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Opportunistic Infections Citation List:

April 1- April 15, 2010

OPPORTUNISTIC PROTOZOA COMPOUNDS (including pneumocystis, cryptosporidium, toxoplasma, microsporidia [encephalitozoon, enterocytozoon, vittaforma])

1. Thiazole, Oxadiazole, and Carboxamide Derivatives of Artemisinin are Highly Selective and Potent Inhibitors of Toxoplasma gondii. Hencken, C.P., L. Jones-Brando, C. Bordon, R. Stohler, B.T. Mott, R. Yolken, G.H. Posner, and L.E. Woodard. J Med Chem. [Epub ahead of print]; PMID[20373807].

[Pubmed]. OI_0402-041510.

2. Toxoplasma gondii: fluconazole and itraconazole activity against toxoplasmosis in a murine model. Martins-Duarte, E.S., L. Lemgruber, W. de Souza, and R.C. Vommaro. Exp Parasitol. 124(4): p. 466-9; PMID[20045696].

[Pubmed]. OI_0402-041510.

ANTIFUNGAL COMPOUNDS ( includes Cryptococcus, Aspergillus, Candida, & Histoplasma)

3. Antimicrobial selaginellin derivatives from Selaginella pulvinata. Cao, Y., J.J. Chen, N.H. Tan, L. Oberer, T. Wagner, Y.P. Wu, G.Z. Zeng, H. Yan, and Q. Wang. Bioorg Med Chem Lett. 20(8): p. 2456-60; PMID[20335035].

[Pubmed]. OI_0402-041510.

4. Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides. Guzel, O., A. Maresca, R.A. Hall, A. Scozzafava, A. Mastrolorenzo, F.A. Muhlschlegel, and C.T. Supuran. Bioorg Med Chem Lett. 20(8): p. 2508-11; PMID[20299219].

[Pubmed]. OI_0402-041510.

ANTIBACTERIAL COMPOUNDS (includes Mycobacterium spp., Drug Resistant, MAC, MDR)

5. Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines. Aponte, J.C., A.J. Vaisberg, D. Castillo, G. Gonzalez, Y. Estevez, J. Arevalo, M. Quiliano, M. Zimic, M. Verastegui, E. Malaga, R.H. Gilman, J.M. Bustamante, R.L. Tarleton, Y. Wang, S.G. Franzblau, G.F. Pauli, M. Sauvain, and G.B. Hammond. Bioorg Med Chem. 18(8): p. 2880-6; PMID[20356752].

[Pubmed]. OI_0402-041510.

6. In Vitro Activities of DC-159a, a New-generation Fluoroquinolone, against Mycobacterium species. Disratthakit, A. and N. Doi. Antimicrob Agents Chemother. [Epub ahead of print]; PMID[20368403].

[Pubmed]. OI_0402-041510.

7. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. Dutta, N.K., S. Mehra, and D. Kaushal. PLoS One. 5(4): p. e10069; PMID[20386700].

[Pubmed]. OI_0402-041510.

8. Fluorescent 3-hydroxy-4-pyridinone hexadentate iron chelators: intracellular distribution and the relevance to antimycobacterial properties. Nunes, A., M. Podinovskaia, A. Leite, P. Gameiro, T. Zhou, Y. Ma, X. Kong, U.E. Schaible, R.C. Hider, and M. Rangel. J Biol Inorg Chem. [Epub ahead of print]; PMID[20364296].

[Pubmed]. OI_0402-041510.

9. Secondary Metabolites from the Roots of Litsea hypophaea and Their Antitubercular Activity. Pan, P.C., M.J. Cheng, C.F. Peng, H.Y. Huang, J.J. Chen, and I.S. Chen. J Nat Prod. [Epub ahead of print]; PMID[20384293].

[Pubmed]. OI_0402-041510.

10. In vitro interactions between new anti-tubercular drug candidates SQ109 and TMC207. Reddy, V.M., L. Einck, K. Andries, and C.A. Nacy. Antimicrob Agents Chemother. [Epub ahead of print]; PMID[20385864].

[Pubmed]. OI_0402-041510.

Citations from the ISI Web of Knowledge Listings for O.I.

11. Dry Powder PA-824 Aerosols for Treatment of Tuberculosis in Guinea Pigs. Garcia-Contreras, L., J.C. Sung, P. Muttil, D. Padilla, M. Telko, J.L. VerBerkmoes, K.J. Elbert, A.J. Hickey, and D.A. Edwards. Antimicrobial Agents and Chemotherapy. 54(4): p. 1436-1442; ISI[000275662700006].

[WOS]. OI_0402-041510.

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