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1. 49067 OI-LS-351; SCIFINDER-OI-6/20/2006

Comparison of a conventional antimicrobial susceptibility assay to an oligonucleotide chip system for detection of drug resistance in Mycobacterium tuberculosis isolates

Park, Heekyung, Song, Eun Ju, Song, Eun Sil, Lee, Eun Yup, Kim, Cheol Min, Jeong, Seok Hoon, Shin, Jeong Hwan, Jeong, Joseph, Kim, Sunjoo, Park, Young Kil, Bai, Gill-Han, and Chang, Chulhun L

Journal of Clinical Microbiology 2006. 44(5): 1619-1624

2. 49068 OI-LS-351; SCIFINDER-OI-6/20/2006

Oxazolidinone derivatives as antimicrobials, and their preparation, pharmaceutical composition and use for treatment of microbial infections

Das, Biswajit, Yadav, Ajay Singh, Ahmed, Shahadat, Gujrati, Arti, Ghosh, Soma, and Rattan, Ashok

PATENT: WO 2006051408 ISSUE DATE: 20060518

APPLICATION: 2005 PP: 59 pp.

ASSIGNEE: (Ranbaxy Laboratories Limited, India

3. 49069 OI-LS-351; PUBMED-OI-6/26/2006

Targets and Tools: Recent Advances in the Development of Anti-HCV Nucleic Acids

Romero-Lopez, C, Sanchez-Luque, FJ, and Berzal-Herranz, A

Infect Disord Drug Targets 2006. 6(2): 121-45


4. 49070 OI-LS-351; PUBMED-OI-6/26/2006

Antimicrobial activity studies on some piperidine and pyrrolidine substituted halogenobenzene derivatives

Arslan, S, Logoglu, E, and Oktemer, A

J Enzyme Inhib Med Chem 2006. 21(2): 211-4


5. 49071 OI-LS-351; PUBMED-OI-6/26/2006

Allosteric inhibition of the hepatitis C virus NS5B RNA dependent RNA polymerase

Koch, U and Narjes, F

Infect Disord Drug Targets 2006. 6(1): 31-41


6. 49072 OI-LS-351; PUBMED-OI-6/26/2006

Synthesis and evaluation of phenoxy acetic acid derivatives as anti-mycobacterial agents

Yar, MS, Siddiqui, AA, and Ali, MA

Bioorg Med Chem Lett 2006.


7. 49073 OI-LS-351; PUBMED-OI-6/26/2006

Synthesis, antibacterial and antitubercular activities of some 7-+AFs-4-(5-amino-+AFs-1,3,4+AF0-thiadiazole-2-sulfonyl)-piperazin-1-yl+AF0- fluoroquinolonic derivatives

Talath, S and Gadad, AK

Eur J Med Chem 2006.


8. 49074 OI-LS-351; PUBMED-OI-6/26/2006

Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis

Johnson, JL, Hadad, DJ, Boom, WH, Daley, CL, Peloquin, CA, Eisenach, KD, Jankus, DD, Debanne, SM, Charlebois, ED, Maciel, E, Palaci, M, and Dietze, R

Int J Tuberc Lung Dis 2006. 10(6): 605-12


9. 49075 OI-LS-351; PUBMED-OI-6/26/2006

In vitro activity of linezolid against Mycobacterium tuberculosis complex, including multidrug-resistant Mycobacterium bovis isolates

Tato, M, de, la Pedrosa EG, Canton, R, Gomez-Garcia, I, Fortun, J, Martin-Davila, P, Baquero, F, and Gomez-Mampaso, E

Int J Antimicrob Agents 2006.


10. 49076 OI-LS-351; SCIFINDER-OI-6/20/2006

Synthesis and antimycobacterial activities of certain trifluoromethyl-aminoquinoline derivatives

Mital, Alka, Negi, Villendra Singh, and Ramachandran, Uma

ARKIVOC (Gainesville, FL, United States) 2006.(10): 220-227

11. 49077 OI-LS-351; PUBMED-OI-6/26/2006

Characterization of the phosphorylation sites of Mycobacterium tuberculosis serine/threonine protein kinases, PknA, PknD, PknE, and PknH by mass spectrometry

Molle, V, Zanella-Cleon, I, Robin, JP, Mallejac, S, Cozzone, AJ, and Becchi, M

Proteomics 2006.


