ONLINE DATABASE SEARCH - DMID-LS-99-MEMO
1. 57775 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone
Prabhu, Ramesh, Vittal, Padmaja, Yin, Qinyan, Flemington, Erik, Garry, Robert, Robichaux, William H, and Dash, Srikanta
Journal of Medical Virology 2005. 76(4): 511-519
2. 57776 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061
Lin, C, Gates, CA, Rao, BG, Brennan, DL, Fulghum, JF, Luong, YP, Frantz, JD, Lin, K, Ma, S, Wei, YY, Perni, RB, and Kwong, AD
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16087668&dopt=abstract
3. 57777 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Nucleotide analogs as novel anti-hepatitis B virus agents
Iyer, RP, Padmanabhan, S, Zhang, G, Morrey, JD, and Korba, BE
Curr Opin Pharmacol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16087397&dopt=abstract
4. 57778 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Novel inhibitors of the hepatitis C virus NS3 proteinase
Bennett, F, Liu, YT, Saksena, AK, Arasappan, A, Butkiewicz, N, Dasmahapatra, B, Pichardo, JS, Njoroge, FG, Patel, NM, Huang, Y, and Yang, X
Bioorg Med Chem Lett 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16087334&dopt=abstract
5. 57779 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
Simmons, G, Gosalia, DN, Rennekamp, AJ, Reeves, JD, Diamond, SL, and Bates, P
Proc Natl Acad Sci U S A 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16081529&dopt=abstract
6. 57780 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
2-5A antisense treatment of respiratory syncytial virus
Leaman, DW
Curr Opin Pharmacol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16081320&dopt=abstract
7. 57781 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Strategies for containing an emerging influenza pandemic in Southeast Asia
Ferguson, NM, Cummings, DA, Cauchemez, S, Fraser, C, Riley, S, Meeyai, A, Iamsirithaworn, S, and Burke, DS
Nature 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16079797&dopt=abstract
8. 57782 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD
Safety, Pharmacodynamic (Pd) and Pharmacokinetic (Pk) Profiles of Cpg 10101 (Actilon-Tm), a Novel Tlr9 Agonist: Comparison in Normal Volunteers and Hcv Infected Individuals
Bacon, B. et al.
Gastroenterology 2005. 128(4): A696
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000228619305472
9. 57783 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Containing Pandemic Influenza at the Source
Longini, Jr IM, Nizam, A, Xu, S, Ungchusak, K, Hanshaoworakul, W, Cummings, DA, and Halloran, EM
Science 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16079251&dopt=abstract
10. 57784 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design
Venkatraman, S, Njoroge, FG, Girijavallabhan, VM, Madison, VS, Yao, NH, Prongay, AJ, Butkiewicz, N, and Pichardo, J
J Med Chem 2005. 48(16): 5088-91
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16078825&dopt=abstract
11. 57785 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Carbocyclic N-3 isonucleosides as SAHase inhibitors for antiviral chemotherapeutics
Bakke, Brian A, Mosley, Sylvester L, Sadler, Joshua M, Sunkara, Narsesh K, and Seley, Katherine L
Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005 2005.: MEDI-166
12. 57786 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Utilization of the embryonated egg for in vivo evaluation of the anti-influenza virus activity of neuraminidase inhibitors
Sauerbrei, A, Haertl, A, Brandstaedt, A, Schmidtke, M, and Wutzler, P
Med Microbiol Immunol (Berl) 2005.: 1-7
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16059699&dopt=abstract
13. 57787 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD
A Phase 2 Study to Assess Antiviral Response, Safety, and Pharmacokinetics of Albuferon(Tm) in Ifn-Oc Naive Subjects With Genotype 1 Chronic Hepatitis C
Bain, V. et al.
Journal of Hepatology 2005. 42: 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000229024000019
14. 57788 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD
Telbivudine (Ldt) Preferentially Inhibits Second (Plus) Strand Hbv Dna Synthesis
Seifer, M. et al.
