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1. 59191 OI-LS-359; SCIFINDER-OI-10/9/2006

Lysophosphatidic acid enhances antimycobacterial activity both in vitro and ex vivo

Garg, SK, Valente, E, Greco, E, Santucci, MB, De Spirito, M, Papi, M, Bocchino, M, Saltini, C, and Fraziano, M

Clinical Immunology (San Diego, CA, United States) 2006. 121(1): 23-28

2. 59192 OI-LS-359; SCIFINDER-OI-10/9/2006

Novel 1,2,4-triazole-3-mercaptoacetic acid derivatives as potential anti-mycobacterial and antimicrobial agents

El-Koussi, Nawal A and Abdel-Rahman, Hamdy M

Bulletin of Pharmaceutical Sciences, Assiut University 2006. 29(1): 127-136

3. 59193 OI-LS-359; PUBMED-OI-10/16/2006

Pyrrolidine Carboxamides as a Novel Class of Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis

He, X, Alian, A, Stroud, R, and Ortiz, de Montellano PR

J Med Chem 2006. 49(21): 6308-6323


4. 59194 OI-LS-359; PUBMED-OI-10/16/2006

Molecular and therapeutic advances in the management of chronic hepatitis B and C

McCarron, B, Main, J, and Thomas, HC

Curr Opin Infect Dis 1998. 11(5): 555-64


5. 59195 OI-LS-359; PUBMED-OI-10/16/2006

Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding

Sengupta, S, Shah, M, and Nagaraja, V

Nucleic Acids Res 2006.


6. 59196 OI-LS-359; PUBMED-OI-10/16/2006

Design, Synthesis, and Biological Evaluation of beta-Ketosulfonamide Adenylation Inhibitors as Potential Antitubercular Agents

Vannada, J, Bennett, EM, Wilson, DJ, Boshoff, HI, Barry, CE 3rd, and Aldrich, CC

Org Lett 2006. 8(21): 4707-10


7. 59197 OI-LS-359; PUBMED-OI-10/16/2006

New insights into DHFR interactions: Analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions

Cody, V, Pace, J, Chisum, K, and Rosowsky, A

Proteins 2006.


8. 59198 OI-LS-359; PUBMED-OI-10/16/2006

In Vitro and in Vivo Activities of HQQ-3, a New Triazole Antifungal Agent

Zhao, JX, Cao, YY, Quan, H, Liu, CM, He, QQ, Wu, QY, Gao, PH, Cao, YB, Liu, WX, and Jiang, YY

Biol Pharm Bull 2006. 29(10): 2031-4


9. 59199 OI-LS-359; PUBMED-OI-10/16/2006

Screening for anti-infective properties of several medicinal plants of the Mauritians flora

Rangasamy, O, Raoelison, G, Rakotoniriana, FE, Cheuk, K, Urverg-Ratsimamanga, S, Quetin-Leclercq, J, Gurib-Fakim, A, and Subratty, AH

J Ethnopharmacol 2006.


10. 59200 OI-LS-359; PUBMED-OI-10/16/2006

Novel non-classical C9-methyl-5-substituted-2,4-diaminopyrrolo[2,3-d]pyrimidines as potential inhibitors of dihydrofolate reductase and as anti-opportunistic agents

Gangjee, A, Yang, J, and Queener, SF

Bioorg Med Chem 2006.


11. 59201 OI-LS-359; SCIFINDER-OI-10/9/2006

Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages

Lee, Chiang W, Bennouna, Soumaya, and Denkers, Eric Y

Infection and Immunity 2006. 74(3): 1916-1923

12. 59202 OI-LS-359; SCIFINDER-OI-10/9/2006

Synthesis and antimicrobial activity of novel 2-methyl-3-(1'3'4'-thiadiazoyl)-4-(3H) quinazolinones

Jatav, Varsha, Jain, SK, Kashaw, SK, and Mishra, P

Indian Journal of Pharmaceutical Sciences 2006. 68(3): 360-363

13. 59203 OI-LS-359; SCIFINDER-OI-10/9/2006

Azoles: mode of antifungal action and resistance development. Effect of miconazole on endogenous reactive oxygen species production in Candida albicans

Francois, Isabelle EJA, Cammue, Bruno PA, Borgers, Marcel, Ausma, Jannie, Dispersyn, Gerrit D, and Thevissen, Karin

Anti-Infective Agents in Medicinal Chemistry 2006. 5(1): 3-13

14. 59204 OI-LS-359; SCIFINDER-OI-10/9/2006

Tensidols, new potentiators of antifungal miconazole activity, produced by Aspergillus niger FKI-2342

Fukuda, Takashi, Hasegawa, Yoko, Hagimori, Keiichi, Yamaguchi, Yuichi, Masuma, Rokuro, Tomoda, Hiroshi, and Omura, Satoshi

