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1. 61665 OI-LS-383; SCIFINDER-OI-9/10/2007

Programs to facilitate tuberculosis drug discovery: the Tuberculosis Antimicrobial Acquisition and Coordinating Facility

Goldman, RC, Laughon, BE, Reynolds, RC, Secrist, JA III, Maddry, JA, Guie, M-A, Poffenberger, AC, Kwong, CA, and Ananthan, S

Infect. Disord.: Drug Targets 2007. 7(2): 92-104

2. 61666 OI-LS-383; SCIFINDER-OI-9/10/2007

Anti-mycobacterial formulation

Parrish, Nicole M, Owens, Albert H Jr, and Dick, James D

PATENT: WO 2007092590 ISSUE DATE: 20070816

APPLICATION: 2007 PP: 38pp.

ASSIGNEE: (Fasgen, Inc. USA

3. 61667 OI-LS-383; SCIFINDER-OI-9/10/2007

Novel agents in the management of Mycobacterium tuberculosis disease

Barry, PJ and O'Connor, TM

Curr. Med. Chem. 2007. 14(18): 2000-2008

4. 61668 OI-LS-383; SCIFINDER-OI-9/10/2007

Resazurin reduction assays for screening of anti-tubercular compounds against dormant and actively growing Mycobacterium tuberculosis, Mycobacterium bovis BCG and Mycobacterium smegmatis

Taneja, Neetu Kumra and Tyagi, Jaya Sivaswami

J. Antimicrob. Chemother. 2007. 60(2): 288-293

5. 61669 OI-LS-383; SCIFINDER-OI-9/10/2007

Recombinant Mycobacterium tuberculosis antigen multi-epitope and applications for treatment of tuberculosis

Deng, Anmei, Zhong, Renqian, Lou, Jiatao, Wu, Chuanyong, Chen, Sunxiao, Zhou, Ye, Chen, Yan, Chen, Bo, Jiang, Tianshu, and Gu, Mingli

PATENT: CN 1900111 ISSUE DATE: 20070124

APPLICATION: 1002-9287 PP: 32pp.

ASSIGNEE: (Second Military Medical University, The Chinese People's Liberation Army Peop. Rep. China

6. 61670 OI-LS-383; WOS-OI-9/7/2007

Antimicrobial Activity of the Methanolic Extract and of the Chemical Constituents Isolated From Newbouldia Laevis

Kuete, V. et al.

Pharmazie 2007. 62(7): 552-556


7. 61671 OI-LS-383; SCIFINDER-OI-9/10/2007

Synthesis and biological evaluations of new benzofuran 1,3,5-trisubstituted pyrazoline derivatives of paracetamol as potential antitubercular, antimicrobial agents

Agarwal, YK, Manna, K, Bhatt, H, Gogai, P, Babu, VH, and Srinivasan, KK

Indian J. Heterocycl. Chem. 2007. 16(3): 263-266

8. 61672 OI-LS-383; WOS-OI-9/7/2007

Immunotherapeutics for Tuberculosis in Experimental Animals: Is There a Common Pathway Activated by Effective Protocols?

Rook, G., Lowrie, D., and Hernandez-Pando, R.

Journal of Infectious Diseases 2007. 196(2): 191-198


9. 61673 OI-LS-383; WOS-OI-9/7/2007

Genornics and the Evolution, Pathogenesis, and Diagnosis of Tuberculosis

Ernst, J., Trevejo-Nunez, G., and Banaiee, N.

Journal of Clinical Investigation 2007. 117(7): 1738-1745


10. 61674 OI-LS-383; SCIFINDER-OI-9/10/2007

In vitro antimicrobial and cytotoxic activities of ferrocene derivative compounds

Al-Bari, MAbdul Alim, Hossen, MFaruk, Khan, Alam, Islam, MRobiul, Kudrat-E-Zahan, M, Mosaddik, MAshik, Zakaria, Choudhury M, and Islam, MAnwar Ul

Pak. J. Biol. Sci. 2007. 10(15): 2423-2429

11. 61675 OI-LS-383; SCIFINDER-OI-9/10/2007

New sphingolipids with a previously unreported 9-methyl-C20-sphingosine moiety from a marine algous endophytic fungus Aspergillus niger EN-13

Zhang, Yi, Wang, Song, Li, Xiao-Ming, Cui, Chuan-Ming, Feng, Chao, and Wang, Bin-Gui

Lipids 2007. 42 (8): 759-764

12. 61676 OI-LS-383; WOS-OI-9/7/2007

Antimycobacterial Activity of Novel 1-(5-Cyclobutyl-1,3-Oxazol-2-Yl)-3-(Sub)Phenyl/Pyridylthiourea Compounds Endowed With High Activity Toward Multidrug-Resistant Mycobacterium Tuberculosis

Sriram, D. et al.

