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Other Viruses Citation List: June 21 - July 4, 2013

Hepatitis C Virus

1. Discovery of N-(4'-(Indol-2-yl)phenyl)sulfonamides as Novel Inhibitors of HCV Replication. Chen, G., H. Ren, A. Turpoff, A. Arefolov, R. Wilde, J. Takasugi, A. Khan, N. Almstead, Z. Gu, T. Komatsu, C. Freund, J. Breslin, J. Colacino, J. Hedrick, M. Weetall, and G.M. Karp. Bioorganic & Medicinal Chemistry Letters, 2013. 23(13): p. 3942-3946; PMID[23683596].

[PubMed] OV_0621-070413.


2. Valine, the Branched-chain Amino acid, Suppresses Hepatitis C Virus RNA Replication but Promotes Infectious Particle Formation. Ishida, H., T. Kato, K. Takehana, T. Tatsumi, A. Hosui, T. Nawa, T. Kodama, S. Shimizu, H. Hikita, N. Hiramatsu, T. Kanto, N. Hayashi, and T. Takehara. Biochemical and Biophysical Research Communications, 2013. [Epub ahead of print]; PMID[23806690].

[PubMed] OV_0621-070413.


3. Combination Therapies with NS5A, NS3 and NS5B Inhibitors on Different Genotypes of Hepatitis C Virus in Human Hepatocyte Chimeric Mice. Shi, N., N. Hiraga, M. Imamura, C.N. Hayes, Y. Zhang, K. Kosaka, A. Okazaki, E. Murakami, M. Tsuge, H. Abe, H. Aikata, S. Takahashi, H. Ochi, C. Tateno-Mukaidani, K. Yoshizato, H. Matsui, A. Kanai, T. Inaba, F. McPhee, M. Gao, and K. Chayama. Gut, 2013. 62(7): p. 1055-1061; PMID[23322441].

[PubMed] OV_0621-070413.


4. Discovery of Novel HCV Inhibitors: Synthesis and biological Activity of 6-(Indol-2-yl)pyridine-3-sulfonamides Targeting Hepatitis C Virus NS4B. Zhang, X., N. Zhang, G. Chen, A. Turpoff, H. Ren, J. Takasugi, C. Morrill, J. Zhu, C. Li, W. Lennox, S. Paget, Y. Liu, N. Almstead, F. George Njoroge, Z. Gu, T. Komatsu, V. Clausen, C. Espiritu, J. Graci, J. Colacino, F. Lahser, N. Risher, M. Weetall, A. Nomeir, and G.M. Karp. Bioorganic & Medicinal Chemistry Letters, 2013. 23(13): p. 3947-53; PMID[23683597]. [PubMed] OV_0621-070413.


5. Pegylated Interferon-alpha2b and Ribavirin Decrease Claudin-1 and E-Cadherin Expression in HepG2 and Huh-7.5 Cells. Rendon-Huerta, E.P., A. Torres-Martinez, C. Charles-Nino, A.M. Rivas-Estilla, A. Paez, T.I. Fortoul, and L.F. Montano. Annals of Hepatology, 2013. 12(4): p. 616-25; PMID[23813140].

[PubMed] OV_0621-070413.


6. Semisynthesis, Cytotoxicity, Antiviral Activity, and Drug Interaction Liability of 7-O-Methylated Analogues of Flavonolignans from Milk Thistle. Althagafy, H.S., T.N. Graf, A.A. Sy-Cordero, B.T. Gufford, M.F. Paine, J. Wagoner, S.J. Polyak, M.P. Croatt, and N.H. Oberlies. Bioorganic & Medicinal Chemistry, 2013. 21(13): p. 3919-3926; PMID[23673225].

[PubMed] OV_0621-070413.


7. Synthesis and Evaluation of a New Phosphorylated Ribavirin Prodrug. Dong, S.D., C.C. Lin, and M. Schroeder. Antiviral Research, 2013. 99(1): p. 18-26; PMID[23624267].

[PubMed] OV_0621-070413.

Human Cytomegalovirus

8. Development of Flavonoid-based Inverse Agonists of the Key Signaling Receptor US28 of Human Cytomegalovirus. Kralj, A., M.T. Nguyen, N. Tschammer, N. Ocampo, Q. Gesiotto, M.R. Heinrich, and O.t. Phanstiel. Journal of Medicinal Chemistry, 2013. 56(12): p. 5019-5032; PMID[23768434]. [PubMed] OV_0621-070413.


9. Artemisinin-derived Dimer Phosphate Esters as Potent Anti-cytomegalovirus (anti-CMV) and Anti-cancer Agents: A Structure-Activity Study. Mott, B.T., R. He, X. Chen, J.M. Fox, C.I. Civin, R. Arav-Boger, and G.H. Posner. Bioorganic & Medicinal Chemistry, 2013. 21(13): p. 3702-3707; PMID[23673218].

[PubMed] OV_0621-070413.

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