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1. 56055 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy

De Bolle, L, Naesens, L, and De Clercq, E

Clin Microbiol Rev 2005. 18(1): 217-245


2. 56056 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD


Huang, YC, Li, Z, Brighton, LE, Carson, JL, Becker, S, and Soukup, JM

Am J Physiol Lung Cell Mol Physiol 2005.


3. 56057 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Amino substituted derivatives of 5'-amino-5'-deoxy-5'-noraristeromycin

Yang, M and Schneller, SW

Bioorg Med Chem 2005. 13(3): 877-882


4. 56058 DMID-LS-84; EMBASE-DMID-1/18/2005 ; DMID-LSLOAD

Efficacy of a 24-week course of PEG-interferon [alpha]-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance

Santantonio, Teresa, Fasano, Massimo, Sinisi, Emanuele, Guastadisegni, Angela, Casalino, Caterina, Mazzola, Michele, Francavilla, Ruggiero, and Pastore, Giuseppe

Journal of Hepatology 2005. In Press, Corrected Proof


5. 56059 DMID-LS-84; EMBASE-DMID-1/18/2005 ; DMID-LSLOAD

Synthesis and anti-viral activity of a series of D- and L-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system

Shi, Junxing, Du, Jinfa, Ma, Tianwei, Pankiewicz, Krzysztof W, Patterson, Steven E, Tharnish, Phillip M, McBrayer, Tamara R, Stuyver, Lieven J, Otto, Michael J, and Chu, Chung K

Bioorganic & Medicinal Chemistry 2005. In Press, Corrected Proof


6. 56060 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Virological effects of ISIS 14803, an antisense oligonucleotide inhibitor of hepatitis C virus (HCV) internal ribosome entry site (IRES), on HCV IRES in chronic hepatitis C patients and examination of the potential role of primary and secondary HCV resistance in the outcome of treatment

Soler, M, McHutchison, JG, Kwoh, TJ, Dorr, FA, and Pawlotsky, JM

Antivir Ther 2004. 9(6): 953-68


7. 56061 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Nitric oxide inhibits the replication cycle of severe acute respiratory syndrome coronavirus

Akerstrom, S, Mousavi-Jazi, M, Klingstrom, J, Leijon, M, Lundkvist, A, and Mirazimi, A

J Virol 2005. 79(3): 1966-9


8. 56062 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

The Predominant Mechanism by Which Ribavirin Exerts Its Antiviral Activity In Vitro against Flaviviruses and Paramyxoviruses Is Mediated by Inhibition of IMP Dehydrogenase

Leyssen, P, Balzarini, J, De Clercq, E , and Neyts, J

J Virol 2005 . 79(3): 1943-1947


9. 56063 DMID-LS-84; EMBASE-DMID-1/18/2005 ; DMID-LSLOAD

Identification and characterization of nonsubstrate based inhibitors of the essential dengue and West Nile virus proteases

Ganesh, Vannakambadi K, Muller, Nik, Judge, Ken, Luan, Chi-Hao, Padmanabhan, Radhakrishnan, and Murthy, Krishna HM

Bioorganic & Medicinal Chemistry 2005. 13(1): 257-264


10. 56064 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

West nile virus inhibits the signal transduction pathway of alpha interferon

Guo, JT, Hayashi, J, and Seeger, C

J Virol 2005. 79(3): 1343-50


11. 56065 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Antiviral Compounds From Traditional Chinese Medicines Galla Chinese as Inhibitors of Hcvns3 Protease

Duan, DL, Li, ZQ, Luo, HP, Zhang, W, Chen, LR, and Xu, XJ

Bioorganic & Medicinal Chemistry Letters 2004. 14(24): 6041-6044

12. 56066 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives

Luoni, GM, McGuigan, C, Andrei, G, Snoeck, R, De Clercq, E, and Balzarini, J

Antivir Chem Chemother 2004. 15(6): 333-341


13. 56067 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family

Bidet, O, McGuigan, C, Snoeck, R, Andrei, G, De, Clercq E, and Balzarini, J

Antivir Chem Chemother 2004. 15(6): 329-32


14. 56068 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Inactivation of Dengue Virus by Methylene Blue/Narrow Bandwidth Light System

