NIAID Banner Logo Image


1. 58308 DMID-LS-116; EMBASE-DMID-4/12/2006 ; DMID-LSLOAD

A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity

Fan, Xuesen, Zhang, Xinying, Zhou, Longhu, Keith, Kathy A, Kern, Earl R, and Torrence, Paul F

Bioorganic & Medicinal Chemistry Letters 2006. In Press, Corrected Proof


2. 58309 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Antiviral compounds and one new iridoid glycoside from Cornus officinalis

Wang, Y, Li, ZQ, Chen, LR, and Xu, XJ

PROGRESS IN NATURAL SCIENCE: Prog. Nat. Sci 2006. 16(2): 142-146, 5


3. 58310 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Recent advances in anti-influenza agents with neuraminidase as target

Zhang, H and Xu, WF

MINI-REVIEWS IN MEDICINAL CHEMISTRY: Mini-Rev. Med. Chem 2006. 6(4): 429-448, 20


4. 58311 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon

Shimakami, T, Honda, M, Kusakawa, T, Murata, T, Shimotohno, K, Kaneko, S, and Murakami, S

JOURNAL OF VIROLOGY: J. Virol 2006. 80(7): 3332-3340, 9


5. 58312 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Brd4 is involved in multiple processes of the bovine papillomavirus type 1 life cycle

Ilves, I, Maemets, K, Silla, T, Janikson, K, and Ustav, M

JOURNAL OF VIROLOGY: J. Virol 2006. 80(7): 3660-3665, 6


6. 58313 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Recovery of a neurovirulent human coronavirus OC43 from an infectious cDNA clone

St-Jean, JR, Desforges, M, Almazan, F, Jacomy, H, Enjuanes, L, and Talbot, PJ

JOURNAL OF VIROLOGY: J. Virol 2006. 80(7): 3670-3674, 5


7. 58314 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Nucleic-acid-based antiviral agents against positive single-stranded RNA viruses

Lim, TW, Yuan, J, Liu, Z, Qiu, DX, Sall, A, and Yang, DC

CURRENT OPINION IN MOLECULAR THERAPEUTICS: Curr. Opin. Mol. Ther 2006. 8(2): 104-107, 4


8. 58315 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Oligonucleotide analogs as antiviral agents

Fabani, MM, Turner, JJ, and Gait, MJ

CURRENT OPINION IN MOLECULAR THERAPEUTICS: Curr. Opin. Mol. Ther 2006. 8(2): 108-114, 7


9. 58316 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

Evans, KA, Chai, DP, Graybill, TL, Burton, G, Sarisky, RT, Lin-Goerke, J, Johnston, VK, and Rivero, RA

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS: Bioorg. Med. Chem. Lett 2006. 16(8): 2205-2208, 4


10. 58317 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Prospects and strategies for the discovery and development of small-molecule inhibitors of six-helix bundle formation in class 1 viral fusion proteins

Debnath, AK

CURRENT OPINION IN INVESTIGATIONAL DRUGS: Curr. Opin. Investig. Drugs 2006. 7(2): 118-127, 10


11. 58318 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Potential applications of siRNA in hepatitis C virus therapy

Smolic, R, Volarevic, M, Wu, CH, and Wu, GY

CURRENT OPINION IN INVESTIGATIONAL DRUGS: Curr. Opin. Investig. Drugs 2006. 7(2): 142-146, 5


12. 58319 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

SCV-07 - SciClone pharmaceuticals/verta

Aspinall, RJ and Pockros, PJ

CURRENT OPINION IN INVESTIGATIONAL DRUGS: Curr. Opin. Investig. Drugs 2006. 7(2): 180-185, 6


13. 58320 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Therapeutic potential of an adenovirus expressing p73 beta, a p53 homologue, against human papilloma virus positive cervical cancer in vitro and in vivo

Das, S and Somasundaram, K

CANCER BIOLOGY & THERAPY: Cancer Biol. Ther 2006. 5(2): 210-217, 8


14. 58321 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus

Davis, IC, Lazarowski, ER, Hickman-Davis, JM, Fortenberry, JA, Chen, FP, Zhao, XD, Sorscher, E, Graves, LM, Sullender, WM, and Matalon, S

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE: Am. J. Respir. Crit. Care Med 2006. 173(6): 673-682, 10


15. 58322 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly

Stray, SJ, Johnson, JM, Kopek, BG, and Zlotnick, A

NATURE BIOTECHNOLOGY: Nat. Biotechnol 2006. 24(3): 358-362, 5


16. 58323 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Targeted delivery of ribavirin improves outcome of murine viral fulminant hepatitis via enhanced anti-viral activity

Levy, GA, Adamson, G, Phillips, MJ, Scrocchi, LA, Fung, L, Biessels, P, Ng, NF, Ghanekar, A, Rowe, A, Ma, MXZ, Levy, A, Koscik, C, He, W, Gorczynski, R, Brookes, S, Woods, C, McGilvray, ID, and Bell, D

HEPATOLOGY: Hepatology 2006. 43(3): 581-591, 11


17. 58324 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141

Cheng, YQ

CHEMBIOCHEM: ChemBioChem 2006. 7(3): 471-477, 7


18. 58325 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice

Enterlein, S, Warfield, KL, Swenson, DL, Stein, DA, Smith, JL, Gamble, CS, Kroeker, AD, Iversen, PL, Bavari, S, and Muhlberger, E

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY: Antimicrob. Agents Chemother 2006. 50( 3): 984-993, 10


