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1. 59108 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Benzo[2,3]azepino[4,5-b]indol-6-ones as kinase or phosphatase inhibitors, their preparation, pharmaceutical compositions, and use against infectious diseases

Klebl, Bert, Neumann, Lars, Hafenbradl, Doris, Greff, Zoltan, Keri, Gyoergy, and Oerfi, Laszlo

PATENT: WO 2006089874 ISSUE DATE: 20060831

APPLICATION: 2006 PP: 67pp.

ASSIGNEE: (Gpc Biotech AG, Germany

2. 59109 DMID-LS-129; PUBMED-DMID-10/9/2006

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

Okamoto, T, Nishimura, Y, Ichimura, T, Suzuki, K, Miyamura, T, Suzuki, T, Moriishi, K, and Matsuura, Y

EMBO J 2006.


3. 59110 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Polysaccharide-oligoamine conjugates as anti-amyloid and anti-viral agents

Domb, Abraham J, Katz, Ehud, Yudovin-Farber, Ira, and Taraboulos, Albert

PATENT: WO 2006090365 ISSUE DATE: 20060831

APPLICATION: 2006 PP: 44pp.

ASSIGNEE: (Yissum Research Development Company, Israel

4. 59111 DMID-LS-129; PUBMED-DMID-10/9/2006

A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

Imbert, I, Guillemot, JC, Bourhis, JM, Bussetta, C, Coutard, B, Egloff, MP, Ferron, F, Gorbalenya, AE, and Canard, B

EMBO J 2006.


5. 59112 DMID-LS-129; PUBMED-DMID-10/9/2006

Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors

Iqbal, J, Scapozza, L, Folkers, G, and Muller, CE

J Chromatogr B Analyt Technol Biomed Life Sci 2006.


6. 59113 DMID-LS-129; PUBMED-DMID-10/9/2006

Antiviral treatment of hepatitis C

Toniutto, P, Fabris, C, and Pirisi, M

Expert Opin Pharmacother 2006. 7(15): 2025-35


7. 59114 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Sulfur oligonucleotides having antiviral activities

Vaillant, Andrew and Juteau, Jean-Marc

PATENT: WO 2006096995 ISSUE DATE: 20060921

APPLICATION: 2006 PP: 51pp.

ASSIGNEE: (Replicor Inc., Can.

8. 59115 DMID-LS-129; PUBMED-DMID-10/9/2006

Modular alpha-Helical Mimetics with Antiviral Activity against Respiratory Syncitial Virus

Shepherd, NE, Hoang, HN, Desai, VS, Letouze, E, Young, PR, and Fairlie, DP

J Am Chem Soc 2006. 128(40): 13284-9


9. 59116 DMID-LS-129; PUBMED-DMID-10/9/2006

In Vitro Antiviral Activity of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose against Hepatitis B Virus

Lee, SJ, Lee, HK, Jung, MK, and Mar, W

Biol Pharm Bull 2006. 29(10): 2131-4


10. 59117 DMID-LS-129; PUBMED-DMID-10/9/2006

Glycan microarray technologies: tools to survey host specificity of influenza viruses

Stevens, J, Blixt, O, Paulson, JC, and Wilson, IA

Nat Rev Microbiol 2006.


11. 59118 DMID-LS-129; PUBMED-DMID-10/9/2006

Validation of biocides against duck hepatitis B virus as a surrogate virus for human hepatitis B virus

Sauerbrei, A, Schacke, M, Gluck, B, Egerer, R, and Wutzler, P

J Hosp Infect 2006.


12. 59119 DMID-LS-129; PUBMED-DMID-10/9/2006

Hepatitis C Virus RNA-Dependent RNA Polymerase: Study on the Inhibition Mechanism by Pyrogallol Derivatives

Kozlov, MV, Polyakov, KM, Ivanov, AV, Filippova, SE, Kuzyakin, AO, Tunitskaya, VL, and Kochetkov, SN

Biochemistry (Mosc) 2006. 71(9): 1021-6


13. 59120 DMID-LS-129; PUBMED-DMID-10/9/2006

Novel methods to treat and prevent human papillomavirus infection

Kendrick, JE, Huh, WK, and Alvarez, RD

Expert Rev Anti Infect Ther 2006. 4(4): 593-600


14. 59121 DMID-LS-129; PUBMED-DMID-10/9/2006

Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo

Korba, BE, Furman, PA, and Otto, MJ

Expert Rev Anti Infect Ther 2006. 4(4): 549-61


15. 59122 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Crimean-Congo Hemorrhagic Fever

Gunes Turabi

Mikrobiyoloji bulteni 2006. 40(3): 279-87.

