ONLINE DATABASE SEARCH - DMID-LS-131-MEMO
1. 59321 DMID-LS-131; PUBMED-DMID-11/7/2006
Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides
Rao, JR, Schinazi, RF, and Chu, CK
Bioorg Med Chem 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17085053&dopt=abstract
2. 59322 DMID-LS-131; PUBMED-DMID-11/7/2006
Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: From anti-pestivirus to anti-hepatitis C virus activity
Puerstinger, G, Paeshuyse, J, De, Clercq E, and Neyts, J
Bioorg Med Chem Lett 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17084081&dopt=abstract
3. 59323 DMID-LS-131; PUBMED-DMID-11/7/2006
Fluoro-ketopyranosyl nucleosides: Synthesis and biological evaluation of 3-fluoro-2-keto-beta-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine
Manta, S, Agelis, G, Botic, T, Cencic, A, and Komiotis, D
Bioorg Med Chem 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17079149&dopt=abstract
4. 59324 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Antiviral drug combinations using a glycosylation modulator and a membrane fusion inhibitor
Nash, Robert James, Slingsby, Jason H, and Carroll, Miles William
PATENT: WO 2006077427 ISSUE DATE: 20060727
APPLICATION: 2006 PP: 85 pp.
ASSIGNEE: (MNL Pharma Limited, UK
5. 59325 DMID-LS-131; PUBMED-DMID-11/7/2006
New therapeutic options for hepatitis C
Waters, L and Nelson, M
Curr Opin Infect Dis 2006. 19(6): 615-22
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17075339&dopt=abstract
6. 59326 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Thienyl compounds for treating virus-related conditions
Olivo, Paul D, Buscher, Benjamin A, Dyall, Julie, Jockel-Balsarotti, Jennifer I, O'Guin, Andrew K, Roth, Robert M, Franklin, Gary W, and Starkey, Gale W
PATENT: WO 2006093518 ISSUE DATE: 20060908
APPLICATION: 2005 PP: 343pp.
ASSIGNEE: (Apath, LLC USA
7. 59327 DMID-LS-131; PUBMED-DMID-11/7/2006
Activities of oseltamivir and ribavirin used alone and in combination against infections in mice with recent isolates of influenza A (H1N1) and B viruses
Smee, DF, Wong, MH, Bailey, KW, and Sidwell, RW
Antivir Chem Chemother 2006. 17(4): 185-192
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17066897&dopt=abstract
8. 59328 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Inhibitors of enveloped virus infectivity
Cunningham, James and Chandran, Kartik
PATENT: WO 2006091610 ISSUE DATE: 20060831
APPLICATION: 2006 PP: 65pp.
ASSIGNEE: (The Brigham and Women's Hospital, Inc. USA
9. 59329 DMID-LS-131; PUBMED-DMID-11/7/2006
Peptide Inhibitors of West Nile NS3 Protease: SAR Study of Tetrapeptide Aldehyde Inhibitors
Knox, JE, Ma, NL, Yin, Z, Patel, SJ, Wang, WL, Chan, WL, Ranga, Rao KR, Wang, G, Ngew, X, Patel, V, Beer, D, Lim, SP, Vasudevan, SG, and Keller, TH
J Med Chem 2006. 49(22): 6585-90
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17064076&dopt=abstract
10. 59330 DMID-LS-131; PUBMED-DMID-11/7/2006
Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design
El Omari, K, Solaroli, N, Karlsson, A, Balzarini, J, and Stammers, DK
BMC Struct Biol 2006. 6(1): 22
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17062140&dopt=abstract
11. 59331 DMID-LS-131; PUBMED-DMID-11/7/2006
Antiviral activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of inosine monophosphate dehydrogenase
Sun, Y, Chung, DH, Chu, YK, Jonsson, CB, and Parker, WB
Antimicrob Agents Chemother 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17060520&dopt=abstract
12. 59332 DMID-LS-131; PUBMED-DMID-11/7/2006
Synthesis and antiviral activity against tobacco mosaic virus and 3D-QSAR of alpha-substituted-1,2,3-thiadiazoleacetamides
Zhao, WG, Wang, JG, Li, ZM, and Yang, Z
Bioorg Med Chem Lett 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17055269&dopt=abstract
13. 59333 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of tricyclic nucleoside prodrugs for treating viral infections
Keicher, Jesse Daniel and Roberts, Christopher Don
PATENT: US 2006194749 ISSUE DATE: 20060831
APPLICATION: 2006-37490 PP: 63pp.
