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1. 56432 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

The 4',4'-difluoro analog of 5'-noraristeromycin: A new structural prototype for possible antiviral drug development toward orthopoxvirus and cytomegalovirus

Roy, A, Schneller, SW, Keith, KA, Hartline, CB, and Kern, ER

Bioorg Med Chem 2005.


2. 56433 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Biological activities of isatin and its derivatives

Pandeya, SN, Smitha, S, Jyoti, M, and Sridhar, SK

Acta Pharm 2005. 55(1): 27-46


3. 56434 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

The Potential Anti-Hbv Effect of Amantadine in Combination With Ursodeoxycholic Acid and Biphenyl Dimethyl Dicarboxylate in Hepg2 2.2.15 Cells

Joo, S. and Lee, D.

Archives of Pharmacal Research 2005. 28(4): 451-457


4. 56435 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Anti-phosphatidylserine antibodies and antibody-antiviral agent conjugates for treating cancer and viral infection

Thorpe, Philip E, Soares, MMelina, and He, Jin

PATENT: US 2005025761 ISSUE DATE: 20050203

APPLICATION: 2003-52276 PP: 180 pp., Cont.-in-part of U.S. Ser. No. 621,269.

ASSIGNEE: (Board of Regents, the University of Texas System USA

5. 56436 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Potent and specific inhibition of SARS-CoV antigen expression by RNA interference

Tao, P, Zhang, J, Tang, N, Zhang, BQ, He, TC, and Huang, AL

Chin Med J (Engl) 2005. 118(9): 714-719


6. 56437 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors

Chen, LR, Wang, YC, Lin, YW, Chou, SY, Chen, SF, Liu, LT, Wu, YT, Kuo, CJ, Chen, TS, and Juang, SH

Bioorg Med Chem Lett 2005.


7. 56438 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Inhibition of hepatitis C virus core protein expression in immortalized human hepatocytes induces cytochrome c-independent increase in Apaf-1 and caspase-9 activation for cell death

Meyer, K, Basu, A, Saito, K, Ray, RB, and Ray, R

Virology 2005. 336(2): 198-207


8. 56439 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Development in lipid drugs

Raulin, J

Mini Rev Med Chem 2005. 5(5): 489-498


9. 56440 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Method of preventing virus: cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins

Garry, Robert F and Russell, Wilson

PATENT: WO 2005044992 ISSUE DATE: 20050519

APPLICATION: 2004 PP: 63 pp.

ASSIGNEE: (The Administrators of the Tulane Educational Fund, USA

10. 56441 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Synthesis and in Vitro Anti-Hbv and Anti-Hcv Activities of Ring-Expanded ("Fat") Nucleobases and Nucleosides Containing the Imidazo[4,5-E][1,3]Diazepine-4,8-Dione Ring System

Zhang, P., Korba, B., and Hosmane, R.

Antiviral Research 2005. 65(3): A56-A57


11. 56442 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Antiviral evaluation of plants from Brazilian Atlantic Tropical Forest

Andrighetti-Frohner, CR, Sincero, TC, da Silva, AC, Savi, LA, Gaido, CM, Bettega, JM, Mancini, M, de Almeida, MT, Barbosa, RA , Farias, MR, Barardi, CR, and Simoes, CM

Fitoterapia 2005.


12. 56443 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Preparation of nucleosides for treating viral infections caused by a Flaviviridae family virus

Roberts, Christopher D and Keicher, Jesse D

PATENT: US 2005090463 ISSUE DATE: 20050428

APPLICATION: 2004-9343 PP: 37 pp.

ASSIGNEE: (Genelabs Technologies, Inc. USA

13. 56444 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus

Basha, W, Kitagawa, R, Uhara, M, Imazu, H, Uechi, K, and Tanaka, J

Antivir Chem Chemother 2005. 16(2): 135-146


14. 56445 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Methods and compositions comprising diamines as antiinfective and antitubercular therapeutics, and preparation thereof

Bogatcheva, Elena, Protopopova, Marina, and Nikonenko, Boris

PATENT: WO 2005034857 ISSUE DATE: 20050421

APPLICATION: 2004 PP: 104 pp.

ASSIGNEE: (Sequella, Inc. USA

15. 56446 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Design, synthesis, and antipicornavirus activity of 1-[5-(4-arylphenoxy)alkyl]-3-pyridin-4-ylimidazolidin-2-one derivatives

Chang, CS, Lin, YT, Shih, SR, Lee, CC, Lee, YC, Tai, CL, Tseng, SN, and Chern, JH

J Med Chem 2005. 48(10): 3522-3535


16. 56447 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Inhibitory Action of Sulfated Polysaccharides on Dengue Virus Infection of Human Cells

Talarico, L. and Damonte, E.

