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1. 61356 OI-LS-379; SCIFINDER-OI-7/16/2007

Compositions and methods using carbon monoxide dehydrogenase inhibitors for the prevention, treatment and detection of tuberculosis and other diseases

Leishman, Kathryn

PATENT: US 2007148689 ISSUE DATE: 20070628

APPLICATION: 2007-48436 PP: 21pp., Cont.-in-part of U.S. Ser. No. 265,190.


2. 61357 OI-LS-379; WOS-OI-7/13/2007

Novel Simple Efficient Synthetic Approach Toward 6-Substituted-2h-[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazole-3-Thiones and First Synthesis and Biological Evaluation of N- and S-Beta-D-Glucosides of the [1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazole Ring System

Khalil, N.

Nucleosides Nucleotides & Nucleic Acids 2007. 26(4): 347-359


3. 61358 OI-LS-379; SCIFINDER-OI-7/16/2007

Synthesis of novel substituted pyrazolyl-2-toluidinomethanethione and pyrazolyl-2-methoxyanilinomethanethione as potential antitubercular agents

Ali, Mohamed Ashraf and Yar, Mohammad Shahar

Acta Pol. Pharm. 2007. 64(2): 139-146

4. 61359 OI-LS-379; SCIFINDER-OI-7/16/2007

Synthesis and antitubercular activity of substituted novel pyrazoline derivatives

Ali Mohamed Ashraf, Yar Mohammad Shahar, Kumar Mahesh, and Pandian Ganesan Suresh

Nat Prod Res 2007. 21(7): 575-9.

5. 61360 OI-LS-379; SCIFINDER-OI-7/16/2007

Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis

Sriram Dharmarajan, Yogeeswari Perumal, Dinakaran Murugesan, and Thirumurugan Rathinasababathy

J Antimicrob Chemother 2007. 59(6): 1194-6.

6. 61361 OI-LS-379; SCIFINDER-OI-7/16/2007

Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation

Reynolds, Robert C, Campbell, Shiela R, Fairchild, Ralph G, Kisliuk, Roy L, Micca, Peggy L, Queener, Sherry F, Riordan, James M, Sedwick, WDavid, Waud, William R, Leung, Adelaine KW, Dixon, Richard W, Suling, William J, and Borhani, David W

J. Med. Chem. 2007. 50(14): 3283-3289

7. 61362 OI-LS-379; SCIFINDER-OI-7/16/2007

Synthesis and antifungal activity of triazole derivatives with side chain containing tert-butyl and 4-substituted-piperazin-1-yl

He, Qiu-qin, Liu, Chao-mei, Li, Ke, Cao, Yong-bing, Zhao, Li-hua, and Dong, Huan-wen

Dier Junyi Daxue Xuebao 2007. 28(2): 179-182

8. 61363 OI-LS-379; SCIFINDER-OI-7/16/2007

Bioassay-guided isolation of antifungal alkaloids from Melochia odorata

Emile, Aurelie, Waikedre, Jean, Herrenknecht, Christine, Fourneau, Christophe, Gantier, Jean-Charles, Hnawia, Edouard, Cabalion, Pierre, Hocquemiller, Reynald, and Fournet, Alain

Phytother. Res. 2007. 21(4): 398-400

9. 61364 OI-LS-379; WOS-OI-7/13/2007

Pharmacokinetics and Metabolism of the Prodrug Db289 (2,5-Bis[4-(N-Methoxyamidino)Phenyl]Furan Monomaleate) in Rat and Monkey and Its Conversion to the Antiprotozoal/Antifungal Drug Db75 (2,5-Bis(4-Guanylphenyl)Furan Dihydrochloride)

Midgley, I. et al.

Drug Metabolism and Disposition 2007. 35(6): 955-967


10. 61365 OI-LS-379; SCIFINDER-OI-7/16/2007

Antiviral 2-carboxy-thiophene compounds

Corfield, John Andrew, Grimes, Richard Martin, Harrison, David, Hartley, Charles David, Howes, Peter David, Le, Joelle, Meeson, Malcolm Lees, Mordaunt, Jacqueline Elizabeth, Shah, Pritom, Slater, Martin John, and White, Gemma Victoria

PATENT: WO 2007071434 ISSUE DATE: 20070628

APPLICATION: 2006 PP: 155pp.

