ONLINE DATABASE SEARCH - DMID-LS-116-MEMO
1. 58308 DMID-LS-116; EMBASE-DMID-4/12/2006 ; DMID-LSLOAD
A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity
Fan, Xuesen, Zhang, Xinying, Zhou, Longhu, Keith, Kathy A, Kern, Earl R, and Torrence, Paul F
Bioorganic & Medicinal Chemistry Letters 2006. In Press, Corrected Proof
HYPERLINK:
http://www.sciencedirect.com/science/article/B6TF9-4JN2NRM-4/2/ad734ab55baf9d8b258f1998c2dbc564
2. 58309 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Antiviral compounds and one new iridoid glycoside from Cornus officinalis
Wang, Y, Li, ZQ, Chen, LR, and Xu, XJ
PROGRESS IN NATURAL SCIENCE: Prog. Nat. Sci 2006. 16(2): 142-146, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236287000005
3. 58310 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Recent advances in anti-influenza agents with neuraminidase as target
Zhang, H and Xu, WF
MINI-REVIEWS IN MEDICINAL CHEMISTRY: Mini-Rev. Med. Chem 2006. 6(4): 429-448, 20
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236267700008
4. 58311 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon
Shimakami, T, Honda, M, Kusakawa, T, Murata, T, Shimotohno, K, Kaneko, S, and Murakami, S
JOURNAL OF VIROLOGY: J. Virol 2006. 80(7): 3332-3340, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236305200020
5. 58312 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Brd4 is involved in multiple processes of the bovine papillomavirus type 1 life cycle
Ilves, I, Maemets, K, Silla, T, Janikson, K, and Ustav, M
JOURNAL OF VIROLOGY: J. Virol 2006. 80(7): 3660-3665, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236305200055
6. 58313 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Recovery of a neurovirulent human coronavirus OC43 from an infectious cDNA clone
St-Jean, JR, Desforges, M, Almazan, F, Jacomy, H, Enjuanes, L, and Talbot, PJ
JOURNAL OF VIROLOGY: J. Virol 2006. 80(7): 3670-3674, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236305200057
7. 58314 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Nucleic-acid-based antiviral agents against positive single-stranded RNA viruses
Lim, TW, Yuan, J, Liu, Z, Qiu, DX, Sall, A, and Yang, DC
CURRENT OPINION IN MOLECULAR THERAPEUTICS: Curr. Opin. Mol. Ther 2006. 8(2): 104-107, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236285300003
8. 58315 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Oligonucleotide analogs as antiviral agents
Fabani, MM, Turner, JJ, and Gait, MJ
CURRENT OPINION IN MOLECULAR THERAPEUTICS: Curr. Opin. Mol. Ther 2006. 8(2): 108-114, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236285300004
9. 58316 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase
Evans, KA, Chai, DP, Graybill, TL, Burton, G, Sarisky, RT, Lin-Goerke, J, Johnston, VK, and Rivero, RA
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS: Bioorg. Med. Chem. Lett 2006. 16(8): 2205-2208, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236319000030
10. 58317 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Prospects and strategies for the discovery and development of small-molecule inhibitors of six-helix bundle formation in class 1 viral fusion proteins
Debnath, AK
CURRENT OPINION IN INVESTIGATIONAL DRUGS: Curr. Opin. Investig. Drugs 2006. 7(2): 118-127, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236125800003
11. 58318 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Potential applications of siRNA in hepatitis C virus therapy
Smolic, R, Volarevic, M, Wu, CH, and Wu, GY
CURRENT OPINION IN INVESTIGATIONAL DRUGS: Curr. Opin. Investig. Drugs 2006. 7(2): 142-146, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236125800006
12. 58319 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
SCV-07 - SciClone pharmaceuticals/verta
Aspinall, RJ and Pockros, PJ
CURRENT OPINION IN INVESTIGATIONAL DRUGS: Curr. Opin. Investig. Drugs 2006. 7(2): 180-185, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236125800011
13. 58320 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Therapeutic potential of an adenovirus expressing p73 beta, a p53 homologue, against human papilloma virus positive cervical cancer in vitro and in vivo