Antiviral Research 2005. 65(3): A87


17. 56448 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Synthesis and structure-activity-relationships of 1H-imidazo[4,5-c]quinolines that induce interferon production

Gerster, JF, Lindstrom, KJ, Miller, RL , Tomai, MA, Birmachu, W, Bomersine, SN, Gibson, SJ, Imbertson, LM, Jacobson, JR, Knafla, RT, Maye, PV, Nikolaides, N, Oneyemi, FY, Parkhurst, GJ, Pecore, SE, Reiter, MJ, Scribner, LS, Testerman, TL, Thompson, NJ, Wagner, TL, Weeks, CE, Andre, JD, Lagain, D, Bastard, Y, and Lupu, M

J Med Chem 2005. 48(10): 3481-3491


18. 56449 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Identification of natural compounds with antiviral activities against SARS-associated coronavirus

Li, SY, Chen, C, Zhang, HQ, Guo, HY, Wang, H, Wang, L, Zhang, X, Hua, SN, Yu, J, Xiao, PG, Li, RS, and Tan, X

Antiviral Res 2005.


19. 56450 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Effect of antiviral treatment with entecavir on age- and dose-related outcomes of duck hepatitis B virus infection

Foster, Wendy K, Miller, Darren S, Scougall, Catherine A, Kotlarski, Ieva, Colonno, Richard J, and Jilbert, Allison R

Journal of Virology 2005. 79(9): 5819-5832

20. 56451 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

An anti-herpes simplex virus-type 1 agent from Xylaria mellisii (BCC 1005)

Pittayakhajonwut, Pattama, Suvannakad, Rapheephat, Thienhirun, Surang, Prabpai, Samran, Kongsaeree, Palangpon, and Tanticharoen, Morakot

Tetrahedron Letters 2005. 46(8): 1341-1344

21. 56452 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

Morrissey, DV, Blanchard, K, Shaw, L, Jensen, K, Lockridge, JA, Dickinson, B, McSwiggen, JA, Vargeese, C, Bowman, K, Shaffer, CS, Polisky, BA, and Zinnen, S

Hepatology 2005.


22. 56453 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Structural features and molecular evolution of bowman-birk protease inhibitors and their potential application

Qi, RF, Song, ZW, and Chi, CW

Acta Biochim Biophys Sin (Shanghai) 2005. 37(5): 283-292


23. 56454 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Duration of Infectivity and Rna of Venezuelan Equine Encephalitis, West Nile, and Yellow Fever Viruses Dried on Filter Paper and Maintained at Room Temperature

Guzman, H. et al.

American Journal of Tropical Medicine and Hygiene 2005 . 72(4): 474-477


24. 56455 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Rhodanine compositions for use as antiviral agents

Rajinder, Singh, Usha, Ramesh, Clough, Jeffrey, Issakani, Sarkiz D, and Look, Gary Charles

PATENT: WO 2005041951 ISSUE DATE: 20050512

APPLICATION: 2004 PP: 82 pp.

ASSIGNEE: (Rigel Pharmaceuticals, Inc. USA

25. 56456 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Design, Synthesis and Antiviral Activity of Novel 4,5-Disubstituted 7-(b-D-Ribofuranosyl)pyrrolo[2,3-d][1,2,3]triazines and the Novel 3-Amino-5-methyl-1-(b-D-ribofuranosyl)- and 3-Amino-5-methyl-1-(2-deoxy-b-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,7,8-hexaazaacenaphthylene as Analogues of Triciribine

Migawa, Michael T, Drach, John C, and Townsend, Leroy B

Journal of Medicinal Chemistry 2005. 48(11): 3840-3851

26. 56457 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Method for the treatment of herpes with cetyl myristate and cetyl palmitate

Meakin, Timothy David, Heatley, Craig Leonard, and Cadwallader, Dianne

PATENT: NZ 524311 ISSUE DATE: 20050225

APPLICATION: 2001 PP: 10 pp.

ASSIGNEE: (Meracol Corporation Limited, N. Z.

27. 56458 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Identification of naturally occurring amino acid variations that affect the ability of the measles virus C protein to regulate genome replication and transcription

Bankamp, B, Wilson, J, Bellini, WJ, and Rota, PA

Virology 2005. 336(1): 120-129


28. 56459 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Synthesis of Purinyl Homo-Carbonucleoside Derivatives of 2-Benzylcyclo-Penta[C]Pyrazol

Garcia, M. et al.