12. 49078 OI-LS-351; PUBMED-OI-6/26/2006

Identification of cell cycle regulators in Mycobacterium tuberculosis by inhibition of septum formation and global transcriptional analysis

Slayden, RA, Knudson, DL, and Belisle, JT

Microbiology 2006. 152(Pt 6): 1789-97


13. 49079 OI-LS-351; PUBMED-OI-6/26/2006

Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus

Le Pogam, S, Kang, H, Harris, SF, Leveque, V, Giannetti, AM, Ali, S, Jiang, WR, Rajyaguru, S, Tavares, G, Oshiro, C, Hendricks, T, Klumpp, K, Symons, J, Browner, MF, Cammack, N, and Najera, I

J Virol 2006 . 80(12): 6146-6154


14. 49080 OI-LS-351; WOS-OI-6/26/2006

EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis

Sharma, K, Gupta, M, Krupa, A, Srinivasan, N, and Singh, Y

FEBS JOURNAL: FEBS J 2006. 273(12): 2711-2721, 11


15. 49081 OI-LS-351; WOS-OI-6/26/2006

Toxoplasma gondii: In vitro and in vivo activities of the hydroxynaphthoquinone 2-hydroxy-3-(1 '-propen-3-phenyl)-1, 4-naphthoquinone alone or combined with sulfadiazine

Ferreira, RA, Oliveira, AB, Ribeiro, MFB, Tafuri, WL, and Vitor, RWA

EXPERIMENTAL PARASITOLOGY: Exp. Parasitol 2006. 113(2): 125-129, 5


16. 49082 OI-LS-351; WOS-OI-6/26/2006

Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis I. Modifications to the adenine moiety

Long, MC and Parker, WB

BIOCHEMICAL PHARMACOLOGY: Biochem. Pharmacol 2006. 71(12): 1671-1682, 12


17. 49083 OI-LS-351; SCIFINDER-OI-6/20/2006

Bisbenzamidines for the treatment of Pneumocystis pneumonia or other infection

Walzer, Peter D, Cushion, Melanie T, Mayence, Annie, Huang, Tien Liang, and Vanden Eynde, Jean Jacques

PATENT: WO 2006021833 ISSUE DATE: 20060302

APPLICATION: 2004 PP: 68 pp.

ASSIGNEE: (University of Cincinnati, USA

18. 49084 OI-LS-351; SCIFINDER-OI-6/20/2006

Nonclassical 5-Alkyl-6-substituted arylthio-pyrrolo[2,3-d]pyrimidines as potent and selective Toxoplasma gondii dihydrofolate reductase inhibitors

Gangjee, Aleem, Jain, Hiteshkumar D, Kisliuk, Roy L, and Queener, Sherry F

Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006 2006.: MEDI-348

19. 49085 OI-LS-351; SCIFINDER-OI-6/20/2006

The effect of lectins on Cryptosporidium parvum oocyst in vitro attachment to host cells

Stein, Barry, Stover, Larry, Gillem, Ashley, Winters, Katherine, Lee, John H, and Chauret, Christian

Journal of Parasitology 2006. 92(1): 1-9

20. 49086 OI-LS-351; WOS-OI-6/26/2006

NIM811: An HCV replication inhibitor of novel mechanism, exhibits potent antiviral activities alone or in combination with a non-nucleoside HCV polymerase inhibitor

Boerner, JE, Ma, S, Yip, CLT, Cooreman, MP, Compton, T, and Lin, K

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A34-A35, 2


21. 49087 OI-LS-351; WOS-OI-6/26/2006

R1479 is a highly selective inhibitor of NS5B-dependent HCV replication and does not inhibit human DNA and RNA polymerases

Ma, H, Le Pogam, S, Leveque, V, Li, WX, Jiang, WR, Najera, I, Symons, J, Cammack, N, and Klumpp, K

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A35-1


22. 49088 OI-LS-351; WOS-OI-6/26/2006

Design and synthesis of novel anthranilic acid analogs as HCV polymerase inhibitors

Curran, K, Nittoli, T, Insaf, S, Prashad, A, Floyd, B, Orlowski, M, Howe, A, Chropra, R, Agrawal, A, and Bloom, J

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A53-1


23. 49089 OI-LS-351; WOS-OI-6/26/2006

Synthesis and evaluation of novel potential HCV helicase inhibitors

Brancale, A, Vlachakis, D, Barbera, MC, Silvestri, R, Berry, C, and Neyts, J

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A53-A54, 2


24. 49090 OI-LS-351; WOS-OI-6/26/2006

Identification of novel HCV inhibitors utilizing virtual screening

Cameron, DR

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A54-1


25. 49091 OI-LS-351; SCIFINDER-OI-6/20/2006

The design of hepatitis C protease inhibitors and the discovery of VX-950

Perni, RB

Abstracts, 37th Great Lakes Regional Meeting of the American Chemical Society 2006. 37: GLRM-028

26. 49092 OI-LS-351; WOS-OI-6/26/2006

HCVNS5B normucleoside inhibitors specifically block synthesis of single-stranded viral RNA catalyzed by HCV replication complexes in vitro

