIFINDER-OI-5/22/2006

Inhibition of ganciclovir-resistant human cytomegalovirus replication by Kampo (Japanese herbal medicine)

Murayama, Tsugiya, Yamaguchi, Nobuo, Iwamoto, Kozo, and Eizuru, Yoshito

Antiviral Chemistry & Chemotherapy 2006. 17(1): 11-16

39. 48978 OI-LS-349; SCIFINDER-OI-5/22/2006

Substituted 5-carboxyamide pyrazoles and [1,2,4]triazoles as antiviral agents

Shipps, Gerald W Jr, Curran, Patrick J, Annis, DAllen, Nash, Huw M, Cooper, Alan B, Zhu, Hugh Y, Wang, James J-S, Desai, Jagdish A, and Girijavallabhan, Viyyoor Moopil

PATENT: WO 2006050034 ISSUE DATE: 20060511

APPLICATION: 2005 PP: 104 pp.

ASSIGNEE: (Schering Corporation, USA

40. 48979 OI-LS-349; SCIFINDER-OI-5/22/2006

Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents

Shipps, Gerald W Jr, Wang, Tong, Rosner, Kristen E, Curran, Patrick J, Cooper, Alan B, and Girijavallabhan, Viyyoor Moopil

PATENT: WO 2006050035 ISSUE DATE: 20060511

APPLICATION: 2005 PP: 80 pp.

ASSIGNEE: (Schering Corporation, USA

41. 48980 OI-LS-349; SCIFINDER-OI-5/22/2006

Nucleoside analog inhibitors of hepatitis C virus replication

Carroll, SS and Olsen, DB

Infectious Disorders: Drug Targets 2006. 6(1): 17-29

42. 48981 OI-LS-349; SCIFINDER-OI-5/22/2006

Preparation of tetracyclic indole derivatives as antiviral agents

Conte, Immacolata, Ercolani, Caterina, Narjes, Frank, Pompei, Marco, Rowley, Michael, and Stansfield, Ian

PATENT: WO 2006046030 ISSUE DATE: 20060504

APPLICATION: 2005 PP: 79 pp.

ASSIGNEE: (Istituto di Ricerche di Biologia Molecolare p Angeletti SpA, Italy

43. 48982 OI-LS-349; SCIFINDER-OI-5/22/2006

Preparation of 4-(methoxycarbonyl)pyrrolidine-2-carboxylic acid derivatives as hepatitis C virus inhibitors

Guidetti, Rossella, Haigh, David, Hartley, Charles David, Howes, Peter David, Nerozzi, Fabrizio, and Smith, Stephen Allan

PATENT: WO 2006045613 ISSUE DATE: 20060504

APPLICATION: 2005 PP: 58 pp.

ASSIGNEE: (Glaxo Group Ltd., UK

44. 48983 OI-LS-349; SCIFINDER-OI-5/22/2006

Preparation of 4-(pyrazin-2-yl)pyrrolidine-2-carboxylic acid derivatives as hepatitis C virus inhibitors

Guidetti, Rossella, Haigh, David, Hartley, Charles David, Howes, Peter David, Nerozzi, Fabrizio, and Smith, Stephen Allan

PATENT: WO 2006045615 ISSUE DATE: 20060504

APPLICATION: 2005 PP: 55 pp.

ASSIGNEE: (Glaxo Group Limited, UK

45. 48984 OI-LS-349; SCIFINDER-OI-5/22/2006

Inhibition of hepatitis C virus NS3-NS4A protease activity with VX-950

Lin, Chao and Taylor, William P

PATENT: WO 2006039488 ISSUE DATE: 20060413

APPLICATION: 2005 PP: 57 pp.

ASSIGNEE: (Vertex Pharmaceuticals Incorporated, USA

46. 48985 OI-LS-349; SCIFINDER-OI-5/22/2006

Preparation of 4-hydroxy-3-heterocyclylalkyl-5,6-dihydro-2H-pyran-2-ones as inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same

Gonzalez, Javier, Jewell, Tanya Michelle, Li, Hui, Linton, Angelica, and Tatlock, John Howard

PATENT: WO 2006018725 ISSUE DATE: 20060223

APPLICATION: 2005 PP: 315 pp.

ASSIGNEE: (Pfizer Inc., USA

47. 48986 OI-LS-349; WOS-OI-5/28/2006

Fighting viral hepatitis with small RNAS

Will, H and Grundhoff, A

JOURNAL OF HEPATOLOGY 2006. 44(5): 1009-1011, 3


48. 48987 OI-LS-349; WOS-OI-5/28/2006

Synthesis of 3-cyanoflavones and their biological evaluation

Lassagne, F, Bombarda, I, Dherbomez, M, Sinbandhit, S, and Gaydou, EM

HETEROCYCLES 2006. 68(4): 787-799, 13


49. 48988 OI-LS-349; WOS-OI-5/28/2006

The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus

Dixit, NM and Perelson, AS



50. 48989 OI-LS-349; WOS-OI-5/28/2006

DBMODELING - A database applied to the study of protein targets from genome projects

da Silveira, NJF, Bonalumi, CE, Uchao, HB, Pereira, JH, Canduri, F, and de Azevedo, WF



51. 48990 OI-LS-349; WOS-OI-5/28/2006

Molecular models of tryptophan synthase from Mycobacterium tuberculosis complexed with inhibitors

Dias, MVB, Canduri, F, da Silveira, NJF, Czekster, CM, Basso, LA, Palma, MS, Santos, DS, and de Azevedo, WF



52. 48991 OI-LS-349; WOS-OI-5/28/2006

Antifungal activity of C-27 steroidal saponins

Yang, CR, Zhang, Y, Jacob, MR, Khan, SI, Zhang, YJ, and Li, XC



53. 48992 OI-LS-349; WOS-OI-5/28/2006

Significance of mutations in embB codon 306 for prediction of ethambutol resistance in clinical Mycobactetium tuberculosis isolates

Plinke, C, Rusch-Gerdes, S, and Niemann, S



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