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1. 58160 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Preclinical Pharmacokinetics and Metabolism of a Potent Non-Nucleoside Inhibitor of the Hepatitis C Virus Ns5b Polymerase

Giuliano, C. et al.

Xenobiotica 2005. 35(10-11): 1035-1054


2. 58161 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

Effective Inhibition of HBV Replication in Vivo by Anti-HBx Short Hairpin RNAs

Carmona, Sergio, Ely, Abdullah, Crowther, Carol, Moolla, Naazneen, Salazar, Felix H, Marion, Patricia L, Ferry, Nicolas, Weinberg, Marc S, and Arbuthnot, Patrick

Molecular Therapy 2006. 13(2): 411-421

3. 58162 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Antiviral Role for Indoleamine 2,3-Dioxygenase in Vivo in Vaginal Infection by West Nile Virus

Wu, W., Bao, S., and King, N.

Tissue Antigens 2005. 66(5): 464


4. 58163 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Synthesis and antiviral evaluation of novel 4'-hydroxymethyl branched apiosyl nucleosides

Kim, JW and Hong, JH

Nucleosides Nucleotides Nucleic Acids 2006. 25(1): 109-17


5. 58164 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Synthesis and antiviral screening of some thieno[2,3-d]pyrimidine nucleosides

Rashad, AE and Ali, MA

Nucleosides Nucleotides Nucleic Acids 2006. 25(1): 17-28


6. 58165 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Heterocyclic rimantadine analogues with antiviral activity

Zoidis, G, Fytas, C, Papanastasiou, I, Foscolos, GB, Fytas, G, Padalko, E, De Clercq, E, Naesens, L, Neyts, J, and Kolocouris, N

Bioorg Med Chem 2006.


7. 58166 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: inhibitory activity against the West Nile virus NTPase/helicase

Ujjinamatada, RK, Agasimundin, YS, Zhang, P, Hosmane, RS, Schuessler, R, Borowski, P, Kalicharran, K, and Fattom, A

Nucleosides Nucleotides Nucleic Acids 2005. 24(10-12): 1775-1788


8. 58167 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

Anti-viral uses of borinic acid complexes

Bellinger-Kawahara, Carolyn, Maples, Kirk R., and Plattner, Jacob J

PATENT: US 2006019927 ISSUE DATE: 20060126

APPLICATION: 2005-21887 PP: 20 pp.


9. 58168 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Novel yeast cell-based assay to screen for inhibitors of human cytomegalovirus protease in a high-throughput format

Cottier, V, Barberis, A, and Luthi, U

Antimicrob Agents Chemother 2006. 50(2): 565-571


10. 58169 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

ent-Epiafzelechin-(4{alpha}->8)-epiafzelechin extracted from Cassia javanica inhibits herpes simplex virus type 2 replication

Cheng, HY, Yang, CM, Lin, TC, Shieh, DE, and Lin, CC

J Med Microbiol 2006. 55(Pt 2): 201-206


11. 58170 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Simple Synthesis and Anti-Hiv Activity of Novel Cyclopentene Phosphonate Nucleosides

Kim, A. and Hong, J.

Nucleosides Nucleotides & Nucleic Acids 2006. 25(1): 1-8


12. 58171 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Antiviral applications of RNAi for coronavirus

Wu, CJ and Chan, YL

Expert Opin Investig Drugs 2006. 15(2): 89-97


13. 58172 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses

Hayden, F, Klimov, A, Tashiro, M, Hay, A, Monto, A, McKimm-Breschkin, J, Macken, C, Hampson, A, Webster, RG, Amyard, M, and Zambon, M

Antivir Ther 2005. 10(8): 873-877


14. 58173 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Antiviral property and mechanisms of a sulphated polysaccharide from the brown alga Sargassum patens against Herpes simplex virus type 1

Zhu, W, Chiu, LC, Ooi, VE, Chan, PK, and Ang, PO Jr

Phytomedicine 2006.


15. 58174 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

Antiviral prodrugs - the development of successful prodrug strategies for antiviral chemotherapy

De Clercq, Erik and Field, Hugh J

British Journal of Pharmacology 2006. 147(1): 1-11

16. 58175 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

High levels of adamantane resistance among influenza A (H3N2) viruses and interim guidelines for use of antiviral agents--United States, 2005-06 influenza season


MMWR Morb Mortal Wkly Rep 2006. 55(2): 44-46


17. 58176 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

Palliser, Deborah, Chowdhury, Dipanjan, Wang, Qing-Yin, Lee, Sandra J, Bronson, Roderick T, Knipe, David M, and Lieberman, Judy

Nature (London, United Kingdom) 2006. 439(7072): 89-94

18. 58177 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Primary cytomegalovirus disease after five years of antiviral prophylaxis

Kijpittayarit, S, Deziel, P, Eid, AJ, and Razonable, RR

Transplantation 2006. 81(1): 137-138


19. 58178 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Synthesis and biological activity of isoxazolidinyl polycyclic aromatic hydrocarbons: potential DNA intercalators

Rescifina, A, Chiacchio, MA, Corsaro, A, De Clercq, E, Iannazzo, D, Mastino, A, Piperno, A, Romeo, G, Romeo, R, and Valveri, V

