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1. 56101 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Assessment of Adverse Reactions and Pharmacokinetics of Ribavirin in Combination with Interferon alpha-2b in Patients with Chronic Hepatitis C

Uchida, M, Hamada, A, Yamasaki, M, Fujiyama, S, Sasaki, Y, and Saito, H

Drug Metab Pharmacokinet 2004. 19(6): 438-443


2. 56102 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Use of CTC-96 for the topical antiviral therapeutic and prophylactic treatment of adenoviruses and their associated diseases

Gershon, David

PATENT: WO 2005004817 ISSUE DATE: 20050120

APPLICATION: 2004 PP: 20 pp.

ASSIGNEE: (Redox Pharmaceutical Corporation Audubon Biomedical Science and Technology Park, USA

3. 56103 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor

Cianci, C, Meanwell, N, and Krystal, M

J Antimicrob Chemother 2005.


4. 56104 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Multivalent HSA Conjugates of 3'-Sialyllactose are Potent Inhibitors of Adenoviral Cell Attachment and Infection

Johansson, SM, Arnberg, N, Elofsson, M, Wadell, G, and Kihlberg, J

Chembiochem 2005. 6(2): 358-364


5. 56105 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Preparation of modified fluorinated (2'R)-2'-deoxy-2'-fluoro-2'-C-methyl nucleoside analogs as antiviral agents

Clark, Jeremy

PATENT: WO 2005003147 ISSUE DATE: 20050113

APPLICATION: 2004 PP: 228 pp.

ASSIGNEE: (Pharmasset, Ltd. Barbados

6. 56106 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Chinese medicinal herbs for influenza

Chen, X, Wu, T, Liu, G, Wang, Q, Zheng, J, Wei, J, Ni, J, Zhou, L, Duan, X, and Qiao, J

Cochrane Database Syst Rev 2005.(1): CD004559


7. 56107 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein

Modis, Y. et al.

Journal of Virology 2005. 79(2): 1223-1231


8. 56108 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Korean medicinal plant extracts exhibit antiviral potency against viral hepatitis

Jacob, JR, Korba, BE, You, JE, Tennant, BC, and Kim, YH

J Altern Complement Med 2004. 10(6): 1019-26


9. 56109 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Comparison of the Antiviral Activities of Alkoxyalkyl and Alkyl Esters of Cidofovir against Human and Murine Cytomegalovirus Replication In Vitro

Wan, WB, Beadle, JR, Hartline, C, Kern, ER, Ciesla, SL, Valiaeva, N, and Hostetler, KY

Antimicrob Agents Chemother 2005. 49(2): 656-62


10. 56110 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Triple Combination of Thymalfasin, Peginterferon Alfa-2a and Ribavirin in Patients With Chronic Hepatitis C Who Have Failed Prior Interferon and Ribavirin Treatment: 24-Week Interim Results of a Pilot Study

Poo, J. et al.

Journal of Gastroenterology and Hepatology 2004. 19(12): S79-S81


11. 56111 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Conservation of Amino Acids in Human Rhinovirus 3C Protease Correlates with Broad-Spectrum Antiviral Activity of Rupintrivir, a Novel Human Rhinovirus 3C Protease Inhibitor

Binford, SL, Maldonado, F, Brothers, MA, Weady, PT, Zalman, LS, Meador, JW 3rd, Matthews, DA, and Patick, AK

Antimicrob Agents Chemother 2005. 49(2): 619-626


12. 56112 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Synthesis and antiviral activity of some novel isatin derivatives

Selvam, P, Rajasekaran, A, Dharamsi, ALaeeque, Ahmed, K, Musthafa, SMohammed, Poornima, K, Pournami, KA, Murugesh, N, Chandramohan, M, and De Clercq, E

Asian Journal of Chemistry 2005. 17(1): 443-448

13. 56113 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Peginterferon-Alpha-2a (40kd) Plus Ribavirin - a Review of Its Use in Hepatitis C Virus and Hiv Co-Infection

Plosker, G. and Keating, G.

Drugs 2004. 64(24): 2823-2843


14. 56114 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series

Amblard, F, Aucagne, V, Guenot, P, Schinazi, RF, and Agrofoglio, LA

Bioorg Med Chem 2005. 13(4): 1239-48


15. 56115 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Disialoundecasaccharide chain asparagine/fatty acid amide and medical drug containing the same

Kajihara, Yasuhiro, Maeda, Hiroaki, and Fukae, Kazuhiro

PATENT: WO 2005000906 ISSUE DATE: 20050106

APPLICATION: 2004 PP: 27 pp.

ASSIGNEE: (Otsuka Chemical Co., Ltd. Japan and Sanyo Chemical Industries, Ltd.

