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Other Viruses Citation List: February 4, 2009 - February 17, 2009

Hepatitis Virus

1. Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor.
Li H, Tatlock J, Linton A, Gonzalez J, Jewell T, Patel L, Ludlum S, Drowns M, Rahavendran SV, Skor H, Hunter R, Shi ST, Herlihy KJ, Parge H, Hickey M, Yu X, Chau F, Nonomiya J, Lewis C.
J Med Chem. 2009 Feb 11. [Epub ahead of print]
PMID: 19209845 [PubMed - as supplied by publisher]

2. Amidinoanthracyclines - a new group of potential anti-hepatitis C virus compounds.
Krawczyk M, Wasowska-Lukawska M, Oszczapowicz I, Boguszewska-Chachulska AM.
Biol Chem. 2009 Feb 7. [Epub ahead of print]
PMID: 19199832 [PubMed - as supplied by publisher]

3. Second-Generation Highly Potent and Selective Inhibitors of the Hepatitis C Virus NS3 Serine Protease.
Chen KX, Nair L, Vibulbhan B, Yang W, Arasappan A, Bogen SL, Venkatraman S, Bennett F, Pan W, Blackman ML, Padilla AI, Prongay A, Cheng KC, Tong X, Shih NY, Njoroge FG.
J Med Chem. 2009 Feb 5. [Epub ahead of print]
PMID: 19196021 [PubMed - as supplied by publisher]

4. Structure-Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle-Coumarin Conjugates.
Neyts J, Clercq ED, Singha R, Chang YH, Das AR, Chakraborty SK, Hong SC, Tsay SC, Hsu MH, Hwu JR.
J Med Chem. 2009 Feb 4. [Epub ahead of print]
PMID: 19193060 [PubMed - as supplied by publisher]

5. Novel potent inhibitors of hepatitis C virus (HCV) NS3 protease with cyclic sulfonyl P3 cappings.
Chen KX, Vibulbhan B, Yang W, Nair LG, Tong X, Cheng KC, Njoroge FG.
Bioorg Med Chem Lett. 2009 Feb 15;19(4):1105-1109. Epub 2009 Jan 8.
PMID: 19168351 [PubMed - as supplied by publisher]

 

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