Synthesis-Stuttgart 2005.(6): 925-932


29. 56460 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Small Interfering Rna Inhibits Sars-Cov Nucleocapsid Gene Expression in Cultured Cells and Mouse Muscles

Zhao, P. et al.

Febs Letters 2005. 579(11): 2404-2410


30. 56461 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Synthesis of screening substrates for the directed evolution of sialic acid aldolase: towards tailored enzymes for the preparation of influenza A sialidase inhibitor analogues

Woodhall, T, Williams, G, Berry, A, and Nelson, A

Org Biomol Chem 2005. 3(9): 1795-1800


31. 56462 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Amantadine inhibits hepatitis A virus internal ribosomal entry site-mediated translation in human hepatoma cells

Kanda, T, Yokosuka, O, Imazeki, F, Fujiwara, K, Nagao, K, and Saisho, H

Biochem Biophys Res Commun 2005. 331(2): 621-629


32. 56463 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29

Brand, S, Zitzmann, K, Dambacher, J, Beigel, F, Olszak, T, Vlotides, G, Eichhorst, ST, Goke, B, Diepolder, H, and Auernhammer, CJ

Biochem Biophys Res Commun 2005. 331(2): 543-548


33. 56464 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication

Palese, Peter and O'Neill, Robert

PATENT: US 6890710 ISSUE DATE: 20050510

APPLICATION: 95-51778 PP: 66 pp., Cont.-in-part of U.S. Ser. No. 246,583.

ASSIGNEE: (Mount Sinai School of Medicine of New York University, USA

34. 56465 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Pathogenic significance of alpha-N-acetylgalactosaminidase activity found in the hemagglutinin of influenza virus

Yamamoto, N and Urade, M

Microbes Infect 2005. 7(4): 674-681


35. 56466 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Study on the resistance of severe acute respiratory syndrome-associated coronavirus

Wang, XW, Li, JS, Jin, M, Zhen, B, Kong, QX, Song, N, Xiao, WJ, Yin, J, Wei, W, Wang, GJ, Si, BY, Guo, BZ, Liu, C, Ou, GR, Wang, MN, Fang, TY, Chao, FH, and Li, JW

J Virol Methods 2005. 126(1-2): 171-177


36. 56467 DMID-LS-93; PUBMED-DMID-5/24/2005 ; DMID-LSLOAD

Avian Influenza

Zeitlin, GA and Maslow, MJ

Curr Infect Dis Rep 2005. 7(3): 193-199


37. 56468 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Anti-influenza A viral drug - amantadine

Miyamoto, Daisei and Suzuki, Yasuo

Sogo Rinsho 2005. 54(2): 352-357

38. 56469 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Natural Inhibitor of Influenza a-Pr8 Extracted From Cinnamon

Barak, I. and Ovadia, M.

Antiviral Research 2005. 65(3): A65


39. 56470 DMID-LS-93; WOS-DMID-5/24/2005 ; DMID-LSLOAD

Smallpox Antivirals: in Vitro Assay for Vaccinia Virus 17l Enzymatic Cleavage of Core Protein Precursors

Byrd, C. and Hruby, D.

Antiviral Research 2005. 65(3): A80


40. 56471 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Antiviral activity of phenolic polymers and cyclo-Saligenyl-pronucleotides towards SARS-related Coronavirus

Schmidtke, Michaela, Meier, Chris, Schacke, Michael, Helbig, Bjoern, Makarov, Vadim, Rabenau, Holger F, Cinatl, Jindrich Jr, and Wutzler, Peter

Chemotherapie Journal 2005. 14(1): 16-21

41. 56472 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Anti-coronavirus agent

Sugiura, Koji and Ono, Yasuharu

PATENT: WO 2005037296 ISSUE DATE: 20050428

APPLICATION: 2003 PP: 18 pp.

ASSIGNEE: (Toagosei Co., Ltd. Japan

42. 56473 DMID-LS-93; SCIFINDER-DMID-5/24/2005 ; DMID-LSLOAD

Preparation of novel cycloalkyl[b] condensed indoles for treating human papillomaviruses

Boggs, Sharon Davis, Catalano, John G, Gudmundsson, Kristjan S, D'Aurora Richardson, Leah, and Sebahar, Paul Richard

PATENT: WO 2005023245 ISSUE DATE: 20050317

APPLICATION: 2004 PP: 89 pp.

ASSIGNEE: (Smithkline Beecham Corporation, USA

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