ASSIGNEE: (Genelabs Technologies, Inc. USA
14. 59334 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of heteroarylindolecarboxylates as antivirals
Botyanszki, Janos, Roberts, Christopher Don, Schmitz, Franz Ulrich, Gralapp, Joshua Michael, Griffith, Ronald Conrad, Shi, Dong-Fang, Leivers, Martin Robert, and Brewster, Rachel Elizabeth
PATENT: WO 2006076529 ISSUE DATE: 20060720
APPLICATION: 2006 PP: 203 pp.
ASSIGNEE: (Genelabs Technologies, Inc. USA
15. 59335 DMID-LS-131; WOS-DMID-11/7/2006
Potent Inhibition of Human Hepatitis B Virus Replication by a Host Factor Vps4
Chua, P., Lin, M., and Shih, C.
Virology 2006. 354(1): 1-6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241178500001
16. 59336 DMID-LS-131; PUBMED-DMID-11/7/2006
Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster model
Julander, JG, Morrey, JD, Blatt, LM, Shafer, K, and Sidwell, RW
Antiviral Res 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17049380&dopt=abstract
17. 59337 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Diketo acids on nucleobase scaffolds as inhibitors of Flaviviridae
Nair, Vasu, Chi, Guochen, and Uchil, Vinod R
PATENT: US 2006223834 ISSUE DATE: 20061005
APPLICATION: 2005-32589 PP: 36pp.
ASSIGNEE: (USA)
18. 59338 DMID-LS-131; WOS-DMID-11/7/2006
Substituted 5-Benzyl-2-Phenyl-5h-Imidazo[4,5-C]Pyridines: a New Class of Pestivirus Inhibitors
Puerstinger, G. et al.
Bioorganic & Medicinal Chemistry Letters 2006. 16(20): 5345-5349
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241344400019
19. 59339 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Medicine composition containing thymopentin and interferon as antiviral and antitumor agents
Wang, Shujuan, Jia, Zhidan, Piao, Zhisong, and Wang, Zhenguo
PATENT: CN 1833721 ISSUE DATE: 20060920
APPLICATION: 1007-6271 PP: 8pp.
ASSIGNEE: (Beijing Guodan Medicine Technological Development Co., Ltd. Peop. Rep. China and Jilin Yixin Pharmaceutical Co., Ltd.
20. 59340 DMID-LS-131; WOS-DMID-11/7/2006
Structure-Guided Design of a Novel Class of Benzyl-Sulfonate Inhibitors for Influenza Virus Neuraminidase
Platis, D. et al.
Biochemical Journal 2006. 399: 215-223
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241348600005
21. 59341 DMID-LS-131; WOS-DMID-11/7/2006
A Simple and Efficient Synthesis of 2-Deoxy-L-Ribose From 2-Deoxy-D-Ribose
Ji, Q. et al.
Synlett 2006.(15): 2498-2500
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241175500034
22. 59342 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Drug compositions containing tetrahydro-2H-thiopyran-4-carboxamide derivatives, and anti-herpesvirus agent containing the same
Kontani, Toru, Miyata, Junji, Hamaguchi, Wataru, Kamikawa, Akio, Kono, Tomoaki, Suzuki, Hiroshi, and Sudo, Kenji
PATENT: JP 2006241144 ISSUE DATE: 20060914
APPLICATION: 2006-24024 PP: 21pp.
ASSIGNEE: (Astellas Pharma Inc., Japan and Soyaku Gijutsu Kenkyusho K. K.)