Das, S and Somasundaram, K
CANCER BIOLOGY & THERAPY: Cancer Biol. Ther 2006. 5(2): 210-217, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236044600022
14. 58321 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus
Davis, IC, Lazarowski, ER, Hickman-Davis, JM, Fortenberry, JA, Chen, FP, Zhao, XD, Sorscher, E, Graves, LM, Sullender, WM, and Matalon, S
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE: Am. J. Respir. Crit. Care Med 2006. 173(6): 673-682, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000236182100015
15. 58322 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly
Stray, SJ, Johnson, JM, Kopek, BG, and Zlotnick, A
NATURE BIOTECHNOLOGY: Nat. Biotechnol 2006. 24(3): 358-362, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235868600040
16. 58323 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Targeted delivery of ribavirin improves outcome of murine viral fulminant hepatitis via enhanced anti-viral activity
Levy, GA, Adamson, G, Phillips, MJ, Scrocchi, LA, Fung, L, Biessels, P, Ng, NF, Ghanekar, A, Rowe, A, Ma, MXZ, Levy, A, Koscik, C, He, W, Gorczynski, R, Brookes, S, Woods, C, McGilvray, ID, and Bell, D
HEPATOLOGY: Hepatology 2006. 43(3): 581-591, 11
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235911200026
17. 58324 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141
Cheng, YQ
CHEMBIOCHEM: ChemBioChem 2006. 7(3): 471-477, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235930800012
18. 58325 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice
Enterlein, S, Warfield, KL, Swenson, DL, Stein, DA, Smith, JL, Gamble, CS, Kroeker, AD, Iversen, PL, Bavari, S, and Muhlberger, E
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY: Antimicrob. Agents Chemother 2006. 50( 3): 984-993, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235786300023
19. 58326 DMID-LS-116; WOS-DMID-4/10/2006 ; DMID-LSLOAD
SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells
Malcolm, BA, Liu, R, Lahser, F, Agrawal, S, Belanger, B, Butkiewicz, N, Chase, R, Gheyas, F, Hart, A, Hesk, D, Ingravallo, P, Jiang, C, Kong, R, Lu, J, Pichardo, J, Prongay, A, Skelton, A, Tong, X, Venkatraman, S, Xia, E, Girijavallabhan, V, and Njoroge, FG
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY: Antimicrob. Agents Chemother 2006. 50( 3): 1013-1020, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235786300026
20. 58327 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Potential antivirals and antiviral strategies against SARS coronavirus infections
De Clercq, E
Expert Rev Anti Infect Ther 2006. 4(2): 291-302
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16597209&dopt=abstract
21. 58328 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Smallpox antiviral drug development: satisfying the animal efficacy rule
Jordan, R and Hruby, D
Expert Rev Anti Infect Ther 2006. 4(2): 277-89
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16597208&dopt=abstract
22. 58329 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Oligonucleotide-based antiviral strategies
Schubert, S and Kurreck, J
Handb Exp Pharmacol 2006.(173): 261-87
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16594620&dopt=abstract
23. 58330 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Synthesis of Non-Nucleosides: 7- and 1,3-Substituents of New Pyrrolo[2,3-d]pyrimidin-4-ones on Antiviral Activity
Hilmy, KM
Arch Pharm (Weinheim) 2006. 339(4): 174-181
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16586425&dopt=abstract
24. 58331 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Pandemic influenza: using evidence on vaccines and antivirals for clinical decisions and policy making
Granados, A, Goodman, C, and Eklund, L
Eur Respir J 2006. 27(4): 661-3
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16585070&dopt=abstract
25. 58332 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase
Mann, MC, Islam, T, Dyason, JC, Florio, P, Trower, CJ, Thomson, RJ, and Itzstein, M
Glycoconj J 2006. 23(1-2): 127-33
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16575530&dopt=abstract
26. 58333 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target
Twu, KY, Noah, DL, Rao, P, Kuo, RL, and Krug, RM