Yang, WG, Sun, YN, Phadke, A, Deshpande, M, and Huang, MJ

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A54-A55, 2


27. 49093 OI-LS-351; WOS-OI-6/26/2006

Potent inhibition of both HIV and HCV in vitro by a ring-expanded ("fat") nucleoside: Part II. Mechanistic studies of anti-HCV activity

Zhang, N, Zhang, P, Korba, B, Oldach, D, Lagrange, S, Cova, L, Baier, A, Borowski, P, Fattom, A, Winston, S, Fahim, R, and Hosmane, RS

ANTIVIRAL RESEARCH: Antiviral Res 2006. 70(1): A55-1


28. 49094 OI-LS-351; SCIFINDER-OI-6/20/2006

Preparation of nucleoside analogs for treating Hepatitis C and other Flaviviridae family viral infections

Keicher, Jesse D, Roberts, Christopher D, and Dyatkina, Natalia B

PATENT: US 2006111311 ISSUE DATE: 20060525

APPLICATION: 2005-18840 PP: 23 pp.

ASSIGNEE: (Genelabs Technologies, Inc. USA

29. 49095 OI-LS-351; SCIFINDER-OI-6/20/2006

Inhibition of hepatitis C replicon RNA synthesis by b-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication

Stuyver, Lieven J, McBrayer, Tamara R, Tharnish, Phillip M, Clark, Jeremy, Hollecker, Laurent, Lostia, Stefania, Nachman, Tammy, Grier, Jason, Bennett, Matthew A, Xie, Meng-Yu, Schinazi, Raymond F, Morrey, John D, Julander, Justin L, Furman, Phillip A, and Otto, Michael J

Antiviral Chemistry & Chemotherapy 2006. 17(2): 79-87

30. 49096 OI-LS-351; WOS-OI-6/18/2006

Inhibition of viruses by RNA interference

Stram, Y and Kuzntzova, L

VIRUS GENES 2006. 32(3): 299-306, 8


31. 49097 OI-LS-351; WOS-OI-6/18/2006

The effect of the administration of human gamma globulins in a model of BCG infection in mice

Olivares, N, Leon, A, Lopez, Y, Puig, A, Cadiz, A, Falero, G, Martinez, M, Sarmiento, ME, Farinas, M, Infante, JF, Sierra, G, Solis, RL, and Acosta, A

TUBERCULOSIS 2006. 86(3-4): 268-272, 5


32. 49098 OI-LS-351; SCIFINDER-OI-6/20/2006

Preparation of pyrazoles and [1,2,4]triazoles as antiviral agents

Shipps, Gerald W Jr, Curran, Patrick J, Annis, DAllen, Nash, Huw M, Cooper, Alan B, Zhu, Hugh Y, Wang, James J-S, Desai, Jagdish A, and Girijavallabhan, Viyyoor Moopil

PATENT: WO 2006050034 ISSUE DATE: 20060511

APPLICATION: 2005 PP: 104 pp.

ASSIGNEE: (Schering Corporation, USA

33. 49099 OI-LS-351; SCIFINDER-OI-6/20/2006

Discovery and development of VX-950, a novel, covalent, and reversible inhibitor of hepatitis C virus NS3.bul.4A serine protease

Lin, C, Kwong, AD, and Perni, RB

Infectious Disorders: Drug Targets 2006. 6(1): 3-16

34. 49100 OI-LS-351; SCIFINDER-OI-6/20/2006

Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine

Ruiz, Jacqueline C, Aldern, Kathy A, Beadle, James R, Hartline, Caroll B, Kern, Earl R, and Hostetler, Karl Y

Antiviral Chemistry & Chemotherapy 2006. 17(2): 89-95

35. 49101 OI-LS-351; SCIFINDER-OI-6/20/2006

Use of diindolylmethane-related indoles and growth factor receptor inhibitors for the treatment of human cytomegalovirus-associated disease

Zeligs, Michael A

PATENT: WO 2006047716 ISSUE DATE: 20060504

APPLICATION: 2005 PP: 71 pp.

ASSIGNEE: (Bioresponse LLC, USA

36. 49102 OI-LS-351; SCIFINDER-OI-6/20/2006

Preparation of nucleoside-lipid conjugates as antiviral and antitumor agents

Ahmad, Moghis U, Ali, Shoukath M, Khan, Abdul R, and Ahmad, Imran

PATENT: WO 2006029081 ISSUE DATE: 20060316

APPLICATION: 2005 PP: 72 pp.

ASSIGNEE: (Neopharm, Inc. USA

37. 49103 OI-LS-351; WOS-OI-6/18/2006

Biological activity of Tat (47-58) peptide on human pathogenic fungi

Jung, HJ, Park, Y, Hahm, KS, and Lee, DG



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