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1. 57828 DMID-LS-101; WOS-DMID-9/15/2005 ; DMID-LSLOAD

Celgosivir - Alpha-Glucosidase Inhibitor Anti-Hepatitis C Virus Drug

Sorbera, L., Castaner, J., and Garcia-Capdevila, L.

Drugs of the Future 2005. 30(6): 545-552


2. 57829 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Method for discovery and development of broad-spectrum antiviral drugs

Buscher, Benjamin A, Dyall, Julie, Jockel-Balsarotti, Jennifer I, O'Guin, Andrew K, Olivo, Paul D, Roth, Robert M, and Zhou, Yi

PATENT: US 2005164167 ISSUE DATE: 20050728

APPLICATION: 2004-45330 PP: 36 pp.


3. 57830 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

The therapeutic potential of NS3 protease inhibitors in HCV infection

Goudreau, N and Llinas-Brunet, M

Expert Opin Investig Drugs 2005. 14(9): 1129-44


4. 57831 DMID-LS-101; WOS-DMID-9/15/2005 ; DMID-LSLOAD

Inhibition of Hepatitis C Virus Translation and Subgenomic Replication by Sirnas Directed Against Highly Conserved Hcv Sequence and Cellular Hcv Cofactors

Korf, M. et al.

Journal of Hepatology 2005. 43(2): 225-234


5. 57832 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins

Nakagawa, M, Sakamoto, N, Tanabe, Y, Koyama, T, Itsui, Y, Takeda, Y, Chen, CH, Kakinuma, S, Oooka, S, Maekawa, S, Enomoto, N, and Watanabe, M

Gastroenterology 2005. 129(3): 1031-41


6. 57833 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Synthesis and antiviral activities of some 4,4'- and 2,2'-dihydroxytriphenylmethanes

Mibu, N, Yokomizo, K, Uyeda, M, and Sumoto, K

Chem Pharm Bull (Tokyo) 2005. 53(9): 1171-4


7. 57834 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system

Hwang, DR, Wu, YS, Chang, CW, Lien, TW, Chen, WC, Tan, UK, Hsu, JT, and Hsieh, HP

Bioorg Med Chem 2005.


8. 57835 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Antiviral activity and mode of action of caffeoylquinic acids from Schefflera heptaphylla (L.) Frodin

Li, Y, But, PP, and Ooi, VE

Antiviral Res 2005.


9. 57836 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Viral polymerase inhibitors

Tsantrizos, Youla S, Chabot, Catherine, Beaulieu, Pierre, Brochu, Christian, Poirier, Martin, Stammers, Timothy A, Thavonekham, Bounkham, and Rancourt, Jean

PATENT: WO 2005080388 ISSUE DATE: 20050901

APPLICATION: 2005 PP: 177 pp.

ASSIGNEE: (Boehringer Ingelheim International G.m.b.H., Germany and Boehringer Ingelheim Pharma G.m.b.H. & Co. K.-G.)

10. 57837 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides

Hocek, M, Naus, P, Pohl, R, Votruba, I, Furman, PA, Tharnish, PM, and Otto, MJ

J Med Chem 2005. 48(18): 5869-73


11. 57838 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases

Schnute, ME, Cudahy, MM, Brideau, RJ, Homa, FL, Hopkins, TA, Knechtel, ML, Oien, NL, Pitts, TW, Poorman, RA, Wathen, MW, and Wieber, JL

J Med Chem 2005. 48(18): 5794-804


12. 57839 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

In vitro antiviral activity of three enantiomeric sesquiterpene lactones from Senecio species against hepatitis B virus

Li, H, Zhou, C, Zhou, L, Chen, Z, Yang, L, Bai, H, Wu, X, Peng, H, and Zhao, Y

Antivir Chem Chemother 2005. 16(4): 277-82


13. 57840 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Synthesis and anti-rhinovirus properties of fluoro-substituted flavonoids

Conti, C, Mastromarino, P, Goldoni, P, Portalone, G, and Desideri, N

Antivir Chem Chemother 2005. 16(4): 267-76


14. 57841 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

HCV antiviral resistance: The impact of in vitro studies on the development of antiviral agents targeting the viral NS5B polymerase

Tomei, L, Altamura, S, Paonessa, G, De Francesco, R, and Migliaccio, G

Antivir Chem Chemother 2005. 16(4): 225-245


15. 57842 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

Yang, H, Xie, W, Xue, X, Yang, K, Ma, J, Liang, W, Zhao, Q, Zhou, Z, Pei, D, Ziebuhr, J, Hilgenfeld, R, Yuen, KY, Wong, L, Gao, G, Chen, S, Chen, Z, Ma, D, Bartlam, M, and Rao, Z

PLoS Biol 2005. 3(10): e324


16. 57843 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Conquering influenza: Recent advances in anti-influenza drug discovery

Luo, G, Cianci, C, Harte, W, and Krystal, M

IDrugs 1999. 2(7): 671-85


17. 57844 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Viral proteases and phosphorodiesterase inhibitors

Agathangelou, P

IDrugs 1999. 2(6): 523-5


18. 57845 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Design of a small-molecule entry inhibitor with activity against primary measles virus strains