Journal of Antimicrobial Chemotherapy 2007. 59(6): 1194-1196


13. 61677 OI-LS-383; SCIFINDER-OI-9/10/2007

Synthesis and antifungal activity of some azole derivatives

Bakht, Mohammad Afroz, Mojahidul-Islam, and Siddiqui, Anees A

Orient. J. Chem. 2007. 23(1): 283-286

14. 61678 OI-LS-383; SCIFINDER-OI-9/10/2007

Fungicidal-fungistatic action of some 2-aril-thiazol compounds

Palage, Mariana, Parvu, M, Oniga, Smaranda, and Muresan, Ana

Farmacia (Bucharest, Rom.) 2007. 55(2): 203-206

15. 61679 OI-LS-383; SCIFINDER-OI-9/10/2007

Detection of in vitro anti-fungal activity of 20 tetralin compounds

Liang, Rong-mei, Cao, Yong-bing, Zhou, You-jun, Wang, Tao, Lu, Jia, Yao, Bin, and Jiang, Yuan-ying

Dier Junyi Daxue Xuebao 2007. 28(3): 286-293

16. 61680 OI-LS-383; SCIFINDER-OI-9/10/2007

Synthesis of O-b-D-Glucopyranosides of 7-Hydroxy-3-(imidazol-2-yl)-4H-chromen-4-ones

Ingle, VN, Hatzade, KM, Taile, VS, Gaidhane, PK, and Kharche, ST

J. Carbohydr. Chem. 2007. 26(2): 107-123

17. 61681 OI-LS-383; SCIFINDER-OI-9/10/2007

In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH2 alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans

Barchiesi, Francesco, Giacometti, Andrea, Cirioni, Oscar, Arzeni, Daniela, Silvestri, Carmela, Kamysz, Wojciech, Abbruzzetti, Alessandra, Riva, Alessandra, Kamysz, Elzbieta, and Scalise, Giorgio

Peptides (N. Y., NY, U. S.) 2007. 28(8): 1509-1513

18. 61682 OI-LS-383; WOS-OI-9/7/2007

Efficient Regulation of Viral Replication by Sirna in a Non-Human Primate Surrogate Model for Hepatitis C

Yokota, T. et al.

Biochemical and Biophysical Research Communications 2007. 361(2): 294-300


19. 61683 OI-LS-383; SCIFINDER-OI-9/10/2007

The priorities for antiviral drug resistance surveillance and research

Pillay, Deenan

J. Antimicrob. Chemother. 2007. 60(Suppl. 1): i57-i58

20. 61684 OI-LS-383; SCIFINDER-OI-9/10/2007

Heterocyclic antiviral compounds

Fell, Jay Bradford, Mohr, Peter, and Stengel, Peter J

PATENT: WO 2007093541 ISSUE DATE: 20070823

APPLICATION: 2007 PP: 53pp.

ASSIGNEE: (F. Hoffmann-La Roche A.-G., Switz.

21. 61685 OI-LS-383; SCIFINDER-OI-9/10/2007

Preparation of alkynyl nucleosides via Sonogashira coupling and palladium/copper-catalyzed alkynylation reaction as antiviral agents

Fairlamb, Ian James Stewart, Baumann, Christoph George, and Firth, Andrew Graeme

PATENT: WO 2007091056 ISSUE DATE: 20070816

APPLICATION: 2007 PP: 71pp.

ASSIGNEE: (The University of York, UK and Replizyme Limited)

22. 61686 OI-LS-383; WOS-OI-9/14/2007

Antibacterial Activity of Ergosterol Peroxide Against Mycobacterium Tuberculosis: Dependence Upon System and Medium Employed

Duarte, N. et al.

Phytotherapy Research 2007. 21(7): 601-604


23. 61687 OI-LS-383; WOS-OI-9/14/2007

Antibacterial Activity of Two Canthin-6-One Alkaloids From Allium Neapolitanum

O'donnell, G. and Gibbons, S.

Phytotherapy Research 2007. 21(7): 653-657


24. 61688 OI-LS-383; WOS-OI-9/14/2007

Large Compound Databases for Structure-Activity Relationships Studies in Drug Discovery

Scior, T. et al.

