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ONLINE DATABASE SEARCH - DMID-LS-105-MEMO

1. 57952 DMID-LS-105; WOS-DMID-11/7/2005 ; DMID-LSLOAD

N-4-Hydroxycytosine Dioxolane Nucleosides and Their Activity Against Hepatitis B Virus

Du, J. et al.

Nucleosides Nucleotides & Nucleic Acids 2005. 24(8): 1209-1214


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232691900005


2. 57953 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Pharmacological enhancement and manufacturing method of antiviral compound

Gong, Jiao and Jiang, Wei

PATENT: US 20050181075 ISSUE DATE: 20050818

APPLICATION: 2003-62990

ASSIGNEE: (USA)


3. 57954 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

NOVEL AND SPECIFIC INHIBITORS OF A POXVIRUS TYPE I TOPOISOMERASE

Bond, A, Reichert, Z, and Stivers, JT

Mol Pharmacol 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16267207&dopt=abstract


4. 57955 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Structural insights into SARS coronavirus proteins

Bartlam, M, Yang, H, and Rao, Z

Curr Opin Struct Biol 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16263266&dopt=abstract


5. 57956 DMID-LS-105; WOS-DMID-11/7/2005 ; DMID-LSLOAD

New Direct Antivirals Against Hepatitis C

Manns, M.

Antiviral Therapy 2004. 9(6): H11-H12


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231616000171


6. 57957 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Anti herpes simplex virus activity of lactoferrin/lactoferricin - an example of antiviral activity of antimicrobial protein/peptide

Jenssen, H

Cell Mol Life Sci 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16261265&dopt=abstract



7. 57958 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase

Laporte, MG, Lessen, TA, Leister, L, Cebzanov, D, Amparo, E, Faust, C, Ortlip, D, Bailey, TR, Nitz, TJ, Chunduru, SK, Young, DC, and Burns, CJ

Bioorg Med Chem Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16260131&dopt=abstract


8. 57959 DMID-LS-105; WOS-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis and Study of Conformationally Restricted 3 '-Deoxy-3 ',4 '-Exo-Methylene Nucleoside Analogues

Gagneron, J., Gosselin, G., and Mathe, C.

Nucleosides Nucleotides & Nucleic Acids 2005. 24(5-7): 383-385


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232473500010


9. 57960 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

An N-Linked Glycoprotein with {alpha}(2,3)-Linked Sialic Acid Is a Receptor for BK Virus

Dugan, AS, Eash, S, and Atwood, WJ

J Virol 2005. 79(22): 14442-5


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16254379&dopt=abstract


10. 57961 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions

Krenn, BM, Holzer, B, Gaudernak, E, Triendl, A, van Kuppeveld, FJ, and Seipelt, J

J Virol 2005 . 79(22): 13892-13899


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16254325&dopt=abstract


11. 57962 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

A cell-based high-throughput assay for screening inhibitors of human papillomavirus-16 long control region activity

Lembo, D, Donalisio, M, De, Andrea M, Cornaglia, M, Scutera, S, Musso, T, and Landolfo, S

FASEB J 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16254045&dopt=abstract


12. 57963 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

A survey of antiviral drugs for bioweapons

Goff, Arthur J and Paragas, Jason

Antiviral Chemistry & Chemotherapy 2005. 16(5): 283-294



13. 57964 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Randomized, placebo-controlled trial of nonpegylated and pegylated forms of recombinant human alpha interferon 2a for suppression of dengue virus viremia in rhesus monkeys

Ajariyakhajorn, C, Mammen, MP Jr, Endy, TP, Gettayacamin, M, Nisalak, A, Nimmannitya, S, and Libraty, DH

Antimicrob Agents Chemother 2005. 49(11): 4508-4514


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16251289&dopt=abstract


14. 57965 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Rift valley fever virus NSs mRNA is transcribed from an incoming anti-viral-sense S RNA segment

Ikegami, Tetsuro, Won, Sungyong, Peters, CJ, and Makino, Shinji

Journal of Virology 2005. 79(18): 12106-12111


15. 57966 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

A New Lead for Nonpeptidic Active-Site-Directed Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus Main Protease Discovered by a Combination of Screening and Docking Methods

Kaeppler, U, Stiefl, N, Schiller, M, Vicik, R, Breuning, A, Schmitz, W, Rupprecht, D, Schmuck, C, Baumann, K, Ziebuhr, J, and Schirmeister, T