23. 59343 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Curative-prophylactic pomade eliciting antiviral activity
Prokop'eva, LA, Vinogradov, AK, Kungurtseva, NV, Lesnykh, OA, Mitrofanova, EG, and Gavinskii, YuV
PATENT: RU 2282473 ISSUE DATE: 20060827
APPLICATION: 2002-37587 PP: 9pp.
ASSIGNEE: (ZAO \"Evalar\", Russia
24. 59344 DMID-LS-131; WOS-DMID-11/7/2006
Synthesis of Trifluoromethyl Ketone-Containing Glutamic Acid and Glutamine Peptides as Severe Acute Respiratory Syndrome Coronavirus 3cl Protease Inhibitors
Sydnes, M. et al.
Journal of Peptide Science 2006. 12: 109
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239905600102
25. 59345 DMID-LS-131; WOS-DMID-11/7/2006
An Efficient Method for the Synthesis of Peptide Aldehyde Libraries Employed in the Discovery of Sars Corona Virus Main Protease Inhibitors
Schmidt, M. et al.
Journal of Peptide Science 2006. 12: 168
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239905600337
26. 59346 DMID-LS-131; WOS-DMID-11/7/2006
Picornaviral 3cp Inhibitors. Multiple-Peptide Synthesis in Parallel and Biological Evaluation
Minchev, I. et al.
Journal of Peptide Science 2006. 12: 217
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239905600531
27. 59347 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Anti-alpha-herpesvirus drugs
Coen, Donald M
Alpha Herpesviruses 2006.: 361-381
28. 59348 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Pharmaceutical preparation of N -[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl] acetamide for use as antiviral agent
Laich, Tobias and Liebelt, Katrin
PATENT: WO 2006103011 ISSUE DATE: 20061005
APPLICATION: 2006 PP: 25pp.
ASSIGNEE: (Aicuris G.m.b.H. & Co. K.-G., Germany
29. 59349 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Method of screening for inhibitors of IRES-mediated translation and identification of antiviral peptides targeted to hepatitis C virus
Fear, Mark
PATENT: WO 2006102720 ISSUE DATE: 20061005
APPLICATION: 2006 PP: 197pp.
ASSIGNEE: (Telethon Institute for Child Health Research, Australia
30. 59350 DMID-LS-131; WOS-DMID-11/7/2006
Effects of Cidofovir Treatment on Cytokine Induction in Murine Models of Cowpox and Vaccinia Virus Infection
Knorr, C. et al.
Antiviral Research 2006. 72(2): 125-133
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241092900006
31. 59351 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Influenza virus NS1 protein protects against lymphohematopoietic pathogenesis in an in vivo mouse model
Hyland Lisa, Webby Richard, Sandbulte Matthew R, Clarke Ben, and Hou Sam
Virology 2006. 349(1): 156-163
32. 59352 DMID-LS-131; WOS-DMID-11/7/2006
Antiviral-Resistant Hbv: Can We Prevent This Monster From Growing?
Lok, A.
Journal of Clinical Virology 2006. 36: S22
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239067300066
33. 59353 DMID-LS-131; WOS-DMID-11/7/2006
New Hcv Antiviral Therapies
Zeuzem, S.
Journal of Clinical Virology 2006. 36: S49-S50
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239067300143
34. 59354 DMID-LS-131; WOS-DMID-11/7/2006
A Cell-Based Assay for Evaluating Potential Antiviral Agents Against Hcv
Aviel, S. et al.
Journal of Clinical Virology 2006. 36: S116
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239067300350
35. 59355 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Dithiocarbamate antiviral compounds for production of an agent for the treatment or prevention of a viral infection in the respiratory tract, and for a disinfecting agent
Gaudernak, Elisabeth, Grassauer, Andreas, Kuchler, Ernst, Muster, Thomas, and Seipelt, Joachim
PATENT: WO 2003007935 ISSUE DATE: 20030130
APPLICATION: 2002 PP: 50 pp.