16. 56116 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Virtual Screening of Novel Noncovalent Inhibitors for SARS-CoV 3C-like Proteinase

Liu, Z, Huang, C, Fan, K, Wei, P, Chen, H, Liu, S, Pei, J, Shi, L, Li, B, Yang, K, Liu, Y, and Lai, L

J Chem Inf Comput Sci 2005. 45(1): 10-7


17. 56117 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Preparation of peptidyl protease inhibitors for coronaviruses and SARS-CoV

Cai, Sui Xiong, Kemnitzer, William E, Zhang, Hong, and Zhang, Han-Zhong

PATENT: WO 2004101742 ISSUE DATE: 20041125

APPLICATION: 2004 PP: 64 pp.

ASSIGNEE: (Cytovia, Inc USA

18. 56118 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Assays for glucosidase inhibitors with potential antiviral activities: secreted alkaline phosphatase as a surrogate marker

Norton, PA, Conyers, B, Gong, Q, Steel, LF, Block, TM, and Mehta, AS

J Virol Methods 2005. 124(1-2): 167-72


19. 56119 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Virus-encoded chemokine receptors - putative novel antiviral drug targets

Rosenkilde, Mette M

Neuropharmacology 2005. 48(1): 1-13

20. 56120 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Antiviral compounds derived from naturally occurring proteins

Pellegrini, Antonio and Engels, Monika

Current Medicinal Chemistry: Anti-Infective Agents 2005. 4(1): 55-66

21. 56121 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Genomic and bioinformatics analysis of HAdV-7, a human adenovirus of species B1 that causes acute respiratory disease: implications for vector development in human gene therapy

Purkayastha, A, Su, J, Carlisle, S, Tibbetts, C, and Seto, D

Virology 2005. 332(1): 114-129


22. 56122 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

(Benzoylamino)isoquinolinecarboxamide derivatives as anti-coronavirus drugs

Fujii, Nobutaka and Yamamoto, Naoki

PATENT: WO 2005004868 ISSUE DATE: 20050120

APPLICATION: 2004 PP: 25 pp.


23. 56123 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Severe acute respiratory syndrome coronavirus infection of golden syrian hamsters

Roberts, Anjeanette, Vogel, Leatrice, Guarner, Jeannette, Hayes, Norman, Murphy, Brian, Zaki, Sherif, and Subbarao, Kanta

Journal of Virology 2005. 79(1): 503-511

24. 56124 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Inhibitors of interaction of coronavirus intergenic sequence with polymerase complex

Lai, Derhsing and Phounsavan, Say Fone

PATENT: WO 2005000234 ISSUE DATE: 20050106

APPLICATION: 2004 PP: 42 pp.

ASSIGNEE: (Sars Scientific Corp., USA

25. 56125 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Application of human Brd4 protein fusion with E2 protein from papilloma virus or herpes virus for prevention of viral infections or treatment of viral diseases

You, Jianxin and Howley, Peter M

PATENT: WO 2005002526 ISSUE DATE: 20050113

APPLICATION: 2004 PP: 175 pp.

ASSIGNEE: (President and Fellows of Harvard College, USA

26. 56126 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Synthesis and antiviral activity of helioxanthin analogues

Yeo, H, Li, Y, Fu, L, Zhu, JL, Gullen, EA, Dutschman, GE, Lee, Y, Chung, R, Huang, ES, Austin, DJ, and Cheng, YC

J Med Chem 2005. 48(2): 534-46


27. 56127 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Inhibition of virus production in JC virus-infected cells by postinfection RNA interference

Orba, Yasuko, Sawa, Hirofumi, Iwata, Hiroshi, Tanaka, Shinya, and Nagashima, Kazuo

Journal of Virology 2004. 78(13): 7270-7273

28. 56128 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Synthesis and Antiviral Evaluation of Cis-Substituted Cyclohexenyl and Cyclohexanyl Nucleosides

Barral, K, Courcambeck, J, Pepe, G, Balzarini, J, Neyts, J, De Clercq, E, and Camplo, M

J Med Chem 2005. 48(2): 450-456


29. 56129 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Unedited Inhibition of Hbv Replication by Apobec3g

Seppen, J

Journal of Hepatology 2004. 41(6): 1068-1069


30. 56130 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Preparation of tetrahydrocarbazole derivatives as human papillomaviruses inhibitors

Boggs, Sharon Davis, Gudmundsson, Kristjan S, Richardson, Leah D'Aurora, and Sebahar, Paul Richard

PATENT: WO 2004110999 ISSUE DATE: 20041223

APPLICATION: 2004 PP: 69 pp.