Journal of Hepatology 2005. 42: 151
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000229024000413
15. 57789 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Antiviral drug discovery and development: Where chemistry meets with biomedicine
De Clercq, E
Antiviral Res 2005. 67(2): 56-75
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16046240&dopt=abstract
16. 57790 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Perspective: Marburg and Ebola - Arming ourselves against the deadly filoviruses
Peters, CJ
New England Journal of Medicine 2005. 352(25): 2571-2573
17. 57791 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Nitric oxide radical suppresses replication of wild-type dengue 2 viruses in vitro
Charnsilpa, W, Takhampunya, R, Endy, TP, Mammen, MP Jr, Libraty, DH, and Ubol, S
J Med Virol 2005. 77(1): 89-95
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16032750&dopt=abstract
18. 57792 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD
Chondroitin sulfate characterized by the E disaccharide unit is a potent inhibitor of herpes simplex virus infectivity and provides the virus binding sites on gro2c cells
Bergefall, K, Trybala, E, Johansson, M, Uyama, T, Naito, S, Yamada, S, Kitagawa, H, Sugahara, K, and Bergstrom, T
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16027159&dopt=abstract
19. 57793 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Preparation of imidazo[4,5-c]pyridine derivatives as antiviral agents
Puerstinger, Gerhard, Bondy, Steven S, Dowdy, Eric Davis, Kim, Choung U, Oare, David A, Neyts, Johan, and Zia, Vahid
PATENT: WO 2005063744 ISSUE DATE: 20050714
APPLICATION: 2004 PP: 265 pp.
ASSIGNEE: (K. U. Leuven Research & Development, Belg. and Gilead Sciences, Inc.
20. 57794 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Antiviral agents and methods of use
Striker, Robert T, Elfarra, Adnan A, Gunnarsdottir, Sjofn, and Hoover, Spencer W
PATENT: US 2005119284 ISSUE DATE: 20050602
APPLICATION: 2004-56321 PP: 21 pp.
ASSIGNEE: (Wisconsin Alumni Research Foundation, USA
21. 57795 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD
Amino Acid Ester Prodrugs of 2-Bromo-5,6-Dichloro-1-(Beta-D-Ribofuranosyl) Benzimidazole Enhance Metabolic Stability in Vitro and in Vivo
Lorenzi, P. et al.
Journal of Pharmacology and Experimental Therapeutics 2005. 314(2): 883-890
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000230550300049
22. 57796 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Virus-encoded chemokine receptors - putative novel antiviral drug targets
Rosenkilde, Mette M
Neuropharmacology 2005. 48(1): 1-13
23. 57797 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Synthesis of novel test compounds for antiviral chemotherapy of severe acute respiratory syndrome (SARS)
Kesel, Andreas J
Current Medicinal Chemistry 2005. 12(18): 2095-2162
24. 57798 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
Preparation of peptides as protease inhibitors
Yang, Syaulan, Wu, Jen-Dar, Su, Feng-Yih, Kuo, Chun-Wei, Chen, Wen-Chang, Hsu, Ming-Chu, Xiang, Yibin, Wang, Ching-Cheng, and Liao, Shao-Ying
PATENT: US 2005143320 ISSUE DATE: 20050630
APPLICATION: 2005 PP: 46 pp., Cont.-in-part of U.S. Ser. No. 24,929.
ASSIGNEE: (Taigen Biotechnology, Taiwan
25. 57799 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD
A preparation of mesylate salt of indole derivative, useful as antiviral agent
Glushkov, RG, Maksimov, VA, Mart'yanov, VA, Khamitov, RA, and Shuster, AM
PATENT: RU 2255086 ISSUE DATE: 20050627
APPLICATION: 2004-46336 PP: No pp. given
ASSIGNEE: (Zakrytoe Aktsionernoe Obshchestvo \"Masterklon\", Russia