16. 59123 DMID-LS-129; PUBMED-DMID-10/9/2006

Biological interactions between herpesviruses and cyclooxygenase enzymes

Reynolds, AE and Enquist, LW

Rev Med Virol 2006.


17. 59124 DMID-LS-129; PUBMED-DMID-10/9/2006

BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly

Stray, SJ and Zlotnick, A

J Mol Recognit 2006.


18. 59125 DMID-LS-129; PUBMED-DMID-10/9/2006

Maribavir antagonizes the antiviral action of ganciclovir on human cytomegalovirus

Chou, S and Marousek, GI

Antimicrob Agents Chemother 2006. 50(10): 3470-3472


19. 59126 DMID-LS-129; PUBMED-DMID-10/9/2006

Ribavirin antagonizes the in vitro anti-hepatitis C virus activity of 2'-C-methylcytidine, the active component of valopicitabine

Coelmont, L, Paeshuyse, J, Windisch, MP, De, Clercq E, Bartenschlager, R, and Neyts, J

Antimicrob Agents Chemother 2006. 50(10): 3444-6


20. 59127 DMID-LS-129; PUBMED-DMID-10/9/2006

Tyro3 family-mediated cell entry of ebola and marburg viruses

Shimojima, M, Takada, A, Ebihara, H, Neumann, G, Fujioka, K, Irimura, T, Jones, S, Feldmann, H, and Kawaoka, Y

J Virol 2006. 80(20): 10109-16


21. 59128 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Identification of two amino acid residues on Ebola virus glycoprotein 1 critical for cell entry

Mpanju, Onesmo M, Towner, Jonathan S, Dover, Jason E, Nichol, Stuart T, and Wilson, Carolyn A

Virus Research 2006. 121(2): 205-214

22. 59129 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Treatments for Flaviviridae virus infection

Malcolm, Bruce A, Palermo, Robert, Tong, Xiao, Feld, Boris, and Le, Hung

PATENT: US 2006198824 ISSUE DATE: 20060907

APPLICATION: 2006-37328 PP: 37pp.

ASSIGNEE: (Schering Corporation, USA

23. 59130 DMID-LS-129; PUBMED-DMID-10/9/2006

Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobuty l]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Venkatraman, S, Bogen, SL, Arasappan, A, Bennett, F, Chen, K, Jao, E, Liu, YT, Lovey, R, Hendrata, S, Huang, Y, Pan, W, Parekh, T, Pinto, P, Popov, V, Pike, R, Ruan, S, Santhanam, B, Vibulbhan, B, Wu, W, Yang, W, Kong, J, Liang, X, Wong, J, Liu, R, Butkiewicz, N, Chase, R, Hart, A, Agrawal, S, Ingravallo, P, Pichardo, J, Kong, R, Baroudy, B, Malcolm, B, Guo, Z, Prongay, A, Madison, V, Broske, L, Cui, X, Cheng, KC, Hsieh, Y, Brisson, JM, Prelusky, D, Korfmacher, W, White, R, Bogdanowich-Knipp, S, Pavlovsky, A, Bradley, P, Saksena, AK, Ganguly, A, Piwinski, J, Girijavallabhan, V, and Njoroge, FG

J Med Chem 2006. 49(20): 6074-86


24. 59131 DMID-LS-129; PUBMED-DMID-10/9/2006

Virtual screening for finding natural inhibitor against cathepsin-L for SARS therapy

Wang, SQ, Du, QS, Zhao, K, Li, AX, Wei, DQ, and Chou, KC

Amino Acids 2006.


25. 59132 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Preparation of b-polypeptides that inhibit cytomegalovirus infection

Compton, Teresa, Gellman, Samuel H, English, Emily P, and Chumanov, Robert S

PATENT: WO 2006099170 ISSUE DATE: 20060921

APPLICATION: 2006 PP: 69pp.

ASSIGNEE: (Wisconsin Alumni Research Foundation, USA

26. 59133 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Preparation of bisheterocyclic compounds as antiviral agents

Nan, Fajun, Zuo, Jianping, Wang, Wenlong, Wang, Guifeng, Chen, Haijun, and He, Peilan

PATENT: WO 2006097030 ISSUE DATE: 20060921

APPLICATION: 2006 PP: 71pp.