Mini-Reviews in Medicinal Chemistry 2007. 7(8): 851-860


25. 61689 OI-LS-383; WOS-OI-9/14/2007

Synthesis and Microbial Evaluation of Novel N(1)-Arilidene-N(2)-T(3)-Methyl-R(2), C(6)-Diaryl-Piperidin-4-One Azine Derivatives

Jayabharathi, J. et al.

Medicinal Chemistry Research 2007. 15(7-8): 431-442


26. 61690 OI-LS-383; WOS-OI-9/14/2007

Differential Requirements of Ns4a for Internal Ns3 Cleavage and Polyprotein Processing of Hepatitis C Virus

Kou, Y. et al.

Journal of Virology 2007. 81(15): 7999-8008


27. 61691 OI-LS-383; WOS-OI-9/14/2007

Synthesis of the Docosanasaccharide Arabinan Domain of Mycobacterial Arabinogalactan and a Proposed Octadecasaccharide Biosynthetic Precursor

Joe, M. et al.

Journal of the American Chemical Society 2007. 129(32): 9885-9901


28. 61692 OI-LS-383; WOS-OI-9/14/2007

New Tuberculosis Therapeutics: a Growing Pipeline

Spigelman, M.

Journal of Infectious Diseases 2007. 196: S28-S34


29. 61693 OI-LS-383; WOS-OI-9/14/2007

Targeting Enzyme Inhibitors in Drug Discovery

Copeland, R., Harpel, M., and Tummino, P.

Expert Opinion on Therapeutic Targets 2007. 11(7): 967-978



30. 61694 OI-LS-383; WOS-OI-9/14/2007

Structure-Based Approaches to Drug Discovery Against Tuberculosis

Holton, S. et al.

Current Protein & Peptide Science 2007. 8(4): 365-375


31. 61695 OI-LS-383; WOS-OI-9/14/2007

Pharmacophore-Based Screening for the Successful Identification of Bio-Active Natural Products

Langer, T. et al.

Chimia 2007. 61 (6): 350-354


32. 61696 OI-LS-383; PUBMED-OI-9/17/2007

Small Molecule Scaffolds for CYP51 Inhibitors Identified by High Throughput Screening and Defined by X-Ray Crystallography

Podust, LM, von, Kries JP, Eddine, AN, Kim, Y, Yermalitskaya, LV, Kuehne, R, Ouellet, H, Warrier, T, Altekoster, M, Lee, JS, Rademann, J, Oschkinat, H, Kaufmann, SH, and Waterman, MR

Antimicrob Agents Chemother 2007.


33. 61697 OI-LS-383; PUBMED-OI-9/17/2007

Targeted drug delivery to enhance efficacy and shorten treatment duration in disseminated Mycobacterium avium infection in mice

de Steenwinkel, JE, van Vianen, W, Ten Kate, MT, Verbrugh, HA, van Agtmael, MA, Schiffelers, RM, and Bakker-Woudenberg, IA

J Antimicrob Chemother 2007.


34. 61698 OI-LS-383; PUBMED-OI-9/17/2007

Antimalarial and Antituberculous Poly-O-acylated Jatrophane Diterpenoids from Pedilanthus tithymaloides

Mongkolvisut, W and Sutthivaiyakit, S

J Nat Prod 2007.


35. 61699 OI-LS-383; PUBMED-OI-9/17/2007

A novel mechanism for substrate inhibition in mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase

Burton, RL, Chen, S, Xu, XL, and Grant, GA

J Biol Chem 2007.


36. 61700 OI-LS-383; PUBMED-OI-9/17/2007

Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila

Tasdemir, D, Brun, R, Franzblau, SG, Sezgin, Y, and Calis, I

Phytomedicine 2007.


37. 61701 OI-LS-383; PUBMED-OI-9/17/2007

Activity against drug resistant-tuberculosis strains of plants used in Mexican traditional medicine to treat tuberculosis and other respiratory diseases

Camacho-Corona, MD, Ramirez-Cabrera, MA, Santiago, OG, Garza-Gonzalez, E, Palacios, ID, and Luna-Herrera, J

Phytother Res 2007.



38. 61702 OI-LS-383; PUBMED-OI-9/17/2007

Fatty Acid Synthesis Is Essential for Survival of Cryptococcus neoformans and a Potential Fungicidal Target

Chayakulkeeree, M, Rude, TH, Toffaletti, DL, and Perfect, JR

Antimicrob Agents Chemother 2007.


39. 61703 OI-LS-383; PUBMED-OI-9/17/2007

PEG-interferon alpha-2b for acute hepatitis C: a review

Palumbo, E

Mini Rev Med Chem 2007. 7(8): 839-843


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