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Other Viruses Citation List:

October 14, 2009 -October 27, 2009

Hepatitis C Virus

1. Novel Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease Featuring a 2-Amino-1,3-thiazole as a P4 Carbamate Replacement.

Di Francesco ME, Dessole G, Nizi E, Pace P, Koch U, Fiore F, Pesci S, Di Muzio J, Monteagudo E, Rowley M, Summa V.

J Med Chem. 2009 Oct 26. [Epub ahead of print]PMID: 19856919 [PubMed - as supplied by publisher]

2. Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.

Rondla R, Coats SJ, McBrayer TR, Grier J, Johns M, Tharnish PM, Whitaker T, Zhou L, Schinazi RF.

Antivir Chem Chemother. 2009 Oct 19;20(2):99-106.PMID: 19843980 [PubMed - in process]

3. MK-7009: A Potent and Selective Inhibitor of Hepatitis C Virus NS3/4A Protease.

Liverton NJ, Carroll SS, Dimuzio J, Fandozzi C, Graham DJ, Hazuda D, Holloway MK, Ludmerer SW, McCauley JA, McIntyre CJ, Olsen DB, Rudd MT, Stahlhut M, Vacca JP.

Antimicrob Agents Chemother. 2009 Oct 19. [Epub ahead of print]PMID: 19841155 [PubMed - as supplied by publisher]

4. Double-stranded RNA-activated protein kinase inhibits hepatitis C virus replication but may be not essential in interferon treatment.

Chang JH, Kato N, Muroyama R, Taniguchi H, Guleng B, Dharel N, Shao RX, Tateishi K, Jazag A, Kawabe T, Omata M.

Liver Int. 2009 Oct 16. [Epub ahead of print]PMID: 19840259 [PubMed - as supplied by publisher]

5. Hepatitis C virus NS3 protease is activated by low concentrations of protease inhibitors.

Dahl G, Arenas OG, Danielson UH.

Biochemistry. 2009 Oct 19. [Epub ahead of print]PMID: 19839643 [PubMed - as supplied by publisher]

6. Hepatitis C virus NS3 protease inhibitors: Large, flexible molecules of peptide origin shows satisfactory permeability across Caco-2 cells.

Bergström CA, Bolin S, Artursson P, Rönn R, Sandström A.

Eur J Pharm Sci. 2009 Oct 13. [Epub ahead of print]PMID: 19833201 [PubMed - as supplied by publisher]

7. Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA.

Parsons J, Castaldi MP, Dutta S, Dibrov SM, Wyles DL, Hermann T.

Nat Chem Biol. 2009 Nov;5(11):823-5. Epub 2009 Sep 20.PMID: 19767736 [PubMed - in process]

8. Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection.

Pan KL, Lee JC, Sung HW, Chang TY, Hsu JT.

Antimicrob Agents Chemother. 2009 Nov;53(11):4825-34. Epub 2009 Aug 31.PMID: 19721068 [PubMed - in process]


9. Dimethylthiazolidine carboxylic acid as a rigid p3 unit in inhibitors of serine proteases: application to two targets.

Kawai SH, Aubry N, Duceppe JS, Llinàs-Brunet M, LaPlante SR.

Chem Biol Drug Des. 2009 Nov;74(5):517-22. Epub 2009 Sep 22.

Citations from the ISI Web of Knowledge Listings for O.I.

10. Ellis, DA, et al.

5,5 '- and 6,6 '-Dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase


11. Kang, IJ, et al.

Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors


12. Pacini, B, et al.

2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp


Articles from Reviews We Abstracted

From Memo OV-LS-400, "Arbidol: A Broad-Spectrum Antiviral Compound that Blocks Viral Fusion":

13. Biochemical Mechanism of Hepatitis C Virus Inhibition by the Broad-Spectrum Antiviral Arbidol

Eve-Isabelle Pécheur, Dimitri Lavillette, Fanny Alcaras, Jennifer Molle, Yury S. Boriskin, Michael Roberts, François-Loïc Cosset, and Stephen J. Polyak

Biochemistry 2007, 46. pp 6050-6059

Publication Date (Web): April 25, 2007 (Article)

DOI: 10.1021/bi700181j

14. Arbidol: a broad-spectrum antiviral that inhibits acute and chronic HCV infectionYury S Boriskin, Eve-Isabelle Pécheur, Stephen J Polyak

Virology Journal 2006, 3:56 (19 July 2006)

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