ASSIGNEE: (Smithkline Beecham Corporation, USA

11. 61366 OI-LS-379; WOS-OI-7/20/2007

Qsar Study of Antimicrobial Activity of Some 3-Nitrocoumarins and Related Compounds

Debeljak, Z. et al.

Journal of Chemical Information and Modeling 2007. 47(3): 918-926


12. 61367 OI-LS-379; WOS-OI-7/20/2007

Investigation of Beta-Amino Acids as Building Blocks in Hepatitis C Virus Ns3 Protease Inhibitors

Nurbo, J. et al.

Biopolymers 2007. 88(4): 580


13. 61368 OI-LS-379; WOS-OI-7/20/2007

Amper: a Database and an Automated Discovery Tool for Antimicrobial Peptides

Fjell, C., Hancock, R., and Cherkasov, A.

Bioinformatics 2007. 23(9): 1148-1155


14. 61369 OI-LS-379; PUBMED-OI-7/23/2007

Barriers to reaching the targets for tuberculosis control: multidrug-resistant tuberculosis

Blondal, K

Bull World Health Organ 2007. 85(5): 387-390


15. 61370 OI-LS-379; PUBMED-OI-7/23/2007

Reaching the targets for tuberculosis control: the impact of HIV

Laserson, K and Wells, C

Bull World Health Organ 2007. 85(5): 377-381


16. 61371 OI-LS-379; PUBMED-OI-7/23/2007

Did we reach the 2005 targets for tuberculosis control?

Dye, C, Hosseini, M, and Watt, C

Bull World Health Organ 2007. 85(5): 364-369


17. 61372 OI-LS-379; PUBMED-OI-7/23/2007

A New Dihydroagarofuranoid Sesquiterpene from Microtropis fokienensis with Antituberculosis Activity

Chou, TH, Chen, IS, Sung, PJ, Peng, CF, Shieh, PC, and Chen, JJ

Chem Biodivers 2007. 4(7): 1594-1600


18. 61373 OI-LS-379; PUBMED-OI-7/23/2007

New Insight into the Mechanism of Action of and Resistance to Isoniazid: Interaction of Mycobacterium tuberculosis enoyl-ACP Reductase with INH-NADP

Argyrou, A, Vetting, MW, and Blanchard, JS

J Am Chem Soc 2007.


19. 61374 OI-LS-379; PUBMED-OI-7/23/2007

Fragment-Based Substrate Activity Screening Method for the Identification of Potent Inhibitors of the Mycobacterium tuberculosis Phosphatase PtpB

Soellner, MB, Rawls, KA, Grundner, C, Alber, T, and Ellman, JA

J Am Chem Soc 2007.


20. 61375 OI-LS-379; PUBMED-OI-7/23/2007

Rv1106c from Mycobacterium tuberculosis Is a 3beta-Hydroxysteroid Dehydrogenase

Yang, X, Dubnau, E, Smith, I, and Sampson, NS

Biochemistry 2007.


21. 61376 OI-LS-379; PUBMED-OI-7/23/2007

Phase 2 study of the combination of merimepodib with peginterferon-alpha2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C

Marcellin, P, Horsmans, Y, Nevens, F, Grange, JD, Bronowicki, JP, Vetter, D, Purdy, S, Garg, V, Bengtsson, L, McNair, L, and Alam, J

J Hepatol 2007.


22. 61377 OI-LS-379; PUBMED-OI-7/23/2007

Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro

Strobl, JS, Cassell, M, Mitchell, SM, Reilly, CM, and Lindsay, DS

J Parasitol 2007. 93(3): 694-700


23. 61378 OI-LS-379; PUBMED-OI-7/23/2007

Encapsulation of moxifloxacin within poly(butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis

Kisich, KO, Gelperina, S, Higgins, MP, Shipulo, E, Oganesyan, E, and Heifets, L

Int J Pharm 2007.


24. 61379 OI-LS-379; PUBMED-OI-7/23/2007

Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171

Iwatsuki, M, Uchida, R, Takakusagi, Y, Matsumoto, A, Jiang, CL, Takahashi, Y, Arai, M, Kobayashi, S, Matsumoto, M, Inokoshi, J, Tomoda, H, and Omura, S

J Antibiot (Tokyo) 2007. 60(6): 357-63


25. 61380 OI-LS-379; PUBMED-OI-7/23/2007

WHO launches plan to fight drug resistant tuberculosis

Moszynski, P

BMJ 2007. 334(7608): 1340-1


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