ASSIGNEE: (Shanghai Institute of Materia Medica , Chinese Academy of Sciences Peop. Rep. China

27. 59134 DMID-LS-129; SCIFINDER-DMID-10/9/2006

In vitro comparative experiments of aciclovir injectables, Acirovec injection and Zovirax for I.V. infusion, on anti-herpes virus activity

Ogura, Takeharu, Kataoka, Hirofumi, Ohtsubo, Yoshikazu, Ueda, Haruyasu, and Okamura, Haruki

Igaku to Yakugaku 2006. 55(6): 893-900

28. 59135 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Viral protein epitopes and antiviral agents for diagnosis, prognosis and treatment of antiviral agent-resistant HIV-1 and hepatitis B virus infection

Catanzaro, Andrew, Yarchoan, Robert, Berzofsky, Jay A, Okazaki, Takahiro, Snyder, James T II, and Broder, Samuel

PATENT: WO 2006091798 ISSUE DATE: 20060831

APPLICATION: 2006 PP: 103pp.

ASSIGNEE: (The Government of the United States of America, As Represented by the Secretary of the Department of Health and Human Services USA

29. 59136 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Preparation of imidazol-4-ylureas as antiviral agents

Zimmermann, Holger, Brueckner, David, Henninger, Kerstin, Rosentreter, Ulrich, Hendrix, Martin, Keldenich, Joerg, Lang, Dieter, Radtke, Martin, Paulsen, Daniela, and Kern, Armin

PATENT: WO 2006089664 ISSUE DATE: 20060831

APPLICATION: 2006 PP: 62pp.

ASSIGNEE: (Bayer Healthcare A.-G., Germany

30. 59137 DMID-LS-129; PUBMED-DMID-10/9/2006


Shi, D, Yang, J, Yang, D, Lecluyse, EL, Black, C, You, L, Akhlaghi, F, and Yan, B

J Pharmacol Exp Ther 2006.


31. 59138 DMID-LS-129; WOS-DMID-10/9/2006

A Luciferase-Based Budding Assay for Ebola Virus

Mccarthy, S., Licata, J., and Harty, R.

Journal of Virological Methods 2006. 137(1): 115-119


32. 59139 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Aryl furano pyrimidines: The most potent and selective anti-VZV agents reported to date

McGuigan, Christopher and Balzarini, Jan

Antiviral Research 2006. 71(2-3): 149-153

33. 59140 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Structure and Antiviral Activity of the Galactofucan Sulfates Extracted from Undaria Pinnatifida (Phaeophyta)

Hemmingson, JA, Falshaw, R, Furneaux, RH, and Thompson, K

Journal of Applied Phycology 2006. 18(2): 185-193

34. 59141 DMID-LS-129; WOS-DMID-10/9/2006

The Synthesis and Antiviral Properties of Acyclic Nucleoside Analogues With a Phosphonomethoxy Fragment in the Side Chain

Khandazhinskaya, A., Yasko, M., and Shirokova, E.

Current Medicinal Chemistry 2006. 13(24): 2953-2980


35. 59142 DMID-LS-129; WOS-DMID-10/9/2006

Improved Replicon Cellular Activity of Non-Nucleoside Allosteric Inhibitors of Hcvns5b Polymerase: From Benzimidazole to Indole Scaffolds

Beaulieu, P. et al.

Bioorganic & Medicinal Chemistry Letters 2006. 16(19): 4987-4993


36. 59143 DMID-LS-129; PUBMED-DMID-10/9/2006

The crystal structure of the Venezuelan equine encephalitis alphavirus nsP2 protease

Russo, AT, White, MA, and Watowich, SJ

Structure 2006. 14(9): 1449-58


37. 59144 DMID-LS-129; SCIFINDER-DMID-10/9/2006

The synergistic effect of IFN-a and IFN-g against HSV-2 replication in vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin

Petrera, Erina and Coto, Celia E

Virology Journal 2006. 3: No pp. given

38. 59145 DMID-LS-129; WOS-DMID-10/9/2006

Design and Synthesis of Dipeptidyl Glutaminyl Fluoromethylketones as Potent Sars-Cov Inhibitors

Zhang, H. et al.

Abstracts of Papers of the American Chemical Society 2006. 231


39. 59146 DMID-LS-129; SCIFINDER-DMID-10/9/2006

In vitro inhibitory effects of recombinant consensus interferon a on herpes simplex type 1 and type 2 viruses

Xu, Bing, Wang, Shu-qin, Li, Yu-huan, and Tao, Pei-zhen

Redai Yixue Zazhi 2006. 6(4): 397-399

40. 59147 DMID-LS-129; WOS-DMID-10/9/2006

Identification of Pyrazolo[3,4-D]Pyrimidines as Inhibitors of a Hepatitis C Virus Replicon System

Barnes, M. et al.

