ONLINE DATABASE SEARCH - DMID-LS-105-MEMO
1. 57952 DMID-LS-105; WOS-DMID-11/7/2005 ; DMID-LSLOAD
N-4-Hydroxycytosine Dioxolane Nucleosides and Their Activity Against Hepatitis B Virus
Du, J. et al.
Nucleosides Nucleotides & Nucleic Acids 2005. 24(8): 1209-1214
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232691900005
2. 57953 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Pharmacological enhancement and manufacturing method of antiviral compound
Gong, Jiao and Jiang, Wei
PATENT: US 20050181075 ISSUE DATE: 20050818
APPLICATION: 2003-62990
ASSIGNEE: (USA)
3. 57954 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
NOVEL AND SPECIFIC INHIBITORS OF A POXVIRUS TYPE I TOPOISOMERASE
Bond, A, Reichert, Z, and Stivers, JT
Mol Pharmacol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16267207&dopt=abstract
4. 57955 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Structural insights into SARS coronavirus proteins
Bartlam, M, Yang, H, and Rao, Z
Curr Opin Struct Biol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16263266&dopt=abstract
5. 57956 DMID-LS-105; WOS-DMID-11/7/2005 ; DMID-LSLOAD
New Direct Antivirals Against Hepatitis C
Manns, M.
Antiviral Therapy 2004. 9(6): H11-H12
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231616000171
6. 57957 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Anti herpes simplex virus activity of lactoferrin/lactoferricin - an example of antiviral activity of antimicrobial protein/peptide
Jenssen, H
Cell Mol Life Sci 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16261265&dopt=abstract
7. 57958 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase
Laporte, MG, Lessen, TA, Leister, L, Cebzanov, D, Amparo, E, Faust, C, Ortlip, D, Bailey, TR, Nitz, TJ, Chunduru, SK, Young, DC, and Burns, CJ
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16260131&dopt=abstract
8. 57959 DMID-LS-105; WOS-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis and Study of Conformationally Restricted 3 '-Deoxy-3 ',4 '-Exo-Methylene Nucleoside Analogues
Gagneron, J., Gosselin, G., and Mathe, C.
Nucleosides Nucleotides & Nucleic Acids 2005. 24(5-7): 383-385
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232473500010
9. 57960 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
An N-Linked Glycoprotein with {alpha}(2,3)-Linked Sialic Acid Is a Receptor for BK Virus
Dugan, AS, Eash, S, and Atwood, WJ
J Virol 2005. 79(22): 14442-5
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16254379&dopt=abstract
10. 57961 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions
Krenn, BM, Holzer, B, Gaudernak, E, Triendl, A, van Kuppeveld, FJ, and Seipelt, J
J Virol 2005 . 79(22): 13892-13899
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16254325&dopt=abstract
11. 57962 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
A cell-based high-throughput assay for screening inhibitors of human papillomavirus-16 long control region activity
Lembo, D, Donalisio, M, De, Andrea M, Cornaglia, M, Scutera, S, Musso, T, and Landolfo, S
FASEB J 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16254045&dopt=abstract
12. 57963 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
A survey of antiviral drugs for bioweapons
Goff, Arthur J and Paragas, Jason
Antiviral Chemistry & Chemotherapy 2005. 16(5): 283-294
13. 57964 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Randomized, placebo-controlled trial of nonpegylated and pegylated forms of recombinant human alpha interferon 2a for suppression of dengue virus viremia in rhesus monkeys
Ajariyakhajorn, C, Mammen, MP Jr, Endy, TP, Gettayacamin, M, Nisalak, A, Nimmannitya, S, and Libraty, DH
Antimicrob Agents Chemother 2005. 49(11): 4508-4514
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16251289&dopt=abstract
14. 57965 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Rift valley fever virus NSs mRNA is transcribed from an incoming anti-viral-sense S RNA segment
Ikegami, Tetsuro, Won, Sungyong, Peters, CJ, and Makino, Shinji
Journal of Virology 2005. 79(18): 12106-12111
15. 57966 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
A New Lead for Nonpeptidic Active-Site-Directed Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus Main Protease Discovered by a Combination of Screening and Docking Methods
Kaeppler, U, Stiefl, N, Schiller, M, Vicik, R, Breuning, A, Schmitz, W, Rupprecht, D, Schmuck, C, Baumann, K, Ziebuhr, J, and Schirmeister, T
