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1. 57722 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Isolation of an Antiviral Polysaccharide, Nostoflan, from a Terrestrial Cyanobacterium, Nostoc flagelliforme

Kanekiyo, Kenji, Lee, Jung-Bum, Hayashi, Kyoko, Takenaka, Hiroyuki, Hayakawa, Yumiko, Endo, Shunro, and Hayashi, Toshimitsu

Journal of Natural Products 2005. 68(7): 1037-1041

2. 57723 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Ready-for-use injectable solution of 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amine-1H-purin-6(9H)-one and a closed system for packing the solution with a process for eliminating alkaline residuals of 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amine-1H-purin-6(9H)-one crystals

Perillo, Heno, Campos Neto, Jose, and Crucelli, Marcio

PATENT: WO 2005051286 ISSUE DATE: 20050609

APPLICATION: 2004 PP: 37 pp.

ASSIGNEE: (Halex Istar Industria Farmaceutica Ltda., Brazil and Labogen S/A Quimica Fina E Biotecnologia)

3. 57724 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Effects of orally administered bovine lactoferrin and lactoperoxidase on influenza virus infection in mice

Shin, K, Wakabayashi, H, Yamauchi, K, Teraguchi, S, Tamura, Y, Kurokawa, M, and Shiraki, K

J Med Microbiol 2005. 54(Pt 8): 717-23


4. 57725 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663

Maga, G, Gemma, S, Fattorusso, C, Locatelli, GA, Butini, S, Persico, M, Kukreja, G, Romano, MP, Chiasserini, L, Savini, L, Novellino, E, Nacci, V, Spadari, S, and Campiani, G

Biochemistry 2005. 44(28): 9637-9644


5. 57726 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Inhibition of hepatitis B virus gene expression and replication by helioxanthin and its derivative

Li, Y, Fu, L, Yeo, H, Zhu, JL, Chou, CK, Kou, YH, Yeh, SF, Gullen, E, Austin, D, and Cheng, YC

Antivir Chem Chemother 2005. 16(3): 193-201


6. 57727 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Characterization of hepatitis B virus inhibition by novel 2'-fluoro-2',3'-unsaturated beta-D- and L-nucleosides

Pai, SB, Pai, RB, Xie, MY, Beker, T, Shi, J, Tharnish, PM, Chu, CK, and Schinazi, RF

Antivir Chem Chemother 2005. 16(3): 183-92


7. 57728 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Achievements and challenges in antiviral drug discovery

Littler, E and Oberg, B

Antivir Chem Chemother 2005. 16(3): 155-68


8. 57729 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Synthesis and Biological Evaluation of Acyclic 3-[(2-Hydroxyethoxy)methyl] Analogues of Antiviral Furo- and Pyrrolo[2,3-d]pyrimidine Nucleosides(1)

Janeba, Z, Balzarini, J, Andrei, G, Snoeck, R, De, Clercq E, and Robins, MJ

J Med Chem 2005. 48(14): 4690-6


9. 57730 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole-N-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase

Harper, S, Avolio, S, Pacini, B, Di, Filippo M, Altamura, S, Tomei, L, Paonessa, G, Di, Marco S, Carfi, A, Giuliano, C, Padron, J, Bonelli, F, Migliaccio, G, De, Francesco R, Laufer, R, Rowley, M, and Narjes, F

J Med Chem 2005. 48(14): 4547-57


10. 57731 DMID-LS-97; WOS-DMID-7/18/2005 ; DMID-LSLOAD

A Novel Topical Antiviral Agent, Pcl-016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/Nzw Rabbit Ocular Model

Romanowski, E. et al.

Investigative Ophthalmology & Visual Science 2005. 46


11. 57732 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids

Wieland, SF, Eustaquio, A, Whitten-Bauer, C, Boyd, B, and Chisari, FV

Proc Natl Acad Sci U S A 2005. 102(28): 9913-7


12. 57733 DMID-LS-97; PUBMED-DMID-7/18/2005 ; DMID-LSLOAD

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

Shie, JJ, Fang, JM, Kuo, TH, Kuo, CJ, Liang, PH, Huang, HJ, Wu, YT, Jan, JT, Cheng, YS, and Wong, CH

Bioorg Med Chem 2005.


13. 57734 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Preparation of dihydroquinazolines as antiviral agents

Wunberg, Tobias, Baumeister, Judith, Jeske, Mario, Nell, Peter, Nikolic, Susanne, Suessmeier, Frank, Zimmermann, Holger, Grosser, Rolf, Hewlett, Guy, Keldenich, Joerg, Lang, Dieter, and Henninger, Kerstin

PATENT: WO 2005047278 ISSUE DATE: 20050526

APPLICATION: 2004 PP: 50 pp.