J Virol 2006. 80(8): 3957-65
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16571812&dopt=abstract
27. 58334 DMID-LS-116; LR-14931-LWC; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
1,4-benzodiazepines as inhibitors of respiratory syncytial virus
Carter, MC, Alber, DG, Baxter, RC, Bithell, SK, Budworth, J, Chubb, A, Cockerill, GS, Dowdell, VC, Henderson, EA, Keegan, SJ, Kelsey, RD, Lockyer, MJ, Stables, JN, Wilson, LJ, and Powell, KL
J Med Chem 2006. 49(7): 2311-2319
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16570927&dopt=abstract
28. 58335 DMID-LS-116; PUBMED-DMID-4/10/2006; LR-14642 ; DMID-LSLOAD
Ether Lipid Ester Derivatives of Cidofovir Inhibit Polyomavirus BK Replication In Vitro
Randhawa, P, Farasati, NA, Shapiro, R, and Hostetler, KY
Antimicrob Agents Chemother 2006. 50(4): 1564-1566
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16569886&dopt=abstract
29. 58336 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection
Malakhov, MP, Aschenbrenner, LM, Smee, DF, Wandersee, MK, Sidwell, RW, Gubareva, LV, Mishin, VP, Hayden, FG, Kim, do H, Ing, A, Campbell, ER, Yu, M, and Fang, F
Antimicrob Agents Chemother 2006. 50(4): 1470-9
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16569867&dopt=abstract
30. 58337 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Activity and Mechanism of Action of N-Methanocarbathymidine against Herpesvirus and Orthopoxvirus Infections
Prichard, MN, Keith, KA, Quenelle, DC, and Kern, ER
Antimicrob Agents Chemother 2006. 50(4): 1336-41
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16569849&dopt=abstract
31. 58338 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Inhibition of hepatitis C virus RNA replication by short hairpin RNA synthesized by T7 RNA polymerase in hepatitis C virus subgenomic replicons
Hamazaki, H, Ujino, S, Miyano-Kurosaki, N, Shimotohno, K, and Takaku, H
Biochem Biophys Res Commun 2006. 343(3): 988-94
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16566896&dopt=abstract
32. 58339 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811
Goto, K, Watashi, K, Murata, T, Hishiki, T, Hijikata, M, and Shimotohno, K
Biochem Biophys Res Commun 2006. 343(3): 879-884
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16564500&dopt=abstract
33. 58340 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Inhibitory efficacy of cyclosal-nucleoside monophosphates of aciclovir and brivudin on DNA synthesis of orthopoxvi ruses
Sauerbrei, A, Meier, C, Meerbach, A, and Wutzler, P
Antivir Chem Chemother 2006. 17(1): 25-31
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16542003&dopt=abstract
34. 58341 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture
Balzarini, J, Celen, S, Karlsson, A, de Groot, T, Verbruggen, A, and Bormans, G
Antivir Chem Chemother 2006. 17(1): 17-23
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16542002&dopt=abstract
35. 58342 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Evaluation of synthetic oligonucleotides as inhibitors of West Nile virus replication
Torrence, PF, Gupta, N, Whitney, C, and Morrey, JD
Antiviral Res 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16540182&dopt=abstract
36. 58343 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Developments in antiviral drug design, discovery and development in 2004
Meanwell, NA, Belema, M, Carini, DJ, D'Andrea, SV, Kadow, JF, Krystal, M, Naidu, BN, Regueiro-Ren, A, Scola, PM, Sit, SY, Walker, MA, Wang, T, and Yeung, KS
Curr Drug Targets Infect Disord 2005. 5(4): 307-400
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16535860&dopt=abstract
37. 58344 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus
Erbel, P, Schiering, N, D'Arcy, A, Renatus, M, Kroemer, M, Lim, SP, Yin, Z, Keller, TH, Vasudevan, SG, and Hommel, U
Nat Struct Mol Biol 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16532006&dopt=abstract
38. 58345 DMID-LS-116; PUBMED-DMID-4/10/2006 ; DMID-LSLOAD
Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs
Prichard, MN, Williams, AD, Keith, KA, Harden, EA, and Kern, ER
Antiviral Res 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16530858&dopt=abstract