Huang, Q, Fu, WL, Chen, B, Huang, JF, Zhang, X, and Xue, Q

Journal of Photochemistry and Photobiology B-Biology 2004. 77(1-3): 39-43

15. 56069 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

West Nile virus: recent experience with the model virus approach

Kreil, TR

Dev Biol (Basel) 2004. 118: 101-5


16. 56070 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Longer Treatment Duration With Peginterferon Alfa-2a (40kd) (Pegasys (R)) and Ribavirin (Copegus (R)) in Naive Patients With Chronic Hepatitis C and Detectable Hcv Rna by Week 4 of Therapy: Final Results of the Randomized, Multicenter Teravic-4 Study

Sanchez-Tapias, JM, Diago, M, Escartin, P, Enriquez, J, Moreno, R, Romero-Gomez, M, Barcena, R, Crespo, J, Andrade, R, Perez, R, Suarez, MJ, Planas, R, Sola, R, Garcia-Bengoechea, M, Garcia-Samaniego, J, Berenguer, J, Berenguer, J, Montoro, M, Del Olmo, J, Del Olmo, J, Lopez, G, Tome, S, Casanovas, T, Castellanos, G, and Castro, A

Hepatology 2004. 40(4): 218A

17. 56071 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Pharmacokinetic-Pharmacodynamic Relationships of Merimepodib and Ribavirin in Pegylated Interferon-Alfa/Ribavirin/Merimepodib Treated Genotype-1 Hcv Patients Non-Responsive to Previous Therapy With Interferon-Alfa/Ribavirin

Zha, JH, Garg, V, Mcnair, L, Marcellin, P, Alam, J, Purdy, S, and Ette, E

Hepatology 2004. 40(4): 250A

18. 56072 DMID-LS-84; EMBASE-DMID-1/18/2005 ; DMID-LSLOAD

Prophylaxis of acute respiratory virus infections using nucleic acid-based drugs

Wong, Jonathan P, Nagata, Les P, Christopher, Mary E, Salazar, Andres M, and Dale, Roderic MK

Vaccine 2005. In Press, Uncorrected Proof


19. 56073 DMID-LS-84; EMBASE-DMID-1/18/2005 ; DMID-LSLOAD

5'-Noraristeromycin derivatives isomeric to aristeromycin and 2'-deoxyaristeromycin

Yin, Xue-qiang and Schneller, Stewart W

Tetrahedron 2005. In Press, Corrected Proof


20. 56074 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Antiviral effect of chinonin against herpes simplex virus

Jiang, J, Li, S, Li, M, and Xiang, J

J Huazhong Univ Sci Technolog Med Sci 2004. 24(5): 521-4


21. 56075 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Randomized, Double-Blind Study Comparing Adefovir Dipivoxil (Adv) Plus Emtricitabine (Ftc) Combination Therapy Versus Adv Alone in Hbeag(+) Chronic Hepatitis B: Efficacy and Mechanisms of Treatment Response

Lau, G, Cooksley, H, Ribeiro, RM, Powers, KA, Bowden, S, Mommeja-Marin, H, Mondou, E, Lewin, S, Rousseau, F, Perelson, AS, Locarnini, S, and Naoumov, NV

Hepatology 2004. 40(4): 272A

22. 56076 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

The Highly Specific Carbohydrate-Binding Protein Cyanovirin-N: Structure, Anti-HIV/Ebola Activity and Possibilities for Therapy

Barrientos, LG and Gronenborn, AM

Mini Rev Med Chem 2005. 5(1): 21-31


23. 56077 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Anti-HBV effect of liposome-encapsulated matrine in vitro and in vivo

Li, CQ, Zhu, YT, Zhang, FX, Fu, LC, Li, XH, Cheng, Y, and Li, XY

World J Gastroenterol 2005. 11(3): 426-8


24. 56078 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C virus

Fillebeen, C, Rivas-Estilla, AM, Bisaillon, M, Ponka, P, Muckenthaler, M, Hentze, MW, Koromilas, AE, and Pantopoulos, K

J Biol Chem 2005.


