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1. 57775 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone

Prabhu, Ramesh, Vittal, Padmaja, Yin, Qinyan, Flemington, Erik, Garry, Robert, Robichaux, William H, and Dash, Srikanta

Journal of Medical Virology 2005. 76(4): 511-519

2. 57776 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061

Lin, C, Gates, CA, Rao, BG, Brennan, DL, Fulghum, JF, Luong, YP, Frantz, JD, Lin, K, Ma, S, Wei, YY, Perni, RB, and Kwong, AD

J Biol Chem 2005.


3. 57777 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Nucleotide analogs as novel anti-hepatitis B virus agents

Iyer, RP, Padmanabhan, S, Zhang, G, Morrey, JD, and Korba, BE

Curr Opin Pharmacol 2005.


4. 57778 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Novel inhibitors of the hepatitis C virus NS3 proteinase

Bennett, F, Liu, YT, Saksena, AK, Arasappan, A, Butkiewicz, N, Dasmahapatra, B, Pichardo, JS, Njoroge, FG, Patel, NM, Huang, Y, and Yang, X

Bioorg Med Chem Lett 2005.


5. 57779 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

Simmons, G, Gosalia, DN, Rennekamp, AJ, Reeves, JD, Diamond, SL, and Bates, P

Proc Natl Acad Sci U S A 2005.


6. 57780 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

2-5A antisense treatment of respiratory syncytial virus

Leaman, DW

Curr Opin Pharmacol 2005.


7. 57781 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Strategies for containing an emerging influenza pandemic in Southeast Asia

Ferguson, NM, Cummings, DA, Cauchemez, S, Fraser, C, Riley, S, Meeyai, A, Iamsirithaworn, S, and Burke, DS

Nature 2005.


8. 57782 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD

Safety, Pharmacodynamic (Pd) and Pharmacokinetic (Pk) Profiles of Cpg 10101 (Actilon-Tm), a Novel Tlr9 Agonist: Comparison in Normal Volunteers and Hcv Infected Individuals

Bacon, B. et al.

Gastroenterology 2005. 128(4): A696


9. 57783 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Containing Pandemic Influenza at the Source

Longini, Jr IM, Nizam, A, Xu, S, Ungchusak, K, Hanshaoworakul, W, Cummings, DA, and Halloran, EM

Science 2005.


10. 57784 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design

Venkatraman, S, Njoroge, FG, Girijavallabhan, VM, Madison, VS, Yao, NH, Prongay, AJ, Butkiewicz, N, and Pichardo, J

J Med Chem 2005. 48(16): 5088-91


11. 57785 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Carbocyclic N-3 isonucleosides as SAHase inhibitors for antiviral chemotherapeutics

Bakke, Brian A, Mosley, Sylvester L, Sadler, Joshua M, Sunkara, Narsesh K, and Seley, Katherine L

Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005 2005.: MEDI-166

12. 57786 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Utilization of the embryonated egg for in vivo evaluation of the anti-influenza virus activity of neuraminidase inhibitors

Sauerbrei, A, Haertl, A, Brandstaedt, A, Schmidtke, M, and Wutzler, P

Med Microbiol Immunol (Berl) 2005.: 1-7


13. 57787 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD

A Phase 2 Study to Assess Antiviral Response, Safety, and Pharmacokinetics of Albuferon(Tm) in Ifn-Oc Naive Subjects With Genotype 1 Chronic Hepatitis C

Bain, V. et al.

Journal of Hepatology 2005. 42: 9


14. 57788 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD

Telbivudine (Ldt) Preferentially Inhibits Second (Plus) Strand Hbv Dna Synthesis

Seifer, M. et al.

Journal of Hepatology 2005. 42: 151


15. 57789 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Antiviral drug discovery and development: Where chemistry meets with biomedicine

De Clercq, E

Antiviral Res 2005. 67(2): 56-75


16. 57790 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Perspective: Marburg and Ebola - Arming ourselves against the deadly filoviruses

Peters, CJ

New England Journal of Medicine 2005. 352(25): 2571-2573

17. 57791 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Nitric oxide radical suppresses replication of wild-type dengue 2 viruses in vitro

Charnsilpa, W, Takhampunya, R, Endy, TP, Mammen, MP Jr, Libraty, DH, and Ubol, S

J Med Virol 2005. 77(1): 89-95


18. 57792 DMID-LS-99; PUBMED-DMID-8/15/2005 ; DMID-LSLOAD

Chondroitin sulfate characterized by the E disaccharide unit is a potent inhibitor of herpes simplex virus infectivity and provides the virus binding sites on gro2c cells

Bergefall, K, Trybala, E, Johansson, M, Uyama, T, Naito, S, Yamada, S, Kitagawa, H, Sugahara, K, and Bergstrom, T

J Biol Chem 2005.


19. 57793 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Preparation of imidazo[4,5-c]pyridine derivatives as antiviral agents

Puerstinger, Gerhard, Bondy, Steven S, Dowdy, Eric Davis, Kim, Choung U, Oare, David A, Neyts, Johan, and Zia, Vahid

PATENT: WO 2005063744 ISSUE DATE: 20050714

APPLICATION: 2004 PP: 265 pp.

ASSIGNEE: (K. U. Leuven Research & Development, Belg. and Gilead Sciences, Inc.

20. 57794 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Antiviral agents and methods of use

Striker, Robert T, Elfarra, Adnan A, Gunnarsdottir, Sjofn, and Hoover, Spencer W

PATENT: US 2005119284 ISSUE DATE: 20050602

APPLICATION: 2004-56321 PP: 21 pp.

ASSIGNEE: (Wisconsin Alumni Research Foundation, USA

21. 57795 DMID-LS-99; WOS-DMID-8/15/2005 ; DMID-LSLOAD

Amino Acid Ester Prodrugs of 2-Bromo-5,6-Dichloro-1-(Beta-D-Ribofuranosyl) Benzimidazole Enhance Metabolic Stability in Vitro and in Vivo

Lorenzi, P. et al.

Journal of Pharmacology and Experimental Therapeutics 2005. 314(2): 883-890

22. 57796 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Virus-encoded chemokine receptors - putative novel antiviral drug targets

Rosenkilde, Mette M

Neuropharmacology 2005. 48(1): 1-13

23. 57797 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Synthesis of novel test compounds for antiviral chemotherapy of severe acute respiratory syndrome (SARS)

Kesel, Andreas J

Current Medicinal Chemistry 2005. 12(18): 2095-2162

24. 57798 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

Preparation of peptides as protease inhibitors

Yang, Syaulan, Wu, Jen-Dar, Su, Feng-Yih, Kuo, Chun-Wei, Chen, Wen-Chang, Hsu, Ming-Chu, Xiang, Yibin, Wang, Ching-Cheng, and Liao, Shao-Ying

PATENT: US 2005143320 ISSUE DATE: 20050630

APPLICATION: 2005 PP: 46 pp., Cont.-in-part of U.S. Ser. No. 24,929.

ASSIGNEE: (Taigen Biotechnology, Taiwan

25. 57799 DMID-LS-99; SCIFINDER-DMID-8/15/2005 ; DMID-LSLOAD

A preparation of mesylate salt of indole derivative, useful as antiviral agent

Glushkov, RG, Maksimov, VA, Mart'yanov, VA, Khamitov, RA, and Shuster, AM

PATENT: RU 2255086 ISSUE DATE: 20050627

APPLICATION: 2004-46336 PP: No pp. given

ASSIGNEE: (Zakrytoe Aktsionernoe Obshchestvo \"Masterklon\", Russia

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