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Opportunistic Infections Citation List:

September 30, 2009 -October 13, 2009

Opportunistic protozoa COMPOUNDS (including pneumocystis, cryptosporidium, toxoplasma, microsporidia [encephalitozoon, enterocytozoon, vittaforma])

1. Polyamine Transport as a Target for Pneumocystis Pneumonia Therapy.

Liao CP, Phanstiel O 4th, Lasbury ME, Zhang C, Shao S, Durant PJ, Cheng BH, Lee CH.

Antimicrob Agents Chemother. 2009 Oct 5. [Epub ahead of print]

PMID: 19805570 [PubMed - as supplied by publisher]

ANTIFUNGAL COMPOUNDS ( includes Cryptococcus, Aspergillus, Candida, & Histoplasma)

2. Combination Testing of MGCD290, a Hos2 Histone Deacetylase Inhibitor, with Azole Antifungals against Opportunistic Fungal Pathogens.

Pfaller MA, Messer SA, Georgopapadakou N, Martell LA, Besterman JM, Diekema DJ.

J Clin Microbiol. 2009 Sep 30. [Epub ahead of print]

PMID: 19794038 [PubMed - as supplied by publisher]

3. Puupehanol, a sesquiterpene-dihydroquinone derivative from the marine sponge Hyrtios sp.

Xu WH, Ding Y, Jacob MR, Agarwal AK, Clark AM, Ferreira D, Liang ZS, Li XC.

Bioorg Med Chem Lett. 2009 Nov 1;19(21):6140-3. Epub 2009 Sep 11.

PMID: 19783432 [PubMed - in process]

4. 2-Amino-3-(oxirane-2,3-dicarboxamido)-propanoyl-valine an effective peptide antibiotic from the epiphyte Pantoea agglomerans 48b/90.

Sammer UF, Völksch B, Möllmann U, Schmidtke M, Spiteller P, Spiteller M, Spiteller D.

Appl Environ Microbiol. 2009 Oct 9. [Epub ahead of print]

PMID: 19820144 [PubMed - as supplied by publisher]

ANTIBACTERIAL COMPOUNDS (includes Mycobacterium spp., Drug Resistant, MAC, MDR)

5. de Carvalho, L.P., G. Lin, X. Jiang, and C. Nathan, Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance. J Med Chem, 2009. 52(19): p. 5789-92; PMID[19736929]

6. Del Olmo, E., G.M. Molina-Salinas, R. Escarcena, M. Alves, J.L. Lopez-Perez, R. Hernandez-Pando, S. Said-Fernandez, and A.S. Feliciano, Simple dihydrosphyngosine analogues with potent activity against MDR-Mycobacterium tuberculosis. Bioorg Med Chem Lett, 2009. 19(19): p. 5764-8; PMID[19703769]

7. Feese, E. and R.A. Ghiladi, Highly efficient in vitro photodynamic inactivation of Mycobacterium smegmatis. J Antimicrob Chemother, 2009. 64(4): p. 782-5; PMID[19661130]

8. Ferreira Mde, L., T.R. Vasconcelos, E.M. de Carvalho, M.C. Lourenco, S.M. Wardell, J.L. Wardell, V.F. Ferreira, and M.V. de Souza, Synthesis and antitubercular activity of novel Schiff bases derived from d-mannitol. Carbohydr Res, 2009. 344(15): p. 2042-7; PMID[19709650]

9. Guo, S., S.K. Tipparaju, S.D. Pegan, B. Wan, S. Mo, J. Orjala, A.D. Mesecar, S.G. Franzblau, and A.P. Kozikowski, Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents. Bioorg Med Chem, 2009. 17(20): p. 7126-30; PMID[19783449]

10. Huang, Q., J. Mao, B. Wan, Y. Wang, R. Brun, S.G. Franzblau, and A.P. Kozikowski, Searching for New Cures for Tuberculosis: Design, Synthesis, and Biological Evaluation of 2-Methylbenzothiazoles. J Med Chem, 2009; PMID[19817445]

Citations from the ISI Web of Knowledge Listings for O.I.

11. Cardoso, SH., et al



Quimica Nova (Brazil) 2009 32: 1557 - 1560

12. Lin, G., et al

Inhibitors selective for mycobacterial versus human proteasomes

NATURE 2009 (Sept. 16) 461: 621 -626

13. Kossakowski, J., et al

Synthesis of new derivatives of 2,2-dimethyl-2,3-dihydro-7-benzo[b]furanol with potential antimicrobial activity

MEDICINAL CHEMISTRY RESEARCH 2009 (Sept.) 18: 555 - 565

14. Larson, ET., et al

Toxoplasma gondii Cathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl

JOURNAL OF BIOLOGICAL CHEMISTRY 2009 (Sept.) 284: 26839 - 26850

15. Wang, WY., et al

Discovery of highly potent novel antifungal azoles by structure-based rational design


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