25. 56079 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Antiviral activity of the volatile oils of Melissa officinalis L. against Herpes simplex virus type-2

Allahverdiyev, A, Duran, N, Ozguven, M, and Koltas, S

Phytomedicine 2004. 11(7-8): 657-61


26. 56080 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

A Pilot Trial of Thymalfasin (Thymosin Alpha-1) in Combination With Peginterferon Alpha-2a (Peg-Ifn2a) and Ribavirin in Hcv Non-Responders: 48-Week (End of Therapy) Results

Poo, JL, Sanchez-Avila, F, Kershenobich, D, Samper, XG, Gongora, J, Sandoval, MG, Oest, JA, Martins, EB, and Uribe, M

Hepatology 2004. 40(4): 336A

27. 56081 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Molecular Mechanism Susceptibility Profile of Biln-2061 to Various Hepatitis C Virus Genotypes and Ns3-Ns4a Protease Inhibitor Mutation: D168a and D168v.

Courcambeck, J, Perbost, R, Chabaud, P, Pepe, G, Bouzidi, M, Mabrouk, K, Sabatier, JM, and Halfon, P

Hepatology 2004. 40(4): 385A

28. 56082 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Modelling of anti-HSV activity of lactoferricin analogues using amino acid descriptors

Jenssen, H, Gutteberg, TJ, and Lejon, T

J Pept Sci 2004.


29. 56083 DMID-LS-84; EMBASE-DMID-1/18/2005 ; DMID-LSLOAD

Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists

Merriman, Gregory H, Ma, Liang, Shum, Patrick, McGarry, Daniel, Volz, Frank, Sabol, Jeffrey S, Gross, Alexandre, Zhao, Zhicheng, Rampe, David, and Wang, Lin

Bioorganic & Medicinal Chemistry Letters 2005. 15(2): 435-438


30. 56084 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

A Novel Animal Model to Assess Hcv Ns3 Center Dot 4a Protease Inhibitors Validated Using Vx-950 and Biln 2061

Kalkeri, G, Almquist, S, Perni, R, and Kwong, A

Hepatology 2004. 40(4): 402A

31. 56085 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Nucleotides and Pronucleotides of 2,2-Bis(hydroxymethyl)methylenecyclopropane Analogues of Purine Nucleosides: Synthesis and Antiviral Activity

Yan, Z, Kern, ER, Gullen, E, Cheng, YC, Drach, JC, and Zemlicka, J

J Med Chem 2005. 48(1): 91-99


32. 56086 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

In Vitro Resistance Mutations Against Vx-950 and Biln 2061, Two Hcv Protease Inhibitor Clinical Candidates: Single-Resistance, Cross-Resistance, and Fitness

Lin, C, Rao, BG, Luong, YP, Fulghum, JR, Brennan, DL, Wei, YY, Frantz, JD, Lippke, J, Hsiao, HM, Ma, S, Lin, K, Maxwell, JP, Cottrell, KM, Gates, CA, Perni, RB, and Kwong, AD

Hepatology 2004. 40(4): 404A

33. 56087 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

High-Throughput Screening of Anti-Hcv Drug Candidates Using an Elisa-Based Hcv Replicon Assay

Tan, H, Hong, J, Seiwert, S, and Blatt, LM

Hepatology 2004. 40(4): 407A

34. 56088 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Safety, Tolerance, Pharmacokinetics and Pharmacodynamics of Remofovir, a Livertargeting Prodrug of Pmea in Hbv Patients Following Daily Dosing for 28 Days.