Abstracts of Papers of the American Chemical Society 2006. 231


41. 59148 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Preparation of nucleoside analogues with 6-membered carbon ring structure as antiviral agents

Lou, Hongxiang, Zhan, Tianrong, Ma, Yudao, and Fan, Peihong

PATENT: CN 1803819 ISSUE DATE: 20060719

APPLICATION: 1004-2184 PP: 18 pp.

ASSIGNEE: (Shandong University, Peop. Rep. China

42. 59149 DMID-LS-129; WOS-DMID-10/9/2006

Rational Design of Measles Virus Entry Inhibitors and Mechanisms of Viral Resistance

Prussia, A. et al.

Abstracts of Papers of the American Chemical Society 2006. 231


43. 59150 DMID-LS-129; WOS-DMID-10/9/2006

A New Triterpene and Anti-Hepatitis B Virus Active Compounds From Alisma Orientalis

Jiang, Z. et al.

Planta Medica 2006. 72(10): 951-954


44. 59151 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Preparation of 4-(1H-Indol-3-yl)-pyrimidin-2-ylamine Derivatives as Protein Kinase Inhibitors and Their Use in Therapy

Fischer, Peter Martin, Wang, Shudong, Meades, Christopher Keith, Andrews, Martin James Inglis, Gibson, Darren, and Duncan, Kenneth

PATENT: WO 2006075152 ISSUE DATE: 20060720

APPLICATION: 2006 PP: 88 pp.

ASSIGNEE: (Cyclacel Limited, UK

45. 59152 DMID-LS-129; WOS-DMID-10/9/2006

Efficacy of Antiviral Compounds in Human Herpesvirus-6-Infected Glial Cells

Akhyani, N. et al.

Journal of Neurovirology 2006. 12(4): 284-293


46. 59153 DMID-LS-129; WOS-DMID-10/9/2006

Protein Kinase Ck2: a Potential Target in the Development of Novel Therapeutics Against West Nile Virus

Ramanathan, M. et al.

Journal of Neurovirology 2006. 12: 69


47. 59154 DMID-LS-129; WOS-DMID-10/9/2006

Neuraminidase Inhibitors Prevent Influenza Infection in Patients After Contact With an Influenza Index Case

Behrens, T. and Ahrens, W.

European Journal of Epidemiology 2006. 21: 108-109


48. 59155 DMID-LS-129; WOS-DMID-10/9/2006

Three-Dimensional Culture Models for Human Viral Diseases and Antiviral Drug Development

Andrei, G.

Antiviral Research 2006. 71(2-3): 96-107


49. 59156 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Influenza and the pandemic threat

Lee, V J, Fernandez, G G, Chen M I, Lye, D, and Leo, Y S

Singapore medical journal 2006. 47(6): 463-470

50. 59157 DMID-LS-129; WOS-DMID-10/9/2006

Ribonucleotide Reductase Inhibitors as Anti-Herpes Agents

Wnuk, S. and Robins, M.

Antiviral Research 2006. 71(2-3): 122-126


51. 59158 DMID-LS-129; WOS-DMID-10/9/2006

Tricyclic Nucleoside Analogues as Antiherpes Agents

Golankiewicz, B. and Ostrowski, T.

Antiviral Research 2006. 71(2-3): 134-140


52. 59159 DMID-LS-129; WOS-DMID-10/9/2006

Papillomavirus and Treatment

Snoeck, R.

Antiviral Research 2006. 71(2-3): 181-191


53. 59160 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Antiviral drug discovery targeting to viral proteases

Hsu John T A, Wang Hsiang-Ching, Chen Guang-Wu, and Shih Shin-Ru

Current pharmaceutical design 2006. 12(11): 1301-14.

54. 59161 DMID-LS-129; WOS-DMID-10/9/2006

New Developments in the Treatment of Chronic Hepatitis B

Hadziyannis, S.

Expert Opinion on Biological Therapy 2006. 6(9): 913-921


55. 59162 DMID-LS-129; SCIFINDER-DMID-10/9/2006

Preparation of peptides as coronavirus inhibitors

Kania, Robert Steven, Mitchell, Lennert Joseph Jr, and Nieman, James A

PATENT: WO 2006061714 ISSUE DATE: 20060615

APPLICATION: 2005 PP: 43 pp.

ASSIGNEE: (Pfizer Inc., USA

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