19. 58326 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD

SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells

Malcolm, BA, Liu, R, Lahser, F, Agrawal, S, Belanger, B, Butkiewicz, N, Chase, R, Gheyas, F, Hart, A, Hesk, D, Ingravallo, P, Jiang, C, Kong, R, Lu, J, Pichardo, J, Prongay, A, Skelton, A, Tong, X, Venkatraman, S, Xia, E, Girijavallabhan, V, and Njoroge, FG

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY: Antimicrob. Agents Chemother 2006. 50( 3): 1013-1020, 8


20. 58327 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Potential antivirals and antiviral strategies against SARS coronavirus infections

De Clercq, E

Expert Rev Anti Infect Ther 2006. 4(2): 291-302


21. 58328 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Smallpox antiviral drug development: satisfying the animal efficacy rule

Jordan, R and Hruby, D

Expert Rev Anti Infect Ther 2006. 4(2): 277-89


22. 58329 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Oligonucleotide-based antiviral strategies

Schubert, S and Kurreck, J

Handb Exp Pharmacol 2006.(173): 261-87


23. 58330 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Synthesis of Non-Nucleosides: 7- and 1,3-Substituents of New Pyrrolo[2,3-d]pyrimidin-4-ones on Antiviral Activity

Hilmy, KM

Arch Pharm (Weinheim) 2006. 339(4): 174-181


24. 58331 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Pandemic influenza: using evidence on vaccines and antivirals for clinical decisions and policy making

Granados, A, Goodman, C, and Eklund, L

Eur Respir J 2006. 27(4): 661-3


25. 58332 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase

Mann, MC, Islam, T, Dyason, JC, Florio, P, Trower, CJ, Thomson, RJ, and Itzstein, M

Glycoconj J 2006. 23(1-2): 127-33


26. 58333 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target

Twu, KY, Noah, DL, Rao, P, Kuo, RL, and Krug, RM

J Virol 2006. 80(8): 3957-65


27. 58334 DMID-LS-116; LR-14931-LWC; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

1,4-benzodiazepines as inhibitors of respiratory syncytial virus

Carter, MC, Alber, DG, Baxter, RC, Bithell, SK, Budworth, J, Chubb, A, Cockerill, GS, Dowdell, VC, Henderson, EA, Keegan, SJ, Kelsey, RD, Lockyer, MJ, Stables, JN, Wilson, LJ, and Powell, KL

J Med Chem 2006. 49(7): 2311-2319


28. 58335 DMID-LS-116; PUBMED-DMID-4/10/2006; LR-14642 ; DMID-LSLOAD

Ether Lipid Ester Derivatives of Cidofovir Inhibit Polyomavirus BK Replication In Vitro

Randhawa, P, Farasati, NA, Shapiro, R, and Hostetler, KY

Antimicrob Agents Chemother 2006. 50(4): 1564-1566


29. 58336 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection

Malakhov, MP, Aschenbrenner, LM, Smee, DF, Wandersee, MK, Sidwell, RW, Gubareva, LV, Mishin, VP, Hayden, FG, Kim, do H, Ing, A, Campbell, ER, Yu, M, and Fang, F

Antimicrob Agents Chemother 2006. 50(4): 1470-9


30. 58337 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Activity and Mechanism of Action of N-Methanocarbathymidine against Herpesvirus and Orthopoxvirus Infections

Prichard, MN, Keith, KA, Quenelle, DC, and Kern, ER

Antimicrob Agents Chemother 2006. 50(4): 1336-41


31. 58338 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Inhibition of hepatitis C virus RNA replication by short hairpin RNA synthesized by T7 RNA polymerase in hepatitis C virus subgenomic replicons

Hamazaki, H, Ujino, S, Miyano-Kurosaki, N, Shimotohno, K, and Takaku, H

Biochem Biophys Res Commun 2006. 343(3): 988-94


32. 58339 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811

Goto, K, Watashi, K, Murata, T, Hishiki, T, Hijikata, M, and Shimotohno, K

Biochem Biophys Res Commun 2006. 343(3): 879-884


33. 58340 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Inhibitory efficacy of cyclosal-nucleoside monophosphates of aciclovir and brivudin on DNA synthesis of orthopoxvi ruses

Sauerbrei, A, Meier, C, Meerbach, A, and Wutzler, P

Antivir Chem Chemother 2006. 17(1): 25-31


34. 58341 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture

Balzarini, J, Celen, S, Karlsson, A, de Groot, T, Verbruggen, A, and Bormans, G

Antivir Chem Chemother 2006. 17(1): 17-23


35. 58342 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Evaluation of synthetic oligonucleotides as inhibitors of West Nile virus replication

Torrence, PF, Gupta, N, Whitney, C, and Morrey, JD

Antiviral Res 2006.


36. 58343 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Developments in antiviral drug design, discovery and development in 2004

Meanwell, NA, Belema, M, Carini, DJ, D'Andrea, SV, Kadow, JF, Krystal, M, Naidu, BN, Regueiro-Ren, A, Scola, PM, Sit, SY, Walker, MA, Wang, T, and Yeung, KS

Curr Drug Targets Infect Disord 2005. 5(4): 307-400


37. 58344 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

Erbel, P, Schiering, N, D'Arcy, A, Renatus, M, Kroemer, M, Lim, SP, Yin, Z, Keller, TH, Vasudevan, SG, and Hommel, U

Nat Struct Mol Biol 2006.


38. 58345 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD

Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs

Prichard, MN, Williams, AD, Keith, KA, Harden, EA, and Kern, ER

Antiviral Res 2006.


If using ChemDB information for publication or abstract presentation, please cite the website in addition to the original information source.    Database last updated: May 2024