Plemper, RK, Doyle, J, Sun, A, Prussia, A, Cheng, LT, Rota, PA, Liotta, DC, Snyder, JP, and Compans, RW

Antimicrob Agents Chemother 2005. 49(9): 3755-61


19. 57846 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Antiviral drugs: Triphosphates of nucleoside analogues active as antiviral drugs

De Clercq, Erik

Nucleoside Triphosphates and Their Analogs 2005. 329-341

20. 57847 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Structural analysis and antiviral activity of a sulfated galactan from the red seaweed Schizymenia binderi (Gigartinales, Rhodophyta)

Matsuhiro, B, Conte, AF, Damonte, EB, Kolender, AA, Matulewicz, MC, Mejias, EG, Pujol, CA, and Zuniga, EA

Carbohydr Res 2005.


21. 57848 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

New antivirals for herpesviruses

Eizuru, Yoshito

Uirusu 2005. 55 (1): 95-104

22. 57849 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system

Romero, MR, Efferth, T, Serrano, MA, Castano, B, Macias, RI, Briz, O, and Marin, JJ

Antiviral Res 2005.


23. 57850 DMID-LS-101; WOS-DMID-9/15/2005 ; DMID-LSLOAD

Design and Study of Novel Peptide Inhibitors Against Sars-Cov Entry

Yan, Z., Tripet, B., and Hodges, R.

Biopolymers 2005. 80(4): 499-500


24. 57851 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Therapy and prophylaxis of Ebola virus infections

Feldmann, H, Jones, SM, Schnittler, HJ , and Geisbert, T

Curr Opin Investig Drugs 2005. 6(8): 823-830


25. 57852 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol

Wyde, PR, Laquerre, S, Chetty, SN, Gilbert, BE, Nitz, TJ, and Pevear, DC

Antiviral Res 2005.


26. 57853 DMID-LS-101; WOS-DMID-9/15/2005 ; DMID-LSLOAD

Inhibition of Protein Kinases C Prevents Murine Cytomegalovirus Replication

Kucic, N., Mahmutefendic, H., and Lucin, P.

Journal of General Virology 2005. 86: 2153-2161


27. 57854 DMID-LS-101; PUBMED-DMID-9/15/2005 ; DMID-LSLOAD

Inhibition of the hepatitis B virus replication in vitro by an oligodeoxynucleotide containing cytidine-guanosine motifs

Li, N, Fan, XG, Chen, ZH, Zhu, C, Liu, HB, and Huang, Y

Immunol Lett 2005.


28. 57855 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Preparation of glutathione derivatives as antiviral agents

Benatti, Umberto, Brandi, Giorgio, Garaci, Enrico, Magnani, Mauro, Millo, Enrico, Palamara, Anna Teresa, and Rossi, Luigia

PATENT: WO 2005063795 ISSUE DATE: 20050714

APPLICATION: 2004 PP: 26 pp.


29. 57856 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses

Fleming, Ronald A, Hes, Jan V, Huang, Yunsheng, Read, Russ H, Morris-Natschke, Susan L, Ishaq, Khalid S, Kucera, Louis S, and Furman, Phillip A

PATENT: US 2005187192 ISSUE DATE: 20050825

APPLICATION: 2004-63031 PP: 36 pp.

ASSIGNEE: (Kucera Pharmaceutical Company, USA

30. 57857 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Antiviral activity of cisplatin derivatives of methotrexate against vaccinia virus, varicella zoster virus (VZV), reovirus ST3, and herpes simplex virus (HSV-1)

Roner, Michael R, Carraher, Charles E Jr, and Dhanji, Salima

PMSE Preprints 2005. 93: 410-413

31. 57858 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Anti-SARS-coronavirus monoclonal antibodies, and diagnostic, therapeutic and vaccine preparation uses

Berry, Jody, Jones, Steven, Yuan, Xin Yong, Gubbins, Mike, Andonov, Anton, Weingarti, Hana, Drebot, Mike, and Plummer, Frank

PATENT: WO 2005054469 ISSUE DATE: 20050616

APPLICATION: 2004 PP: 75 pp.

ASSIGNEE: (Her Majesty the Queen in Right of Canada as Represented by the Minister of Health, Can.

32. 57859 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Mechanisms of imiquimod indirect antiviral activity

Hober, D, Ajram, L, Chehadeh, W, Lazrek, M, Goffard, A, Dewilde, A, and Wattre, P

Annales de Biologie Clinique 2005. 63(2): 155-163

33. 57860 DMID-LS-101; SCIFINDER-DMID-9/15/2005 ; DMID-LSLOAD

Polyamide compositions and therapeutic methods for treatment of human papilloma virus

Fisher, Chris, Bashkin, James K, Crowley, Kathleen S, Sverdrup, Francis M, Garner-Hamrick, Peggy A, and Phillion, Dennis P

PATENT: WO 2005033282 ISSUE DATE: 20050414

APPLICATION: 2004 PP: 53 pp.

ASSIGNEE: (Pharmacia & Upjohn Company LLC, USA

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