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Opportunistic Infections Citation List:

July 22, 2009 - August 4, 2009

Opportunistic Fungi (Cryptococcus, Aspergillus, Candida, Histoplasma)

1. Synthesis of New Linear Guanidines and Macrocyclic Amidinourea Derivatives Endowed with High Antifungal Activity against Candida spp. and Aspergillus spp.

Manetti F, Castagnolo D, Raffi F, Zizzari AT, Rajamäki S, D'Arezzo S, Visca P, Cona A, Fracasso ME, Doria D, Posteraro B, Sanguinetti M, Fadda G, Botta M.

J Med Chem. 2009 Aug 3. [Epub ahead of print]

2. Identification of novel cell wall destabilizing antifungal compounds using a conditional Aspergillus nidulans protein kinase C mutant.

Mircus G, Hagag S, Levdansky E, Sharon H, Shadkchan Y, Shalit I, Osherov N.

J Antimicrob Chemother. 2009 Jul 31. [Epub ahead of print]

PMID: 19648579 [PubMed - as supplied by publisher]

TB (Tuberculosis, Mycobacterium, Avium, Drug Resistant, MAC, MDR)

3. Castagnolo, D., et al., Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones. Bioorg Med Chem, 2009. 17(15): p. 5716-21 http://www.ncbi.nlm.nih.gov/pubmed/19581099?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.

4. Fassihi, A., et al., Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2,6-dimethyl-N3,N5-bisaryl-1,4-dihydropyridine-3,5-dicarboxamides. Eur J Med Chem, 2009. 44(8): p. 3253-8 http://www.ncbi.nlm.nih.gov/pubmed/19371979?ordinalpos=15&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.

5. Molina-Salinas, G.M., et al., Antituberculosis activity of natural and semisynthetic azorellane and mulinane diterpenoids. Fitoterapia, 2009 http://www.ncbi.nlm.nih.gov/pubmed/19635530?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.

6. Pandey, J., et al., Synthesis and antitubercular screening of imidazole derivatives. Eur J Med Chem, 2009. 44(8): p. 3350-5 http://www.ncbi.nlm.nih.gov/pubmed/19272678?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.

7. Petrelli, R., et al., Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues. Bioorg Med Chem, 2009. 17(15): p. 5656-64 http://www.ncbi.nlm.nih.gov/pubmed/19596199?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.

8. Zalavadiya, P., et al., Multi-component synthesis of dihydropyrimidines by iodine catalyst at ambient temperature and in-vitro antimycobacterial activity. Arch Pharm (Weinheim), 2009. 342(8): p. 469-75 http://www.ncbi.nlm.nih.gov/pubmed/19565601?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.

Antimicrobials, Antifungals (General)

9. Antitubercular activity of alpha,omega-diaminoalkanes, H(2)N(CH(2))(n)NH(2).

Vergara FM, Henriques MD, Candea AL, Wardell JL, De Souza MV.

Bioorg Med Chem Lett. 2009 Jul 22. [Epub ahead of print]

PMID: 19648006 [PubMed - as supplied by publisher]

10. Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones.

Zhu B, Marinelli BA, Goldschmidt R, Foleno BD, Hilliard JJ, Bush K, Macielag MJ.

Bioorg Med Chem Lett. 2009 Jul 22. [Epub ahead of print]

PMID: 19646867 [PubMed - as supplied by publisher]

11. Novel broad-spectrum bis-(imidazolinylindole) derivatives with potent antibacterial activity against antibiotic-resistant strains.

Panchal RG, Ulrich RL, Lane D, Butler MM, Houseweart C, Opperman T, Williams JD, Peet NP, Moir DT, Nguyen T, Gussio R, Bowlin T, Bavari S.

Antimicrob Agents Chemother. 2009 Jul 27. [Epub ahead of print]

PMID: 19635954 [PubMed - as supplied by publisher]

Citations from the ISI Web of Knowledge Listings for O.I.

12. Walton, JGA, et al.

Synthesis and biological evaluation of functionalized tetrahydro-beta-carboline analogues as inhibitors of Toxoplasma gondii invasion

ORGANIC & BIOMOLECULAR CHEMISTRY 2009 7: 3049 - 3060

13. Gutierrez-Lugo, MT, et al.

Dequalinium, a New Inhibitor of Mycobacterium tuberculosis Mycothiol Ligase Identified by High-Throughput Screening

JOURNAL OF BIOMOLECULAR SCREENING 2009 (July) 14: 643 - 652

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