Journal of Antibiotics 2006. 59(8): 480-485

15. 59205 OI-LS-359; SCIFINDER-OI-10/9/2006

Synthesis and biological evaluation of a novel series of 2-(4-chloro-3-methylphenoxy)acetyl amino acids and peptides

Dahiya, Rajiv, Pathak, Davender, and Bhatt, Sunita

Journal of Saudi Chemical Society 2006. 10(1): 165-176

16. 59206 OI-LS-359; SCIFINDER-OI-10/9/2006

Antifungal Activity from 14-Helical b-Peptides

Karlsson, Amy J, Pomerantz, William C, Weisblum, Bernard, Gellman, Samuel H, and Palecek, Sean P

Journal of the American Chemical Society 2006. 128(39): 12630-12631

17. 59207 OI-LS-359; SCIFINDER-OI-10/9/2006

Synthesis, antimicrobial and anticancer activities of 2-substituted acetamido-4-ethoxycarbonylmethyl-1,3-thiazoles

Altintas, H, Ates, O, Gursoy, A, Birteksoz, S, and Otuk, G

Journal of Faculty of Pharmacy of Istanbul University 2006. 38(1): 57-63

18. 59208 OI-LS-359; SCIFINDER-OI-10/9/2006

Unify QSAR approach to antimicrobials. Part 1: Predicting antifungal activity against different species

Gonzalez-Diaz, Humberto, Prado-Prado, Francisco J, Santana, Lourdes, and Uriarte, Eugenio

Bioorganic & Medicinal Chemistry 2006. 14(17): 5973-5980

19. 59209 OI-LS-359; SCIFINDER-OI-10/9/2006

Synthesis and Antifungal Activity of a Novel Series of Alkyldimethylamine Cyanoboranes and Their Derivatives

Takrouri, Khuloud, Oren, Gal, Polacheck, Itzhack, Sionov, Edward, Shalom, Eli, Katzhendler, Jehoshua, and Srebnik, Morris

Journal of Medicinal Chemistry 2006. 49(16): 4879-4885

20. 59210 OI-LS-359; PUBMED-OI-10/16/2006

Transcriptional autoregulation by Mycobacterium tuberculosis PhoP involves recognition of novel direct repeat sequences in the regulatory region of the promoter

Gupta, S, Sinha, A, and Sarkar, D

FEBS Lett 2006. 580(22): 5328-38


21. 59211 OI-LS-359; PUBMED-OI-10/16/2006

Inhibition of hepatitis C virus gene expression by small interfering RNAs using a tri-cistronic full-length viral replicon and a transient mouse model

Kim, M, Shin, D, Kim, SI, and Park, M

Virus Res 2006.


22. 59212 OI-LS-359; SCIFINDER-OI-10/9/2006

In vitro antibacterial, antifungal and cytotoxic activity of some isonicotinoylhydrazide Schiff's bases and their cobalt(II), copper(II), nickel(II) and zinc(II) complexes

Chohan, Zahid H, Arif, M, Shafiq, Zahid, Yaqub, Muhammad, and Supuran, Claudiu T

Journal of Enzyme Inhibition and Medicinal Chemistry 2006. 21(1): 95-103

23. 59213 OI-LS-359; SCIFINDER-OI-10/9/2006

Studies on synthesis and evaluation of quantitative structure-activity relationship of 10-methyl-6-oxo-5-arylazo-6,7-dihydro-5H-[1,3]azaphospholo[1,5-d][1,4]benzodiazepin-2-phospha-3-ethoxycarbonyl-1-phosphorus dichlorides

Kumar, Ashok, Sharma, Pratibha, Gurram, VK, and Rane, Nilesh

Bioorganic & Medicinal Chemistry Letters 2006. 16(9): 2484-2491

24. 59214 OI-LS-359; SCIFINDER-OI-10/9/2006

Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-l-valyl-(4r)-4-[(6-methoxy-1-isoquinolinyl)oxy]-l-prolyl-1-amino-n-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt and uses for anti-HCV therapy

Sausker, Justin B and Scola, Paul Michael

PATENT: US 2006199773 ISSUE DATE: 20060907

APPLICATION: 39 PP: 16pp., Cont.-in-part of U.S. Ser. No. 295,914.


25. 59215 OI-LS-359; SCIFINDER-OI-10/9/2006

Preparation of 1,1-dioxido-4H-1,2,4-thiadiazines as hepatitis C polymerase inhibitors and anti-infective agents

Klein, Larry, Huang, Peggy-pei-Yu, Randolph, John T, Hutchinson, Douglas K, Yeung, Ming C, and Flentge, Charles A

PATENT: WO 2006093801 ISSUE DATE: 20060908

APPLICATION: 2006 PP: 172pp.