J Med Chem 2005. 48(22): 6832-6842
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16250642&dopt=abstract
16. 57967 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Design and Synthesis of Peptidomimetic Severe Acute Respiratory Syndrome Chymotrypsin-like Protease Inhibitors
Ghosh, AK, Xi, K, Ratia, K, Santarsiero, BD, Fu, W, Harcourt, BH, Rota, PA, Baker, SC, Johnson, ME, and Mesecar, AD
J Med Chem 2005. 48(22): 6767-6771
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16250632&dopt=abstract
17. 57968 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis and anti-hepatitis C virus activity of nucleoside derivatives of N3, 5'-anhydro-4-(beta-D-ribofuranosyl)-8-aza-purin-2-ones
Hassan, AE, Wang, P, McBrayer, TR, Tharnish, PM, Stuyver, LJ, Schinazi, RF, Otto, MJ, and Watanabe, KA
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 961-4
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248072&dopt=abstract
18. 57969 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one and its 3'-deoxysugar analogue as potential anti-hepatitis C virus agents
Wang, P, Hollecker, L, Pankiewicz, KW, Patterson, SE, Whitaker, T, McBrayer, TR, Tharnish, PM, Stuyver, LJ, Schinazi, RF, Otto, MJ, and Watanabe, KA
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 957-60
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248071&dopt=abstract
19. 57970 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis and evaluation of anti-HSV activity of new 5-alkynyl-2'-deoxyuridines
Pchelintseva, AA, Skorobogatyj, MV, Petrunina, AL, Andronova, VL, Galegov, GA, Astakhova, IV, Ustinov, AV, Malakhov, AD, and Korshun, VA
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 923-926
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248063&dopt=abstract
20. 57971 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis and in vitro anti-hcv activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides
Shi, J, Du, J, Ma, T, Pankiewicz, KW, Patterson, SE, Hassan, AE, Tharnish, PM, McBrayer, TR, Lostia, S, Stuyver, LJ, Watanabe, KA, Chu, CK, Schinazi, RF, and Otto, MJ
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 875-9
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248053&dopt=abstract
21. 57972 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Nm 283, an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine
Pierra, C, Benzaria, S, Amador, A, Moussa, A, Mathieu, S, Storer, R, and Gosselin, G
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 767-770
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248033&dopt=abstract
22. 57973 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Sense antiviral oligonucleotide analogs and method for treating ssRNA viral infection
Iversen, Patrick L
PATENT: WO 2005013905 ISSUE DATE: 20050217
APPLICATION: 2004 PP: 81 pp.
ASSIGNEE: (Avi Biopharma, Inc. USA
23. 57974 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents
Dukhan, D, Leroy, F, Peyronnet, J, Bosc, E, Chaves, D, Durka, M, Storer, R, La, Colla P, Seela, F, and Gosselin, G
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 671-4
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248011&dopt=abstract
24. 57975 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis and biological evaluation of N- and O-alkylated bicyclic furanopyrimidines as non-nucleosidic inhibitors of human cytomegalovirus
Kelleher, MR, McGuigan, C, Andrei, G, Snoeck, R, De Clercq, E, and Balzarini, J
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 639-641
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248003&dopt=abstract
25. 57976 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Targeted therapy of respiratory syncytial virus by 2-5A antisense
Cramer, H, Okicki, JR, Kuang, M, and Xu, Z
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 497-501
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16247978&dopt=abstract
26. 57977 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
West Nile virus replication interferes with both poly(I:C)-induced interferon gene transcription and response to interferon treatment
Scholle, Frank and Mason, Peter W
Virology 2005. 342(1): 77-87
27. 57978 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines
De Clercq, E, Andrei, G, Balzarini, J, Leyssen, P, Naesens, L, Neyts, J, Pannecouque, C, Snoeck, R, Ying, C, Hockova, D, and Holy, A
Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 331-341