J Med Chem 2006. 49(2): 709-715


20. 58179 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Potent 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid-based macrocyclic inhibitors of hepatitis C virus NS3 protease

Chen, KX, Njoroge, FG, Pichardo, J, Prongay, A, Butkiewicz, N, Yao, N, Madison, V, and Girijavallabhan, V

J Med Chem 2006. 49(2): 567-574


21. 58180 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Cyanoacetic Acid Hydrazones of 3-(and 4-)Acetylpyridine and Some Derived Ring Systems as Potential Antitumor and Anti-HCV Agents

El-Hawash, SA, Abdel, Wahab AE, and El-Demellawy, MA

Arch Pharm (Weinheim) 2006. 339(1): 14-23


22. 58181 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

Imidazole and thiazole derivatives as antiviral agents

Conte, Immacolata, Hernando, Jose Ignacio Martin, Malancona, Savina, Ontoria Ontoria, Jesus Maria, and Stansfield, Ian

PATENT: WO 2006008556 ISSUE DATE: 20060126

APPLICATION: 2005 PP: 34 pp.

ASSIGNEE: (Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA, Italy

23. 58182 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

Use of a combination of cyclosporin and pegylated interferon for treating hepatitis C (HVC)

Cornu-Artis, Catherine, Vachon, Guylaine, Uryuhara, Yoko, Asakawa, Kazuo, Mertes, Reinhild Elisabeth, and Yoshiba, Shinsyou

PATENT: WO 2006005610 ISSUE DATE: 20060119

APPLICATION: 2005 PP: 13 pp.

ASSIGNEE: (Novartis A.-G., Switz. and Novartis Pharma G.m.b.H.)

24. 58183 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Construction of influenza virus siRNA expression vectors and their inhibitory effects on multiplication of influenza virus

Li, YC, Kong, LH, Cheng, BZ, and Li, KS

Avian Dis 2005. 49(4): 562-573


25. 58184 DMID-LS-111; SCIFINDER-DMID-1/31/2006 ; DMID-LSLOAD

Preparation of aza nucleoside analogs and their use as antiviral agents and inhibiting viral RNA polymerases

Babu, Yarlagadda S., Chand, Pooran, Ghosh, Ajit K., Kotian, Pravin L., and Kumar, Satish V

PATENT: WO 2006002231 ISSUE DATE: 20060105

APPLICATION: 2005 PP: 75 pp.

ASSIGNEE: (Biocryst Pharmaceuticals, Inc. USA

26. 58185 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Aminopyrimidinimino isatin analogues: design of novel non- nucleoside HIV-1 reverse transcriptase inhibitors with broad-spectrum chemotherapeutic properties

Sriram, D, Bal, TR, and Yogeeswari, P

J Pharm Pharm Sci 2005. 8(3): 565-577


27. 58186 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Neuraminidase Inhibitors and Their Potential Use in the Avian Influenza Pandemic

Reina, J.

Medicina Clinica 2005. 125(20): 780-783


28. 58187 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Effect of clarithromycin on rhinovirus-16 infection in A549 cells

Jang, YJ, Kwon, HJ, and Lee, BJ

Eur Respir J 2006. 27(1): 12-19


29. 58188 DMID-LS-111; PUBMED-DMID-1/31/2006 ; DMID-LSLOAD

Depeptidization efforts on P(3)-P(2)(') alpha-ketoamide inhibitors of HCV NS3-4A serine protease: Effect on HCV replicon activity

Bogen, SL, Ruan, S, Liu, R, Agrawal, S, Pichardo, J, Prongay, A, Baroudy, B, Saksena, AK, Girijavallabhan, V, and Njoroge, FG

Bioorg Med Chem Lett 2005.


30. 58189 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Bortezomib (Velcade (Tm)) and the Bcl-2 Inhibitor Ha14-1 Synergistically Stimulate Apoptosis in Ebv-Transformed Lymphocytes: a Potential Approach to Treatment of Ebv-Associated Lymphoproliferative Disorders.

Srimatkandada, P., Loomis, R., and Lacy, J.

Blood 2005. 106(11): 677A


31. 58190 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Antiviral Response in Pandemic Influenza Viruses

Garcia-Sastre, A.

Emerging Infectious Diseases 2006. 12(1): 44-47


32. 58191 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Pandemic Influenza Threat and Preparedness

Fauci, A.

Emerging Infectious Diseases 2006. 12(1): 73-77


33. 58192 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Economics of Neuraminidase Inhibitor Stockpiling for Pandemic Influenza, Singapore

Lee, V. et al.

Emerging Infectious Diseases 2006. 12(1): 95-102


34. 58193 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Design, Synthesis, and Antiviral Evaluation of Some Polyhalogenated Indole C-Nucleosides

Chen, J. et al.

Nucleosides Nucleotides & Nucleic Acids 2005. 24(10-12): 1417-1437


35. 58194 DMID-LS-111; WOS-DMID-1/31/2006 ; DMID-LSLOAD

Ribavarin Should Be Tested in Clinical Trials in Combination With Other Antiviral Agents for Severe Acute Respiratory Syndrome

Chu, C. and Chan, K.

Chest 2005. 128(6): 4050


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