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Opportunistic Infections Citation List:

October 1 - October 14, 2008

Opportunistic Protozoa (including pneumocystis, cryptosporidium, toxoplasma, microsporidia [encephalitozoon, enterocytozoon, vittaforma])

1. Gangjee A, Adair OO, Pagley M, Queener SF.

N9-substituted 2,4-diaminoquinazolines: synthesis and biological evaluation of lipophilic inhibitors of pneumocystis carinii and toxoplasma gondii dihydrofolate reductase.

J Med Chem. 2008 Oct 9;51(19):6195-200. Epub 2008 Sep 5.

PMID: 18771252 [PubMed - in process]

2. Bolstad DB, Bolstad ES, Frey KM, Wright DL, Anderson AC.

Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium.

J Med Chem. 2008 Oct 4. [Epub ahead of print]

PMID: 18834108 [PubMed - as supplied by publisher]

3. Strobl JS, Seibert CW, Li Y, Nagarkatti R, Mitchell SM, Rosypal AC, Rathore D, Lindsay DS.

Inhibition of Toxoplasma gondii and Plasmodium falciparum infections in vitro by NSC3852, a redox active anti-proliferative and tumor cell differentiation agent.

J Parasitol. 2008 Oct 6:1. [Epub ahead of print]

PMID: 18837587 [PubMed - as supplied by publisher]

4. Gangjee A, Adair OO, Pagley M, Queener SF.

N9-substituted 2,4-diaminoquinazolines: synthesis and biological evaluation of lipophilic inhibitors of pneumocystis carinii and toxoplasma gondii dihydrofolate reductase.

J Med Chem. 2008 Oct 9;51(19):6195-200. Epub 2008 Sep 5.

PMID: 18771252 [PubMed - in process]

5. Choi KM, Gang J, Yun J.

Anti-Toxoplasma gondii RH strain activity of herbal extracts used in traditional medicine.

Int J Antimicrob Agents. 2008 Oct;32(4):360-2. Epub 2008 Jul 10.

PMID: 18619816 [PubMed - in process]

TB (Tuberculosis, Mycobacterium, Avium, Drug Resistant, MAC, MDR)

6. Rivers EC, Mancera RL.

New anti-tuberculosis drugs in clinical trials with novel mechanisms of action.

Drug Discov Today. 2008 Oct 4. [Epub ahead of print]

PMID: 18840542 [PubMed - as supplied by publisher]

7. Cho Y, Ioerger TR, Sacchettini JC.

Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening.

J Med Chem. 2008 Oct 9;51(19):5984-92. Epub 2008 Sep 9.

PMID: 18778048 [PubMed - in process]

8. Cosconati S, Hong JA, Novellino E, Carroll KS, Goodsell DS, Olson AJ.

Structure-Based Virtual Screening and Biological Evaluation of Mycobacterium tuberculosis Adenosine 5'-Phosphosulfate Reductase Inhibitors.

J Med Chem. 2008 Oct 15. [Epub ahead of print]

PMID: 18855373 [PubMed - as supplied by publisher]

9. Mao J, Eoh H, He R, Wang Y, Wan B, Franzblau SG, Crick DC, Kozikowski AP.

Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase.

Bioorg Med Chem Lett. 2008 Oct 1;18(19):5320-3. Epub 2008 Aug 14.

PMID: 18783951 [PubMed - in process]

10. Hurdle JG, Lee RB, Budha NR, Carson EI, Qi J, Scherman MS, Cho SH, McNeil MR, Lenaerts AJ, Franzblau SG, Meibohm B, Lee RE.

A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents.

J Antimicrob Chemother. 2008 Nov;62(5):1037-45. Epub 2008 Aug 7.

PMID: 18693235 [PubMed - in process]

11. Kurabachew M, Lu SH, Krastel P, Schmitt EK, Suresh BL, Goh A, Knox JE, Ma NL, Jiricek J, Beer D, Cynamon M, Petersen F, Dartois V, Keller T, Dick T, Sambandamurthy VK.

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis.

J Antimicrob Chemother. 2008 Oct;62(4):713-9. Epub 2008 Jun 27.

PMID: 18587134 [PubMed - in process]

12. Kumar A, Siddiqi MI.

CoMFA based de novo design of pyrrolidine carboxamides as inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis.

J Mol Model. 2008 Oct;14(10):923-35. Epub 2008 Jul 15.

PMID: 18626672 [PubMed - in process]

Antimicrobials, Antifungals (General)

13. Pietka-Ottlik M, Wójtowicz-Młochowska H, Kołodziejczyk K, Piasecki E, Młochowski J. 

New Organoselenium Compounds Active against Pathogenic Bacteria, Fungi and Viruses.

Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1423-7.

PMID: 18827382 [PubMed - in process]

14. Lamani DS, Venugopala Reddy KR, Bhojya Naik HS, Savyasachi A, Naik HR.

Synthesis and DNA binding studies of novel heterocyclic substituted quinoline schiff bases: a potent antimicrobial agent.

Nucleosides Nucleotides Nucleic Acids. 2008 Oct;27(10):1197-210.

PMID: 18788049 [PubMed - in process]

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