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16247948&dopt=abstract
28. 57979 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors
Yin, Z, Patel, SJ, Wang, WL, Chan, WL, Ranga, Rao KR, Wang, G, Ngew, X, Patel, V, Beer, D, Knox, JE, Ma, NL, Ehrhardt, C, Lim, SP, Vasudevan, SG, and Keller, TH
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16246563&dopt=abstract
29. 57980 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead
Yin, Z, Patel, SJ, Wang, WL, Wang, G, Chan, WL, Rao, KR, Alam, J, Jeyaraj, DA, Ngew, X, Patel, V, Beer, D, Lim, SP, Vasudevan, SG, and Keller, TH
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16246553&dopt=abstract
30. 57981 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis and biological activity of 1H-benzotriazole and 1H-benzimidazole analogues--inhibitors of the NTpase/helicase of HCV and of some related Flaviviridae
Bretner, M, Baier, A, Kopanska, K, Najda, A, Schoof, A, Reinholz, M, Lipniacki, A, Piasek, A, Kulikowski, T, and Borowski, P
Antivir Chem Chemother 2005. 16(5): 315-326
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16245647&dopt=abstract
31. 57982 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Use of antiviral agents and other measures in an influenza pandemic
Groeneveld, K and van der Noordaa, J
Neth J Med 2005. 63(9): 339-343
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16244380&dopt=abstract
32. 57983 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Case history: Acyclic nucleoside phosphonates: a key class of antiviral drugs
De Clercq, Erik and Holy, Antonin
Nature Reviews Drug Discovery 2005. 4(11): 928-940
33. 57984 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Preparation of 9-(2-fatty acid ester ethoxymethyl)guanines as antiviral agents for treatment of hepatitis B virus and herpes virus
Zhou, Pei, Cai, Qinsheng, Huang, Hai, Li, Jiyang, and Zhou, Wei
PATENT: CN 1563007 ISSUE DATE: 20050112
APPLICATION: 1001-7500 PP: 14 pp.
ASSIGNEE: (Fudan University, Peop. Rep. China
34. 57985 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Preparation of imidazol-4-yl-N'-phenylureas as antiviral agents
Zimmermann, Holger, Brueckner, David, Heimbach, Dirk, Hendrix, Martin, Henninger, Kerstin, Hewlett, Guy, Rosentreter, Ulrich, Keldenich, Joerg, Lang, Dieter, and Radtke, Martin
PATENT: WO 2005092865 ISSUE DATE: 20051006
APPLICATION: 2005 PP: 124 pp.
ASSIGNEE: (Bayer Healthcare A.-G., Germany
35. 57986 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor
Martina, E, Stiefl, N, Degel, B, Schulz, F, Breuning, A, Schiller, M, Vicik, R, Baumann, K, Ziebuhr, J, and Schirmeister, T
Bioorg Med Chem Lett 2005. 15(24): 5365-9
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16216498&dopt=abstract
36. 57987 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Antiviral protein OVT102 derived from cyanovirin with improved properties and methods therefor
Levine, Howard L and Kerns, William
PATENT: WO 2005058229 ISSUE DATE: 20050630
APPLICATION: 2004 PP: 32 pp.
ASSIGNEE: (Omniviral Therapeutics LLC, USA
37. 57988 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure
Holden, KL, Stein, DA, Pierson, TC, Ahmed, AA, Clyde, K, Iversen, PL, and Harris, E
Virology 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16214197&dopt=abstract
38. 57989 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
A QSAR study on influenza neuraminidase inhibitors
Verma, RP and Hansch, C
Bioorg Med Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16213733&dopt=abstract
39. 57990 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD
Synthesis of C-6 substituted pyrazolo[1,5-a]pyridines with potent activity against herpesviruses
Allen, SH, Johns, BA, Gudmundsson, KS, Freeman, GA, Boyd, FL Jr, Sexton, CH, Selleseth, DW, Creech, KL, and Moniri, KR
Bioorg Med Chem 2005. 14: 944-954
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16213142&dopt=abstract
40. 57991 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model
Bartlett, Nathan W, Buttigieg, Karen, Kotenko, Sergei V, and Smith, Geoffrey L
Journal of General Virology 2005. 86(6): 1589-1596
41. 57992 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD
Method of regulating phosphorylation of sr protein and antiviral agents comprising sr protein activity regulator as the active ingredient
Hagiwara, Masatoshi, Fukuhara, Takeshi, Suzuki, Masaaki, and Hosoya, Takamitsu
PATENT: WO 2005063293 ISSUE DATE: 20050714
APPLICATION: 2004 PP: 122 pp.
ASSIGNEE: (Japan)