Lin, CC, Chao, YC, Lai, MY, Chang, TT, Chuang, WL, Yang, SS, Braeckman, R, and Chen, DS

Hepatology 2004. 40(4): 658A-659A

35. 56089 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Molecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV)

Chow, KY, Hon, CC, Hui, RK, Wong, RT, Yip, CW, Zeng, F, and Leung, FC

Genomics Proteomics Bioinformatics 2003. 1(4): 247-62


36. 56090 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Phosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV

Gudmundsson, KS, Wang, Z, Daluge, SM, Johnson, LC, Hazen, R, Condreay, LD, and McGuigan, C

Nucleosides Nucleotides Nucleic Acids 2004. 23(12): 1929-37


37. 56091 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Selection and Characterization of Hepatitis C Virus Replicons Resistant to Potent Ns5b Polymerase Inhibitors.

Lu, LJ, Mo, HM, Pilot-Matias, T, Dekhtyar, T, Ng, T, Pithawalla, R, Masse, S, Pratt, J, Donner, P, Maring, C, and Molla, A

Hepatology 2004. 40(4): 694A

38. 56092 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity

Kirby, TO, Rivera, A, Rein, D, Wang, M, Ulasov, I, Breidenbach, M, Kataram, M, Contreras, JL, Krumdieck, C, Yamamoto, M, Rots, MG, Haisma, HJ, Alvarez, RD, Mahasreshti, PJ, and Curiel, DT

Clin Cancer Res 2004. 10(24): 8697-703


39. 56093 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Synthesis and Antiviral Activity of New 4-(Phenylamino)Thieno[2,3-B]Pyridine Derivatives

Bernardino, AMR, Pinheiro, LCS, Ferreira, VF, Azevedo, AR, Carneiro, JWD, Souza, TML, and Frugulhetti Icpp

Heterocyclic Communications 2004. 10(6): 407-410

40. 56094 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Isolation and Characterization of Herpes Simplex Virus Type 1 Resistant to Arninothiazolylphenyl-Based Inhibitors of the Viral Helicase-Primase

Liuzzi, M, Kibler, P, Bousquet, C, Harji, F, Bolger, G, Garneau, M, Lapeyre, N, Mccollum, RS, Faucher, AM, Simoneau, B, and Cordingley, MG

Antiviral Research 2004. 64(3): 161-170

41. 56095 DMID-LS-84; PUBMED-DMID-1/18/2005 ; DMID-LSLOAD

Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex

Tugizov, S, Berline, J, Herrera, R, Penaranda, ME, Nakagawa, M, and Palefsky, J

J Virol 2005. 79(2): 1099-112


42. 56096 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Antiviral and Antiplasmodial Spirodihydrobenzofuran Terpenes From the Fungus Stachybotrys Nephrospora

Sawadjoon, S, Kittakoop, P, Isaka, M, Kirtikara, K, Madla, S, and Thebtaranonth, Y

Planta Medica 2004. 70(11): 1085-1087

43. 56097 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Inhibition of Parainfluenza Virus Type 3 and Newcastle Disease Virus Hemagglutinin-Neuraminidase Receptor Binding: Effect of Receptor Avidity and Steric Hindrance at the Inhibitor Binding Sites

Porotto, M, Murrell, M, Greengard, O, Lawrence, MC, Mckimm-Breschkin, JL, and Moscona, A

Journal of Virology 2004. 78(24): 13911-13919

44. 56098 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Cooperation Between Different Forms of the Human Papillomavirus Type 1 E4 Protein to Block Cell Cycle Progression and Cellular Dna Synthesis

Knight, GL, Grainger, JR, Gallimore, PH, and Roberts, S

Journal of Virology 2004. 78(24): 13920-13933

45. 56099 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Genetic Screen for Monitoring Severe Acute Respiratory Syndrome Coronavirus 3c-Like Protease

Parera, M, Clotet, B, and Martinez, MA

Journal of Virology 2004. 78(24): 14057-14061

46. 56100 DMID-LS-84; WOS-DMID-1/18/2005 ; DMID-LSLOAD

Amantadine Has Direct Inhibitory Effects Against Hepatitis a Internal Ribosomal Entry Site-Mediated Translation.

Kanda, T, Yokosuka, O, Imazeki, F, Fujiwara, K, Saisho, H, and Nagao, K

Hepatology 2004. 40(4): 286A

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