J Med Chem 2005. 48(22): 6832-6842


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16250642&dopt=abstract


16. 57967 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Design and Synthesis of Peptidomimetic Severe Acute Respiratory Syndrome Chymotrypsin-like Protease Inhibitors

Ghosh, AK, Xi, K, Ratia, K, Santarsiero, BD, Fu, W, Harcourt, BH, Rota, PA, Baker, SC, Johnson, ME, and Mesecar, AD

J Med Chem 2005. 48(22): 6767-6771


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16250632&dopt=abstract


17. 57968 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis and anti-hepatitis C virus activity of nucleoside derivatives of N3, 5'-anhydro-4-(beta-D-ribofuranosyl)-8-aza-purin-2-ones

Hassan, AE, Wang, P, McBrayer, TR, Tharnish, PM, Stuyver, LJ, Schinazi, RF, Otto, MJ, and Watanabe, KA

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 961-4


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248072&dopt=abstract



18. 57969 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one and its 3'-deoxysugar analogue as potential anti-hepatitis C virus agents

Wang, P, Hollecker, L, Pankiewicz, KW, Patterson, SE, Whitaker, T, McBrayer, TR, Tharnish, PM, Stuyver, LJ, Schinazi, RF, Otto, MJ, and Watanabe, KA

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 957-60


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248071&dopt=abstract


19. 57970 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis and evaluation of anti-HSV activity of new 5-alkynyl-2'-deoxyuridines

Pchelintseva, AA, Skorobogatyj, MV, Petrunina, AL, Andronova, VL, Galegov, GA, Astakhova, IV, Ustinov, AV, Malakhov, AD, and Korshun, VA

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 923-926


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248063&dopt=abstract


20. 57971 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis and in vitro anti-hcv activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides

Shi, J, Du, J, Ma, T, Pankiewicz, KW, Patterson, SE, Hassan, AE, Tharnish, PM, McBrayer, TR, Lostia, S, Stuyver, LJ, Watanabe, KA, Chu, CK, Schinazi, RF, and Otto, MJ

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 875-9


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248053&dopt=abstract


21. 57972 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Nm 283, an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine

Pierra, C, Benzaria, S, Amador, A, Moussa, A, Mathieu, S, Storer, R, and Gosselin, G

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 767-770


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248033&dopt=abstract


22. 57973 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Sense antiviral oligonucleotide analogs and method for treating ssRNA viral infection

Iversen, Patrick L

PATENT: WO 2005013905 ISSUE DATE: 20050217

APPLICATION: 2004 PP: 81 pp.

ASSIGNEE: (Avi Biopharma, Inc. USA



23. 57974 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents

Dukhan, D, Leroy, F, Peyronnet, J, Bosc, E, Chaves, D, Durka, M, Storer, R, La, Colla P, Seela, F, and Gosselin, G

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 671-4


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248011&dopt=abstract


24. 57975 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis and biological evaluation of N- and O-alkylated bicyclic furanopyrimidines as non-nucleosidic inhibitors of human cytomegalovirus

Kelleher, MR, McGuigan, C, Andrei, G, Snoeck, R, De Clercq, E, and Balzarini, J

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 639-641


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16248003&dopt=abstract


25. 57976 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Targeted therapy of respiratory syncytial virus by 2-5A antisense

Cramer, H, Okicki, JR, Kuang, M, and Xu, Z

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 497-501


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16247978&dopt=abstract


26. 57977 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

West Nile virus replication interferes with both poly(I:C)-induced interferon gene transcription and response to interferon treatment

Scholle, Frank and Mason, Peter W

Virology 2005. 342(1): 77-87


27. 57978 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines

De Clercq, E, Andrei, G, Balzarini, J, Leyssen, P, Naesens, L, Neyts, J, Pannecouque, C, Snoeck, R, Ying, C, Hockova, D, and Holy, A

Nucleosides Nucleotides Nucleic Acids 2005. 24(5-7): 331-341


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16247948&dopt=abstract



28. 57979 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors

Yin, Z, Patel, SJ, Wang, WL, Chan, WL, Ranga, Rao KR, Wang, G, Ngew, X, Patel, V, Beer, D, Knox, JE, Ma, NL, Ehrhardt, C, Lim, SP, Vasudevan, SG, and Keller, TH

Bioorg Med Chem Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16246563&dopt=abstract