ASSIGNEE: (Bayer Healthcare A.-G., Germany

14. 57735 DMID-LS-97; WOS-DMID-7/18/2005 ; DMID-LSLOAD

The 'supervirus'? Lessons From Il-4-Expressing Poxviruses

Stanford, M. and Mcfadden, G.

Trends in Immunology 2005. 26(6): 339-345


15. 57736 DMID-LS-97; WOS-DMID-7/18/2005 ; DMID-LSLOAD

Docking Versus Pharmacophore Model Generation: a Comparison of High-Throughput the Search of Human Rhinovirus Virtual Screening Strategies for Coat Protein Inhibitors

Steindl, T. and Langer, T.

Qsar & Combinatorial Science 2005. 24(4): 470-479


16. 57737 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Bicyclic carbohydrate compounds useful in the treatment of infections caused by Herpesviridae

Sas, Benedikt, Van Hemel, Johan, Vandenkerckhove, Jan, Peys, Eric, Van Der Eycken, Johan, Ruttens, Bart, and Blom, Petra

PATENT: US 2005090452 ISSUE DATE: 20050428

APPLICATION: 69 PP: 18 pp.


17. 57738 DMID-LS-97; WOS-DMID-7/18/2005 ; DMID-LSLOAD

Synthesis and Anti-Influenza Virus Activity of Polyoxometalates Containing Amantadine

Liu, S. et al.

Acta Chimica Sinica 2005. 63(12): 1069-1074


18. 57739 DMID-LS-97; WOS-DMID-7/18/2005 ; DMID-LSLOAD

Comparison of the Antiviral Activity of Acivicin (At125) Against Herpesvirus Infection in Human Lens and G-Glutamyltranspeptidase Positive Conjunctival Cells

Langford, M. et al.

Investigative Ophthalmology & Visual Science 2005. 46


19. 57740 DMID-LS-97; WOS-DMID-7/18/2005 ; DMID-LSLOAD

In Vitro Antiviral Activity of Chamaecrista Nictitans (Fabaceae) Against Herpes Simplex Virus: Biological Characterization of Mechanisms of Action

Uribe, L., Olarte, E., and Castillo, G.

Revista De Biologia Tropical 2004. 52(3): 807-816


20. 57741 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Papain-Like Protease 2 (PLP2) from Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV): Expression, Purification, Characterization, and Inhibition

Han, Yu-San, Chang, Gu-Gang, Juo, Chiun-Gung, Lee, Hong-Jen, Yeh, Shiou-Hwei, Hsu, John Tsu-An, and Chen, Xin

Biochemistry 2005. 44(30): 10349-10359

21. 57742 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Use of sialic acid, analogues of sialic acid, and antibodies to sialidases as anti-infectious agents and anti-inflammatory agents

Cross, Alan and Stamatos, Nicholas

PATENT: WO 2005056047 ISSUE DATE: 20050623

APPLICATION: 2004 PP: 51 pp.

ASSIGNEE: (United States Army Medical Research and Materiel Command, USA

22. 57743 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

SiRNA targeting SARS nsp-1, nsp-9 or spike gene for anti-SARS coronavirus therapy

Tang, Quinn T, Lu, Patrick Y, Xie, Frank Y, Liu, Yijia, Xu, Jun, and Woodle, Martin C

PATENT: WO 2005019410 ISSUE DATE: 20050303

APPLICATION: 2004 PP: 48 pp.

ASSIGNEE: (Intradigm Corporation, USA

23. 57744 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Human papillomavirus inhibitors and screening system reagentss

Meneses, Patricio I, Koehler, Angela N, Wong, Jason C, Howley, Peter M, and Schreiber, Stuart L

PATENT: US 2005123902 ISSUE DATE: 20050609

APPLICATION: 2004-64975 PP: 23 pp.

ASSIGNEE: (President and Fellows of Harvard College, USA

24. 57745 DMID-LS-97; SCIFINDER-DMID-7/18/2005 ; DMID-LSLOAD

Indoles and azaindoles as inhibitors of hepatitis C virus polymerase, their preparation, pharmaceutical compositions, and use as antiviral agents

Avolio, Salvatore, Harper, Steven, Narjes, Frank, Pacini, Barbara, and Rowley, Michael

PATENT: WO 2005034941 ISSUE DATE: 20050421

APPLICATION: 2004 PP: 41 pp.

ASSIGNEE: (Istituto di Ricerche di Biologia Molecolare p Angeletti S.p.A., Italy

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