ASSIGNEE: (Austria)
36. 59356 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Imidazo[1,2-b]pyridazines, Novel Nucleus with Potent and Broad Spectrum Activity against Human Picornaviruses: Design, Synthesis, and Biological Evaluation
Hamdouchi, Chafiq, Sanchez-Martinez, Concha, Gruber, Joseph, del Prado, Miriam, Lopez, Javier, Rubio, Almudena, and Heinz, Beverly A
Journal of Medicinal Chemistry 2003. 46(20): 4333-4341
37. 59357 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of 1,1-dioxodihydrobenzothiadiazines as antiviral agents
Darcy, Michael G, Dhanak, Dashyant, Duffy, Kevin J, Fitch, Duke M, Sarisky, Robert T, Shaw, Antony N, Tedesco, Rosanna, and Zimmerman, Michael N
PATENT: WO 2003059356 ISSUE DATE: 20030724
APPLICATION: 2002 PP: 103 pp.
ASSIGNEE: (Smithkline Beecham Corporation, USA
38. 59358 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of oxadiazolylphenoxyalkylisoxazoles as anti-picornaviral agents
Rhodes, Gerald and Nitz, Theodore J
PATENT: WO 2003020271 ISSUE DATE: 20030313
APPLICATION: 2002 PP: 37 pp.
ASSIGNEE: (Viropharma Incorporated, USA
39. 59359 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of dioxolane and oxathiolane nucleosides as antivirals and inhibitors of RNA-dependent RNA viral polymerase
Carroll, Steven S, MacCoss, Malcolm, Kuo, Lawrence C, Olsen, David B, Bhat, Balkrishen, Eldrup, Anne Bettina, Prhavc, Marija, Malik, Leila, and Bera, Sanjib
PATENT: WO 2003020222 ISSUE DATE: 20030313
APPLICATION: 2002 PP: 82 pp.
ASSIGNEE: (Merck & Co., Inc. USA and Isis Pharmaceuticals, Inc.
40. 59360 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of 6-[2-(1-pyridazinyl-4-piperidinyl)ethoxy]benzoxazoles and analogs as antiviral agents
Keith, Watson, Krippner, Guy, Stanislawski, Pauline, and McConnell, Darryl
PATENT: WO 2002050045 ISSUE DATE: 20020627
APPLICATION: 2001 PP: 76 pp.
ASSIGNEE: (Biota Scientific Management Pty Ltd., Australia
41. 59361 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Protease inhibitors as potential antiviral agents for the treatment of picornaviral infections
Wang, QMay
Antiviral Agents 2001.: 229-253
42. 59362 DMID-LS-131; SCIFINDER-DMID-11/7/2006
In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus
Semple, Susan J, Pyke, Simon M, Reynolds, Geoffrey D, and Flower, Robert LP
Antiviral Research 2001. 49(3): 169-178
43. 59363 DMID-LS-131; SCIFINDER-DMID-11/7/2006
1,2-Disubstituted 1,4-dihydro-4-oxoquinoline compounds and their antiviral activity
Tamura, Takashi, Kuriyama, Haruo, Agoh, Masanobu, Agoh, Yumi, Soga, Manabu, and Mori, Teruyo
PATENT: EP 1081138 ISSUE DATE: 20010307
APPLICATION: 2000-53137 PP: 64 pp.
ASSIGNEE: (Maruishi Pharmaceutical Co., Ltd. Japan
44. 59364 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Preparation of (heterocyclyl)alkoxy benzaldehyde oximes as antiviral agents
Wu, Wen-Yang, Watson, Keith, Mcconnell, Darryl, Jin, Betty, and Krippner, Guy
PATENT: WO 2000078746 ISSUE DATE: 20001228
APPLICATION: 2000 PP: 84 pp.
ASSIGNEE: (Biota Scientific Management Pty. Ltd., Australia
45. 59365 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Anti-rhinovirus activity of 3-methylthio-5-aryl-4-isothiazolecarbonitrile derivatives
Garozzo, A, Cutri, CCC, Castro, A, Tempera, G, Guerrera, F, Sarva, MC, and Geremia, E
Antiviral Research 2000. 45(3): 199-210
46. 59366 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Anti-viral imidazo[1,2-a]pyridine derivatives and their pharmaceutical formulations and use
Ezquerra-Carrera, Jesus, Gruber, Joseph Michael, Hamdouchi, Chafiq Hamdouchi, Holmes, Richard Elmer, and Spitzer, Wayne Alfred
PATENT: WO 9959587 ISSUE DATE: 19991125
APPLICATION: 98 PP: 138 pp.