29. 57980 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead

Yin, Z, Patel, SJ, Wang, WL, Wang, G, Chan, WL, Rao, KR, Alam, J, Jeyaraj, DA, Ngew, X, Patel, V, Beer, D, Lim, SP, Vasudevan, SG, and Keller, TH

Bioorg Med Chem Lett 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16246553&dopt=abstract


30. 57981 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis and biological activity of 1H-benzotriazole and 1H-benzimidazole analogues--inhibitors of the NTpase/helicase of HCV and of some related Flaviviridae

Bretner, M, Baier, A, Kopanska, K, Najda, A, Schoof, A, Reinholz, M, Lipniacki, A, Piasek, A, Kulikowski, T, and Borowski, P

Antivir Chem Chemother 2005. 16(5): 315-326


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16245647&dopt=abstract


31. 57982 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Use of antiviral agents and other measures in an influenza pandemic

Groeneveld, K and van der Noordaa, J

Neth J Med 2005. 63(9): 339-343


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16244380&dopt=abstract


32. 57983 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Case history: Acyclic nucleoside phosphonates: a key class of antiviral drugs

De Clercq, Erik and Holy, Antonin

Nature Reviews Drug Discovery 2005. 4(11): 928-940



33. 57984 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Preparation of 9-(2-fatty acid ester ethoxymethyl)guanines as antiviral agents for treatment of hepatitis B virus and herpes virus

Zhou, Pei, Cai, Qinsheng, Huang, Hai, Li, Jiyang, and Zhou, Wei

PATENT: CN 1563007 ISSUE DATE: 20050112

APPLICATION: 1001-7500 PP: 14 pp.

ASSIGNEE: (Fudan University, Peop. Rep. China


34. 57985 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Preparation of imidazol-4-yl-N'-phenylureas as antiviral agents

Zimmermann, Holger, Brueckner, David, Heimbach, Dirk, Hendrix, Martin, Henninger, Kerstin, Hewlett, Guy, Rosentreter, Ulrich, Keldenich, Joerg, Lang, Dieter, and Radtke, Martin

PATENT: WO 2005092865 ISSUE DATE: 20051006

APPLICATION: 2005 PP: 124 pp.

ASSIGNEE: (Bayer Healthcare A.-G., Germany


35. 57986 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor

Martina, E, Stiefl, N, Degel, B, Schulz, F, Breuning, A, Schiller, M, Vicik, R, Baumann, K, Ziebuhr, J, and Schirmeister, T

Bioorg Med Chem Lett 2005. 15(24): 5365-9


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16216498&dopt=abstract


36. 57987 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Antiviral protein OVT102 derived from cyanovirin with improved properties and methods therefor

Levine, Howard L and Kerns, William

PATENT: WO 2005058229 ISSUE DATE: 20050630

APPLICATION: 2004 PP: 32 pp.

ASSIGNEE: (Omniviral Therapeutics LLC, USA


37. 57988 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure

Holden, KL, Stein, DA, Pierson, TC, Ahmed, AA, Clyde, K, Iversen, PL, and Harris, E

Virology 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16214197&dopt=abstract



38. 57989 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

A QSAR study on influenza neuraminidase inhibitors

Verma, RP and Hansch, C

Bioorg Med Chem 2005.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16213733&dopt=abstract


39. 57990 DMID-LS-105; PUBMED-DMID-11/7/2005 ; DMID-LSLOAD

Synthesis of C-6 substituted pyrazolo[1,5-a]pyridines with potent activity against herpesviruses

Allen, SH, Johns, BA, Gudmundsson, KS, Freeman, GA, Boyd, FL Jr, Sexton, CH, Selleseth, DW, Creech, KL, and Moniri, KR

Bioorg Med Chem 2005. 14: 944-954


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16213142&dopt=abstract


40. 57991 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model

Bartlett, Nathan W, Buttigieg, Karen, Kotenko, Sergei V, and Smith, Geoffrey L

Journal of General Virology 2005. 86(6): 1589-1596


41. 57992 DMID-LS-105; SCIFINDER-DMID-11/7/2005 ; DMID-LSLOAD

Method of regulating phosphorylation of sr protein and antiviral agents comprising sr protein activity regulator as the active ingredient

Hagiwara, Masatoshi, Fukuhara, Takeshi, Suzuki, Masaaki, and Hosoya, Takamitsu

PATENT: WO 2005063293 ISSUE DATE: 20050714

APPLICATION: 2004 PP: 122 pp.

ASSIGNEE: (Japan)


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