ASSIGNEE: (Abbott Laboratories, USA

26. 59216 OI-LS-359; WOS-OI-10/8/2006

rpoB gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis isolates from Shandong Province, China

Ma, X, Wang, HY, Deng, YF, Liu, ZM, Xu, Y, Pan, X, Musser, JM, and Graviss, EA

JOURNAL OF CLINICAL MICROBIOLOGY 2006. 44(9): 3409-3412, 4


27. 59217 OI-LS-359; SCIFINDER-OI-10/9/2006

Preparation and HCV anti-viral activity of bicyclo-[3.1.0]-hexane prodrugs

Jacobson, Kenneth Alan, Mackman, Richard L, and Joshi, Bhalchandra V

PATENT: WO 2006091905 ISSUE DATE: 20060831

APPLICATION: 2006 PP: 87pp.

ASSIGNEE: (Gilead Sciences, Inc. USA

28. 59218 OI-LS-359; SCIFINDER-OI-10/9/2006

Preparation of 2-thienylacetylenes as antiviral agents

Wunberg, Tobias, Baumeister, Judith, Gottschling, Dirk, Henninger, Kerstin, Koletzki, Diana, Pernerstorfer, Josef, Urban, Andreas, Birkmann, Alexander, Harrenga, Axel, and Lobell, Mario

PATENT: DE 102004061746 ISSUE DATE: 20060706

APPLICATION: 2004 PP: 26 pp.

ASSIGNEE: (Bayer Healthcare A.-G., Germany

29. 59219 OI-LS-359; SCIFINDER-OI-10/9/2006

Serial propagation of the microsporidian Enterocytozoon bieneusi of human origin in immunocompromised rodents

Feng, Xiaochuan, Akiyoshi, Donna E, Sheoran, Abhineet, Singh, Inderpal, Hanawalt, Joel, Zhang, Quanshun, Widmer, Giovanni, and Tzipori, Saul

Infection and Immunity 2006. 74(8): 4424-4429

30. 59220 OI-LS-359; SCIFINDER-OI-10/9/2006

Diagnosis and manifestation of encephalitozoonosis in mice after experimental infection with different species and application of dexamethasone

Herich, R, Levkutova, M, Kokincakova, T, Reiterova, K, Hipikova, V, and Levkut, M

Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 2006. 53(7): 340-345

31. 59221 OI-LS-359; WOS-OI-10/8/2006

Search of antitubercular activities in tetrahydroacridines: Synthesis and biological evaluation

Tripathi, RP, Verma, SS, Pandey, J, Agarwal, KC, Chaturvedi, V, Manju, YK, Srivastva, AK, Gaikwad, A, and Sinha, S



32. 59222 OI-LS-359; SCIFINDER-OI-10/9/2006

Functional characterization of a putative aquaporin from Encephalitozoon cuniculi, a microsporidia pathogenic to humans

Ghosh, Kaya, Cappiello, Clint D, McBride, Sean M, Occi, James L, Cali, Ann, Takvorian, Peter M, McDonald, Thomas V, and Weiss, Louis M

International Journal for Parasitology 2006. 36(1): 57-62

33. 59223 OI-LS-359; WOS-OI-10/8/2006

Nonclassical 5-Alkyl-6-substitutedarylthio-pyrrolo[2,3-d]pyrimidines as potent and selective Toxoplasma gondii dihydrofolate reductase inhibitors

Gangjee, A, Jain, HD, Kisliuk, RL, and Queener, SF



34. 59224 OI-LS-359; WOS-OI-10/16/2006

Adenosine kinase from Cryptosporidium parvum

Galazka, J, Striepen, B, and Ullman, B



35. 59225 OI-LS-359; WOS-OI-10/16/2006

Bird flu, influenza and 1918: The case for mutant Avian tuberculosis

Broxmeyer, L

MEDICAL HYPOTHESES 2006. 67(5): 1006-1015, 10


36. 59226 OI-LS-359; WOS-OI-10/16/2006

Conformational analysis of R207910, a new drug candidate for the treatment of tuberculosis, by a combined NMR and molecular modeling approach

Gaurrand, S, Desjardins, S, Meyer, C, Bonnet, P, Argoullon, JM, Oulyadi, H, and Guillemont, J

CHEMICAL BIOLOGY & DRUG DESIGN 2006. 68(2): 77-84, 8


37. 59227 OI-LS-359; WOS-OI-10/16/2006

Discovery of synthetic penaeidin activity against antibiotic-resistant fungi

Cuthbertson, BJ, Bullesbach, EE, and Gross, PS

CHEMICAL BIOLOGY & DRUG DESIGN 2006. 68(2): 120-127, 8


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