ASSIGNEE: (Eli Lilly and Company, USA
47. 59367 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes
Matthews, DA, Dragovich, PS, Webber, SE, Fuhrman, SA, Patick, AK, Zalman, LS, Hendrickson, TF, Love, RA, Prins, TJ, Marakovits, JT, Zhou, R, Tikhe, J, Ford, CE, Meador, JW, Ferre, RA, Brown, EL, Binford, SL, Brothers, MA, Delisle, DM, and Worland, ST
Proceedings of the National Academy of Sciences of the United States of America 1999. 96(20): 11000-11007
48. 59368 DMID-LS-131; SCIFINDER-DMID-11/7/2006
In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease
Patick, AK, Binford, SL, Brothers, MA, Jackson, RL, Ford, CE, Diem, MD, Maldonado, F, Dragovich, PS, Zhou, R, Prins, TJ, Fuhrman, SA, Meador, JW, Zalman, LS, Matthews, DA, and Worland, ST
Antimicrobial Agents and Chemotherapy 1999. 43(10): 2444-2450
49. 59369 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Anti-picornavirus activity of synthetic flavon-3-yl esters
Conti, C, Mastromarino, P, Sgro, R, and Desideri, N
Antiviral Chemistry & Chemotherapy 1998. 9(6): 511-515
50. 59370 DMID-LS-131; WOS-DMID-11/7/2006
E7 Proteins From High- and Low-Risk Human Papillomaviruses Bind to Tgf-Beta-Regulated Smad Proteins and Inhibit Their Transcriptional Activity
Habig, M. et al.
Archives of Virology 2006. 151(10): 1961-1972
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000240723300005
51. 59371 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Synthesis and in vitro evaluation of the anti-viral activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides
Carta, Antonio, Loriga, Giovanni, Piras, Sandra, Paglietti, Giuseppe, Ferrone, Marco, Fermeglia, Maurizio, Pricl, Sabrina, La Colla, Paolo, Secci, Barbara, Collu, Gabriella, and Loddo, Roberta
Medicinal Chemistry 2006. 2(6): 577-589
52. 59372 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Application of quercetin-3-b-galactoside in medicine for inhibiting replication of SARS coronavirus and common cold virus HCoV-229E
Zhu, Weiliang, Pan, Chunmu, Chen, Lili, Shen, Xu, Chen, Gang, Luo, Cheng, Xu, Weijun, Luo, Xiaomin, Liu, Hong, Shen, Jianhua, Chen, Kaixian, and Jiang, Hualiang
PATENT: CN 1830449 ISSUE DATE: 20060913
APPLICATION: 1002-4349 PP: 12pp.
ASSIGNEE: (Shanghai Institute of Materia Medica, Chinese Academy of Sciences Peop. Rep. China and Singapore Polytechnic)
53. 59373 DMID-LS-131; SCIFINDER-DMID-11/7/2006
High and low risk human papillomaviruses: disease links, biology, immunology and vaccine development
Brinkman, Joeli A, Fahey, Laura M, Kast, Dieuwertje J, Da Silva, Diane M, and Kast, WMartin
Viral Oncogenesis 2006.: 75-105
54. 59374 DMID-LS-131; SCIFINDER-DMID-11/7/2006
Pyrrolo[2,3-b]pyridin-4-yl-amines and pyrrolo[2,3-b]pyrimidin-4-yl-amines as janus kinase inhibitors and their preparation, pharmaceutical compositions and use for treatment of diseases
Rodgers, James D, Wang, Heisheng, Combs, Andrew P, and Sparks, Richard B
PATENT: WO 2006069080 ISSUE DATE: 20060629
APPLICATION: 2005 PP: 86 pp.
ASSIGNEE: (Incyte Corporation, USA