ASSIGNEE: (Smithkline Beecham Corporation, USA

31. 56131 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

The road to new antiviral therapies

Jerome, Keith R

Clinical and Applied Immunology Reviews 2005. 5(1): 65-76

32. 56132 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Aminothiazole Inhibitors of Hcv Rna Polymerase

Shipps, G. et al.

Bioorganic & Medicinal Chemistry Letters 2005. 15(1): 115-119


33. 56133 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

HCV regulated proteins and anti-hepatitis C virus compounds

Berndt, Peter, Kilby, Peter Michael, and Rugman, Paul

PATENT: EP 1493750 ISSUE DATE: 20050105

APPLICATION: 2004-15098 PP: 346 pp.

ASSIGNEE: (F. Hoffmann-La Roche AG, Switz.

34. 56134 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Novel HCV shorter form core+1 proteins and polynucleotides for prophylaxis and diagnosis of HCV infections and for screening of anti-HCV agents

Mavromara, Penelope and Niki, Vassilaki

PATENT: EP 1493749 ISSUE DATE: 20050105

APPLICATION: 2003-29532 PP: 80 pp.

ASSIGNEE: (Institut Pasteur, Fr. and Institut Pasteur Hellenique)

35. 56135 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Inhibition of SARS-CoV replication by siRNA

Wu, CJ, Huang, HW, Liu, CY, Hong, CF, and Chan, YL

Antiviral Res 2005. 65(1): 45-8


36. 56136 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Enhancement of antiviral activity against hepatitis C virus in vitro by interferon combination therapy

Okuse, C, Rinaudo, JA, Farrar, K, Wells, F, and Korba, BE

Antiviral Res 2005. 65(1): 23-34


37. 56137 DMID-LS-85; SCIFINDER-DMID-2/1/2005 ; DMID-LSLOAD

Crystals of hepatitis C virus polymerase and/or hepatitis C virus polymerase-like proteins and their use for modeling and design of potential antiviral agents

Finzel, Barry C

PATENT: WO 2005001417 ISSUE DATE: 20050106

APPLICATION: 2004 PP: 459 pp.

ASSIGNEE: (Pharmacia & Upjohn Company, USA

38. 56138 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Increased sensitivity of SARS-coronavirus to a combination of human type I and type II interferons

Scagnolari, C, Vicenzi, E, Bellomi, F, Stillitano, MG, Pinna, D, Poli, G, Clementi, M, Dianzani, F, and Antonelli, G

Antivir Ther 2004. 9(6): 1003-11


39. 56139 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

The Effect of Hepatitis C on Progression to Aids Before and After Highly Active Antiretroviral Therapy

Dorrucci, M. et al.

Aids 2004. 18(17): 2313-2318


40. 56140 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Adefovir Dipivoxil as the Rescue Therapy for Lamivudine-Resistant Hepatitis B Post Liver Transplant

Wai, C. et al.

Transplantation Proceedings 2004. 36(8): 2313-2314


41. 56141 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein

Gripon, P, Cannie, I, and Urban, S

J Virol 2005. 79(3): 1613-22


42. 56142 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Hepatotoxicity of antiretrovirals : incidence, mechanisms and management

Nunez, M and Soriano, V

Drug Saf 2005. 28(1): 53-66


43. 56143 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Analogues of acyclic nucleosides derived from tris-(hydroxymethyl)phosphine oxide or bis-(hydroxymethyl)phosphinic acid coupled to DNA nucleobases

Nawrot, B, Michalak, O, De Clercq, E, and Stec, WJ

Antivir Chem Chemother 2004. 15(6): 319-328


44. 56144 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Treatment With Pegylated Interferon and Ribavarin in Hcv Infection With Genotype 2 or 3 for 14 Weeks: a Pilot Study

Dalgard, O. et al.

Hepatology 2004. 40(6): 1260-1265


45. 56145 DMID-LS-85; PUBMED-DMID-2/1/2005 ; DMID-LSLOAD

Antiviral effect of chinonin against herpes simplex virus

Anon 2004. 24(5): 521-524


46. 56146 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

Structure-Based Preliminary Analysis of Immunity and Virulence of Sars Coronavirus

Li, Y. et al.

Viral Immunology 2004. 17(4): 528-534


47. 56147 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

In Vitro Inhibition of Sars Virus Replication by Human Interferons

Dahl, H., Linde, A., and Strannegard, O.

Scandinavian Journal of Infectious Diseases 2004. 36(11-12): 829-831


48. 56148 DMID-LS-85; WOS-DMID-2/1/2005 ; DMID-LSLOAD

In Vitro Anti-Hsv-2 Activity and Mechanism of Action of Proanthocyanidin a-1 From Vaccinium Vitis-Idaea

Cheng, H. et al.

Journal of the Science of Food and Agriculture 2005. 85(1): 10-15


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